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The map label for this gene is sigC [H]

Identifier: 220917834

GI number: 220917834

Start: 3017295

End: 3018263

Strand: Direct

Name: sigC [H]

Synonym: A2cp1_2735

Alternate gene names: 220917834

Gene position: 3017295-3018263 (Clockwise)

Preceding gene: 220917831

Following gene: 220917837

Centisome position: 59.99

GC content: 70.9

Gene sequence:

>969_bases
ATGTCGGACGAGACGCGTCACCGCTCCACGAAGGGCCGCCCCGCACTCCCGTCCGCCGGGGAGGCGCGCGACCGCTCCGA
GGGCGGGCTGGTCCGCTACGACCCGCTCCGCGCGTACATGGCCGAGGTGGCGCGCCACCCGGTGCTCTCGCGGGACGAGG
AGCACGCGCTCGCGGTCCAGTACCGCGAGACCGGCGACGTGGACGCCGCGTACCGGCTGGTCGCGTCCAATCTGCGACTG
GTGGTGAAGATCGCCCACGAGTACCGCCGCACCGCGTTCCAGCTCCTGGATCTCGTCCAGGAAGGCAACCTCGGGCTCAT
GCAGGCGGTGAAGAAGTACGATCCGTGGAAGGGCGTGAAGCTCTCGTCCTACGCGGCCTGGTGGATCCGCGCGTACATCA
TCCGCTTCATCATGGAGAACTGGCGGCTGGTGAAGCTCGGGACCACCCAGGCGCAGCGCAAGCTGTTCTTCAACCTCTCC
AAGGAGCGCGAGAAGCTGCTCGCGCGCGGCATCGAACCGACGCCGCGGCTGCTCGCGAAGAACCTCCAGGTCGAGGAGAA
GGACGTGGAGGAGATGAGCGCGCGCATGGCCGCGGACGACCTCTCGCTGGACGCGCCGGTCGGCACCGAGGGCGACGACG
GCCGCCAGAACCGCCTCGACCGGCTGGCCGACGACGGCGGCCCGTCGCCCGACGCCGCGCTCGGCGACGAGCAGCTCCGG
CGGATCTTCCGCGAGAAGCTGGACGCGTTCTCCGGGACGCTCACCGACGAGAAGGAGCGGTACATCTTCGAGCACCGCCT
CCTCCCGCCCGACGGCACGCCGCCGCTCACGCTGCAGGAGGTGGGCGACCACTTCCGCCTCACCCGCGAGCGCGCCCGCC
AGATCGAGGCCAAGCTGACCGGGCGGCTGCGCGAGTTCCTCCGCGCCGAGATCCCGGACTTCGAGCTGCTCGGGCCGCCC
GAGACCTGA

Upstream 100 bases:

>100_bases
ATGCGCCGACGTGTCGTCTCGCGCCTTGCGCGCGAGGCGCGACACCTATATCACAACGCACTTGCGCGGCCGCCAGTTCC
CGTGGCAGCCCGGACTCCCC

Downstream 100 bases:

>100_bases
GGCACGTGCACCGCCCGGACCGCGCCCCTGCGCGCCGCCGGGCGGCGCGCGAGTCGCGCTAGTCGCGCAGCGCGCCCGGC
CCCGGACGCGCCGCGGCCGC

Product: RNA polymerase sigma-32 subunit RpoH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSDETRHRSTKGRPALPSAGEARDRSEGGLVRYDPLRAYMAEVARHPVLSRDEEHALAVQYRETGDVDAAYRLVASNLRL
VVKIAHEYRRTAFQLLDLVQEGNLGLMQAVKKYDPWKGVKLSSYAAWWIRAYIIRFIMENWRLVKLGTTQAQRKLFFNLS
KEREKLLARGIEPTPRLLAKNLQVEEKDVEEMSARMAADDLSLDAPVGTEGDDGRQNRLDRLADDGGPSPDAALGDEQLR
RIFREKLDAFSGTLTDEKERYIFEHRLLPPDGTPPLTLQEVGDHFRLTRERARQIEAKLTGRLREFLRAEIPDFELLGPP
ET

Sequences:

>Translated_322_residues
MSDETRHRSTKGRPALPSAGEARDRSEGGLVRYDPLRAYMAEVARHPVLSRDEEHALAVQYRETGDVDAAYRLVASNLRL
VVKIAHEYRRTAFQLLDLVQEGNLGLMQAVKKYDPWKGVKLSSYAAWWIRAYIIRFIMENWRLVKLGTTQAQRKLFFNLS
KEREKLLARGIEPTPRLLAKNLQVEEKDVEEMSARMAADDLSLDAPVGTEGDDGRQNRLDRLADDGGPSPDAALGDEQLR
RIFREKLDAFSGTLTDEKERYIFEHRLLPPDGTPPLTLQEVGDHFRLTRERARQIEAKLTGRLREFLRAEIPDFELLGPP
ET
>Mature_321_residues
SDETRHRSTKGRPALPSAGEARDRSEGGLVRYDPLRAYMAEVARHPVLSRDEEHALAVQYRETGDVDAAYRLVASNLRLV
VKIAHEYRRTAFQLLDLVQEGNLGLMQAVKKYDPWKGVKLSSYAAWWIRAYIIRFIMENWRLVKLGTTQAQRKLFFNLSK
EREKLLARGIEPTPRLLAKNLQVEEKDVEEMSARMAADDLSLDAPVGTEGDDGRQNRLDRLADDGGPSPDAALGDEQLRR
IFREKLDAFSGTLTDEKERYIFEHRLLPPDGTPPLTLQEVGDHFRLTRERARQIEAKLTGRLREFLRAEIPDFELLGPPE
T

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is essential for normal fruiting body formation [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789871, Length=274, Percent_Identity=37.956204379562, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789098, Length=295, Percent_Identity=35.5932203389831, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789448, Length=243, Percent_Identity=34.5679012345679, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 36803; Mature: 36672

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00715 SIGMA70_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDETRHRSTKGRPALPSAGEARDRSEGGLVRYDPLRAYMAEVARHPVLSRDEEHALAVQ
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEE
YRETGDVDAAYRLVASNLRLVVKIAHEYRRTAFQLLDLVQEGNLGLMQAVKKYDPWKGVK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
LSSYAAWWIRAYIIRFIMENWRLVKLGTTQAQRKLFFNLSKEREKLLARGIEPTPRLLAK
HHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
NLQVEEKDVEEMSARMAADDLSLDAPVGTEGDDGRQNRLDRLADDGGPSPDAALGDEQLR
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
RIFREKLDAFSGTLTDEKERYIFEHRLLPPDGTPPLTLQEVGDHFRLTRERARQIEAKLT
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
GRLREFLRAEIPDFELLGPPET
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDETRHRSTKGRPALPSAGEARDRSEGGLVRYDPLRAYMAEVARHPVLSRDEEHALAVQ
CCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEE
YRETGDVDAAYRLVASNLRLVVKIAHEYRRTAFQLLDLVQEGNLGLMQAVKKYDPWKGVK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
LSSYAAWWIRAYIIRFIMENWRLVKLGTTQAQRKLFFNLSKEREKLLARGIEPTPRLLAK
HHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
NLQVEEKDVEEMSARMAADDLSLDAPVGTEGDDGRQNRLDRLADDGGPSPDAALGDEQLR
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
RIFREKLDAFSGTLTDEKERYIFEHRLLPPDGTPPLTLQEVGDHFRLTRERARQIEAKLT
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
GRLREFLRAEIPDFELLGPPET
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501037 [H]