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The map label for this gene is tsf

Identifier: 220915415

GI number: 220915415

Start: 329443

End: 330102

Strand: Reverse

Name: tsf

Synonym: A2cp1_0294

Alternate gene names: 220915415

Gene position: 330102-329443 (Counterclockwise)

Preceding gene: 220915416

Following gene: 220915412

Centisome position: 6.56

GC content: 67.73

Gene sequence:

>660_bases
GTGGCCGAGATCAGCGCGAAGATGGTGCAGGAGCTCCGGGAGAAGACCGGGGCCGGGATGATGGACTGCAAGAAGGCCCT
CACCGAGGCCGGCGGCGATCTCGCCAAGGCCGAGGAGGTCCTCCGCAAGAAGGGGCTCTCCGCCGCGGCCAAGAAGACCG
GCCGCGCCGCGACCGAGGGCGCCGTCGCCAGCTACATCCACATGGGCGGCAAGATCGGCGTCCTGGTGGAGGTGAACTGC
GAGACCGACTTCGTGGCGCGCACCGAGGGCTTCCAGGGCCTGGTGAAGGAGATCGCCATGCAGGTCGCGGCCGCCTCGCC
GCGCTGGGTCCGCCGCGAGGAGGTCCCGGCCGACGTGGTCGCCAAGGAGCTGGAGATCGCGAAGGCACAGGCCCGCGAGC
AGAAGAAGCCCGAGGCCATCCTCGAGAAGATCGCCACCGGCAAGGTGGAGAAGTTCTACTCGGAGTTCTGCCTGATGGAG
CAGGCCTGGGTGAAGGACGACAAGAAGAAGATCCAGGACGTCCTCACCGACGCGGTCGCGAAGATCGGCGAGAACATCCA
GATCCGCCGCTTCGCCCGCTTCGTGCTGGGCGAGGGCCTGGAGAAGAAGCAGGAGAACCTGGCCGAGGAGGTCGCCAAGG
CGGCCGGCCTGCAGAAGTAG

Upstream 100 bases:

>100_bases
CCCCGCGCGCCGCGCGGGGTGAGCTCGTTTCCGGGGGCGGGCCCACCAGGCCCGCCCCCATCGTTTTCCGCACAGACGGA
GCACAGACAGGAGAAGGTTC

Downstream 100 bases:

>100_bases
CTCCCGCCATCCGGCGTCTGCATCCCGGGGCCCTGGTCCGCGTTCGCGGGCCGGGGCCTCGTCGTTTGCGGGGCCGGGAA
CGCGCGTCGGCGCGAGCGCC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAEISAKMVQELREKTGAGMMDCKKALTEAGGDLAKAEEVLRKKGLSAAAKKTGRAATEGAVASYIHMGGKIGVLVEVNC
ETDFVARTEGFQGLVKEIAMQVAAASPRWVRREEVPADVVAKELEIAKAQAREQKKPEAILEKIATGKVEKFYSEFCLME
QAWVKDDKKKIQDVLTDAVAKIGENIQIRRFARFVLGEGLEKKQENLAEEVAKAAGLQK

Sequences:

>Translated_219_residues
MAEISAKMVQELREKTGAGMMDCKKALTEAGGDLAKAEEVLRKKGLSAAAKKTGRAATEGAVASYIHMGGKIGVLVEVNC
ETDFVARTEGFQGLVKEIAMQVAAASPRWVRREEVPADVVAKELEIAKAQAREQKKPEAILEKIATGKVEKFYSEFCLME
QAWVKDDKKKIQDVLTDAVAKIGENIQIRRFARFVLGEGLEKKQENLAEEVAKAAGLQK
>Mature_218_residues
AEISAKMVQELREKTGAGMMDCKKALTEAGGDLAKAEEVLRKKGLSAAAKKTGRAATEGAVASYIHMGGKIGVLVEVNCE
TDFVARTEGFQGLVKEIAMQVAAASPRWVRREEVPADVVAKELEIAKAQAREQKKPEAILEKIATGKVEKFYSEFCLMEQ
AWVKDDKKKIQDVLTDAVAKIGENIQIRRFARFVLGEGLEKKQENLAEEVAKAAGLQK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084500, Length=204, Percent_Identity=33.8235294117647, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI291084498, Length=100, Percent_Identity=47, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI291084502, Length=100, Percent_Identity=47, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI171846268, Length=100, Percent_Identity=47, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786366, Length=98, Percent_Identity=55.1020408163265, Blast_Score=108, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19921466, Length=92, Percent_Identity=41.304347826087, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_ANAD2 (B8J9V0)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002490719.1
- ProteinModelPortal:   B8J9V0
- SMR:   B8J9V0
- GeneID:   7298996
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_0294
- HOGENOM:   HBG713289
- ProtClustDB:   PRK12332
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 23922; Mature: 23791

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEISAKMVQELREKTGAGMMDCKKALTEAGGDLAKAEEVLRKKGLSAAAKKTGRAATEG
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHH
AVASYIHMGGKIGVLVEVNCETDFVARTEGFQGLVKEIAMQVAAASPRWVRREEVPADVV
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHH
AKELEIAKAQAREQKKPEAILEKIATGKVEKFYSEFCLMEQAWVKDDKKKIQDVLTDAVA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIGENIQIRRFARFVLGEGLEKKQENLAEEVAKAAGLQK
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEISAKMVQELREKTGAGMMDCKKALTEAGGDLAKAEEVLRKKGLSAAAKKTGRAATEG
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHH
AVASYIHMGGKIGVLVEVNCETDFVARTEGFQGLVKEIAMQVAAASPRWVRREEVPADVV
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHH
AKELEIAKAQAREQKKPEAILEKIATGKVEKFYSEFCLMEQAWVKDDKKKIQDVLTDAVA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIGENIQIRRFARFVLGEGLEKKQENLAEEVAKAAGLQK
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA