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The map label for this gene is acpS

Identifier: 220917554

GI number: 220917554

Start: 2712130

End: 2712516

Strand: Reverse

Name: acpS

Synonym: A2cp1_2454

Alternate gene names: 220917554

Gene position: 2712516-2712130 (Counterclockwise)

Preceding gene: 220917555

Following gene: 220917553

Centisome position: 53.93

GC content: 78.81

Gene sequence:

>387_bases
GTGATCCTGGGGCTCGGCCTGGACGTGGTGGAGGTGGCCCGGATCCAGCGGATCCTGGCGGGCCCGCCCGCGCGCGCGGA
GCGGTTCCTGGCGCGGGTGTTCGCGCCCGCCGAGCGCGCCTACTGCGACGCGCGGCAGGACCGGGCCACCCGGTACGCCG
CGCGCTTCGCCGCGAAGGAGGCGGCGGTGAAGGCGCTCGGGACGCCGGAGGGGGTCCGCTGGCTGGACCTGGTGGTGGAG
CGCGGCGGCGGCGCGCCGTCGCTGGTGCTCGACGGCATCGCGGCCGACGCGGCGCGGCGCCTGGGCGTCGCGCGCGTGCA
CCTCACGCTCACGCACGACGGCGGCGTGGCGGTCGCGGCGGTGATCCTGGAGGGGACCGGGCCATGA

Upstream 100 bases:

>100_bases
GCGGTGCTGGTGGGGTTCGAGCGCGCGGTGCGCGAGATGCGCGAGCTGCTGCGCGAGGCGCGCCCGTAGCGCGGCGCCGC
CCGGCGAGCGAGGAGCGGGC

Downstream 100 bases:

>100_bases
GGCTGGTGGGCGCGGCGGAGATGCGCGCGATCGACCGGGCCGCCATCGACGGGCTGGGGATCCCCTCGCTCGAGCTGATG
GAGCGCGCCGGGCGGGCGGC

Product: holo-acyl-carrier-protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MILGLGLDVVEVARIQRILAGPPARAERFLARVFAPAERAYCDARQDRATRYAARFAAKEAAVKALGTPEGVRWLDLVVE
RGGGAPSLVLDGIAADAARRLGVARVHLTLTHDGGVAVAAVILEGTGP

Sequences:

>Translated_128_residues
MILGLGLDVVEVARIQRILAGPPARAERFLARVFAPAERAYCDARQDRATRYAARFAAKEAAVKALGTPEGVRWLDLVVE
RGGGAPSLVLDGIAADAARRLGVARVHLTLTHDGGVAVAAVILEGTGP
>Mature_128_residues
MILGLGLDVVEVARIQRILAGPPARAERFLARVFAPAERAYCDARQDRATRYAARFAAKEAAVKALGTPEGVRWLDLVVE
RGGGAPSLVLDGIAADAARRLGVARVHLTLTHDGGVAVAAVILEGTGP

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=127, Percent_Identity=40.1574803149606, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_ANAD2 (B8JBG5)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002492858.1
- ProteinModelPortal:   B8JBG5
- SMR:   B8JBG5
- GeneID:   7296937
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_2454
- HOGENOM:   HBG734479
- ProtClustDB:   CLSK945670
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13406; Mature: 13406

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGLGLDVVEVARIQRILAGPPARAERFLARVFAPAERAYCDARQDRATRYAARFAAKE
CEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AAVKALGTPEGVRWLDLVVERGGGAPSLVLDGIAADAARRLGVARVHLTLTHDGGVAVAA
HHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEEE
VILEGTGP
EEEECCCC
>Mature Secondary Structure
MILGLGLDVVEVARIQRILAGPPARAERFLARVFAPAERAYCDARQDRATRYAARFAAKE
CEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AAVKALGTPEGVRWLDLVVERGGGAPSLVLDGIAADAARRLGVARVHLTLTHDGGVAVAA
HHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEEE
VILEGTGP
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA