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The map label for this gene is cheA [H]

Identifier: 220917682

GI number: 220917682

Start: 2862486

End: 2864621

Strand: Reverse

Name: cheA [H]

Synonym: A2cp1_2583

Alternate gene names: 220917682

Gene position: 2864621-2862486 (Counterclockwise)

Preceding gene: 220917699

Following gene: 220917681

Centisome position: 56.96

GC content: 76.45

Gene sequence:

>2136_bases
ATGTCCGGAGGACCAGGGGACGACGCGCGCGAGGCGCTGGCGGCCGCGGTGGTGGCGGCGGATGCGGCCGACCCGGCGTC
GCTCTGCGAGGTCTCGCGGGCGCTGGCCGCGGCCACCGCCGCGGGTGCGCTCGACGGCGCGCTCGCCGCGGAGGCCGGCG
CGCTGGGCCGCGCGCTGGACGGGAGCGACGGCGACGACGCCGGCGGGGCCGCGGCGGCGCTGGCCCGCCTCTCGGCGCTG
CTCGGCGGCGGCGAGCTGGAGCGGCCCGCCGCGGCGGAGGCGCTGCCGCCGGCGGCGCGGGCCAGCCGCGACGCGGACAC
GCTCGAGCTCATCGGCGACTTCCTGGAGGAGGGGCTCGACGGCCTGGCCCGCGCGGACGAGACGCTCCTCGCGGTGGAGC
GAGACGGGCCGCACCCGGACCGCACCAACGCGCTGTTCCGCGTCTTCCACACCATCAAGGGCGTGGCCGGGTTCCTGGAG
CTCGGCGAGATCGTCTCGCTCGCGCACACGGCCGAGACGCTGCTCGACCACGTGCGCAGCGGCCGCGCGGCGCTGGCCGG
CGAGGCCTTCGACGTGACGTTCGAGGCGACCGCAGCGCTCCGGAGCCTGCTGGAGCGGCTGCGTGAGGCGGTGGACGCGC
GCGCGGACCTCCTGCCGGACGCGCGCGTGCCGGGGCTGGTGGCGCGGATCGCGGCGGTGAGCGCGGCCGCCGAGGCGGCG
CCCGAGGCGGCGGGCGAGGGGACGGCGCCGGCCATGCCGCTTGCCACGGACCTGGCCGCGACCCCCGTCGCCACCGCGGC
TCCGACCGCAGCGATCCCCCCGCCTCGGCCCGCGCCCGCGCCGCCGAGGCCAGCGCCCGCCGTGGAGCCGGAGGCGGCGG
CCGAGCCCGCGTCGGCCGCGCCCGCGCCGCCGCCCCACGGCGGCGGTCAGCTCCGCGAGACGGTGAAGGTGGATCTCGAG
CGGGTGGACTCGATGGTGGAGATGATCGGCGAGCTCATCATCGTCGAGTCGATGGTGGTGCACGCGCCGGAGCTGGCGGC
GGTGGCCTCCCTGCGCCTGCGCAACTCGCTCAACCAGATGACCAAGATCAGCCGCGACCTGCAGAACGTGGCCATGCGGA
TGCGCATGGTCCCGGTGCGCGGCGCGTTCCAGAAGATGGCGCGCCTGGTCCGGGATCTCTCGCGCAGGACCGGCAAGGAC
GTGGTCCTCGAGACCTCCGGCGAGGACACCGAGATGGACCGCAGCATGGTCGAGCGCATCGAGGACCCGCTCGTGCACCT
GGTGCGGAACGCGCTCGACCACGGCATCGAGCCGGAGGCGGAGCGCCTCGCCGCGGGGAAGGCCGCGCGGTCCGTCCTGC
GGCTGGCCGCCTACCACGAGGGCGGGTCGATCGTGGTGGAGCTGGCCGACGACGGGCGGGGGCTGCAGCGCGACCGGATC
CTGCGCAAGGCGCGCGAGCGTGGGCTGGTGGGCGACGGGCAGGAGCTGTCCGACGCCGAGGTCCACGGGCTGGTGTTCCT
GCCCGGCTTCTCCACCGCGGCCAAGGTCACCGAGATCTCCGGGCGCGGCGTGGGCATGGACGTGGTGAAGCGCAACGTCG
AGGGGATGCGCGGCCGCGTCACCGTGGCCTCGCGCGCGGGCGGGGGGACCACGTTCCGGCTGGTGCTCCCGCTCACCCTC
GCCATCATCGACGGCATGCTCGTCTCCTGCGGAGGCGAGACCTACATCCTGCCCAGCCTCTCGATCGTCGAGTCGCTGCG
GCCGGCCGATGACACGATCCGGCGCGCCGCGGGACGCGGCGAGGTGATCGACGTCCGCGGCGAGATCCTGCCGCTCCTGC
GCCTGCACCGGCTGCTCGGCGCGCGCGAGCGCGCCGCGGGCGCAGACGACCTGCGGGTGGTCGTGGTCGAGGGGCTGGGT
CGCAAGGTGGGGCTGGTGGTGGACGACGTGGTCACCCAGCAGCAGGTGGTGATCAAGCCCCTGGGGAGCGGCCTCGGCGA
CACGGACTTCCTCTCCGGCGCGGCGATCCTCTCCGACGGCCGGGTGGGGTTGATCCTGAACGTGGACCGGCTGGCAGGGC
TCGCGTCGCGCGACGCGGCGGCGGACCGCGGCGCCCGGCTGGCGGCGGGGGCCTAG

Upstream 100 bases:

>100_bases
CCCGGGCGCGGCGTCCCGGGATCCGGGCACGCGCGCTGCAACGGCGTGCGGGTCGACCGGCACGGCCAGGACGCGGCGCC
GGGAGCGATCGGAGGACGGG

Downstream 100 bases:

>100_bases
GGTGGACGCGGAGACGTACCAGGGCTTCCAGCGCATCGCCCACGAGCGGGCCGGGATCTTCCTGCGCCCGGGCAAGGCGG
CCCTGGTGGAGGCGCGGCTC

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MSGGPGDDAREALAAAVVAADAADPASLCEVSRALAAATAAGALDGALAAEAGALGRALDGSDGDDAGGAAAALARLSAL
LGGGELERPAAAEALPPAARASRDADTLELIGDFLEEGLDGLARADETLLAVERDGPHPDRTNALFRVFHTIKGVAGFLE
LGEIVSLAHTAETLLDHVRSGRAALAGEAFDVTFEATAALRSLLERLREAVDARADLLPDARVPGLVARIAAVSAAAEAA
PEAAGEGTAPAMPLATDLAATPVATAAPTAAIPPPRPAPAPPRPAPAVEPEAAAEPASAAPAPPPHGGGQLRETVKVDLE
RVDSMVEMIGELIIVESMVVHAPELAAVASLRLRNSLNQMTKISRDLQNVAMRMRMVPVRGAFQKMARLVRDLSRRTGKD
VVLETSGEDTEMDRSMVERIEDPLVHLVRNALDHGIEPEAERLAAGKAARSVLRLAAYHEGGSIVVELADDGRGLQRDRI
LRKARERGLVGDGQELSDAEVHGLVFLPGFSTAAKVTEISGRGVGMDVVKRNVEGMRGRVTVASRAGGGTTFRLVLPLTL
AIIDGMLVSCGGETYILPSLSIVESLRPADDTIRRAAGRGEVIDVRGEILPLLRLHRLLGARERAAGADDLRVVVVEGLG
RKVGLVVDDVVTQQQVVIKPLGSGLGDTDFLSGAAILSDGRVGLILNVDRLAGLASRDAAADRGARLAAGA

Sequences:

>Translated_711_residues
MSGGPGDDAREALAAAVVAADAADPASLCEVSRALAAATAAGALDGALAAEAGALGRALDGSDGDDAGGAAAALARLSAL
LGGGELERPAAAEALPPAARASRDADTLELIGDFLEEGLDGLARADETLLAVERDGPHPDRTNALFRVFHTIKGVAGFLE
LGEIVSLAHTAETLLDHVRSGRAALAGEAFDVTFEATAALRSLLERLREAVDARADLLPDARVPGLVARIAAVSAAAEAA
PEAAGEGTAPAMPLATDLAATPVATAAPTAAIPPPRPAPAPPRPAPAVEPEAAAEPASAAPAPPPHGGGQLRETVKVDLE
RVDSMVEMIGELIIVESMVVHAPELAAVASLRLRNSLNQMTKISRDLQNVAMRMRMVPVRGAFQKMARLVRDLSRRTGKD
VVLETSGEDTEMDRSMVERIEDPLVHLVRNALDHGIEPEAERLAAGKAARSVLRLAAYHEGGSIVVELADDGRGLQRDRI
LRKARERGLVGDGQELSDAEVHGLVFLPGFSTAAKVTEISGRGVGMDVVKRNVEGMRGRVTVASRAGGGTTFRLVLPLTL
AIIDGMLVSCGGETYILPSLSIVESLRPADDTIRRAAGRGEVIDVRGEILPLLRLHRLLGARERAAGADDLRVVVVEGLG
RKVGLVVDDVVTQQQVVIKPLGSGLGDTDFLSGAAILSDGRVGLILNVDRLAGLASRDAAADRGARLAAGA
>Mature_710_residues
SGGPGDDAREALAAAVVAADAADPASLCEVSRALAAATAAGALDGALAAEAGALGRALDGSDGDDAGGAAAALARLSALL
GGGELERPAAAEALPPAARASRDADTLELIGDFLEEGLDGLARADETLLAVERDGPHPDRTNALFRVFHTIKGVAGFLEL
GEIVSLAHTAETLLDHVRSGRAALAGEAFDVTFEATAALRSLLERLREAVDARADLLPDARVPGLVARIAAVSAAAEAAP
EAAGEGTAPAMPLATDLAATPVATAAPTAAIPPPRPAPAPPRPAPAVEPEAAAEPASAAPAPPPHGGGQLRETVKVDLER
VDSMVEMIGELIIVESMVVHAPELAAVASLRLRNSLNQMTKISRDLQNVAMRMRMVPVRGAFQKMARLVRDLSRRTGKDV
VLETSGEDTEMDRSMVERIEDPLVHLVRNALDHGIEPEAERLAAGKAARSVLRLAAYHEGGSIVVELADDGRGLQRDRIL
RKARERGLVGDGQELSDAEVHGLVFLPGFSTAAKVTEISGRGVGMDVVKRNVEGMRGRVTVASRAGGGTTFRLVLPLTLA
IIDGMLVSCGGETYILPSLSIVESLRPADDTIRRAAGRGEVIDVRGEILPLLRLHRLLGARERAAGADDLRVVVVEGLGR
KVGLVVDDVVTQQQVVIKPLGSGLGDTDFLSGAAILSDGRVGLILNVDRLAGLASRDAAADRGARLAAGA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=440, Percent_Identity=42.0454545454545, Blast_Score=325, Evalue=5e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73420; Mature: 73288

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGPGDDAREALAAAVVAADAADPASLCEVSRALAAATAAGALDGALAAEAGALGRALD
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSDGDDAGGAAAALARLSALLGGGELERPAAAEALPPAARASRDADTLELIGDFLEEGLD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
GLARADETLLAVERDGPHPDRTNALFRVFHTIKGVAGFLELGEIVSLAHTAETLLDHVRS
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRAALAGEAFDVTFEATAALRSLLERLREAVDARADLLPDARVPGLVARIAAVSAAAEAA
CCHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
PEAAGEGTAPAMPLATDLAATPVATAAPTAAIPPPRPAPAPPRPAPAVEPEAAAEPASAA
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCC
PAPPPHGGGQLRETVKVDLERVDSMVEMIGELIIVESMVVHAPELAAVASLRLRNSLNQM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TKISRDLQNVAMRMRMVPVRGAFQKMARLVRDLSRRTGKDVVLETSGEDTEMDRSMVERI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
EDPLVHLVRNALDHGIEPEAERLAAGKAARSVLRLAAYHEGGSIVVELADDGRGLQRDRI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
LRKARERGLVGDGQELSDAEVHGLVFLPGFSTAAKVTEISGRGVGMDVVKRNVEGMRGRV
HHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCEE
TVASRAGGGTTFRLVLPLTLAIIDGMLVSCGGETYILPSLSIVESLRPADDTIRRAAGRG
EEEECCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCHHHHHHHCCCC
EVIDVRGEILPLLRLHRLLGARERAAGADDLRVVVVEGLGRKVGLVVDDVVTQQQVVIKP
CEEECCHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCHHCHHHHHHHHHHHHHHHH
LGSGLGDTDFLSGAAILSDGRVGLILNVDRLAGLASRDAAADRGARLAAGA
HCCCCCCHHHHCCHHEECCCCEEEEEEHHHHHCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGGPGDDAREALAAAVVAADAADPASLCEVSRALAAATAAGALDGALAAEAGALGRALD
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSDGDDAGGAAAALARLSALLGGGELERPAAAEALPPAARASRDADTLELIGDFLEEGLD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
GLARADETLLAVERDGPHPDRTNALFRVFHTIKGVAGFLELGEIVSLAHTAETLLDHVRS
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRAALAGEAFDVTFEATAALRSLLERLREAVDARADLLPDARVPGLVARIAAVSAAAEAA
CCHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
PEAAGEGTAPAMPLATDLAATPVATAAPTAAIPPPRPAPAPPRPAPAVEPEAAAEPASAA
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCC
PAPPPHGGGQLRETVKVDLERVDSMVEMIGELIIVESMVVHAPELAAVASLRLRNSLNQM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TKISRDLQNVAMRMRMVPVRGAFQKMARLVRDLSRRTGKDVVLETSGEDTEMDRSMVERI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
EDPLVHLVRNALDHGIEPEAERLAAGKAARSVLRLAAYHEGGSIVVELADDGRGLQRDRI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
LRKARERGLVGDGQELSDAEVHGLVFLPGFSTAAKVTEISGRGVGMDVVKRNVEGMRGRV
HHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCEE
TVASRAGGGTTFRLVLPLTLAIIDGMLVSCGGETYILPSLSIVESLRPADDTIRRAAGRG
EEEECCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCHHHHHHHCCCC
EVIDVRGEILPLLRLHRLLGARERAAGADDLRVVVVEGLGRKVGLVVDDVVTQQQVVIKP
CEEECCHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCHHCHHHHHHHHHHHHHHHH
LGSGLGDTDFLSGAAILSDGRVGLILNVDRLAGLASRDAAADRGARLAAGA
HCCCCCCHHHHCCHHEECCCCEEEEEEHHHHHCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]