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The map label for this gene is mdtA [H]

Identifier: 220917881

GI number: 220917881

Start: 3069537

End: 3070655

Strand: Direct

Name: mdtA [H]

Synonym: A2cp1_2782

Alternate gene names: 220917881

Gene position: 3069537-3070655 (Clockwise)

Preceding gene: 220917880

Following gene: 220917882

Centisome position: 61.03

GC content: 82.04

Gene sequence:

>1119_bases
ATGCCGCCGCTCCGCCCCGCCCTGCTCCTCGCGATCGCCGCGACCGCCTGCGGCCGCCGCGGCGCCGACCGGCCCCCGCC
GCCTCCCGCGCCGGCGACCGCCCCCGCGCCCGCCGCGGGGCCGGCGGCCGCCGCCGCCCACCTCGCCGCCCCGGAGCGCA
TCCGCTTCGCGCCGCGCGTCACCGCCACCGGGACGCTGAAGGCGCGCCAGGCCTCGGCGCTGGCGGTCAGCGTGGCCGGC
ACGCTGGAGCGCGTCGCGGTGCGCCGCGGCCAGGAGGTGCGCGAGGGAGCGCTCCTGGCGGCGCTCGACCCCGGCGCCGC
CGCGGCGGCGGTCCGGCAGGCCGAGGCGGCGGTGGCGGCCGCCCGGGCGCAGCTCGCGCTGGCGGAGGACGCGCTCGCGC
GCACCGAGCGGCTCCGCCGCGAGGAGGGCGCGTCGGAGGCGCAGGCCACGCAGGCGCGCGCGCAGCGCGACCTCGTCGCC
GCGCACCTCGCCGCGGCCCAGGCGCAGGCGGAGCAGGCGCGGGTCCACCTGTCGCACCACCGGCTGGTCGCGCCGTTCCC
CGGGGTCGTCACCCGCGTGCCGGACGGCGTGGGCATCGCCGTCTCGCCCGGCGTCCCGCTCGTCACGCTCGTCACCACGC
GCGAGCTGGTGCTCGAGACCTCCCTCACGCAGTCCGAGGCCGCCGAGCTGCGCCCGGGCGCCCGTGCGACGGTGTCGGTC
CCCGGCACCGGCGCGCGCGCCGCGGACGCGGTGGTGACGGTGGTGGTCCCCGCGGTGGACCCCGCCACGAACCGCGTGCC
GGTGGAGATCGCCGTCGCCAACGCCGGCGGCCGCTTCCTCGCGAACGCCTACGCGCGGGCCGAGCTGCCCCGCGGGGCGG
AGCGCGAGGCGTGGCGCGTGCCTGCCGCGGCGCTGGTGCAGCGCGCCGGTGGTCACGCCGTGTGGGTGGCCGGCGGGGAC
GGCCGGGCGCGGACGCTGCCGGTGCGCCTGCTCGCCGAGGACGGCGAGACGGCGGTGGTGCTGCCGGAGGGCGGCGCCTG
GCCGGAGGGGCTGCGCGTGGTCACCGACCCGCCGGTCGGCCTCGCCGAGGGCACGGCAGTGGCGCAGGTGCGTGGATGA

Upstream 100 bases:

>100_bases
ATCTTCTACGAGGGCATGGCCGGGCCCGCCGCGCGCGCCGCCTCCGCCCGCGCCCGCCGCACCGCAACCTGACCCACCGG
TCAGCCCCGGAGACCCGACG

Downstream 100 bases:

>100_bases
CGCTCTCCGACGTCGCCATCCGCAGGCCCGTCTTCACCGCCATGATGTCGGTGACGCTGGTGGTGCTCGGGCTGCTCGGC
CTGCGCCGGCTCGGCACCGA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MPPLRPALLLAIAATACGRRGADRPPPPPAPATAPAPAAGPAAAAAHLAAPERIRFAPRVTATGTLKARQASALAVSVAG
TLERVAVRRGQEVREGALLAALDPGAAAAAVRQAEAAVAAARAQLALAEDALARTERLRREEGASEAQATQARAQRDLVA
AHLAAAQAQAEQARVHLSHHRLVAPFPGVVTRVPDGVGIAVSPGVPLVTLVTTRELVLETSLTQSEAAELRPGARATVSV
PGTGARAADAVVTVVVPAVDPATNRVPVEIAVANAGGRFLANAYARAELPRGAEREAWRVPAAALVQRAGGHAVWVAGGD
GRARTLPVRLLAEDGETAVVLPEGGAWPEGLRVVTDPPVGLAEGTAVAQVRG

