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The map label for this gene is atpA

Identifier: 220917862

GI number: 220917862

Start: 3048594

End: 3050333

Strand: Reverse

Name: atpA

Synonym: A2cp1_2763

Alternate gene names: 220917862

Gene position: 3050333-3048594 (Counterclockwise)

Preceding gene: 220917863

Following gene: 220917861

Centisome position: 60.65

GC content: 77.07

Gene sequence:

>1740_bases
ATGAGCGGGACGCTGATGCGGATGGCCGGACCGACGGTGGTGGCGGAGGGCCTCTCCGGCGCGAGCCTGAACGAGGTGGT
GCGCGTCGGCGAGGAGCGGCTGCTCGGCGAGATCATCCGCATCGAGGGCGACCGCGCCACCATCCAGGTCTACGAGGAGA
CCGCGGGGCTCGCGCTGGGCGAGCCGGTGGAGGCCTCGGGCGAGCCGCTCGCGGTGGAGCTCGGCCCGGGGCTGCTCGGC
TCGGTGTTCGACGGCGTGCAGCGTCCGCTCTCCGAGCTGGCCGCGCGCGAGGGCGACTTCCTGGGCCGCGGCGCCTCGCT
GCCGGCGCTGGACCGCACGCGCGCCTGGGAGTTCGAGCCCGCCGTCGCGCCCGGCGACCGCGTCGAGGGCGGCGCGCGCC
TGGGCGTGGCGCGCGCGCCGGGCGCCCCCGACCACCCGGTGGTGGTCCCGCCCGGCGTGACCGGTCGCGTCGCGGAGGTC
CGCGGCGGCGCGCGGCGCGTGGACGAGCCGGCGGTGCTGCTGGAAGGGGGCGCCACGCTCGCGCTGCTGGAGCGCTGGCC
GGTGCGCCGCCCCCGCCCGGCGCGCCGCCGCCTCCCGCCGGACGTGCCGTTCCTCACCGGGCAGCGGGTGCTGGACTGCT
TCTTCCCGGTCTCGGCGGGCGGGACCGCGGTGGTGCCGGGCGGCTTCGGCACCGGCAAGACGGTGCTGGAGCAGAGCCTG
GCGAAGTGGGCCGCCGCCGACGTGGTCGTCTACGTGGGCTGCGGCGAGCGCGGCAACGAGATGTCCGAGGTGCTGGACGA
GTTCCCGCGGCTCGAGGACCCGCGCACCGGCGGGCCGCTGCTCGCGCGCACGGTGATGATCGTGAACACCTCGAACATGC
CGGTGGCCGCGCGCGAGGCGTCCATCTACACGGGCTGCGCCATCGCCGAGTACTTCCGCGACATGGGCCGATCGGTGGCG
CTCATGATCGACTCCACCTCGCGCTGGGCCGAGGCGCTGCGCGAGATCTCGGCGCGGCTGGAGGAGATGCCGGGCGAGGA
GGGCTACCCGACCTACCTCGCCTCGCGGCTGGCGCGCTTCTACGAGCGCGCGGGCCGGGTCGAGACGCTGGGCGGGGCCG
AGGGCGCGGTGACCATGGTGGGCGCGGTGTCGCCGCCCGGCGGCGACCTCTCGGAGCCGGTCACCCAGTGCTCGCTCCGC
GCCACCGGCGCGCTCTGGGCGCTCTCGGCCGACCTGGCGCACCGCCGCCACTACCCGGCGGTGGACTGGAGCGTGTCCTT
CACGCTGGAGGGCGACCGGCTCGCGGGCTGGTTCGAGCGCGAGGCGGGCGACGGGTTCGGCGCGCTGCGCGACGAGGCGC
GCAAGCTCCTGCAGCGAGAGCGCGAGCTGGCCGAGGTGGCCGAGCTCGTGGGGACCGAGTCGCTGCAGGACGCCGAGCGG
CTGGTGCTGGAGTCGGCGCGGCTGCTGCGCGAGGGCTTCCTGCGCCAGAGCGCGCTCGATCCGGCGGACGCGACCTGTCC
GCCCGCGAAGGCGTTCGAGATGCTCCGGCTGTTCCTCGAGTGGCACCGGCGCGCCGGCGCCGCGGTCGGCGCGGGCGTGC
CGCTCCGGTCGATCCTCGACACCGGCCTGGGTGCGCGCCTGCTCCGGCTGGCGCAGCTCCCGGCCGCCGAGGTGCCCGGG
GCGGCGGCCGCGCTGCGCGCGGATCTCTCGGAGGCGCTGGCGCGCCTGGAGGCGGAGTGA

Upstream 100 bases:

>100_bases
TGGGCGAGGAGGGCAGGGGGCGCGCCTACGTCGCGGCGCTCATCCGCCGCGCCGTGGGCTACGGGGTCAAGCTGGGCAGC
GCGGGCGGGGGAGGGGCGAC

Downstream 100 bases:

