Click here to switch to the map view.

The map label for this gene is hup2 [H]

Identifier: 220917567

GI number: 220917567

Start: 2725762

End: 2726034

Strand: Reverse

Name: hup2 [H]

Synonym: A2cp1_2467

Alternate gene names: 220917567

Gene position: 2726034-2725762 (Counterclockwise)

Preceding gene: 220917568

Following gene: 220917566

Centisome position: 54.2

GC content: 67.03

Gene sequence:

>273_bases
ATGACCAAGGCAGACCTCATCGAGAAGGTTCAGGCGCTCCACGACGACCTCTCCAAGCGGCAGGTGGCGCTCCTGGTGGA
CTCGGTGTTCGAGCACCTGGCCAAGGGCATCCGCAAGGACAAGCGCTTCACCATGCCGGGCTTCGGGACGTTCGTGGTGA
AGCGCCGGGCCGGCCGGGTGGGCCGCAACCCGCAGACGGGCGCCGAGATCCAGATCGCTCCCACCAAGACCGTCGGCTTC
AAGCCCGCGCCCGAGCTGAAGAAGGCGCTGTAG

Upstream 100 bases:

>100_bases
CGCTGCGCGTCACCGCGCGCGTGTCCTTCCCTTCGCTGGCTTGACGCTCCCGGAAGGGGAGGCTACCTTCGCGCGGTTTC
ACGCGGGGGACGCGCGCTCC

Downstream 100 bases:

>100_bases
GCGAGGCCCCCATGAGCAGCCTCTCCGACTGGCTGAAGGACTTCCGCGTGCTCCACGCGAAGGCGCGCGCCGGCACGCTC
GCCGGGCGCGAGGCCGACGT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 89

Protein sequence:

>90_residues
MTKADLIEKVQALHDDLSKRQVALLVDSVFEHLAKGIRKDKRFTMPGFGTFVVKRRAGRVGRNPQTGAEIQIAPTKTVGF
KPAPELKKAL

Sequences:

>Translated_90_residues
MTKADLIEKVQALHDDLSKRQVALLVDSVFEHLAKGIRKDKRFTMPGFGTFVVKRRAGRVGRNPQTGAEIQIAPTKTVGF
KPAPELKKAL
>Mature_89_residues
TKADLIEKVQALHDDLSKRQVALLVDSVFEHLAKGIRKDKRFTMPGFGTFVVKRRAGRVGRNPQTGAEIQIAPTKTVGFK
PAPELKKAL

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=40, Blast_Score=69, Evalue=6e-14,
Organism=Escherichia coli, GI1787141, Length=87, Percent_Identity=34.4827586206897, Blast_Score=62, Evalue=6e-12,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=38.8888888888889, Blast_Score=59, Evalue=6e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9969; Mature: 9838

Theoretical pI: Translated: 11.17; Mature: 11.17

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKADLIEKVQALHDDLSKRQVALLVDSVFEHLAKGIRKDKRFTMPGFGTFVVKRRAGRV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
GRNPQTGAEIQIAPTKTVGFKPAPELKKAL
CCCCCCCCEEEECCCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
TKADLIEKVQALHDDLSKRQVALLVDSVFEHLAKGIRKDKRFTMPGFGTFVVKRRAGRV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
GRNPQTGAEIQIAPTKTVGFKPAPELKKAL
CCCCCCCCEEEECCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]