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The map label for this gene is zraR [H]

Identifier: 220915840

GI number: 220915840

Start: 814012

End: 815436

Strand: Reverse

Name: zraR [H]

Synonym: A2cp1_0723

Alternate gene names: 220915840

Gene position: 815436-814012 (Counterclockwise)

Preceding gene: 220915841

Following gene: 220915839

Centisome position: 16.21

GC content: 74.32

Gene sequence:

>1425_bases
GTGTCCCCACTGGTCCTGGTCGTCGACGACGAGAGCCCGAACCTCGAGTCGCTCGGCAAGATCTTCGAGCGCGAGGGCTG
GCGCGTGGCGCTCGCCGCCTCCGGCCTCGCCGCGCTGGAGCTGCTCCGCCGCGAGCGCGCCGCGGTGGTGGTCACCGACC
TGATGATGCCGGGCATGAGCGGCGACGAGCTGCTCCGCGCGGTGAAGGCGGTGTCGCCCGAGTCCGAGGTGGTGGTGATG
ACCGCCTACGGCACGGTCGAGGTGGCGGTCGCCGCCATGAAGCAGGGCGCCTACGACTTCATCACCAAGCCGGTGAAGCG
CCACGCCATCGTGAAGACGGTGCGACAGGCGCTGGAGCGCGCGTCGCTCGTCGCCGAGAACCGCGCGCTGAAGGCGCGCC
TGGCGGAGCTCGCGCCCGGCGGCGCGGGCGCGCTCCTGGGCGACGCGCCGGCGTTCCGCGCGACGCTGGAGATCCTGCGC
CAGGCCGCGCCGACGCAGGCCACCGTGCTGCTGCTGGGCGAGAGCGGCACCGGGAAGGAGCTCGCCGCGCGGCTGGTCCA
CGACCTGTCCCCGCGCGCCGCCGGGCCGTTCGTGCCGATCCACTGCGCCGCCATCCCGGAGACGCTGCTCGAGTCCGAGC
TGTTCGGGCACGAGAAGGGCGCGTTCACCGGCGCGGTGGCGCGCAAGGACGGGCGCTTCGAGCGCGCACAGGGTGGCACG
CTGTTCCTCGACGAGATCGGCGAGATGTCGCCCGCGGTGCAGGTGAAGCTGCTCCGGTTCCTGCAGGACGGGGTCCTCGA
GCGCGTGGGCGGGAACGAGCCGGTGCGCGTGGACGTGCGGGTGGTGGCCGCGACCAACAAGGACCTCGCCGCCGAGGTGA
AGGCCGGCCGCTTCCGCGAGGACCTGTTCTACCGGCTCGACGTGGTGCGCGTCCGCCTCCCGCCGCTGCGCGAGCGGCGC
GAGGACGTGCCGCTGCTCGCCATGGCCTTCCTGCGGCGGATGGCCGAGCGCAACGGGAAGCCGCTCGCGGGCTTCACCTC
GGGTGCGATGGCGGCGCTGGAGCGGTACGCCTGGCCGGGCAACGTGCGCGAGCTGCAGCACGCCATCGAGCGGGCGGTAG
TGCTCACCCGCGCCGACGTCGTCGAGGTGGGCGACCTGCCGGAGGCGATCCGCGCCGCGGGACCCGCCGTCCCGGAGCCC
GCCGGCGCGGCCGGGGCCCCGGTGCTCACCGTGCCGCTCGGCACGCCCATGGAGGAGATCGAGCGGCGGGTGATCCGCGA
GACGCTTCGCCACACCCAGGGTGACAAGAACCTGGCGGCCCAGCTGCTAGGCATCGCGGCCCGGACCATCTACCGGAAGC
TCGATCGCGACGAGGAGGGGCGCCTCCTCGTCCCTCCGGAGGGCGGCGGCGAGGGCCCGGAGTAG

Upstream 100 bases:

>100_bases
GCCGGTGGCCCGCACCGCGCCGGGCGCGACGCCCCCTTCCCCGCCGCCCGCCGGCGGCGGCTGACGCCCGGGTGGCGCGG
GACGGTATATCCTCCCGGTC

Downstream 100 bases:

>100_bases
CCTGCCAATTTGGCGGCGACGCGGGGCGCGCCGGGGCGGCCTTGCCAAATTGGCAGCGCGGTGGCCCACGCTCCCCTCGG
GCGGGCGCACCGGCCGGGAT

Product: two component sigma-54 specific Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSPLVLVVDDESPNLESLGKIFEREGWRVALAASGLAALELLRRERAAVVVTDLMMPGMSGDELLRAVKAVSPESEVVVM
TAYGTVEVAVAAMKQGAYDFITKPVKRHAIVKTVRQALERASLVAENRALKARLAELAPGGAGALLGDAPAFRATLEILR
QAAPTQATVLLLGESGTGKELAARLVHDLSPRAAGPFVPIHCAAIPETLLESELFGHEKGAFTGAVARKDGRFERAQGGT
LFLDEIGEMSPAVQVKLLRFLQDGVLERVGGNEPVRVDVRVVAATNKDLAAEVKAGRFREDLFYRLDVVRVRLPPLRERR
EDVPLLAMAFLRRMAERNGKPLAGFTSGAMAALERYAWPGNVRELQHAIERAVVLTRADVVEVGDLPEAIRAAGPAVPEP
AGAAGAPVLTVPLGTPMEEIERRVIRETLRHTQGDKNLAAQLLGIAARTIYRKLDRDEEGRLLVPPEGGGEGPE

Sequences:

>Translated_474_residues
MSPLVLVVDDESPNLESLGKIFEREGWRVALAASGLAALELLRRERAAVVVTDLMMPGMSGDELLRAVKAVSPESEVVVM
TAYGTVEVAVAAMKQGAYDFITKPVKRHAIVKTVRQALERASLVAENRALKARLAELAPGGAGALLGDAPAFRATLEILR
QAAPTQATVLLLGESGTGKELAARLVHDLSPRAAGPFVPIHCAAIPETLLESELFGHEKGAFTGAVARKDGRFERAQGGT
LFLDEIGEMSPAVQVKLLRFLQDGVLERVGGNEPVRVDVRVVAATNKDLAAEVKAGRFREDLFYRLDVVRVRLPPLRERR
EDVPLLAMAFLRRMAERNGKPLAGFTSGAMAALERYAWPGNVRELQHAIERAVVLTRADVVEVGDLPEAIRAAGPAVPEP
AGAAGAPVLTVPLGTPMEEIERRVIRETLRHTQGDKNLAAQLLGIAARTIYRKLDRDEEGRLLVPPEGGGEGPE
>Mature_473_residues
SPLVLVVDDESPNLESLGKIFEREGWRVALAASGLAALELLRRERAAVVVTDLMMPGMSGDELLRAVKAVSPESEVVVMT
AYGTVEVAVAAMKQGAYDFITKPVKRHAIVKTVRQALERASLVAENRALKARLAELAPGGAGALLGDAPAFRATLEILRQ
AAPTQATVLLLGESGTGKELAARLVHDLSPRAAGPFVPIHCAAIPETLLESELFGHEKGAFTGAVARKDGRFERAQGGTL
FLDEIGEMSPAVQVKLLRFLQDGVLERVGGNEPVRVDVRVVAATNKDLAAEVKAGRFREDLFYRLDVVRVRLPPLRERRE
DVPLLAMAFLRRMAERNGKPLAGFTSGAMAALERYAWPGNVRELQHAIERAVVLTRADVVEVGDLPEAIRAAGPAVPEPA
GAAGAPVLTVPLGTPMEEIERRVIRETLRHTQGDKNLAAQLLGIAARTIYRKLDRDEEGRLLVPPEGGGEGPE

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=458, Percent_Identity=46.943231441048, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788550, Length=454, Percent_Identity=43.3920704845815, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1790299, Length=477, Percent_Identity=42.1383647798742, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1788905, Length=454, Percent_Identity=39.2070484581498, Blast_Score=317, Evalue=8e-88,
Organism=Escherichia coli, GI1789087, Length=412, Percent_Identity=40.5339805825243, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI87082152, Length=311, Percent_Identity=47.2668810289389, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI87082117, Length=313, Percent_Identity=46.0063897763578, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1789233, Length=318, Percent_Identity=42.4528301886792, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87081872, Length=311, Percent_Identity=45.016077170418, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1786524, Length=357, Percent_Identity=39.4957983193277, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1787583, Length=306, Percent_Identity=41.8300653594771, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87081858, Length=309, Percent_Identity=33.0097087378641, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1789828, Length=248, Percent_Identity=35.0806451612903, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=152, Percent_Identity=27.6315789473684, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50981; Mature: 50849

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLVLVVDDESPNLESLGKIFEREGWRVALAASGLAALELLRRERAAVVVTDLMMPGMS
CCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHEEEHHHHCCCCC
GDELLRAVKAVSPESEVVVMTAYGTVEVAVAAMKQGAYDFITKPVKRHAIVKTVRQALER
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ASLVAENRALKARLAELAPGGAGALLGDAPAFRATLEILRQAAPTQATVLLLGESGTGKE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHH
LAARLVHDLSPRAAGPFVPIHCAAIPETLLESELFGHEKGAFTGAVARKDGRFERAQGGT
HHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCE
LFLDEIGEMSPAVQVKLLRFLQDGVLERVGGNEPVRVDVRVVAATNKDLAAEVKAGRFRE
EEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHH
DLFYRLDVVRVRLPPLRERREDVPLLAMAFLRRMAERNGKPLAGFTSGAMAALERYAWPG
HHHHHHHHHEECCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
NVRELQHAIERAVVLTRADVVEVGDLPEAIRAAGPAVPEPAGAAGAPVLTVPLGTPMEEI
CHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHH
ERRVIRETLRHTQGDKNLAAQLLGIAARTIYRKLDRDEEGRLLVPPEGGGEGPE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
SPLVLVVDDESPNLESLGKIFEREGWRVALAASGLAALELLRRERAAVVVTDLMMPGMS
CCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHEEEHHHHCCCCC
GDELLRAVKAVSPESEVVVMTAYGTVEVAVAAMKQGAYDFITKPVKRHAIVKTVRQALER
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ASLVAENRALKARLAELAPGGAGALLGDAPAFRATLEILRQAAPTQATVLLLGESGTGKE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHH
LAARLVHDLSPRAAGPFVPIHCAAIPETLLESELFGHEKGAFTGAVARKDGRFERAQGGT
HHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCE
LFLDEIGEMSPAVQVKLLRFLQDGVLERVGGNEPVRVDVRVVAATNKDLAAEVKAGRFRE
EEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHH
DLFYRLDVVRVRLPPLRERREDVPLLAMAFLRRMAERNGKPLAGFTSGAMAALERYAWPG
HHHHHHHHHEECCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
NVRELQHAIERAVVLTRADVVEVGDLPEAIRAAGPAVPEPAGAAGAPVLTVPLGTPMEEI
CHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHH
ERRVIRETLRHTQGDKNLAAQLLGIAARTIYRKLDRDEEGRLLVPPEGGGEGPE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]