Click here to switch to the map view.

The map label for this gene is fur [H]

Identifier: 220917488

GI number: 220917488

Start: 2646539

End: 2647042

Strand: Reverse

Name: fur [H]

Synonym: A2cp1_2388

Alternate gene names: 220917488

Gene position: 2647042-2646539 (Counterclockwise)

Preceding gene: 220917489

Following gene: 220917487

Centisome position: 52.63

GC content: 74.01

Gene sequence:

>504_bases
ATGAAGGGCTCGAGCAGGCCGCGGGAGGGCAGCGGGTCGGCGCAGGTGTCCGGTCCCACGGCCACGCTCGCCGCGTACAT
CCAGGAGCGCGGCCTCAAGCAGTCGCGGCAGCGCGAGCGCATCGCCCAGTCGTTCTTCGCCATGGGTGGCCACGTCACCG
TCGAGCAGCTGGTCGCGCGCGTGCGGCGGGACGACCCGCGGGTCAGCGTCGCCACCGTGTACCGCACCATGAAGCTGCTG
GCCGAGTGCGGCCTGGCGGTGGCGCGGCAGTTCGGCGACGGGCAGACGCGCTACGAGGCGTCGGCCGGGCGCGATCACCA
CGATCACCTGATCTGCACCGCCTGCGGCGAGATCATCGAGTTCGCGAACGAGCGGATCGAGAGCCTGCAGGAGGTGGTGG
CGCGCCGCCACGGCTTCGAGGTCGAGAGCCACCGCCTCGAGCTGTACGGCCGCTGCGCCCGGTGCCGCCCGCCGGGCCGC
GCCCGCCCGGAGGCGCGCCCGTGA

Upstream 100 bases:

>100_bases
GGCGCGGACCGGAGCAGGCACACGGTCTGGGGCTTGTGTCCGGTGCCGTGGTCTGATATTGAGAACCATTATCAACATGA
ACACCGAACGGGACGACAGG

Downstream 100 bases:

>100_bases
CGCCTCCTCCCCCGGAGGCCGCCGCGCGCCACGAGGCCGACCTCGATCGCAAGCAGGTGGTCTCGGCCGCGCGGTCCGTG
ATCCTGGTCGGCAACCCGAA

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKGSSRPREGSGSAQVSGPTATLAAYIQERGLKQSRQRERIAQSFFAMGGHVTVEQLVARVRRDDPRVSVATVYRTMKLL
AECGLAVARQFGDGQTRYEASAGRDHHDHLICTACGEIIEFANERIESLQEVVARRHGFEVESHRLELYGRCARCRPPGR
ARPEARP

Sequences:

>Translated_167_residues
MKGSSRPREGSGSAQVSGPTATLAAYIQERGLKQSRQRERIAQSFFAMGGHVTVEQLVARVRRDDPRVSVATVYRTMKLL
AECGLAVARQFGDGQTRYEASAGRDHHDHLICTACGEIIEFANERIESLQEVVARRHGFEVESHRLELYGRCARCRPPGR
ARPEARP
>Mature_167_residues
MKGSSRPREGSGSAQVSGPTATLAAYIQERGLKQSRQRERIAQSFFAMGGHVTVEQLVARVRRDDPRVSVATVYRTMKLL
AECGLAVARQFGDGQTRYEASAGRDHHDHLICTACGEIIEFANERIESLQEVVARRHGFEVESHRLELYGRCARCRPPGR
ARPEARP

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=139, Percent_Identity=33.8129496402878, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18603; Mature: 18603

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSSRPREGSGSAQVSGPTATLAAYIQERGLKQSRQRERIAQSFFAMGGHVTVEQLVAR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VRRDDPRVSVATVYRTMKLLAECGLAVARQFGDGQTRYEASAGRDHHDHLICTACGEIIE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHH
FANERIESLQEVVARRHGFEVESHRLELYGRCARCRPPGRARPEARP
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKGSSRPREGSGSAQVSGPTATLAAYIQERGLKQSRQRERIAQSFFAMGGHVTVEQLVAR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VRRDDPRVSVATVYRTMKLLAECGLAVARQFGDGQTRYEASAGRDHHDHLICTACGEIIE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHH
FANERIESLQEVVARRHGFEVESHRLELYGRCARCRPPGRARPEARP
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]