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The map label for this gene is yhdR [H]

Identifier: 220915681

GI number: 220915681

Start: 640880

End: 642076

Strand: Direct

Name: yhdR [H]

Synonym: A2cp1_0562

Alternate gene names: 220915681

Gene position: 640880-642076 (Clockwise)

Preceding gene: 220915680

Following gene: 220915683

Centisome position: 12.74

GC content: 74.52

Gene sequence:

>1197_bases
ATGGACGTGGTCACCCGGCAGATCCGCAGCGAGATGGAGGGCGCCTCCTGGATCCGGCGCATGTTCGACGCCGGCCTGGA
GCTGAAGCAGCGCATCGGCGCGGACCAGGTGTTCGACTTCAGCCTGGGCAACCCGGACGTCCCGCCGCCGGCCGCGGCCG
CCGCCGCGCTGCGCGACCTCGCCGGGAAGGTCACCGCGCCCATGGGGCTCGGCTACTGCCCGAACGCCGGGCTGCCCTCG
GTGCGCGCCGCGCTGGCGCGCCGGCTCGCGGCCGAGCAGCAGGCGCCGGTCGAGGCGCGCCACCTGGTGCTCACCTGCGG
CGCCGCCGGCGGGCTGGTCACGTTCTTCCGCGCGGTGCTGGAGCCGGGCGACGAGGTGCTCTGCTTCGCGCCGTACTTCG
TGGAGTACGGCGCCTACGCCGGCCACTTCGGCGGCGTGCTCCGGGCGGTGCCGTCGATCGTCCCGGACTTCACGCCCGAC
CTCGCCGCGCTCGAGGCGGCCATCGGCCCGCGCACGCGCGTCGTGCTGGTCAACTCGCCCAACAACCCGACCGGCCGCAT
CTACGACGCCGCCACGATGCAGGCGCTCGGGGCGCTGCTCTCGCGCGTCAACCAGGGGCGCGAGCGGCCGGTGTTCCTCG
TCTCCGACGAGCCGTACCGCCGGCTCGCCTACGGCGGCGCGGCGGTGCCGGCGATCCTCCCGCTCACCCCGTTCTCGCTG
GTGGTGGGCTCGTTCTCGAAGAGCCTGTCGCTCGCCGGCGAGCGCGTGGGTTACCTGCTGGTGAACCCCGCCATGCCCGA
CGCGCAGGTGCTGGTGGACGCGCTCACGCTCACGAACCGCACGCTCGGCTTCGTGAACGCGCCGGTGGTGGGGCAGCGGC
TGGTGGAGGCGCTGGTGGACGAGAGCGTGGACGTGGGCGTCTACGACCGCCGCCGCCGGGCCATGGCCGAGGCGCTCACC
GGGGCCGGGATCCCGTTCCACCTGCCCGAGGGCGCGTTCTACTTCTTCCCCGAGGTGCCGGGCGGCGACGACCAGGCGTT
CGTGCGGCTCCTGCTCGAGGAGAACATCCTGGCCGTGCCCGGGCGCGGCTTCGGGATGCCCGGGTACATGCGCCTCACCT
TCTGCGTGGACGAGCAGGTGATCCGTCGCGCGGCCCCGGGCTTCGCGCGGGCTGCCCGGAAGGCGCGCGGCGGCTAG

Upstream 100 bases:

>100_bases
GCCGCGCCCGGCCCGTGACCGCCCCTCGCCGCGCCTGCGCCGCCCCGCCTCGCCCGGCCGCCGGATGGTGTAGAACGGAC
GGCCCGGCACGGAGGCGAAC

Downstream 100 bases:

>100_bases
TCCCCGGCGGGCGCCTCCGAGGTCCAGCCCTCGGAGATCCAGCCGCGGTGCGCGTGCCGGAGCAGCGCCGCGTGCTGCCG
GCGCGCCGCGAGCAGCCGCG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDVVTRQIRSEMEGASWIRRMFDAGLELKQRIGADQVFDFSLGNPDVPPPAAAAAALRDLAGKVTAPMGLGYCPNAGLPS
VRAALARRLAAEQQAPVEARHLVLTCGAAGGLVTFFRAVLEPGDEVLCFAPYFVEYGAYAGHFGGVLRAVPSIVPDFTPD
LAALEAAIGPRTRVVLVNSPNNPTGRIYDAATMQALGALLSRVNQGRERPVFLVSDEPYRRLAYGGAAVPAILPLTPFSL
VVGSFSKSLSLAGERVGYLLVNPAMPDAQVLVDALTLTNRTLGFVNAPVVGQRLVEALVDESVDVGVYDRRRRAMAEALT
GAGIPFHLPEGAFYFFPEVPGGDDQAFVRLLLEENILAVPGRGFGMPGYMRLTFCVDEQVIRRAAPGFARAARKARGG

Sequences:

>Translated_398_residues
MDVVTRQIRSEMEGASWIRRMFDAGLELKQRIGADQVFDFSLGNPDVPPPAAAAAALRDLAGKVTAPMGLGYCPNAGLPS
VRAALARRLAAEQQAPVEARHLVLTCGAAGGLVTFFRAVLEPGDEVLCFAPYFVEYGAYAGHFGGVLRAVPSIVPDFTPD
LAALEAAIGPRTRVVLVNSPNNPTGRIYDAATMQALGALLSRVNQGRERPVFLVSDEPYRRLAYGGAAVPAILPLTPFSL
VVGSFSKSLSLAGERVGYLLVNPAMPDAQVLVDALTLTNRTLGFVNAPVVGQRLVEALVDESVDVGVYDRRRRAMAEALT
GAGIPFHLPEGAFYFFPEVPGGDDQAFVRLLLEENILAVPGRGFGMPGYMRLTFCVDEQVIRRAAPGFARAARKARGG
>Mature_398_residues
MDVVTRQIRSEMEGASWIRRMFDAGLELKQRIGADQVFDFSLGNPDVPPPAAAAAALRDLAGKVTAPMGLGYCPNAGLPS
VRAALARRLAAEQQAPVEARHLVLTCGAAGGLVTFFRAVLEPGDEVLCFAPYFVEYGAYAGHFGGVLRAVPSIVPDFTPD
LAALEAAIGPRTRVVLVNSPNNPTGRIYDAATMQALGALLSRVNQGRERPVFLVSDEPYRRLAYGGAAVPAILPLTPFSL
VVGSFSKSLSLAGERVGYLLVNPAMPDAQVLVDALTLTNRTLGFVNAPVVGQRLVEALVDESVDVGVYDRRRRAMAEALT
GAGIPFHLPEGAFYFFPEVPGGDDQAFVRLLLEENILAVPGRGFGMPGYMRLTFCVDEQVIRRAAPGFARAARKARGG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=380, Percent_Identity=23.1578947368421, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI56713254, Length=380, Percent_Identity=23.1578947368421, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI95147551, Length=417, Percent_Identity=23.021582733813, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169881279, Length=417, Percent_Identity=23.021582733813, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4507369, Length=379, Percent_Identity=23.2189973614776, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=355, Percent_Identity=27.6056338028169, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=26.1096605744125, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=27.4193548387097, Blast_Score=98, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=25, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=230, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=232, Percent_Identity=25.4310344827586, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=232, Percent_Identity=25.4310344827586, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=375, Percent_Identity=24, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI18859735, Length=342, Percent_Identity=25.7309941520468, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573069, Length=231, Percent_Identity=26.4069264069264, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646114, Length=231, Percent_Identity=26.4069264069264, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573067, Length=231, Percent_Identity=26.4069264069264, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573065, Length=231, Percent_Identity=26.4069264069264, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42434; Mature: 42434

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVTRQIRSEMEGASWIRRMFDAGLELKQRIGADQVFDFSLGNPDVPPPAAAAAALRDL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHH
AGKVTAPMGLGYCPNAGLPSVRAALARRLAAEQQAPVEARHLVLTCGAAGGLVTFFRAVL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
EPGDEVLCFAPYFVEYGAYAGHFGGVLRAVPSIVPDFTPDLAALEAAIGPRTRVVLVNSP
CCCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECC
NNPTGRIYDAATMQALGALLSRVNQGRERPVFLVSDEPYRRLAYGGAAVPAILPLTPFSL
CCCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCHHHHHHCCCHHHH
VVGSFSKSLSLAGERVGYLLVNPAMPDAQVLVDALTLTNRTLGFVNAPVVGQRLVEALVD
HHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
ESVDVGVYDRRRRAMAEALTGAGIPFHLPEGAFYFFPEVPGGDDQAFVRLLLEENILAVP
CCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCEEECC
GRGFGMPGYMRLTFCVDEQVIRRAAPGFARAARKARGG
CCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MDVVTRQIRSEMEGASWIRRMFDAGLELKQRIGADQVFDFSLGNPDVPPPAAAAAALRDL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHH
AGKVTAPMGLGYCPNAGLPSVRAALARRLAAEQQAPVEARHLVLTCGAAGGLVTFFRAVL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
EPGDEVLCFAPYFVEYGAYAGHFGGVLRAVPSIVPDFTPDLAALEAAIGPRTRVVLVNSP
CCCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECC
NNPTGRIYDAATMQALGALLSRVNQGRERPVFLVSDEPYRRLAYGGAAVPAILPLTPFSL
CCCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCHHHHHHCCCHHHH
VVGSFSKSLSLAGERVGYLLVNPAMPDAQVLVDALTLTNRTLGFVNAPVVGQRLVEALVD
HHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
ESVDVGVYDRRRRAMAEALTGAGIPFHLPEGAFYFFPEVPGGDDQAFVRLLLEENILAVP
CCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCEEECC
GRGFGMPGYMRLTFCVDEQVIRRAAPGFARAARKARGG
CCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]