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The map label for this gene is scrK [H]

Identifier: 220917751

GI number: 220917751

Start: 2930803

End: 2931753

Strand: Reverse

Name: scrK [H]

Synonym: A2cp1_2652

Alternate gene names: 220917751

Gene position: 2931753-2930803 (Counterclockwise)

Preceding gene: 220917752

Following gene: 220917750

Centisome position: 58.29

GC content: 78.23

Gene sequence:

>951_bases
ATGAGGGATCTCGACGTGCTGTGCCTGGGGGAGGCGCTGGTGGACCTGCTGCCGGATCGGCGTGGGGCCCTGGAGGACTG
CGGCCGCTTCGAGGCGTGCCCCGGCGGCGCGCCGGCGAACGTCGCCACCGGGCTGGCGCGCCTCGGGGTCCGCACCGGCT
TCCGCGGCGTGGTCGGCGACGATCCGTTCGGCCGGATGCTGGCGCGCCGGCTCGCCGCCGAGGGCATCGAGGTCTCGCTC
CGGCTCGCGCGCGAGCGGCCCACCGGGATGTGGTTCGTGGCGCTCGACGCGGCGGGGGAGCGGACGTTCTTCTCGCCCAA
CGCCCGCTTCTCCGCCGACAAGCTCGTCGCGCCCGCCGACGCCGACCCGGCCGCGATCGGCCGCGCCCGCGTGCTGCACA
CCGGGACCTCGGCGCACGTGCTGCCGGAGGGCAGGGCGGCGCTGCGGGCCGCGGTGGAGGCGGCGCGGCGCCTCGGCGTG
GAGGTGTCCTTCGACCCGAACGTCCGCGCGCACCTGTGGGACGACCTCGCGCCGCTGCGGGCGCTCTGCCAGGACGTGCT
GCCGCGCTGCGCGGTGGCGAAGCTCTCCGAGGAGGAGATCGCGCTCTGCACCGGCGAGGCCGACCCCGCGCGCGCTGCGG
CGCGGCTCGTCGCGATGGGCGTCGGCATCGCCTGCGTGACGCTGGGCCCGCGCGGCGCCCTGGTACGGCGCGGCGCCGAC
GAGGCGCACGTGCCGGCCGAGCCGGTGGCGGTGGTGGACACCACCGGCGCCGGCGACGGGTTCGTGGCCGGGCTGCTCGC
GGCGCTCTCGCGCGGCGCGGCCCCGCTCGCCGCCCGCTCGTTCGCCGAGGTGGTCGCGGCGGTGCGCTTCGCGAACCGGG
TGGCGGGGCGCGTCTGCACGCGCGTCGGCGCGGTCGCCGGGCTGCCGCACACTGGCGAGATTTCCGTTTGA

Upstream 100 bases:

>100_bases
CGACGAGATCGGGCCGCTGCTGGGCGCCTGACGTGACGTCGGCCCGCGCCGGCCCGCCATCGCATCCGCTCGACCGCGCC
ACGCCCGGAGGCAGGCCGCC

Downstream 100 bases:

>100_bases
CACCCGCACCTTACGGCCCTACGGTGCCCGTTCCCCGGCCCGTTCGCCGCGGCGCGGCCGCCCCGCCGGATGATCCGCGG
GCGCGCGCCGGCTCGAACGC

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRDLDVLCLGEALVDLLPDRRGALEDCGRFEACPGGAPANVATGLARLGVRTGFRGVVGDDPFGRMLARRLAAEGIEVSL
RLARERPTGMWFVALDAAGERTFFSPNARFSADKLVAPADADPAAIGRARVLHTGTSAHVLPEGRAALRAAVEAARRLGV
EVSFDPNVRAHLWDDLAPLRALCQDVLPRCAVAKLSEEEIALCTGEADPARAAARLVAMGVGIACVTLGPRGALVRRGAD
EAHVPAEPVAVVDTTGAGDGFVAGLLAALSRGAAPLAARSFAEVVAAVRFANRVAGRVCTRVGAVAGLPHTGEISV

Sequences:

>Translated_316_residues
MRDLDVLCLGEALVDLLPDRRGALEDCGRFEACPGGAPANVATGLARLGVRTGFRGVVGDDPFGRMLARRLAAEGIEVSL
RLARERPTGMWFVALDAAGERTFFSPNARFSADKLVAPADADPAAIGRARVLHTGTSAHVLPEGRAALRAAVEAARRLGV
EVSFDPNVRAHLWDDLAPLRALCQDVLPRCAVAKLSEEEIALCTGEADPARAAARLVAMGVGIACVTLGPRGALVRRGAD
EAHVPAEPVAVVDTTGAGDGFVAGLLAALSRGAAPLAARSFAEVVAAVRFANRVAGRVCTRVGAVAGLPHTGEISV
>Mature_316_residues
MRDLDVLCLGEALVDLLPDRRGALEDCGRFEACPGGAPANVATGLARLGVRTGFRGVVGDDPFGRMLARRLAAEGIEVSL
RLARERPTGMWFVALDAAGERTFFSPNARFSADKLVAPADADPAAIGRARVLHTGTSAHVLPEGRAALRAAVEAARRLGV
EVSFDPNVRAHLWDDLAPLRALCQDVLPRCAVAKLSEEEIALCTGEADPARAAARLVAMGVGIACVTLGPRGALVRRGAD
EAHVPAEPVAVVDTTGAGDGFVAGLLAALSRGAAPLAARSFAEVVAAVRFANRVAGRVCTRVGAVAGLPHTGEISV

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=238, Percent_Identity=30.672268907563, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081971, Length=321, Percent_Identity=28.9719626168224, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789775, Length=268, Percent_Identity=28.7313432835821, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87082343, Length=314, Percent_Identity=28.9808917197452, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082281, Length=259, Percent_Identity=27.7992277992278, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790193, Length=248, Percent_Identity=25.4032258064516, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 32682; Mature: 32682

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLDVLCLGEALVDLLPDRRGALEDCGRFEACPGGAPANVATGLARLGVRTGFRGVVGD
CCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
DPFGRMLARRLAAEGIEVSLRLARERPTGMWFVALDAAGERTFFSPNARFSADKLVAPAD
CHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCEECCCC
ADPAAIGRARVLHTGTSAHVLPEGRAALRAAVEAARRLGVEVSFDPNVRAHLWDDLAPLR
CCHHHHCCEEEEECCCCCEECCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
ALCQDVLPRCAVAKLSEEEIALCTGEADPARAAARLVAMGVGIACVTLGPRGALVRRGAD
HHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHCCCC
EAHVPAEPVAVVDTTGAGDGFVAGLLAALSRGAAPLAARSFAEVVAAVRFANRVAGRVCT
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGAVAGLPHTGEISV
HHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRDLDVLCLGEALVDLLPDRRGALEDCGRFEACPGGAPANVATGLARLGVRTGFRGVVGD
CCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
DPFGRMLARRLAAEGIEVSLRLARERPTGMWFVALDAAGERTFFSPNARFSADKLVAPAD
CHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCEECCCC
ADPAAIGRARVLHTGTSAHVLPEGRAALRAAVEAARRLGVEVSFDPNVRAHLWDDLAPLR
CCHHHHCCEEEEECCCCCEECCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
ALCQDVLPRCAVAKLSEEEIALCTGEADPARAAARLVAMGVGIACVTLGPRGALVRRGAD
HHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHCCCC
EAHVPAEPVAVVDTTGAGDGFVAGLLAALSRGAAPLAARSFAEVVAAVRFANRVAGRVCT
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGAVAGLPHTGEISV
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1809835 [H]