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The map label for this gene is selA [H]

Identifier: 220915560

GI number: 220915560

Start: 498832

End: 500307

Strand: Reverse

Name: selA [H]

Synonym: A2cp1_0441

Alternate gene names: 220915560

Gene position: 500307-498832 (Counterclockwise)

Preceding gene: 220915564

Following gene: 220915557

Centisome position: 9.95

GC content: 77.57

Gene sequence:

>1476_bases
ATGACCACTCCAAAATTCGCCCCCGGGCCCGCCGGCGCGGCCTTGCGAGGGCTCCCGCGGACGGATCGGCTGGTGGAGGC
GGCGGATCAGGCCGGCATGGTCGAGAAGCTCGGGCACGGCGCGGTCCTCGAGGCCGTCCGGGCCGAGCTCGACCGCCACC
GGGCGGCGGTGCTGGCGGGGGACCCCTGCCCCTCCCCCGAGGCGATCGAGGCAGGGCTGCTGGACCGGCTCCGCGAGGAC
GCCCGCGGGTCGCTCCGGCCGGTGGTCAACGCCACCGGCGTCGTGATCCACACCAACCTGGGTCGGGCGCCGCTGTCCGA
TGACGCCATCGCGGCCATGGGCCGGGCGGCCCGGGGCTACACCAACCTCGAGTACGACCTGGTGGCCGGCGAGCGGGGCG
ACCGGTACGGTCACGCCGAGGCGCCGCTGTGCCGGCTGACCGGCGCCGAGGCGGCGGTGGCGGTGAACAACAACGCCTCG
GCGGTCATGCTCGCGCTCGCCGCGCTGATGGACGCGCCGCCGGATCGGTCGGGCGGCGGGGAGGCGGGGGTGCGCCCGCT
GGCCGCACCCGGCCGCGGCGAGGCGGAGCCGGGCCTCCCCGAGGTGATCGTGTCCCGCGGGCAGCTCGTCGAGATCGGCG
GCGGCTTCCGCATCCCGGACGTGCTGCGCCGCTCCGGGGCCGCGCTCGTCGAGGTCGGGACCACGAACCGCACCTACCTG
CGCGATCACGAGGCGGCGGTCGGCCCGCGCACGCGCATCCTGCTGGCGGTGCACCGGTCCAACTTCCGGCTGTCCGGGTT
CGTCCACGACACGCCGCTCGAGGAGCTGGTGGACCTGGGCCGCCGTCGCGCGCTGTGGGTGGTGGACGACCTGGGCTCGG
GCACGCTCCTCGAGACGGCGCCGTTCGGCCTGGGGATCGAGCCCACCGTGCAGGAGCGGATCCGCGCCGGCGCGGACCTG
GTGTGCTTCTCCGGCGACAAGCTCCTGGGCGGCCCGCAGTCCGGGATCCTGTGCGGCACGCGCGAGGCGATCGCGCGCGT
GAAGCGCCACCCGCTCATGCGCGCGCTCCGGGTGGACAAGGTGACGCTCGCGGCGCTCTCGGCCACGCTCGCGCACTACG
AGCGCGGCGAGGCGCTCGAGAAGGTGCCGGTGTGGCGCGCCATCGCGGCGGCGCCGGAGGCGCTCGAGGCGCGGGCGCGC
GGCTGGCTCGCGGTGCTGGGCGCCGCCGGCGCCGGCTGCGCGGTGCGCCCGAGCCGCTCCGCGGTGGGCGGCGGCTCGCT
GCCCGAGGTCACCCTCCCCACCTCCGTCCTCGCCCTCCCCGGCCCGCCGGACGCGCTCGCCGCCCGGCTGCGCCGCGGGG
AGCCGCCGGTGGTCGGCCGCATCGAGGAGGATCGCGTGGTGCTCGACCCGCGGACCGTGCTGCCGGCCGAGGACGAGGCC
CTGGTCGCGGCGGTGCGGGCCGCGCTGGCCGTCTGA

Upstream 100 bases:

>100_bases
GAGGGTACGATCGAGGGCATAGAGTGGGGCGAAGGATTACCTTCATAGAGCCGCTCTAGCAAGGGTCTTGTCGGCCGAAA
ACCTCCCGGAGCATGCGGAC

Downstream 100 bases:

>100_bases
AGCCGGCTGCCCTCAAACATTGAATCTGTAGCCGATGCCGCGGACCGTCTCGAGGTGGCGCGGCTGCTCGGCGTCGTCGC
CGATGTGGGCGCGGAGCCGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTTPKFAPGPAGAALRGLPRTDRLVEAADQAGMVEKLGHGAVLEAVRAELDRHRAAVLAGDPCPSPEAIEAGLLDRLRED
ARGSLRPVVNATGVVIHTNLGRAPLSDDAIAAMGRAARGYTNLEYDLVAGERGDRYGHAEAPLCRLTGAEAAVAVNNNAS
AVMLALAALMDAPPDRSGGGEAGVRPLAAPGRGEAEPGLPEVIVSRGQLVEIGGGFRIPDVLRRSGAALVEVGTTNRTYL
RDHEAAVGPRTRILLAVHRSNFRLSGFVHDTPLEELVDLGRRRALWVVDDLGSGTLLETAPFGLGIEPTVQERIRAGADL
VCFSGDKLLGGPQSGILCGTREAIARVKRHPLMRALRVDKVTLAALSATLAHYERGEALEKVPVWRAIAAAPEALEARAR
GWLAVLGAAGAGCAVRPSRSAVGGGSLPEVTLPTSVLALPGPPDALAARLRRGEPPVVGRIEEDRVVLDPRTVLPAEDEA
LVAAVRAALAV

Sequences:

>Translated_491_residues
MTTPKFAPGPAGAALRGLPRTDRLVEAADQAGMVEKLGHGAVLEAVRAELDRHRAAVLAGDPCPSPEAIEAGLLDRLRED
ARGSLRPVVNATGVVIHTNLGRAPLSDDAIAAMGRAARGYTNLEYDLVAGERGDRYGHAEAPLCRLTGAEAAVAVNNNAS
AVMLALAALMDAPPDRSGGGEAGVRPLAAPGRGEAEPGLPEVIVSRGQLVEIGGGFRIPDVLRRSGAALVEVGTTNRTYL
RDHEAAVGPRTRILLAVHRSNFRLSGFVHDTPLEELVDLGRRRALWVVDDLGSGTLLETAPFGLGIEPTVQERIRAGADL
VCFSGDKLLGGPQSGILCGTREAIARVKRHPLMRALRVDKVTLAALSATLAHYERGEALEKVPVWRAIAAAPEALEARAR
GWLAVLGAAGAGCAVRPSRSAVGGGSLPEVTLPTSVLALPGPPDALAARLRRGEPPVVGRIEEDRVVLDPRTVLPAEDEA
LVAAVRAALAV
>Mature_490_residues
TTPKFAPGPAGAALRGLPRTDRLVEAADQAGMVEKLGHGAVLEAVRAELDRHRAAVLAGDPCPSPEAIEAGLLDRLREDA
RGSLRPVVNATGVVIHTNLGRAPLSDDAIAAMGRAARGYTNLEYDLVAGERGDRYGHAEAPLCRLTGAEAAVAVNNNASA
VMLALAALMDAPPDRSGGGEAGVRPLAAPGRGEAEPGLPEVIVSRGQLVEIGGGFRIPDVLRRSGAALVEVGTTNRTYLR
DHEAAVGPRTRILLAVHRSNFRLSGFVHDTPLEELVDLGRRRALWVVDDLGSGTLLETAPFGLGIEPTVQERIRAGADLV
CFSGDKLLGGPQSGILCGTREAIARVKRHPLMRALRVDKVTLAALSATLAHYERGEALEKVPVWRAIAAAPEALEARARG
WLAVLGAAGAGCAVRPSRSAVGGGSLPEVTLPTSVLALPGPPDALAARLRRGEPPVVGRIEEDRVVLDPRTVLPAEDEAL
VAAVRAALAV

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=474, Percent_Identity=44.3037974683544, Blast_Score=297, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 51187; Mature: 51056

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPKFAPGPAGAALRGLPRTDRLVEAADQAGMVEKLGHGAVLEAVRAELDRHRAAVLAG
CCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCEEEEEC
DPCPSPEAIEAGLLDRLREDARGSLRPVVNATGVVIHTNLGRAPLSDDAIAAMGRAARGY
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCC
TNLEYDLVAGERGDRYGHAEAPLCRLTGAEAAVAVNNNASAVMLALAALMDAPPDRSGGG
CCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
EAGVRPLAAPGRGEAEPGLPEVIVSRGQLVEIGGGFRIPDVLRRSGAALVEVGTTNRTYL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHCCCEEEEECCCCCCEE
RDHEAAVGPRTRILLAVHRSNFRLSGFVHDTPLEELVDLGRRRALWVVDDLGSGTLLETA
ECCCCCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHCCCCEEEEEEECCCCCCEEECC
PFGLGIEPTVQERIRAGADLVCFSGDKLLGGPQSGILCGTREAIARVKRHPLMRALRVDK
CCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
VTLAALSATLAHYERGEALEKVPVWRAIAAAPEALEARARGWLAVLGAAGAGCAVRPSRS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHCCEEEEEECCCCCCEECCCCC
AVGGGSLPEVTLPTSVLALPGPPDALAARLRRGEPPVVGRIEEDRVVLDPRTVLPAEDEA
CCCCCCCCCEECCCEEEECCCCHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCCCHH
LVAAVRAALAV
HHHHHHHHHCC
>Mature Secondary Structure 
TTPKFAPGPAGAALRGLPRTDRLVEAADQAGMVEKLGHGAVLEAVRAELDRHRAAVLAG
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCEEEEEC
DPCPSPEAIEAGLLDRLREDARGSLRPVVNATGVVIHTNLGRAPLSDDAIAAMGRAARGY
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCC
TNLEYDLVAGERGDRYGHAEAPLCRLTGAEAAVAVNNNASAVMLALAALMDAPPDRSGGG
CCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
EAGVRPLAAPGRGEAEPGLPEVIVSRGQLVEIGGGFRIPDVLRRSGAALVEVGTTNRTYL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHCCCEEEEECCCCCCEE
RDHEAAVGPRTRILLAVHRSNFRLSGFVHDTPLEELVDLGRRRALWVVDDLGSGTLLETA
ECCCCCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHCCCCEEEEEEECCCCCCEEECC
PFGLGIEPTVQERIRAGADLVCFSGDKLLGGPQSGILCGTREAIARVKRHPLMRALRVDK
CCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
VTLAALSATLAHYERGEALEKVPVWRAIAAAPEALEARARGWLAVLGAAGAGCAVRPSRS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHCCEEEEEECCCCCCEECCCCC
AVGGGSLPEVTLPTSVLALPGPPDALAARLRRGEPPVVGRIEEDRVVLDPRTVLPAEDEA
CCCCCCCCCEECCCEEEECCCCHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCCCHH
LVAAVRAALAV
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA