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The map label for this gene is stc [H]

Identifier: 220915506

GI number: 220915506

Start: 433458

End: 435416

Strand: Reverse

Name: stc [H]

Synonym: A2cp1_0387

Alternate gene names: 220915506

Gene position: 435416-433458 (Counterclockwise)

Preceding gene: 220915511

Following gene: 220915505

Centisome position: 8.66

GC content: 75.45

Gene sequence:

>1959_bases
GTGACCCCCGCCGACCGCCGCCCCATCGTCTGGGCGTTCAGCACGAGCCGACTCCGGCACGTGTTCGAGAGCGTCGCGCC
CTTGATGGCGGACGTGGCCGAGGTCCGGGTCTTCGACAAGGGGTTCGAGGAGGCGCTCCAGGTCGCGCGCGAGCTCCGGC
AGGCCGGCGAGGAGGTGGACGCGTTCGTGGCGGCCGGCACCAACGGCGCCTACCTGCGCGACCACGCGGACGTGCCGGTG
GTGGTGGTGACCGCCTCGACCGTGGACGCGCTCCAGGCGCTGGTGCAGGCGCGCAAGCTCTCGAAGCGCATCGGCGTGGT
GAACTTCCGGCGCACGGTGGCGGGCCTCGAGGGCGTGCACCTCATCGACGACACCGTCATCGAGCAGCGGCCCTACGTGA
CGCCGGAGGAAGGGCAGGCCGCGGTGGACGACCTCTCCGCGCGCGGCTTCAAGGTCATCGTCGGCCCGGGGCCCATCTGC
TCGGTCGCGGAGCGCTCCGGCCTGCGCGCCGTGCTGCTGTACGGCCAGGACTCGCTGGAAGAGGCGATCCGCCAGGCCGC
CGAGGTGGCGCGCATCGCGCGCGTCGAGGGCTCGCGGCGCACACACCTCCAGGCGATGTTCCAGCACCTCGAGGTCGGGG
TGGTGGCGGTGGACACCGAGGAGCGCATCCAGGCCATCAACCCGGCGCTGCAGCGGCTGCTCGGCGTCACCGCGGCCGAG
GTGCAGGGGCGCAAGCTCTCCGCGGTCGCGCCCGAGCTGGCCATGGGCCCGGTGCTGGAGGGCGGCCCGCCGGAGGTCGA
GGCGGTGCAGCGCATCGGCGTCGCCGCCGCGGTGGTGAGCCGGTTCCCGCTGCACGAGCACGGCGTCCTGCGCGGCGCGG
TGCTCACCTGCCAGCCCGCCGCGATGGTCCAGCGGCTCGAGCGCGGGCTCCGCTCCACGCACCGCCCGCCGCGGTTCGTG
GCGCGGTACGCGCTCTCCGGCCTGGTGGGCGAGTCGCCGGCGATGGTCCGGCTGCGCGAGCTCGCCGGCCGCTACGCGCG
CACCGACGCCACCGTGCTCATCACCGGCGAGAGCGGCACCGGCAAGGAGATGGTGGCGCAGGGCATCCACGGCGCGAGCC
GCCGGCGCGACCGGCCGTTCGTGGCGGTGAACTGCGCCGCGTTCCCGGAGACGCTGCTCGAGGCCGAGCTGTTCGGCTAC
GAGGAGGGCGCGTTCACCGGCTCGCGGCGCGGCGGGCGCCCCGGCCTGTTCGAGGCGGCGCACACCGGCACGCTGTTCCT
CGACGAGATCGGCGACGTGCCGGTCACGCTGCAGACGCGGCTCCTGCGCGTCCTGCAGGAGCGGCAGGTGCTCCGGCTCG
GCAGCAACGATCCCACCCCGGTGGACGTGCGCGTCATCGCCGCGACGCACCGCGACCTCCGGCAGGCCATCGCGCGCGGC
GAGTTCCGCGAGGACCTCTACTACCGCCTCGACATCCTCCCGCTGCACCTGCCGCCGCTGCGCGAGCGGGGCGAGGCGGA
CGTCGAGCTCATCGCCTCCGACCTGCTGAAGCGCGCCCTCCTCCGCCATGGCGCCGCCGACGCGCACCGGCGCGCGCTCT
CCATGGTGCTGCCGCGGCTGCGCGGACACGCCTGGCCCGGGAACGTGCGCGAGCTCGAGAACGTGCTCGAGCGCGTGGCG
GTGCTGTTCGCGGACCGCGACCCGCGCGCGCGCGTGACCGAGGAGGAGCTCGCCGCGGTGATGCCGGAGGTCGCGGATCC
GACCGCCCGCGCCGCCGCGCCCACCGCTCCCTCCGCGGTCGCCCCGCCCATCGACCTCCGCCTCGCCCGCGCCGCCCAGG
AGCGGGTCCTCATCGAGCGGACCGTGGCCGAGTGCGGCGGCAACCAGGCCGAGGCCGCCCGCCGGCTCGGCATCGGGCGG
ACCACGCTGTACCGGAAGCTCGGGAGGGTCAGGGCGTAG

Upstream 100 bases:

>100_bases
TCCGTTCCGGTTTCGGTACAGTACCGGTACACCAGGCCCGCCTCTCCCCGAACCCAGAGTCGTTTGCTCCTGACCCAGAG
TCGTTTCGCGAGGAGCCGTC

Downstream 100 bases:

>100_bases
ACCTCGGTCGCCCCCTCCCGAGCGCGCCGCCGATCTCCTTGACTCCCGCCCGCCTTCACGGCAAAAACGGGGTCGCGACG
CGGGAATAGCTCAGTTGGTA

Product: proprionate catabolism activator, Fis family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MTPADRRPIVWAFSTSRLRHVFESVAPLMADVAEVRVFDKGFEEALQVARELRQAGEEVDAFVAAGTNGAYLRDHADVPV
VVVTASTVDALQALVQARKLSKRIGVVNFRRTVAGLEGVHLIDDTVIEQRPYVTPEEGQAAVDDLSARGFKVIVGPGPIC
SVAERSGLRAVLLYGQDSLEEAIRQAAEVARIARVEGSRRTHLQAMFQHLEVGVVAVDTEERIQAINPALQRLLGVTAAE
VQGRKLSAVAPELAMGPVLEGGPPEVEAVQRIGVAAAVVSRFPLHEHGVLRGAVLTCQPAAMVQRLERGLRSTHRPPRFV
ARYALSGLVGESPAMVRLRELAGRYARTDATVLITGESGTGKEMVAQGIHGASRRRDRPFVAVNCAAFPETLLEAELFGY
EEGAFTGSRRGGRPGLFEAAHTGTLFLDEIGDVPVTLQTRLLRVLQERQVLRLGSNDPTPVDVRVIAATHRDLRQAIARG
EFREDLYYRLDILPLHLPPLRERGEADVELIASDLLKRALLRHGAADAHRRALSMVLPRLRGHAWPGNVRELENVLERVA
VLFADRDPRARVTEEELAAVMPEVADPTARAAAPTAPSAVAPPIDLRLARAAQERVLIERTVAECGGNQAEAARRLGIGR
TTLYRKLGRVRA

Sequences:

>Translated_652_residues
MTPADRRPIVWAFSTSRLRHVFESVAPLMADVAEVRVFDKGFEEALQVARELRQAGEEVDAFVAAGTNGAYLRDHADVPV
VVVTASTVDALQALVQARKLSKRIGVVNFRRTVAGLEGVHLIDDTVIEQRPYVTPEEGQAAVDDLSARGFKVIVGPGPIC
SVAERSGLRAVLLYGQDSLEEAIRQAAEVARIARVEGSRRTHLQAMFQHLEVGVVAVDTEERIQAINPALQRLLGVTAAE
VQGRKLSAVAPELAMGPVLEGGPPEVEAVQRIGVAAAVVSRFPLHEHGVLRGAVLTCQPAAMVQRLERGLRSTHRPPRFV
ARYALSGLVGESPAMVRLRELAGRYARTDATVLITGESGTGKEMVAQGIHGASRRRDRPFVAVNCAAFPETLLEAELFGY
EEGAFTGSRRGGRPGLFEAAHTGTLFLDEIGDVPVTLQTRLLRVLQERQVLRLGSNDPTPVDVRVIAATHRDLRQAIARG
EFREDLYYRLDILPLHLPPLRERGEADVELIASDLLKRALLRHGAADAHRRALSMVLPRLRGHAWPGNVRELENVLERVA
VLFADRDPRARVTEEELAAVMPEVADPTARAAAPTAPSAVAPPIDLRLARAAQERVLIERTVAECGGNQAEAARRLGIGR
TTLYRKLGRVRA
>Mature_651_residues
TPADRRPIVWAFSTSRLRHVFESVAPLMADVAEVRVFDKGFEEALQVARELRQAGEEVDAFVAAGTNGAYLRDHADVPVV
VVTASTVDALQALVQARKLSKRIGVVNFRRTVAGLEGVHLIDDTVIEQRPYVTPEEGQAAVDDLSARGFKVIVGPGPICS
VAERSGLRAVLLYGQDSLEEAIRQAAEVARIARVEGSRRTHLQAMFQHLEVGVVAVDTEERIQAINPALQRLLGVTAAEV
QGRKLSAVAPELAMGPVLEGGPPEVEAVQRIGVAAAVVSRFPLHEHGVLRGAVLTCQPAAMVQRLERGLRSTHRPPRFVA
RYALSGLVGESPAMVRLRELAGRYARTDATVLITGESGTGKEMVAQGIHGASRRRDRPFVAVNCAAFPETLLEAELFGYE
EGAFTGSRRGGRPGLFEAAHTGTLFLDEIGDVPVTLQTRLLRVLQERQVLRLGSNDPTPVDVRVIAATHRDLRQAIARGE
FREDLYYRLDILPLHLPPLRERGEADVELIASDLLKRALLRHGAADAHRRALSMVLPRLRGHAWPGNVRELENVLERVAV
LFADRDPRARVTEEELAAVMPEVADPTARAAAPTAPSAVAPPIDLRLARAAQERVLIERTVAECGGNQAEAARRLGIGRT
TLYRKLGRVRA

Specific function: Involved In The Transcriptional Regulation Of The Propionate Catabolism Operon. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1786524, Length=337, Percent_Identity=47.7744807121662, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1788905, Length=324, Percent_Identity=46.2962962962963, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1789233, Length=461, Percent_Identity=35.5748373101952, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1790437, Length=356, Percent_Identity=43.5393258426966, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI1788550, Length=389, Percent_Identity=39.0745501285347, Blast_Score=250, Evalue=3e-67,
Organism=Escherichia coli, GI87082117, Length=342, Percent_Identity=42.9824561403509, Blast_Score=239, Evalue=5e-64,
Organism=Escherichia coli, GI1790299, Length=360, Percent_Identity=41.9444444444444, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1789087, Length=329, Percent_Identity=44.6808510638298, Blast_Score=235, Evalue=8e-63,
Organism=Escherichia coli, GI87082152, Length=326, Percent_Identity=42.9447852760736, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=328, Percent_Identity=37.1951219512195, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI1787583, Length=358, Percent_Identity=34.0782122905028, Blast_Score=172, Evalue=8e-44,
Organism=Escherichia coli, GI87081858, Length=452, Percent_Identity=28.9823008849558, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789828, Length=315, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70967; Mature: 70836

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPADRRPIVWAFSTSRLRHVFESVAPLMADVAEVRVFDKGFEEALQVARELRQAGEEVD
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AFVAAGTNGAYLRDHADVPVVVVTASTVDALQALVQARKLSKRIGVVNFRRTVAGLEGVH
HHHEECCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
LIDDTVIEQRPYVTPEEGQAAVDDLSARGFKVIVGPGPICSVAERSGLRAVLLYGQDSLE
HHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHCCCCEEEEEECCHHHH
EAIRQAAEVARIARVEGSRRTHLQAMFQHLEVGVVAVDTEERIQAINPALQRLLGVTAAE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHCCHHHH
VQGRKLSAVAPELAMGPVLEGGPPEVEAVQRIGVAAAVVSRFPLHEHGVLRGAVLTCQPA
HCCCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEEECCHH
AMVQRLERGLRSTHRPPRFVARYALSGLVGESPAMVRLRELAGRYARTDATVLITGESGT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
GKEMVAQGIHGASRRRDRPFVAVNCAAFPETLLEAELFGYEEGAFTGSRRGGRPGLFEAA
CHHHHHHHCCCHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
HTGTLFLDEIGDVPVTLQTRLLRVLQERQVLRLGSNDPTPVDVRVIAATHRDLRQAIARG
CCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHCC
EFREDLYYRLDILPLHLPPLRERGEADVELIASDLLKRALLRHGAADAHRRALSMVLPRL
CHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGHAWPGNVRELENVLERVAVLFADRDPRARVTEEELAAVMPEVADPTARAAAPTAPSAV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHCCCCHHCCCCCCCCCC
APPIDLRLARAAQERVLIERTVAECGGNQAEAARRLGIGRTTLYRKLGRVRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TPADRRPIVWAFSTSRLRHVFESVAPLMADVAEVRVFDKGFEEALQVARELRQAGEEVD
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AFVAAGTNGAYLRDHADVPVVVVTASTVDALQALVQARKLSKRIGVVNFRRTVAGLEGVH
HHHEECCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
LIDDTVIEQRPYVTPEEGQAAVDDLSARGFKVIVGPGPICSVAERSGLRAVLLYGQDSLE
HHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHCCCCEEEEEECCHHHH
EAIRQAAEVARIARVEGSRRTHLQAMFQHLEVGVVAVDTEERIQAINPALQRLLGVTAAE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHCCHHHH
VQGRKLSAVAPELAMGPVLEGGPPEVEAVQRIGVAAAVVSRFPLHEHGVLRGAVLTCQPA
HCCCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEEECCHH
AMVQRLERGLRSTHRPPRFVARYALSGLVGESPAMVRLRELAGRYARTDATVLITGESGT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
GKEMVAQGIHGASRRRDRPFVAVNCAAFPETLLEAELFGYEEGAFTGSRRGGRPGLFEAA
CHHHHHHHCCCHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
HTGTLFLDEIGDVPVTLQTRLLRVLQERQVLRLGSNDPTPVDVRVIAATHRDLRQAIARG
CCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHCC
EFREDLYYRLDILPLHLPPLRERGEADVELIASDLLKRALLRHGAADAHRRALSMVLPRL
CHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGHAWPGNVRELENVLERVAVLFADRDPRARVTEEELAAVMPEVADPTARAAAPTAPSAV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHCCCCHHCCCCCCCCCC
APPIDLRLARAAQERVLIERTVAECGGNQAEAARRLGIGRTTLYRKLGRVRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA