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The map label for this gene is prkA [H]

Identifier: 220917504

GI number: 220917504

Start: 2662280

End: 2664541

Strand: Reverse

Name: prkA [H]

Synonym: A2cp1_2404

Alternate gene names: 220917504

Gene position: 2664541-2662280 (Counterclockwise)

Preceding gene: 220917506

Following gene: 220917503

Centisome position: 52.98

GC content: 73.74

Gene sequence:

>2262_bases
ATGGACGCGCAGCGCTGGCTGGCGAACGTCGGGTCGGGCGTGAAGGGCGCGTTCGTGGCGAACCGCTCGATCCTGTCCTA
CCCGGAGTACCTGCAGGCCTTCCTCGAGGCGCCGCGGGCCCACGCGCGCTCCGCCGCCCAGTACCTGCGCGACGTCCTCG
ATCACTTCGGATCCGAGGAGCGGGAGACGCCGGTCGGGCGGGTGCGCCGCTTCAGGCTGTTCGACCTCCCGTTCGATCCG
GACGGCCGGCAGCACCGCGTGGCCGGGCAGGAGGAGGTCCAGGCCGCGATCTACCGCGCGCTCGGCGCGTTCGTCCGCAG
CGGCCGGGTGAACAAGCTGGTGCTGCTGCACGGGCCGAACGGCTCGGCGAAGTCGTCGATCGTCTCGGCGCTGATCCGCG
GGATGGAGGCGTACTCGCGCACGCCGGAGGGGACGCTCTACCGGTTCCACTGGGTGTTCCCGAGCGGCCGCGCCGGCCGC
GGCGGGGGCCTCGGGTTCGGCGGCGGGCGCGGCGACGAGCCGGAGCTGCCCAGCTTCGCGCACCTGGAGGGCGACGCGCT
GGACGCGCGGCTCTCCTGCCCGATGAAGGACCACCCGCTGCTGCTCGTGCCGCGCGCCGAGCGGCGGGCGCTGCTCGAGG
AGCGCTGCCGGCCGAGCTCGCGCGAGGGGGCGGGGGAGCGCGACTTCGTGCTCTCCGACTACCTGCTCGACGGCGAGGTC
TGCCAGTACTGCCGGCAGGTGCACGACGCGCTGCTGGCCGCGTACCGCGGCGACTGGCTCAAGGTGCTGCGCCACGTCCA
GGTCGAGCGCCTCTACGTGTCGGCGCGCTACCAGCAGGCGGCGGTCACGCTCGAGCCGCAGCTGTCGGTGGACGCCGGCT
ACCGGCAGGTCACGGTGGACCGCAGCGCCGCCGCGCTGCCGCCCGCGCTGCACGCGTTGACGCTGCTCGAACCGGCCGGG
CCGCTGGTGGCCGGGAACCGCGGGCTGGTGGAGTACTCCGACCTGCTGAAGCGCCCGCCGGAGGCGTTCAAGTACCTGCT
CGGCATGGCCGAGACGGGCCGGGTCGCGCTCGATCAGATCCTGCTGCAGCTCGACGCGGTGCTCATCGCGAGCGCGAACG
AGAAGCAGCTCTCCGCGTTCAAGGAGTCGCCCGACTTCGCCTCGTACAAGGGCCGGCTGGAGCTGGTGCGCGTGCCGTAC
CTGCGCCGCGCGTCGGTGGAGCGCGAGGTGTACGACCAGCAGATCACCTCGGCGGCGGTCGGTCGCCACGTGGCCCCGCA
CGCGACCGAGGTGGCCGCGCGCTGGGCGGTGCTGACGCGGCTGAAGCGGCCGCTCCCCGAGCGCTACGAGGGCGAGCTGC
GCGGCCTGGTGGAGGAGCTGGCGCCGCTCGAGAAGCTGCGCCTGTACGACGCCGGCGCGGCGCCGGACCGGCTCTCGCTC
GCGCAGGGCAAGGTGCTGCGCAAGCACGCCCCCGACCTCTACCGCGAGTCGGAGTCGTACCCGAACTACGAGGGGCGCAT
GGGCGCCTCGGCGCGCGAGGTCAAGACCGCGCTCCTGAACGCGGCCCAGTCGCCCGCCACGCGCTGCCTCACCCCGCGCG
CCGTGCTGGACGAGCTGCGGGCGATCTGCCGCGACCGCACCGTGCACGACTTCCTCCAGCAGGAGGTGGTGGACGGCTAC
CACGACCACGAGGCGTTCGTGCGCGTGGTCGAGGCGGAGGTGCTCGACGCGGTGGACGAGGAGATCCGCGAGTCGATGGG
CCTCGTCTCCGAGGCCCAGTACCGCGAGCTGTTCGGCCGCCACGTCGCGCTCGTCTCGCACTGGGTGCGGGGCGAGAAGA
TCCGCAACGCCGTCACCGGCGAGTACGCCCCGGCCGACGAGGCGCGCATGGTCGAGCTGGAGAAGGTCGTGATGCCGGAG
GGCGAGGACCGCACCGCGTTCCGGCGCGGCCTCATCGCGGCGGTCGGGGCGTACCGCCTCGACCACCCCGACGCGGCCGA
GATCGACTACGTGGCGATCTTCCCGGACCTGTTCCGGCGGCTGCGCGAGCACACGTACGAGGAGCGCCGGCGGGAGCTGG
GACGGGCGACCGACGGCCTGCTCCGCTACCTCTCCGACGAGCGCGCGTCGCTCGACGAGAAGGCGCGGCGGCAGGTCGAG
CGCACGCTCGCCGCGATGCGCGACCGCTACGGCTACTGCGAGGACTGCGCGCGCGACGCGATCCTGTTCCTGACGCGGCG
GCGCTACGACGCGCCCGCCTGA

Upstream 100 bases:

>100_bases
GAGTGCCCGCCGTGCGTGCACGCACACACGCGCCCGCCCGCCCGGCCGTTGGCGCGGCGGTCGCCCCGTGCCACGGTTAG
GAACCGCTGGGAGGCCACCC

Downstream 100 bases:

>100_bases
CGGCCGAGTGAGCGCACGCCGTGGTCGCGAGTCCGTCCGCAAAGGCGAGGGAATTGCCTGTTCGGGTCCGCCGTTCCGGA
TTTCGTGCCCCGCTATCGAC

Product: serine protein kinase, PrkA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 753

Protein sequence:

>753_residues
MDAQRWLANVGSGVKGAFVANRSILSYPEYLQAFLEAPRAHARSAAQYLRDVLDHFGSEERETPVGRVRRFRLFDLPFDP
DGRQHRVAGQEEVQAAIYRALGAFVRSGRVNKLVLLHGPNGSAKSSIVSALIRGMEAYSRTPEGTLYRFHWVFPSGRAGR
GGGLGFGGGRGDEPELPSFAHLEGDALDARLSCPMKDHPLLLVPRAERRALLEERCRPSSREGAGERDFVLSDYLLDGEV
CQYCRQVHDALLAAYRGDWLKVLRHVQVERLYVSARYQQAAVTLEPQLSVDAGYRQVTVDRSAAALPPALHALTLLEPAG
PLVAGNRGLVEYSDLLKRPPEAFKYLLGMAETGRVALDQILLQLDAVLIASANEKQLSAFKESPDFASYKGRLELVRVPY
LRRASVEREVYDQQITSAAVGRHVAPHATEVAARWAVLTRLKRPLPERYEGELRGLVEELAPLEKLRLYDAGAAPDRLSL
AQGKVLRKHAPDLYRESESYPNYEGRMGASAREVKTALLNAAQSPATRCLTPRAVLDELRAICRDRTVHDFLQQEVVDGY
HDHEAFVRVVEAEVLDAVDEEIRESMGLVSEAQYRELFGRHVALVSHWVRGEKIRNAVTGEYAPADEARMVELEKVVMPE
GEDRTAFRRGLIAAVGAYRLDHPDAAEIDYVAIFPDLFRRLREHTYEERRRELGRATDGLLRYLSDERASLDEKARRQVE
RTLAAMRDRYGYCEDCARDAILFLTRRRYDAPA

Sequences:

>Translated_753_residues
MDAQRWLANVGSGVKGAFVANRSILSYPEYLQAFLEAPRAHARSAAQYLRDVLDHFGSEERETPVGRVRRFRLFDLPFDP
DGRQHRVAGQEEVQAAIYRALGAFVRSGRVNKLVLLHGPNGSAKSSIVSALIRGMEAYSRTPEGTLYRFHWVFPSGRAGR
GGGLGFGGGRGDEPELPSFAHLEGDALDARLSCPMKDHPLLLVPRAERRALLEERCRPSSREGAGERDFVLSDYLLDGEV
CQYCRQVHDALLAAYRGDWLKVLRHVQVERLYVSARYQQAAVTLEPQLSVDAGYRQVTVDRSAAALPPALHALTLLEPAG
PLVAGNRGLVEYSDLLKRPPEAFKYLLGMAETGRVALDQILLQLDAVLIASANEKQLSAFKESPDFASYKGRLELVRVPY
LRRASVEREVYDQQITSAAVGRHVAPHATEVAARWAVLTRLKRPLPERYEGELRGLVEELAPLEKLRLYDAGAAPDRLSL
AQGKVLRKHAPDLYRESESYPNYEGRMGASAREVKTALLNAAQSPATRCLTPRAVLDELRAICRDRTVHDFLQQEVVDGY
HDHEAFVRVVEAEVLDAVDEEIRESMGLVSEAQYRELFGRHVALVSHWVRGEKIRNAVTGEYAPADEARMVELEKVVMPE
GEDRTAFRRGLIAAVGAYRLDHPDAAEIDYVAIFPDLFRRLREHTYEERRRELGRATDGLLRYLSDERASLDEKARRQVE
RTLAAMRDRYGYCEDCARDAILFLTRRRYDAPA
>Mature_753_residues
MDAQRWLANVGSGVKGAFVANRSILSYPEYLQAFLEAPRAHARSAAQYLRDVLDHFGSEERETPVGRVRRFRLFDLPFDP
DGRQHRVAGQEEVQAAIYRALGAFVRSGRVNKLVLLHGPNGSAKSSIVSALIRGMEAYSRTPEGTLYRFHWVFPSGRAGR
GGGLGFGGGRGDEPELPSFAHLEGDALDARLSCPMKDHPLLLVPRAERRALLEERCRPSSREGAGERDFVLSDYLLDGEV
CQYCRQVHDALLAAYRGDWLKVLRHVQVERLYVSARYQQAAVTLEPQLSVDAGYRQVTVDRSAAALPPALHALTLLEPAG
PLVAGNRGLVEYSDLLKRPPEAFKYLLGMAETGRVALDQILLQLDAVLIASANEKQLSAFKESPDFASYKGRLELVRVPY
LRRASVEREVYDQQITSAAVGRHVAPHATEVAARWAVLTRLKRPLPERYEGELRGLVEELAPLEKLRLYDAGAAPDRLSL
AQGKVLRKHAPDLYRESESYPNYEGRMGASAREVKTALLNAAQSPATRCLTPRAVLDELRAICRDRTVHDFLQQEVVDGY
HDHEAFVRVVEAEVLDAVDEEIRESMGLVSEAQYRELFGRHVALVSHWVRGEKIRNAVTGEYAPADEARMVELEKVVMPE
GEDRTAFRRGLIAAVGAYRLDHPDAAEIDYVAIFPDLFRRLREHTYEERRRELGRATDGLLRYLSDERASLDEKARRQVE
RTLAAMRDRYGYCEDCARDAILFLTRRRYDAPA

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=350, Percent_Identity=22.2857142857143, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 84584; Mature: 84584

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAQRWLANVGSGVKGAFVANRSILSYPEYLQAFLEAPRAHARSAAQYLRDVLDHFGSEE
CCHHHHHHHHCCCCCCHHHCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
RETPVGRVRRFRLFDLPFDPDGRQHRVAGQEEVQAAIYRALGAFVRSGRVNKLVLLHGPN
CCCCHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GSAKSSIVSALIRGMEAYSRTPEGTLYRFHWVFPSGRAGRGGGLGFGGGRGDEPELPSFA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
HLEGDALDARLSCPMKDHPLLLVPRAERRALLEERCRPSSREGAGERDFVLSDYLLDGEV
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCHHH
CQYCRQVHDALLAAYRGDWLKVLRHVQVERLYVSARYQQAAVTLEPQLSVDAGYRQVTVD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEC
RSAAALPPALHALTLLEPAGPLVAGNRGLVEYSDLLKRPPEAFKYLLGMAETGRVALDQI
CCHHHCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHHHH
LLQLDAVLIASANEKQLSAFKESPDFASYKGRLELVRVPYLRRASVEREVYDQQITSAAV
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GRHVAPHATEVAARWAVLTRLKRPLPERYEGELRGLVEELAPLEKLRLYDAGAAPDRLSL
HCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AQGKVLRKHAPDLYRESESYPNYEGRMGASAREVKTALLNAAQSPATRCLTPRAVLDELR
HHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHH
AICRDRTVHDFLQQEVVDGYHDHEAFVRVVEAEVLDAVDEEIRESMGLVSEAQYRELFGR
HHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
HVALVSHWVRGEKIRNAVTGEYAPADEARMVELEKVVMPEGEDRTAFRRGLIAAVGAYRL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
DHPDAAEIDYVAIFPDLFRRLREHTYEERRRELGRATDGLLRYLSDERASLDEKARRQVE
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RTLAAMRDRYGYCEDCARDAILFLTRRRYDAPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDAQRWLANVGSGVKGAFVANRSILSYPEYLQAFLEAPRAHARSAAQYLRDVLDHFGSEE
CCHHHHHHHHCCCCCCHHHCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
RETPVGRVRRFRLFDLPFDPDGRQHRVAGQEEVQAAIYRALGAFVRSGRVNKLVLLHGPN
CCCCHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GSAKSSIVSALIRGMEAYSRTPEGTLYRFHWVFPSGRAGRGGGLGFGGGRGDEPELPSFA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
HLEGDALDARLSCPMKDHPLLLVPRAERRALLEERCRPSSREGAGERDFVLSDYLLDGEV
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCHHH
CQYCRQVHDALLAAYRGDWLKVLRHVQVERLYVSARYQQAAVTLEPQLSVDAGYRQVTVD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEC
RSAAALPPALHALTLLEPAGPLVAGNRGLVEYSDLLKRPPEAFKYLLGMAETGRVALDQI
CCHHHCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHHHH
LLQLDAVLIASANEKQLSAFKESPDFASYKGRLELVRVPYLRRASVEREVYDQQITSAAV
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GRHVAPHATEVAARWAVLTRLKRPLPERYEGELRGLVEELAPLEKLRLYDAGAAPDRLSL
HCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AQGKVLRKHAPDLYRESESYPNYEGRMGASAREVKTALLNAAQSPATRCLTPRAVLDELR
HHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHH
AICRDRTVHDFLQQEVVDGYHDHEAFVRVVEAEVLDAVDEEIRESMGLVSEAQYRELFGR
HHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
HVALVSHWVRGEKIRNAVTGEYAPADEARMVELEKVVMPEGEDRTAFRRGLIAAVGAYRL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
DHPDAAEIDYVAIFPDLFRRLREHTYEERRRELGRATDGLLRYLSDERASLDEKARRQVE
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RTLAAMRDRYGYCEDCARDAILFLTRRRYDAPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]