>100_bases
TCATGGACCTCGTCACCCGCCGGATCCGCGGGGCGCTCGGCATCGCCGGCCCGCTGCTGTTCCTGGAGGGCGTGCCGCGC
GCGCGCCTGGGCGAGGTGGT

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSGTLMRMAGPTVVAEGLSGASLNEVVRVGEERLLGEIIRIEGDRATIQVYEETAGLALGEPVEASGEPLAVELGPGLLG
SVFDGVQRPLSELAAREGDFLGRGASLPALDRTRAWEFEPAVAPGDRVEGGARLGVARAPGAPDHPVVVPPGVTGRVAEV
RGGARRVDEPAVLLEGGATLALLERWPVRRPRPARRRLPPDVPFLTGQRVLDCFFPVSAGGTAVVPGGFGTGKTVLEQSL
AKWAAADVVVYVGCGERGNEMSEVLDEFPRLEDPRTGGPLLARTVMIVNTSNMPVAAREASIYTGCAIAEYFRDMGRSVA
LMIDSTSRWAEALREISARLEEMPGEEGYPTYLASRLARFYERAGRVETLGGAEGAVTMVGAVSPPGGDLSEPVTQCSLR
ATGALWALSADLAHRRHYPAVDWSVSFTLEGDRLAGWFEREAGDGFGALRDEARKLLQRERELAEVAELVGTESLQDAER
LVLESARLLREGFLRQSALDPADATCPPAKAFEMLRLFLEWHRRAGAAVGAGVPLRSILDTGLGARLLRLAQLPAAEVPG
AAAALRADLSEALARLEAE

Sequences:

>Translated_579_residues
MSGTLMRMAGPTVVAEGLSGASLNEVVRVGEERLLGEIIRIEGDRATIQVYEETAGLALGEPVEASGEPLAVELGPGLLG
SVFDGVQRPLSELAAREGDFLGRGASLPALDRTRAWEFEPAVAPGDRVEGGARLGVARAPGAPDHPVVVPPGVTGRVAEV
RGGARRVDEPAVLLEGGATLALLERWPVRRPRPARRRLPPDVPFLTGQRVLDCFFPVSAGGTAVVPGGFGTGKTVLEQSL
AKWAAADVVVYVGCGERGNEMSEVLDEFPRLEDPRTGGPLLARTVMIVNTSNMPVAAREASIYTGCAIAEYFRDMGRSVA
LMIDSTSRWAEALREISARLEEMPGEEGYPTYLASRLARFYERAGRVETLGGAEGAVTMVGAVSPPGGDLSEPVTQCSLR
ATGALWALSADLAHRRHYPAVDWSVSFTLEGDRLAGWFEREAGDGFGALRDEARKLLQRERELAEVAELVGTESLQDAER
LVLESARLLREGFLRQSALDPADATCPPAKAFEMLRLFLEWHRRAGAAVGAGVPLRSILDTGLGARLLRLAQLPAAEVPG
AAAALRADLSEALARLEAE
>Mature_578_residues
SGTLMRMAGPTVVAEGLSGASLNEVVRVGEERLLGEIIRIEGDRATIQVYEETAGLALGEPVEASGEPLAVELGPGLLGS
VFDGVQRPLSELAAREGDFLGRGASLPALDRTRAWEFEPAVAPGDRVEGGARLGVARAPGAPDHPVVVPPGVTGRVAEVR
GGARRVDEPAVLLEGGATLALLERWPVRRPRPARRRLPPDVPFLTGQRVLDCFFPVSAGGTAVVPGGFGTGKTVLEQSLA
KWAAADVVVYVGCGERGNEMSEVLDEFPRLEDPRTGGPLLARTVMIVNTSNMPVAAREASIYTGCAIAEYFRDMGRSVAL
MIDSTSRWAEALREISARLEEMPGEEGYPTYLASRLARFYERAGRVETLGGAEGAVTMVGAVSPPGGDLSEPVTQCSLRA
TGALWALSADLAHRRHYPAVDWSVSFTLEGDRLAGWFEREAGDGFGALRDEARKLLQRERELAEVAELVGTESLQDAERL
VLESARLLREGFLRQSALDPADATCPPAKAFEMLRLFLEWHRRAGAAVGAGVPLRSILDTGLGARLLRLAQLPAAEVPGA
AAALRADLSEALARLEAE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI19913424, Length=599, Percent_Identity=44.7412353923205, Blast_Score=513, Evalue=1e-145,
Organism=Homo sapiens, GI32189394, Length=303, Percent_Identity=29.3729372937294, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913426, Length=241, Percent_Identity=25.3112033195021, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI19913428, Length=241, Percent_Identity=24.896265560166, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI50345984, Length=240, Percent_Identity=25.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4757810, Length=240, Percent_Identity=25.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1790170, Length=376, Percent_Identity=30.3191489361702, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790172, Length=320, Percent_Identity=28.125, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788251, Length=309, Percent_Identity=28.8025889967638, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565854, Length=593, Percent_Identity=44.5193929173693, Blast_Score=506, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI25144756, Length=303, Percent_Identity=29.3729372937294, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=241, Percent_Identity=27.3858921161826, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=440, Percent_Identity=25.4545454545455, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988080, Length=246, Percent_Identity=27.2357723577236, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71988074, Length=246, Percent_Identity=27.2357723577236, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17570191, Length=241, Percent_Identity=24.896265560166, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320016, Length=314, Percent_Identity=45.859872611465, Blast_Score=294, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6322581, Length=295, Percent_Identity=30.8474576271186, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319603, Length=241, Percent_Identity=27.3858921161826, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319370, Length=305, Percent_Identity=24.2622950819672, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583988, Length=598, Percent_Identity=44.1471571906354, Blast_Score=523, Evalue=1e-148,
Organism=Drosophila melanogaster, GI24583986, Length=598, Percent_Identity=44.1471571906354, Blast_Score=523, Evalue=1e-148,
Organism=Drosophila melanogaster, GI24583984, Length=598, Percent_Identity=44.1471571906354, Blast_Score=523, Evalue=1e-148,
Organism=Drosophila melanogaster, GI20129479, Length=538, Percent_Identity=48.6988847583643, Blast_Score=514, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24583992, Length=537, Percent_Identity=47.8584729981378, Blast_Score=513, Evalue=1e-145,
Organism=Drosophila melanogaster, GI28574560, Length=304, Percent_Identity=31.25, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24638766, Length=303, Percent_Identity=29.3729372937294, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281361666, Length=255, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646341, Length=255, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17136796, Length=255, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24658560, Length=295, Percent_Identity=26.7796610169492, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): VATA_ANAD2 (B8JE35)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002493166.1
- ProteinModelPortal:   B8JE35
- SMR:   B8JE35
- GeneID:   7298831
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_2763
- HOGENOM:   HBG288114
- ProtClustDB:   PRK04192
- HAMAP:   MF_00309
- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 61609; Mature: 61478