Sequences:

>Translated_372_residues
MPPLRPALLLAIAATACGRRGADRPPPPPAPATAPAPAAGPAAAAAHLAAPERIRFAPRVTATGTLKARQASALAVSVAG
TLERVAVRRGQEVREGALLAALDPGAAAAAVRQAEAAVAAARAQLALAEDALARTERLRREEGASEAQATQARAQRDLVA
AHLAAAQAQAEQARVHLSHHRLVAPFPGVVTRVPDGVGIAVSPGVPLVTLVTTRELVLETSLTQSEAAELRPGARATVSV
PGTGARAADAVVTVVVPAVDPATNRVPVEIAVANAGGRFLANAYARAELPRGAEREAWRVPAAALVQRAGGHAVWVAGGD
GRARTLPVRLLAEDGETAVVLPEGGAWPEGLRVVTDPPVGLAEGTAVAQVRG
>Mature_371_residues
PPLRPALLLAIAATACGRRGADRPPPPPAPATAPAPAAGPAAAAAHLAAPERIRFAPRVTATGTLKARQASALAVSVAGT
LERVAVRRGQEVREGALLAALDPGAAAAAVRQAEAAVAAARAQLALAEDALARTERLRREEGASEAQATQARAQRDLVAA
HLAAAQAQAEQARVHLSHHRLVAPFPGVVTRVPDGVGIAVSPGVPLVTLVTTRELVLETSLTQSEAAELRPGARATVSVP
GTGARAADAVVTVVVPAVDPATNRVPVEIAVANAGGRFLANAYARAELPRGAEREAWRVPAAALVQRAGGHAVWVAGGDG
RARTLPVRLLAEDGETAVVLPEGGAWPEGLRVVTDPPVGLAEGTAVAQVRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=360, Percent_Identity=26.1111111111111, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081796, Length=297, Percent_Identity=25.2525252525253, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37686; Mature: 37555

Theoretical pI: Translated: 11.30; Mature: 11.30

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLRPALLLAIAATACGRRGADRPPPPPAPATAPAPAAGPAAAAAHLAAPERIRFAPRV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHEEECCCE
TATGTLKARQASALAVSVAGTLERVAVRRGQEVREGALLAALDPGAAAAAVRQAEAAVAA
EECCCEEHHCCCEEEEEHHHHHHHHHHHCCCHHHCCCEEEEECCCHHHHHHHHHHHHHHH
ARAQLALAEDALARTERLRREEGASEAQATQARAQRDLVAAHLAAAQAQAEQARVHLSHH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
RLVAPFPGVVTRVPDGVGIAVSPGVPLVTLVTTRELVLETSLTQSEAAELRPGARATVSV
EEECCCCCHHHHCCCCCCEEECCCCCEEEEEEHHHHHHHHCCCHHHHHHCCCCCCEEEEC
PGTGARAADAVVTVVVPAVDPATNRVPVEIAVANAGGRFLANAYARAELPRGAEREAWRV
CCCCCCHHCEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHCC
PAAALVQRAGGHAVWVAGGDGRARTLPVRLLAEDGETAVVLPEGGAWPEGLRVVTDPPVG
CHHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCCEEEECCCCC
LAEGTAVAQVRG
CCCCCEEEEECC
>Mature Secondary Structure 
PPLRPALLLAIAATACGRRGADRPPPPPAPATAPAPAAGPAAAAAHLAAPERIRFAPRV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHEEECCCE
TATGTLKARQASALAVSVAGTLERVAVRRGQEVREGALLAALDPGAAAAAVRQAEAAVAA
EECCCEEHHCCCEEEEEHHHHHHHHHHHCCCHHHCCCEEEEECCCHHHHHHHHHHHHHHH
ARAQLALAEDALARTERLRREEGASEAQATQARAQRDLVAAHLAAAQAQAEQARVHLSHH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
RLVAPFPGVVTRVPDGVGIAVSPGVPLVTLVTTRELVLETSLTQSEAAELRPGARATVSV
EEECCCCCHHHHCCCCCCEEECCCCCEEEEEEHHHHHHHHCCCHHHHHHCCCCCCEEEEC
PGTGARAADAVVTVVVPAVDPATNRVPVEIAVANAGGRFLANAYARAELPRGAEREAWRV
CCCCCCHHCEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHCC
PAAALVQRAGGHAVWVAGGDGRARTLPVRLLAEDGETAVVLPEGGAWPEGLRVVTDPPVG
CHHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCCEEEECCCCC
LAEGTAVAQVRG
CCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA