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The map label for this gene is hypE [C]

Identifier: 220915620

GI number: 220915620

Start: 575609

End: 576634

Strand: Reverse

Name: hypE [C]

Synonym: A2cp1_0501

Alternate gene names: 220915620

Gene position: 576634-575609 (Counterclockwise)

Preceding gene: 220915621

Following gene: 220915619

Centisome position: 11.47

GC content: 73.59

Gene sequence:

>1026_bases
ATGGACACGAAGGTGCAGCAGAAGATCGGCCTGAAGCACGGCTCCGGCGGGCGCGCCATGCGCCAGCTCATCGAGGACGT
GTTCCTCTCGCTGGCCTCGCCGGTGGACGGCATCGGCCTCTCGGCGCTGGACGACGGCGCGGCCATCCGCGTGGGCGACC
GCTGGCTGGTGATCACCACCGACTCTCACGTGGTGCACCCCATCTTCTTCCCGGGCGGCGACATCGGCCGGATCAGCGTC
TCGGGCACGGTGAACGACCTCGCCATGATGGGCGCCACCGAGCCGGTGGGGCTCACCTGCGCGGTGATCATCGAGGAGGG
CTTCCCGCGCGCCGACCTGGAGCGGGTGGTGGCCTCGATGCGCGAGACGGCGAAGGAGGCCGGCGCGCCGTTCGTCACCG
GCGACACCAAGGTGATGGGCAAGGGCCAGGTGGACGGCCTCCTGCTCAACACCACCGGCGTGGCGCTGGCGGACCGGGTG
GTCTCGGACGCCGGGCTGCGCGCCGGCGACCTGCTCGTCGTCACCGGCTCGATCGGCGACCACGGCATGGCCGTGATGGC
GCGCCGGCACGATCTGCGCCTCGAGGGCGACCTCCGCTCCGACGTCGCGCCCATCAACGGCCTGGTGCGCGCGGCGCTCG
CCGCCGGCGGTGAGGACGTGGTCGCGATGAAGGACCCGACCCGCGGCGGCGTGGCGGGCGTGCTGCACGAGATGGCGGCG
AAGGGCGGCGTCGGCATCGTGGTGGACGAGCCGTCGCTGCCGGTGAACGACGAGGTGCGCGCCGCCGGCGAGATGATCGG
CATCGACCCGCTGCTCGTCGCGAACGAGGGCAAGGCGGTGATCGGCGTGCGAGCCCGCTCGGCCGACAAGGTGCTGGCGG
CGCTGCGGGCCCACCCGCTCGGCGCGCGCGCCACCGTGTTCGCGCGGGCCATCGCCGAGCGGCCCGGCGCGGTGATCCTC
GACACCGGCTTCGGCAGGCGGATGCTGGCCGAGCCCGAGGGGGAGCTCCTGCCGCGCATCTGCTAG

Upstream 100 bases:

>100_bases
GGGGCGTGCATGGTGTCGTCGGAGGGGCAGTGCCGGATCTGGCACACGTACGGCGGCGTGCCCGATCTGCGCAAGGTCGG
CTAGGAAGGCGCGGAGACCC

Downstream 100 bases:

>100_bases
GCAGGTCGAGCCGCATGCACGAGTATTCCCTGGTGGAGGCGCTGGTCCGGCGCGTGGAGCAGGAGGCGCGGCGGCGCGAG
GCGCTCGCGATCCGCGGGCT

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MDTKVQQKIGLKHGSGGRAMRQLIEDVFLSLASPVDGIGLSALDDGAAIRVGDRWLVITTDSHVVHPIFFPGGDIGRISV
SGTVNDLAMMGATEPVGLTCAVIIEEGFPRADLERVVASMRETAKEAGAPFVTGDTKVMGKGQVDGLLLNTTGVALADRV
VSDAGLRAGDLLVVTGSIGDHGMAVMARRHDLRLEGDLRSDVAPINGLVRAALAAGGEDVVAMKDPTRGGVAGVLHEMAA
KGGVGIVVDEPSLPVNDEVRAAGEMIGIDPLLVANEGKAVIGVRARSADKVLAALRAHPLGARATVFARAIAERPGAVIL
DTGFGRRMLAEPEGELLPRIC

Sequences:

>Translated_341_residues
MDTKVQQKIGLKHGSGGRAMRQLIEDVFLSLASPVDGIGLSALDDGAAIRVGDRWLVITTDSHVVHPIFFPGGDIGRISV
SGTVNDLAMMGATEPVGLTCAVIIEEGFPRADLERVVASMRETAKEAGAPFVTGDTKVMGKGQVDGLLLNTTGVALADRV
VSDAGLRAGDLLVVTGSIGDHGMAVMARRHDLRLEGDLRSDVAPINGLVRAALAAGGEDVVAMKDPTRGGVAGVLHEMAA
KGGVGIVVDEPSLPVNDEVRAAGEMIGIDPLLVANEGKAVIGVRARSADKVLAALRAHPLGARATVFARAIAERPGAVIL
DTGFGRRMLAEPEGELLPRIC
>Mature_341_residues
MDTKVQQKIGLKHGSGGRAMRQLIEDVFLSLASPVDGIGLSALDDGAAIRVGDRWLVITTDSHVVHPIFFPGGDIGRISV
SGTVNDLAMMGATEPVGLTCAVIIEEGFPRADLERVVASMRETAKEAGAPFVTGDTKVMGKGQVDGLLLNTTGVALADRV
VSDAGLRAGDLLVVTGSIGDHGMAVMARRHDLRLEGDLRSDVAPINGLVRAALAAGGEDVVAMKDPTRGGVAGVLHEMAA
KGGVGIVVDEPSLPVNDEVRAAGEMIGIDPLLVANEGKAVIGVRARSADKVLAALRAHPLGARATVFARAIAERPGAVIL
DTGFGRRMLAEPEGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=340, Percent_Identity=44.4117647058823, Blast_Score=248, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35268; Mature: 35268

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKVQQKIGLKHGSGGRAMRQLIEDVFLSLASPVDGIGLSALDDGAAIRVGDRWLVITT
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCEEEEEEE
DSHVVHPIFFPGGDIGRISVSGTVNDLAMMGATEPVGLTCAVIIEEGFPRADLERVVASM
CCCEEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
RETAKEAGAPFVTGDTKVMGKGQVDGLLLNTTGVALADRVVSDAGLRAGDLLVVTGSIGD
HHHHHHHCCCEEECCCEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCC
HGMAVMARRHDLRLEGDLRSDVAPINGLVRAALAAGGEDVVAMKDPTRGGVAGVLHEMAA
CCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
KGGVGIVVDEPSLPVNDEVRAAGEMIGIDPLLVANEGKAVIGVRARSADKVLAALRAHPL
CCCEEEEECCCCCCCCCHHHHCCCEECCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCC
GARATVFARAIAERPGAVILDTGFGRRMLAEPEGELLPRIC
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTKVQQKIGLKHGSGGRAMRQLIEDVFLSLASPVDGIGLSALDDGAAIRVGDRWLVITT
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCEEEEEEE
DSHVVHPIFFPGGDIGRISVSGTVNDLAMMGATEPVGLTCAVIIEEGFPRADLERVVASM
CCCEEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
RETAKEAGAPFVTGDTKVMGKGQVDGLLLNTTGVALADRVVSDAGLRAGDLLVVTGSIGD
HHHHHHHCCCEEECCCEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCC
HGMAVMARRHDLRLEGDLRSDVAPINGLVRAALAAGGEDVVAMKDPTRGGVAGVLHEMAA
CCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
KGGVGIVVDEPSLPVNDEVRAAGEMIGIDPLLVANEGKAVIGVRARSADKVLAALRAHPL
CCCEEEEECCCCCCCCCHHHHCCCEECCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCC
GARATVFARAIAERPGAVILDTGFGRRMLAEPEGELLPRIC
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]