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTLMRMAGPTVVAEGLSGASLNEVVRVGEERLLGEIIRIEGDRATIQVYEETAGLALG
CCCCEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEEHHCCCCCC
EPVEASGEPLAVELGPGLLGSVFDGVQRPLSELAAREGDFLGRGASLPALDRTRAWEFEP
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AVAPGDRVEGGARLGVARAPGAPDHPVVVPPGVTGRVAEVRGGARRVDEPAVLLEGGATL
CCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCEEEECCCEE
ALLERWPVRRPRPARRRLPPDVPFLTGQRVLDCFFPVSAGGTAVVPGGFGTGKTVLEQSL
EHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHH
AKWAAADVVVYVGCGERGNEMSEVLDEFPRLEDPRTGGPLLARTVMIVNTSNMPVAAREA
HHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCHHHEEEEEEECCCCCCEECCC
SIYTGCAIAEYFRDMGRSVALMIDSTSRWAEALREISARLEEMPGEEGYPTYLASRLARF
HHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YERAGRVETLGGAEGAVTMVGAVSPPGGDLSEPVTQCSLRATGALWALSADLAHRRHYPA
HHHCCCEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
VDWSVSFTLEGDRLAGWFEREAGDGFGALRDEARKLLQRERELAEVAELVGTESLQDAER
CCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVLESARLLREGFLRQSALDPADATCPPAKAFEMLRLFLEWHRRAGAAVGAGVPLRSILD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
TGLGARLLRLAQLPAAEVPGAAAALRADLSEALARLEAE
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGTLMRMAGPTVVAEGLSGASLNEVVRVGEERLLGEIIRIEGDRATIQVYEETAGLALG
CCCEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEEHHCCCCCC
EPVEASGEPLAVELGPGLLGSVFDGVQRPLSELAAREGDFLGRGASLPALDRTRAWEFEP
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AVAPGDRVEGGARLGVARAPGAPDHPVVVPPGVTGRVAEVRGGARRVDEPAVLLEGGATL
CCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCEEEECCCEE
ALLERWPVRRPRPARRRLPPDVPFLTGQRVLDCFFPVSAGGTAVVPGGFGTGKTVLEQSL
EHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHH
AKWAAADVVVYVGCGERGNEMSEVLDEFPRLEDPRTGGPLLARTVMIVNTSNMPVAAREA
HHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCHHHEEEEEEECCCCCCEECCC
SIYTGCAIAEYFRDMGRSVALMIDSTSRWAEALREISARLEEMPGEEGYPTYLASRLARF
HHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YERAGRVETLGGAEGAVTMVGAVSPPGGDLSEPVTQCSLRATGALWALSADLAHRRHYPA
HHHCCCEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
VDWSVSFTLEGDRLAGWFEREAGDGFGALRDEARKLLQRERELAEVAELVGTESLQDAER
CCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVLESARLLREGFLRQSALDPADATCPPAKAFEMLRLFLEWHRRAGAAVGAGVPLRSILD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
TGLGARLLRLAQLPAAEVPGAAAALRADLSEALARLEAE
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA