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The map label for this gene is cph2 [H]

Identifier: 220917475

GI number: 220917475

Start: 2633460

End: 2635754

Strand: Reverse

Name: cph2 [H]

Synonym: A2cp1_2375

Alternate gene names: 220917475

Gene position: 2635754-2633460 (Counterclockwise)

Preceding gene: 220917476

Following gene: 220917474

Centisome position: 52.41

GC content: 75.21

Gene sequence:

>2295_bases
GTGAGCGAGCCGCTCCCCGCGCTGCCGCCGGTGCGCGCGCCGGTGGGCGCCACGCCCACGGTGCGCCGCCGCCTGGCGCT
GCAGCGCTCGCGGCCCCTGCTCATCCGCGCGTACGCGCTGCTGCTCGGCGACGCGGGGCTGGCCGGCCCCATCGCCCGTC
GCCGGGCGGCGCGCTTCGTCCTGCGCAGCCTGCCGGCGCTGGTCACGGTGGCGGTGGGCGCGCTGGTGGCGCTGCGCGGC
TTCGAGTCCGCCGCGGGCTGGGGTCAGGTAGCCGCCATGGCGGTCCTGGCGGTCGCGCTCGGCGCGCTGGTGTGGCGCCG
GGTGGCGCGCGCGGCCGCGGGGGAGCAGGCGGGCTACCGCGAGCAGCTCGAGCTGGGCTCGCTGTTCGTGGTGGCGGCGT
ACGCGGTGGCGCAGAGCGCGAGCTTCGGGCACGCCGAGTCGGCGTTCCAGCCGGTGGTCTACCTGGTGATGGCGTTCCTG
GTGGCGTTCCTCGCCCCGGGCGTCGGCGCCGGGCTGGTGGCGCTCGCGGTGACGCTGGAGGCGCTGCTGTGGGCCGGGCG
CGGCGCGCGGGTGGCGGAGCTGCCCGAGGCGGTGGTGCACGCCGGCTTCGTGACCGTGTTCGCGGTGCTCTACTACGCCG
TGCTGGCCGGGCAGGTCGCCGCCAGCCGGCGCGACGAGCGGCTCGCCATCGAGCGGCGCATGAAGGAGATCGACCACCTG
GCGCGCGCGTTCCGGCTGAGCGTGGCGGCGCCGGACGACGCGCAGGATCCGGCCGAGCGCGAGCGCCGCTGGAGCGAGGG
CGCGGTGATCGAGATCGAGGCGGCGGTGGGCGGGGCGCTGGAGGTCGCGGTGGCCGCCCTGCGCTGTCACACCTGCGCGC
TGTTCTGGCTGAGCGAGGACGAGAAGACGCTCACGCTGCTCGACTGCCGCTCGCCCAGCGAGGCGGTGGGCCGCGAGCCG
CTGCCGGCCGGGGAAGGCCCGCTGGGCGGCGCGGTGCGCCGCCGCTCCCCGGTGCGGCTCCACGGCGAGGTGAAGGCGGT
CAGCTACTACGCGGACGGCACCCGGCCGAAGGCGCTGCTCGCCGCGCCGCTGGTGGACCCGCGCGGCGGCCACGTGCGCG
GCGTCGTGCTGGTGGACCGGATGGAGCCGACGCCGTTCACCGAGGCCGAGGAGAAGCTCCTCGTCACGCTGGCCGCCGAG
ATCCTGCGGGCGGTCGGCGCCGAGCGGCTGATGAAGGACGTCCGCCAGACGCGCGCGGAGGTGGACCGGTTCTACCGGTC
CATCGAGCGGCTGAACCGCACCCGGAAGCTCTCGGAGGTCTACGACGCGCTGGTGGGCGTGGCGTCGGAGATGGTCACGG
TGGACTTCGCCGCGGTGGCGCTGCGCGACGAGGTGGATCCGTCCAGGGTGCGCGTGGTGCGCGTGGCGGGCGGGGAGGGC
GATCGCACCGGCGCGGCCGGCCTCGACGACCTCGAGTTCGCCATGGGCGACGGCTGCCTGGTGTCCTCGGCCATCAAGAT
CGACGACGTGCTCCCGGTGAACGCGCTCGATCCCGCGAAGACGCGGGTGTTCGGCGCGGTCTGCCTGCGCGGCCTCGCCT
CGCTCAAGATCTTCCCGCTCAAGGTGGGCGAGCGCTCCATCGGCGCGCTCGTGCTGGGCGCCAAGCGCGCCGGCGCGTAC
GGCCGCGACGCCGTCCAGCAACTGCTCGTGATCTCGATGCACGCGGCCCAGTCGATCGACCGCGCGCGCCTGTTCGACCA
GACCGAGCGGCTCGCCACCACCGACGGCCTCACCGGCCTCACGAACCATCGGACGTTCCAGGAGCGGCTGGACGCGCACC
TCGGCCAGGCGCAGCGGTACGGGAAGCGGACGTCGCTCTTGCTGTGCGACATCGACCACTTCAAGTCGGTGAACGACACG
TACGGCCACCCGGTGGGCGATCAGGTGCTGCGCGGGGTGGCGAGGACGCTGGCGCGGGCCGCGCGCGGCACCGACGTGGT
GGCCCGCTACGGCGGCGAGGAGTTCGCCATCGTCATGCCCGAGACCGACACGGGCGGCGCGATGGTGATCGCCGAGCGCA
TCCGCGAGAAGGTCGGGCAGCTCGTCTTCGAGACCGAGCAGGGTCCCCTCAAGGTGACCCTGTCGCTCGGGGTCGCCACC
TTCCCCGACGACGGGGCGCAGAAGCCGGCGCTGATCGAGCGCGCCGACGCCTGCCTCTACCACGCCAAGCGGCACGGCCG
GAACCAGAGCGTCTCGGCGGCCAGCCTCCGCGCCCCTCGCCGCGCCGCGGTGTGA

Upstream 100 bases:

>100_bases
CCGAGCCCGCCGCGCTGGAGCGCGCCGTGCGCGAGGAGCTCCGGTACATCCGCCCGGGCGAGCGGGTCTACTGGCTGGGC
GCCGAGCGCGGAGGGGCCCC

Downstream 100 bases:

>100_bases
GGGTCGGTCCGCCGCGGCGGTGGCCGTCGCCGCCCGCGCCCTGCTAGACTTCGGTCCGCGCCGTCCGTCCCCTGGACGGC
CTCGCCCGGAGCCGCCCAGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 764; Mature: 763

Protein sequence:

>764_residues
MSEPLPALPPVRAPVGATPTVRRRLALQRSRPLLIRAYALLLGDAGLAGPIARRRAARFVLRSLPALVTVAVGALVALRG
FESAAGWGQVAAMAVLAVALGALVWRRVARAAAGEQAGYREQLELGSLFVVAAYAVAQSASFGHAESAFQPVVYLVMAFL
VAFLAPGVGAGLVALAVTLEALLWAGRGARVAELPEAVVHAGFVTVFAVLYYAVLAGQVAASRRDERLAIERRMKEIDHL
ARAFRLSVAAPDDAQDPAERERRWSEGAVIEIEAAVGGALEVAVAALRCHTCALFWLSEDEKTLTLLDCRSPSEAVGREP
LPAGEGPLGGAVRRRSPVRLHGEVKAVSYYADGTRPKALLAAPLVDPRGGHVRGVVLVDRMEPTPFTEAEEKLLVTLAAE
ILRAVGAERLMKDVRQTRAEVDRFYRSIERLNRTRKLSEVYDALVGVASEMVTVDFAAVALRDEVDPSRVRVVRVAGGEG
DRTGAAGLDDLEFAMGDGCLVSSAIKIDDVLPVNALDPAKTRVFGAVCLRGLASLKIFPLKVGERSIGALVLGAKRAGAY
GRDAVQQLLVISMHAAQSIDRARLFDQTERLATTDGLTGLTNHRTFQERLDAHLGQAQRYGKRTSLLLCDIDHFKSVNDT
YGHPVGDQVLRGVARTLARAARGTDVVARYGGEEFAIVMPETDTGGAMVIAERIREKVGQLVFETEQGPLKVTLSLGVAT
FPDDGAQKPALIERADACLYHAKRHGRNQSVSAASLRAPRRAAV

Sequences:

>Translated_764_residues
MSEPLPALPPVRAPVGATPTVRRRLALQRSRPLLIRAYALLLGDAGLAGPIARRRAARFVLRSLPALVTVAVGALVALRG
FESAAGWGQVAAMAVLAVALGALVWRRVARAAAGEQAGYREQLELGSLFVVAAYAVAQSASFGHAESAFQPVVYLVMAFL
VAFLAPGVGAGLVALAVTLEALLWAGRGARVAELPEAVVHAGFVTVFAVLYYAVLAGQVAASRRDERLAIERRMKEIDHL
ARAFRLSVAAPDDAQDPAERERRWSEGAVIEIEAAVGGALEVAVAALRCHTCALFWLSEDEKTLTLLDCRSPSEAVGREP
LPAGEGPLGGAVRRRSPVRLHGEVKAVSYYADGTRPKALLAAPLVDPRGGHVRGVVLVDRMEPTPFTEAEEKLLVTLAAE
ILRAVGAERLMKDVRQTRAEVDRFYRSIERLNRTRKLSEVYDALVGVASEMVTVDFAAVALRDEVDPSRVRVVRVAGGEG
DRTGAAGLDDLEFAMGDGCLVSSAIKIDDVLPVNALDPAKTRVFGAVCLRGLASLKIFPLKVGERSIGALVLGAKRAGAY
GRDAVQQLLVISMHAAQSIDRARLFDQTERLATTDGLTGLTNHRTFQERLDAHLGQAQRYGKRTSLLLCDIDHFKSVNDT
YGHPVGDQVLRGVARTLARAARGTDVVARYGGEEFAIVMPETDTGGAMVIAERIREKVGQLVFETEQGPLKVTLSLGVAT
FPDDGAQKPALIERADACLYHAKRHGRNQSVSAASLRAPRRAAV
>Mature_763_residues
SEPLPALPPVRAPVGATPTVRRRLALQRSRPLLIRAYALLLGDAGLAGPIARRRAARFVLRSLPALVTVAVGALVALRGF
ESAAGWGQVAAMAVLAVALGALVWRRVARAAAGEQAGYREQLELGSLFVVAAYAVAQSASFGHAESAFQPVVYLVMAFLV
AFLAPGVGAGLVALAVTLEALLWAGRGARVAELPEAVVHAGFVTVFAVLYYAVLAGQVAASRRDERLAIERRMKEIDHLA
RAFRLSVAAPDDAQDPAERERRWSEGAVIEIEAAVGGALEVAVAALRCHTCALFWLSEDEKTLTLLDCRSPSEAVGREPL
PAGEGPLGGAVRRRSPVRLHGEVKAVSYYADGTRPKALLAAPLVDPRGGHVRGVVLVDRMEPTPFTEAEEKLLVTLAAEI
LRAVGAERLMKDVRQTRAEVDRFYRSIERLNRTRKLSEVYDALVGVASEMVTVDFAAVALRDEVDPSRVRVVRVAGGEGD
RTGAAGLDDLEFAMGDGCLVSSAIKIDDVLPVNALDPAKTRVFGAVCLRGLASLKIFPLKVGERSIGALVLGAKRAGAYG
RDAVQQLLVISMHAAQSIDRARLFDQTERLATTDGLTGLTNHRTFQERLDAHLGQAQRYGKRTSLLLCDIDHFKSVNDTY
GHPVGDQVLRGVARTLARAARGTDVVARYGGEEFAIVMPETDTGGAMVIAERIREKVGQLVFETEQGPLKVTLSLGVATF
PDDGAQKPALIERADACLYHAKRHGRNQSVSAASLRAPRRAAV

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=192, Percent_Identity=38.5416666666667, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=37.5757575757576, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=41.0112359550562, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693134, Length=191, Percent_Identity=38.2198952879581, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1787802, Length=175, Percent_Identity=36.5714285714286, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788381, Length=181, Percent_Identity=32.0441988950276, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=34.5911949685535, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787816, Length=161, Percent_Identity=37.888198757764, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788085, Length=193, Percent_Identity=29.5336787564767, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=34.375, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081977, Length=228, Percent_Identity=25.4385964912281, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788956, Length=161, Percent_Identity=34.1614906832298, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787056, Length=202, Percent_Identity=30.1980198019802, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081974, Length=168, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081921, Length=193, Percent_Identity=24.8704663212435, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 81731; Mature: 81600

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50887 GGDEF ; PS00392 DDC_GAD_HDC_YDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLPALPPVRAPVGATPTVRRRLALQRSRPLLIRAYALLLGDAGLAGPIARRRAARFV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LRSLPALVTVAVGALVALRGFESAAGWGQVAAMAVLAVALGALVWRRVARAAAGEQAGYR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EQLELGSLFVVAAYAVAQSASFGHAESAFQPVVYLVMAFLVAFLAPGVGAGLVALAVTLE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALLWAGRGARVAELPEAVVHAGFVTVFAVLYYAVLAGQVAASRRDERLAIERRMKEIDHL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARAFRLSVAAPDDAQDPAERERRWSEGAVIEIEAAVGGALEVAVAALRCHTCALFWLSED
HHHHHHEECCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEEEECC
EKTLTLLDCRSPSEAVGREPLPAGEGPLGGAVRRRSPVRLHGEVKAVSYYADGTRPKALL
CCEEEEEECCCCHHHHCCCCCCCCCCCCCCHHHCCCCCEEECCEEEEEEECCCCCCCCEE
AAPLVDPRGGHVRGVVLVDRMEPTPFTEAEEKLLVTLAAEILRAVGAERLMKDVRQTRAE
ECCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDRFYRSIERLNRTRKLSEVYDALVGVASEMVTVDFAAVALRDEVDPSRVRVVRVAGGEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
DRTGAAGLDDLEFAMGDGCLVSSAIKIDDVLPVNALDPAKTRVFGAVCLRGLASLKIFPL
CCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEE
KVGERSIGALVLGAKRAGAYGRDAVQQLLVISMHAAQSIDRARLFDQTERLATTDGLTGL
ECCCCCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TNHRTFQERLDAHLGQAQRYGKRTSLLLCDIDHFKSVNDTYGHPVGDQVLRGVARTLARA
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ARGTDVVARYGGEEFAIVMPETDTGGAMVIAERIREKVGQLVFETEQGPLKVTLSLGVAT
HCCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECEEE
FPDDGAQKPALIERADACLYHAKRHGRNQSVSAASLRAPRRAAV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCC
>Mature Secondary Structure 
SEPLPALPPVRAPVGATPTVRRRLALQRSRPLLIRAYALLLGDAGLAGPIARRRAARFV
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LRSLPALVTVAVGALVALRGFESAAGWGQVAAMAVLAVALGALVWRRVARAAAGEQAGYR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EQLELGSLFVVAAYAVAQSASFGHAESAFQPVVYLVMAFLVAFLAPGVGAGLVALAVTLE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALLWAGRGARVAELPEAVVHAGFVTVFAVLYYAVLAGQVAASRRDERLAIERRMKEIDHL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARAFRLSVAAPDDAQDPAERERRWSEGAVIEIEAAVGGALEVAVAALRCHTCALFWLSED
HHHHHHEECCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEEEECC
EKTLTLLDCRSPSEAVGREPLPAGEGPLGGAVRRRSPVRLHGEVKAVSYYADGTRPKALL
CCEEEEEECCCCHHHHCCCCCCCCCCCCCCHHHCCCCCEEECCEEEEEEECCCCCCCCEE
AAPLVDPRGGHVRGVVLVDRMEPTPFTEAEEKLLVTLAAEILRAVGAERLMKDVRQTRAE
ECCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDRFYRSIERLNRTRKLSEVYDALVGVASEMVTVDFAAVALRDEVDPSRVRVVRVAGGEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
DRTGAAGLDDLEFAMGDGCLVSSAIKIDDVLPVNALDPAKTRVFGAVCLRGLASLKIFPL
CCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEE
KVGERSIGALVLGAKRAGAYGRDAVQQLLVISMHAAQSIDRARLFDQTERLATTDGLTGL
ECCCCCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TNHRTFQERLDAHLGQAQRYGKRTSLLLCDIDHFKSVNDTYGHPVGDQVLRGVARTLARA
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ARGTDVVARYGGEEFAIVMPETDTGGAMVIAERIREKVGQLVFETEQGPLKVTLSLGVAT
HCCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECEEE
FPDDGAQKPALIERADACLYHAKRHGRNQSVSAASLRAPRRAAV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]