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The map label for this gene is mcpA [H]

Identifier: 220915488

GI number: 220915488

Start: 414008

End: 416185

Strand: Reverse

Name: mcpA [H]

Synonym: A2cp1_0369

Alternate gene names: 220915488

Gene position: 416185-414008 (Counterclockwise)

Preceding gene: 220915489

Following gene: 220915485

Centisome position: 8.28

GC content: 76.81

Gene sequence:

>2178_bases
ATGCTCCGCTCGCTCCCGGTCTCGACGAAGATCCTCGGCTCCTCCCTGCTCGCCGCGGGCGCCACGCTCGCGGCCGGGAT
GGCCGGCTGGCTCGCCGCACGGGGCGGCCTGCCCGGCGGTGCCACCCTCGCGCTCGGCGCCTCGGCGGCGGTCGCGGCGG
TGATCGCCGCGGGCGGGCTGTTCGTCTCGCTCGTGGTCGGCCGCGCCATCCGCGCCATGCGCACCGAGTCCGCGCACGTG
CGCGACGCGGTGCGCGCCGGCATGCTCACGGTGCGCGGGGGCGAGGGGCGCATCGACCCGGAGTTCCAGCTCATCATCCG
GACCTTGAACGAGACGCTGGACGCGTTCTCGGTCCCGTTCGCCGCCACCGCGGAGGCGGTGGAGCGCATCTCGCGCGGCG
ACCTCCCCGCGCGCATCACCGCGCCGTTCGAGGGCGACTTCGACCGCCTGCGCGAGGCGGTGAATGCGGTGATCGAGGTG
GTGGAGCAGCGCAACGACGACATCCGGCGCCTGGTGGAGGCGGCCACCGCGGGCCGCCTGGACGTCCGGGCGGACGTCAC
CCGCTACCACGGGTACAACGGCGCCATGATCGGCCGGATCAACCTGCTCCTCGACACCGTGATCCGGCCGATCGAGGTCG
CCACGGACCGGGTGGTGCGCCTCGCCGCCGGCGAGGTGCCGCCCGACGTCGATCTCGCGGTGCAGGGCCGCTTCCTCGAC
CTGAAGCGAGGGGTGAACGCGCTGCTCGAGGTGGTGCGCCTGCGCAACGCGGACCTGGCGCTGCTCCTGCGCGCGGCGGC
GGAGGGGCGCCTGGACGTGCGCGCCGACCCTTCGCGCTACCCGGGCCAGAACGGCGACCTGGTGCGGGGGATGAACGCCT
TGCTCGACGCCGTGGTGGCGCCGCTCCGTGCGGCGGCGGGCGCGCTCGAGCGGCTGGCGCGCGGAGAGGCGCCCGCGCCG
ATCGAGGAGACCTATCGCGGCGAGTTCGACACGCTCCGCCGCAACGTGAACGCCTGCACGTCCGCCATCCGCGCGCTCGT
CGGCGAGGTGGACGTGGCCATCGAGGCCGGCCGCGCCGGCGACCTTGGCCGCCGGGGCGACCCGGCCCGCTGCGAGGGCG
ACTACCGCCGCGTCCTCGCAGGGGTGAACGAGATCCTGGACGCGGTCTCCGCGCCGGTTCGCGAGGCCAGCGAGGTCCTG
GCGCGGCTCGCCGCGCGCGACCTGCGAGCGCGCATGGGCGGGCGCTACCTGGGCGACCACGCGCGGCTCCAGCAGGTGGT
GAACGGCACTGCCGGCGCGCTCGACGCGGCGCTCGGCCAGGTGGTCGAGGCGGTGGGCGGGATCTCGGCGGCCGCGGCCC
AGATCGCCTCCTCGAGCCGGGCGGTGGCGGGTGGCGCCGCCGAGCAGGCCTCCGCCATCGGCCGCACCGGCGCGAGCCTC
GAGGCGGTCGCCGGGCAGGCGCGCGCCACCTCCGAGCACGCCTCCGCCGCGGACGGCCTCACCGCGGCGGCGCGCGACGC
CGCCGCCGAGGGCACCGCCACGGTGTCGCGCATGACCGCCGCCATGGCGCAGGTGCGCCTGGCGGCCGAGCAGACCGCGC
AGATCATCAAGGACATCGACGAGATCTCGTTCCAGACGAACCTGCTCGCGCTGAACGCGGCGGTGGAGGCCGCCCGCGCC
GGCGACGCCGGGCGCGGGTTCGCGGTGGTCGCCGAGGAGGTGCGCTCGCTCGCGCTCCGCTCCAAGGCGGCCGCCTCCCG
CACCGAGGCGCTCATCCACGAGTCGGTGCGCCAGGCGGCGGACGGCGACGCGATCACGCGCGCGGTCGCGGAGCGGCTCG
AGGCGATCCACGGCAGCTCGGACCGGCTCGCCGCGCTCGCGGCCGAGATCAGCGCGTCGGCGCGGGAGCAGGCCAGCGGG
GTCGCGCGGATCACCGGCACGGTGGCCGAGATCGACCGGGTCACCCAGCAGAACGCCGCCAGCGCCGAGCAGTCCTCGGC
GGCGGCGGCGGAGCTGTCGGCGCGCTCGGGCATGCTGGCCGAGCTGCTGGGAGAGTTCCGGCTGGGCGGCGCCGGCGATC
GCGCCGCGGTGAGGGCCGCGCCCCGCGCCGCGTGCGAGGCAGGCCGGGGATCGGACGACCCGACCTGCCTCGCGGCGGGT
GCTACAGGGGGAGCATGA

Upstream 100 bases:

>100_bases
GCCCGCCGCCCCGATGCCACGGCCCGCCGCCGACGCGCTGGCACGTCGGGTGCTCCGCCGCCTCCGAACGTCCACCGCGC
CCGCCTCGCCAGGTCCCGAC

Downstream 100 bases:

>100_bases
GCTTGAGGAAGACGCGATCCGCCTGCAGGCGGCTGTCGCTCGTGACGTCGTGGTGCCACATCCCGATGAACGTGCCGAAC
GGCGCCTGGTACGCGGCCTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MLRSLPVSTKILGSSLLAAGATLAAGMAGWLAARGGLPGGATLALGASAAVAAVIAAGGLFVSLVVGRAIRAMRTESAHV
RDAVRAGMLTVRGGEGRIDPEFQLIIRTLNETLDAFSVPFAATAEAVERISRGDLPARITAPFEGDFDRLREAVNAVIEV
VEQRNDDIRRLVEAATAGRLDVRADVTRYHGYNGAMIGRINLLLDTVIRPIEVATDRVVRLAAGEVPPDVDLAVQGRFLD
LKRGVNALLEVVRLRNADLALLLRAAAEGRLDVRADPSRYPGQNGDLVRGMNALLDAVVAPLRAAAGALERLARGEAPAP
IEETYRGEFDTLRRNVNACTSAIRALVGEVDVAIEAGRAGDLGRRGDPARCEGDYRRVLAGVNEILDAVSAPVREASEVL
ARLAARDLRARMGGRYLGDHARLQQVVNGTAGALDAALGQVVEAVGGISAAAAQIASSSRAVAGGAAEQASAIGRTGASL
EAVAGQARATSEHASAADGLTAAARDAAAEGTATVSRMTAAMAQVRLAAEQTAQIIKDIDEISFQTNLLALNAAVEAARA
GDAGRGFAVVAEEVRSLALRSKAAASRTEALIHESVRQAADGDAITRAVAERLEAIHGSSDRLAALAAEISASAREQASG
VARITGTVAEIDRVTQQNAASAEQSSAAAAELSARSGMLAELLGEFRLGGAGDRAAVRAAPRAACEAGRGSDDPTCLAAG
ATGGA

Sequences:

>Translated_725_residues
MLRSLPVSTKILGSSLLAAGATLAAGMAGWLAARGGLPGGATLALGASAAVAAVIAAGGLFVSLVVGRAIRAMRTESAHV
RDAVRAGMLTVRGGEGRIDPEFQLIIRTLNETLDAFSVPFAATAEAVERISRGDLPARITAPFEGDFDRLREAVNAVIEV
VEQRNDDIRRLVEAATAGRLDVRADVTRYHGYNGAMIGRINLLLDTVIRPIEVATDRVVRLAAGEVPPDVDLAVQGRFLD
LKRGVNALLEVVRLRNADLALLLRAAAEGRLDVRADPSRYPGQNGDLVRGMNALLDAVVAPLRAAAGALERLARGEAPAP
IEETYRGEFDTLRRNVNACTSAIRALVGEVDVAIEAGRAGDLGRRGDPARCEGDYRRVLAGVNEILDAVSAPVREASEVL
ARLAARDLRARMGGRYLGDHARLQQVVNGTAGALDAALGQVVEAVGGISAAAAQIASSSRAVAGGAAEQASAIGRTGASL
EAVAGQARATSEHASAADGLTAAARDAAAEGTATVSRMTAAMAQVRLAAEQTAQIIKDIDEISFQTNLLALNAAVEAARA
GDAGRGFAVVAEEVRSLALRSKAAASRTEALIHESVRQAADGDAITRAVAERLEAIHGSSDRLAALAAEISASAREQASG
VARITGTVAEIDRVTQQNAASAEQSSAAAAELSARSGMLAELLGEFRLGGAGDRAAVRAAPRAACEAGRGSDDPTCLAAG
ATGGA
>Mature_725_residues
MLRSLPVSTKILGSSLLAAGATLAAGMAGWLAARGGLPGGATLALGASAAVAAVIAAGGLFVSLVVGRAIRAMRTESAHV
RDAVRAGMLTVRGGEGRIDPEFQLIIRTLNETLDAFSVPFAATAEAVERISRGDLPARITAPFEGDFDRLREAVNAVIEV
VEQRNDDIRRLVEAATAGRLDVRADVTRYHGYNGAMIGRINLLLDTVIRPIEVATDRVVRLAAGEVPPDVDLAVQGRFLD
LKRGVNALLEVVRLRNADLALLLRAAAEGRLDVRADPSRYPGQNGDLVRGMNALLDAVVAPLRAAAGALERLARGEAPAP
IEETYRGEFDTLRRNVNACTSAIRALVGEVDVAIEAGRAGDLGRRGDPARCEGDYRRVLAGVNEILDAVSAPVREASEVL
ARLAARDLRARMGGRYLGDHARLQQVVNGTAGALDAALGQVVEAVGGISAAAAQIASSSRAVAGGAAEQASAIGRTGASL
EAVAGQARATSEHASAADGLTAAARDAAAEGTATVSRMTAAMAQVRLAAEQTAQIIKDIDEISFQTNLLALNAAVEAARA
GDAGRGFAVVAEEVRSLALRSKAAASRTEALIHESVRQAADGDAITRAVAERLEAIHGSSDRLAALAAEISASAREQASG
VARITGTVAEIDRVTQQNAASAEQSSAAAAELSARSGMLAELLGEFRLGGAGDRAAVRAAPRAACEAGRGSDDPTCLAAG
ATGGA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=34.7692307692308, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788195, Length=290, Percent_Identity=36.551724137931, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI2367378, Length=257, Percent_Identity=38.5214007782101, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI1788194, Length=236, Percent_Identity=36.864406779661, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1789453, Length=244, Percent_Identity=34.4262295081967, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74428; Mature: 74428

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSLPVSTKILGSSLLAAGATLAAGMAGWLAARGGLPGGATLALGASAAVAAVIAAGGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
FVSLVVGRAIRAMRTESAHVRDAVRAGMLTVRGGEGRIDPEFQLIIRTLNETLDAFSVPF
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCH
AATAEAVERISRGDLPARITAPFEGDFDRLREAVNAVIEVVEQRNDDIRRLVEAATAGRL
HHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
DVRADVTRYHGYNGAMIGRINLLLDTVIRPIEVATDRVVRLAAGEVPPDVDLAVQGRFLD
EEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHH
LKRGVNALLEVVRLRNADLALLLRAAAEGRLDVRADPSRYPGQNGDLVRGMNALLDAVVA
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
PLRAAAGALERLARGEAPAPIEETYRGEFDTLRRNVNACTSAIRALVGEVDVAIEAGRAG
HHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
DLGRRGDPARCEGDYRRVLAGVNEILDAVSAPVREASEVLARLAARDLRARMGGRYLGDH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ARLQQVVNGTAGALDAALGQVVEAVGGISAAAAQIASSSRAVAGGAAEQASAIGRTGASL
HHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCCH
EAVAGQARATSEHASAADGLTAAARDAAAEGTATVSRMTAAMAQVRLAAEQTAQIIKDID
HHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISFQTNLLALNAAVEAARAGDAGRGFAVVAEEVRSLALRSKAAASRTEALIHESVRQAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGDAITRAVAERLEAIHGSSDRLAALAAEISASAREQASGVARITGTVAEIDRVTQQNAA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SAEQSSAAAAELSARSGMLAELLGEFRLGGAGDRAAVRAAPRAACEAGRGSDDPTCLAAG
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHCCCCCCCCCEEECC
ATGGA
CCCCC
>Mature Secondary Structure
MLRSLPVSTKILGSSLLAAGATLAAGMAGWLAARGGLPGGATLALGASAAVAAVIAAGGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
FVSLVVGRAIRAMRTESAHVRDAVRAGMLTVRGGEGRIDPEFQLIIRTLNETLDAFSVPF
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCH
AATAEAVERISRGDLPARITAPFEGDFDRLREAVNAVIEVVEQRNDDIRRLVEAATAGRL
HHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
DVRADVTRYHGYNGAMIGRINLLLDTVIRPIEVATDRVVRLAAGEVPPDVDLAVQGRFLD
EEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHH
LKRGVNALLEVVRLRNADLALLLRAAAEGRLDVRADPSRYPGQNGDLVRGMNALLDAVVA
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
PLRAAAGALERLARGEAPAPIEETYRGEFDTLRRNVNACTSAIRALVGEVDVAIEAGRAG
HHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
DLGRRGDPARCEGDYRRVLAGVNEILDAVSAPVREASEVLARLAARDLRARMGGRYLGDH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ARLQQVVNGTAGALDAALGQVVEAVGGISAAAAQIASSSRAVAGGAAEQASAIGRTGASL
HHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCCH
EAVAGQARATSEHASAADGLTAAARDAAAEGTATVSRMTAAMAQVRLAAEQTAQIIKDID
HHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISFQTNLLALNAAVEAARAGDAGRGFAVVAEEVRSLALRSKAAASRTEALIHESVRQAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGDAITRAVAERLEAIHGSSDRLAALAAEISASAREQASGVARITGTVAEIDRVTQQNAA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SAEQSSAAAAELSARSGMLAELLGEFRLGGAGDRAAVRAAPRAACEAGRGSDDPTCLAAG
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHCCCCCCCCCEEECC
ATGGA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]