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The map label for this gene is pdxJ [H]

Identifier: 220917555

GI number: 220917555

Start: 2712548

End: 2713276

Strand: Reverse

Name: pdxJ [H]

Synonym: A2cp1_2455

Alternate gene names: 220917555

Gene position: 2713276-2712548 (Counterclockwise)

Preceding gene: 220917556

Following gene: 220917554

Centisome position: 53.95

GC content: 71.88

Gene sequence:

>729_bases
ATGCCCGCACGCCTCGGAGTCAACGTCGATCACGTCGCGACCCTGCGCCAGTCGCGCCGCACCCAGTACCCGGACCCGGT
CGCCGCGGCGGTGCTCGCCGAGATGGGCGGCGCCGACCAGATCACCATCCACCTGCGCGAGGACCGCCGGCACATCCAGG
AGCGCGATCTCCAGGTGCTGCGGAAGACCGTCTCGAGCCGGCTCAACCTCGAGATGGCCGCCACGCAGGACATGGTGAAG
ATCGCGTACGGCGTGAAGCCGGACATCGCCACCCTGGTGCCGGAGCGGCGCGAGGAGCTGACCACCGAGGGCGGCCTGGA
CGTGGTGGGCGGTCGCGAGCACGTGCGCAAGGTGGTGAAGACGCTCCGCGACGCCGAGATCGAGGTGTCGCTGTTCATCG
ACCCGGACCTCGACCAGGTGAAGGCGGCCCACCGCGCCGAGGCGGAGGTGGTGGAGCTGCACACCGGGCGCTACTGCGAC
GCGCGGCTCGCGTCGGATCGCCGGCGCGAGCTGTCGCGCGTCATCGACGCGTGCAAGGCAGCCGCGAAGCTCGGGCTGCG
CGTGGCGGCGGGCCACGGGCTCAACTACCAGAACGTGGTGCCGGTGGCCGCGATCCCGGAGATCGAGGAGCTGAACATCG
GCCACTCGATCGTGGCGCGGGCGGTGCTGGTGGGGTTCGAGCGCGCGGTGCGCGAGATGCGCGAGCTGCTGCGCGAGGCG
CGCCCGTAG

Upstream 100 bases:

>100_bases
AGCCGCTCGAGCGGCCCCGGCCGCCGGGCCGGGCGCCCGCGGCGGGGCGAGGGCACGAACCTCGGCGGTGGAGCGGGTTC
CGCGGTAGACTCCCGCCGCC

Downstream 100 bases:

>100_bases
CGCGGCGCCGCCCGGCGAGCGAGGAGCGGGCGTGATCCTGGGGCTCGGCCTGGACGTGGTGGAGGTGGCCCGGATCCAGC
GGATCCTGGCGGGCCCGCCC

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MPARLGVNVDHVATLRQSRRTQYPDPVAAAVLAEMGGADQITIHLREDRRHIQERDLQVLRKTVSSRLNLEMAATQDMVK
IAYGVKPDIATLVPERREELTTEGGLDVVGGREHVRKVVKTLRDAEIEVSLFIDPDLDQVKAAHRAEAEVVELHTGRYCD
ARLASDRRRELSRVIDACKAAAKLGLRVAAGHGLNYQNVVPVAAIPEIEELNIGHSIVARAVLVGFERAVREMRELLREA
RP

Sequences:

>Translated_242_residues
MPARLGVNVDHVATLRQSRRTQYPDPVAAAVLAEMGGADQITIHLREDRRHIQERDLQVLRKTVSSRLNLEMAATQDMVK
IAYGVKPDIATLVPERREELTTEGGLDVVGGREHVRKVVKTLRDAEIEVSLFIDPDLDQVKAAHRAEAEVVELHTGRYCD
ARLASDRRRELSRVIDACKAAAKLGLRVAAGHGLNYQNVVPVAAIPEIEELNIGHSIVARAVLVGFERAVREMRELLREA
RP
>Mature_241_residues
PARLGVNVDHVATLRQSRRTQYPDPVAAAVLAEMGGADQITIHLREDRRHIQERDLQVLRKTVSSRLNLEMAATQDMVKI
AYGVKPDIATLVPERREELTTEGGLDVVGGREHVRKVVKTLRDAEIEVSLFIDPDLDQVKAAHRAEAEVVELHTGRYCDA
RLASDRRRELSRVIDACKAAAKLGLRVAAGHGLNYQNVVPVAAIPEIEELNIGHSIVARAVLVGFERAVREMRELLREAR
P

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=237, Percent_Identity=56.9620253164557, Blast_Score=279, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 26917; Mature: 26786

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARLGVNVDHVATLRQSRRTQYPDPVAAAVLAEMGGADQITIHLREDRRHIQERDLQVL
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
RKTVSSRLNLEMAATQDMVKIAYGVKPDIATLVPERREELTTEGGLDVVGGREHVRKVVK
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHCCCCCEECCCHHHHHHHHH
TLRDAEIEVSLFIDPDLDQVKAAHRAEAEVVELHTGRYCDARLASDRRRELSRVIDACKA
HHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAKLGLRVAAGHGLNYQNVVPVAAIPEIEELNIGHSIVARAVLVGFERAVREMRELLREA
HHHHCCCEECCCCCCCCCCCCHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RP
CC
>Mature Secondary Structure 
PARLGVNVDHVATLRQSRRTQYPDPVAAAVLAEMGGADQITIHLREDRRHIQERDLQVL
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
RKTVSSRLNLEMAATQDMVKIAYGVKPDIATLVPERREELTTEGGLDVVGGREHVRKVVK
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHCCCCCEECCCHHHHHHHHH
TLRDAEIEVSLFIDPDLDQVKAAHRAEAEVVELHTGRYCDARLASDRRRELSRVIDACKA
HHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAKLGLRVAAGHGLNYQNVVPVAAIPEIEELNIGHSIVARAVLVGFERAVREMRELLREA
HHHHCCCEECCCCCCCCCCCCHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA