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The map label for this gene is fabF [H]

Identifier: 220918029

GI number: 220918029

Start: 3243169

End: 3244410

Strand: Reverse

Name: fabF [H]

Synonym: A2cp1_2930

Alternate gene names: 220918029

Gene position: 3244410-3243169 (Counterclockwise)

Preceding gene: 220918030

Following gene: 220918028

Centisome position: 64.51

GC content: 71.34

Gene sequence:

>1242_bases
ATGAGCAGGCGCCGTGTCGTCGTCACAGGACTGGGGCTCGTCTCGCCCGTGGGCATCGGGGTGGAGGAGTCCTGGAGCGC
GCTCGTGGCCGGCAAGAGCGGCATCGGGCCCATCACCCTCTTCGACGCCTCCACCTACCCGACGCGCATCGCCGGCGAGG
TGAAGGCCTTCGATCCCACCCGCTTCATGGATCGCAAGGAGGCCCGGCGGAACGACCGCTTCATCCAGTTCGCGCTCGCC
GCCGCCGACATGGCCATGAAGGACTCGGGCCTCGACATGTCGAAGGAGGACCCCGTGCGCGTCGGCGCCATCGTCGGCGC
GGGCATCGGCGGCCTCGGCACGATCGAGGACGAGCACAAGACGTTGCTGGAGAAGGGCGTCCGCAAGATCGGCCCGTTCT
TCATCCCGTCGCTCATCATCAACCTGGCCCCGGGCCAGATCAGCATGAAGTACGGGATGCAGGGCCCGAACTTCTCGCCG
GTCTCGGCCTGCGCCACCGGCAACCACTCCATCGGCGACGCGATGCTCTACATCGAGCGCGGCCTCGCCGACGTGATCAT
CGCGGGCGGCTGCGAGGCCACCATCACGCCGCTCGGCATCGGCGGCTTCTGCGCGGCCCGGGCGCTCTCCGAGCGCAACG
ACGCGCCCGAGAAGGCGAGCCGCCCGTTCGACAAGGGCCGCGACGGCTTCGTGGCCGGCGAGGGCGCTGGCCTGGTGGTG
CTCGAGGAGTACGAGCACGCCCGCAAGCGCGGCGCGCGCATCTACGCGGAGCTGGCCGGCTACGGCGCCAGCGCCGACGC
GTACCACATCACCGCGCCGGCCGAGGGCGGCGAGGGCGGCGCGCGCGCGGTCCGCATGGCGCTGCAGGACGCCGGCGTCG
CGCCCGAGCAGGTCGGCTACGTGAACACCCACGGCACCTCGACGCCGGTCGGCGACGTGGCCGAGTGCCAGGGCATCAAG
CGCGTCTTCGGGGAGCACGCGAAGCACGGCCTGATGGTCTCCTCGACCAAGTCCATGACCGGCCACCTGCTGGGCGGCGC
CGGCGGGCTCGAGGCGGTGGTGACGGTCCTCGCCATCTCGCGCGGCGTGCTGCCGCCGACCATCAACGTCGAGGACCAGG
ACCCGCAGTGCGACCTCGACGTCGTCCCGAACACGGCGCGCGAGGTGCGCGTCGACGTGGCGGTCTCGAACTCCTTCGGG
TTCGGCGGCACGAACGCCGTGGTGCTCTTCAAGCGCGTGTAG

Upstream 100 bases:

>100_bases
AAGAAGTAGCCGCGGCTCCGGAGTCGGTACCGCGCGCGGGGGCGAGGCCGGGGGGCCTCGCCGCCGCCGCACGCGCTCTT
TCCGAGGAGAGGTGAACCAG

Downstream 100 bases:

>100_bases
CGGCCCGGCCGGCCGCGACCCCCCGAGGCGCCGCCCCGCCGCGCGGGGTCGGCGCCTCTCGCGTTCCGGGGGAGCCGCCG
GCCGGTGGCGGCCCATCGCC

Product: 3-oxoacyl-(acyl-carrier-protein) synthase 2

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSRRRVVVTGLGLVSPVGIGVEESWSALVAGKSGIGPITLFDASTYPTRIAGEVKAFDPTRFMDRKEARRNDRFIQFALA
AADMAMKDSGLDMSKEDPVRVGAIVGAGIGGLGTIEDEHKTLLEKGVRKIGPFFIPSLIINLAPGQISMKYGMQGPNFSP
VSACATGNHSIGDAMLYIERGLADVIIAGGCEATITPLGIGGFCAARALSERNDAPEKASRPFDKGRDGFVAGEGAGLVV
LEEYEHARKRGARIYAELAGYGASADAYHITAPAEGGEGGARAVRMALQDAGVAPEQVGYVNTHGTSTPVGDVAECQGIK
RVFGEHAKHGLMVSSTKSMTGHLLGGAGGLEAVVTVLAISRGVLPPTINVEDQDPQCDLDVVPNTAREVRVDVAVSNSFG
FGGTNAVVLFKRV

Sequences:

>Translated_413_residues
MSRRRVVVTGLGLVSPVGIGVEESWSALVAGKSGIGPITLFDASTYPTRIAGEVKAFDPTRFMDRKEARRNDRFIQFALA
AADMAMKDSGLDMSKEDPVRVGAIVGAGIGGLGTIEDEHKTLLEKGVRKIGPFFIPSLIINLAPGQISMKYGMQGPNFSP
VSACATGNHSIGDAMLYIERGLADVIIAGGCEATITPLGIGGFCAARALSERNDAPEKASRPFDKGRDGFVAGEGAGLVV
LEEYEHARKRGARIYAELAGYGASADAYHITAPAEGGEGGARAVRMALQDAGVAPEQVGYVNTHGTSTPVGDVAECQGIK
RVFGEHAKHGLMVSSTKSMTGHLLGGAGGLEAVVTVLAISRGVLPPTINVEDQDPQCDLDVVPNTAREVRVDVAVSNSFG
FGGTNAVVLFKRV
>Mature_412_residues
SRRRVVVTGLGLVSPVGIGVEESWSALVAGKSGIGPITLFDASTYPTRIAGEVKAFDPTRFMDRKEARRNDRFIQFALAA
ADMAMKDSGLDMSKEDPVRVGAIVGAGIGGLGTIEDEHKTLLEKGVRKIGPFFIPSLIINLAPGQISMKYGMQGPNFSPV
SACATGNHSIGDAMLYIERGLADVIIAGGCEATITPLGIGGFCAARALSERNDAPEKASRPFDKGRDGFVAGEGAGLVVL
EEYEHARKRGARIYAELAGYGASADAYHITAPAEGGEGGARAVRMALQDAGVAPEQVGYVNTHGTSTPVGDVAECQGIKR
VFGEHAKHGLMVSSTKSMTGHLLGGAGGLEAVVTVLAISRGVLPPTINVEDQDPQCDLDVVPNTAREVRVDVAVSNSFGF
GGTNAVVLFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=45.6730769230769, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI223972627, Length=149, Percent_Identity=51.6778523489933, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI41872631, Length=425, Percent_Identity=27.2941176470588, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=56.0386473429952, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=39.1826923076923, Blast_Score=254, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=36.5384615384615, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=41.5094339622642, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI212642053, Length=360, Percent_Identity=26.6666666666667, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=356, Percent_Identity=23.876404494382, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=450, Percent_Identity=36.4444444444444, Blast_Score=288, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24644341, Length=413, Percent_Identity=46.2469733656174, Blast_Score=340, Evalue=7e-94,
Organism=Drosophila melanogaster, GI19920632, Length=379, Percent_Identity=24.5382585751979, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI221330659, Length=379, Percent_Identity=24.5382585751979, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24581345, Length=428, Percent_Identity=23.8317757009346, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43094; Mature: 42962

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRVVVTGLGLVSPVGIGVEESWSALVAGKSGIGPITLFDASTYPTRIAGEVKAFDPT
CCCCEEEEEECCHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCEECCCEECCCCH
RFMDRKEARRNDRFIQFALAAADMAMKDSGLDMSKEDPVRVGAIVGAGIGGLGTIEDEHK
HHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHH
TLLEKGVRKIGPFFIPSLIINLAPGQISMKYGMQGPNFSPVSACATGNHSIGDAMLYIER
HHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHH
GLADVIIAGGCEATITPLGIGGFCAARALSERNDAPEKASRPFDKGRDGFVAGEGAGLVV
CCEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCEEECCCCCEEE
LEEYEHARKRGARIYAELAGYGASADAYHITAPAEGGEGGARAVRMALQDAGVAPEQVGY
EHHHHHHHHHCCEEEEHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHCCE
VNTHGTSTPVGDVAECQGIKRVFGEHAKHGLMVSSTKSMTGHLLGGAGGLEAVVTVLAIS
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECCCCHHHHHHHHHHHH
RGVLPPTINVEDQDPQCDLDVVPNTAREVRVDVAVSNSFGFGGTNAVVLFKRV
CCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEECCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
SRRRVVVTGLGLVSPVGIGVEESWSALVAGKSGIGPITLFDASTYPTRIAGEVKAFDPT
CCCEEEEEECCHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCEECCCEECCCCH
RFMDRKEARRNDRFIQFALAAADMAMKDSGLDMSKEDPVRVGAIVGAGIGGLGTIEDEHK
HHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHH
TLLEKGVRKIGPFFIPSLIINLAPGQISMKYGMQGPNFSPVSACATGNHSIGDAMLYIER
HHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHH
GLADVIIAGGCEATITPLGIGGFCAARALSERNDAPEKASRPFDKGRDGFVAGEGAGLVV
CCEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCEEECCCCCEEE
LEEYEHARKRGARIYAELAGYGASADAYHITAPAEGGEGGARAVRMALQDAGVAPEQVGY
EHHHHHHHHHCCEEEEHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHCCE
VNTHGTSTPVGDVAECQGIKRVFGEHAKHGLMVSSTKSMTGHLLGGAGGLEAVVTVLAIS
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECCCCHHHHHHHHHHHH
RGVLPPTINVEDQDPQCDLDVVPNTAREVRVDVAVSNSFGFGGTNAVVLFKRV
CCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEECCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]