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The map label for this gene is cpg2 [H]

Identifier: 220915311

GI number: 220915311

Start: 211354

End: 212502

Strand: Reverse

Name: cpg2 [H]

Synonym: A2cp1_0190

Alternate gene names: 220915311

Gene position: 212502-211354 (Counterclockwise)

Preceding gene: 220915314

Following gene: 220915306

Centisome position: 4.23

GC content: 76.59

Gene sequence:

>1149_bases
ATGGCCGCTCGCATCGAGGACGCGCTCACCTGGCTGCAGGGACAGCGCGGCGCCATGGAGGCGCTGCTGGAGCGCCTGGT
GGCGCAGAACTCCTTCACGCAGAACCGCGCCGGGGTCGAGGCGGTCGCGAACGTGGTGGCGGGGCAGCTCCGCACGCTCG
CCATGGACGTGGAGCTGCGCCCCTCGCACCACTACGGACCGCACGTCCTGTTCACCGGCCGCGCCGCGGGCGCGCCGGTG
TTCCTCCTCGGCCACACCGACACGGTGTTCCCGCCGGGCACGTTCGAGGGCTTCCGCCGCGACGGCGACCGGGCGCGGGG
GCCGGGCGCCTTCGACATGAAGGGCGGCATCGTGGCGATGCTGTTCGGGCTGGCCGCGGCGAAGCGCGCCGGGCTGCTGG
AGCGGGTCGCGGTGCGGGGCGTGCTCGTCTCCGAGGAGGAGGTGGGCTCCCCCGAGTCGCAGGCGGTGATCCGCGCCCAC
GCGGCGGGCGCCGCCTGCGCGCTCGGCTTCGAGTCCGGGCGCCCGGGCGACCTGGTGGTCACCCGCCGCAAGGGCGTGGC
GTCGGTGCGGGTCGAGGCGCGCGGGGTCGCGGCGCACTCCGGGAACGAGCACGAGAAGGGCCGGAGCGCGATCTGGTCGC
TGGCGCGGTTCGTCGATCGCGCCCAGGCGCTCACCGACTACGCGCGCGGGCTGACCGTGAACGTGGGGACCATCGCCGGC
GGCACCACCAAGAACACCGTGCCGGCCTCGGCCTCGTGCGAGGTGGACCTGCGCTTCGAGACGGTGGCGGACGGGCAGGC
GCTGCGCGAGGCGGTGGAGGCGGCCGCGCGGGAGGCCGCCATCCCCGGGACGGAGCTCGAGGTGACCGCGGGCGCCTGGC
GCGATCCGCTGGAGCGCACCCCGGCCTCGTCGGCGCTCGCGAAGGAGTACGGCGACTGCCAGCGCGAGTGCGGCCTGGGC
CAGGGCGAGGCCCCGCTCGCCGGGGGCGGCTCCGACGCCTGCACCACCGGCGCGCTCGGCATCCCCACCATCGATGCGCT
CGGCCCCCGCGGCAAGGCGTTCCACACGCCCGGCGAGGAGGTGGACCTCGGCTCGCTGGTGCCGAAGGCGAGCGCGCTGG
CGCGCTTCCTGGCGCGGCGCGCGGGCTGA

Upstream 100 bases:

>100_bases
CGGGAGCGCCCTCGCCCGGCCAGCGCCGACGCGCCGCCCGCGCGGGCTTTGCCCCGCGCGCCCGCCGCTGGCGGGCGTCG
CCGGGCCGGGGACGACACGG

Downstream 100 bases:

>100_bases
CCGCCGCCGTCGCCCGCGGGGACCTCGCGCGAGCCCGCGAACGCGGCGGCGCGAGATCACGGTCCCGCGCAGCCGGCGGA
CGGGTCCGCCGCCCCTCAGG

Product: peptidase dimerisation domain-containing protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAARIEDALTWLQGQRGAMEALLERLVAQNSFTQNRAGVEAVANVVAGQLRTLAMDVELRPSHHYGPHVLFTGRAAGAPV
FLLGHTDTVFPPGTFEGFRRDGDRARGPGAFDMKGGIVAMLFGLAAAKRAGLLERVAVRGVLVSEEEVGSPESQAVIRAH
AAGAACALGFESGRPGDLVVTRRKGVASVRVEARGVAAHSGNEHEKGRSAIWSLARFVDRAQALTDYARGLTVNVGTIAG
GTTKNTVPASASCEVDLRFETVADGQALREAVEAAAREAAIPGTELEVTAGAWRDPLERTPASSALAKEYGDCQRECGLG
QGEAPLAGGGSDACTTGALGIPTIDALGPRGKAFHTPGEEVDLGSLVPKASALARFLARRAG

Sequences:

>Translated_382_residues
MAARIEDALTWLQGQRGAMEALLERLVAQNSFTQNRAGVEAVANVVAGQLRTLAMDVELRPSHHYGPHVLFTGRAAGAPV
FLLGHTDTVFPPGTFEGFRRDGDRARGPGAFDMKGGIVAMLFGLAAAKRAGLLERVAVRGVLVSEEEVGSPESQAVIRAH
AAGAACALGFESGRPGDLVVTRRKGVASVRVEARGVAAHSGNEHEKGRSAIWSLARFVDRAQALTDYARGLTVNVGTIAG
GTTKNTVPASASCEVDLRFETVADGQALREAVEAAAREAAIPGTELEVTAGAWRDPLERTPASSALAKEYGDCQRECGLG
QGEAPLAGGGSDACTTGALGIPTIDALGPRGKAFHTPGEEVDLGSLVPKASALARFLARRAG
>Mature_381_residues
AARIEDALTWLQGQRGAMEALLERLVAQNSFTQNRAGVEAVANVVAGQLRTLAMDVELRPSHHYGPHVLFTGRAAGAPVF
LLGHTDTVFPPGTFEGFRRDGDRARGPGAFDMKGGIVAMLFGLAAAKRAGLLERVAVRGVLVSEEEVGSPESQAVIRAHA
AGAACALGFESGRPGDLVVTRRKGVASVRVEARGVAAHSGNEHEKGRSAIWSLARFVDRAQALTDYARGLTVNVGTIAGG
TTKNTVPASASCEVDLRFETVADGQALREAVEAAAREAAIPGTELEVTAGAWRDPLERTPASSALAKEYGDCQRECGLGQ
GEAPLAGGGSDACTTGALGIPTIDALGPRGKAFHTPGEEVDLGSLVPKASALARFLARRAG

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 39646; Mature: 39515

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARIEDALTWLQGQRGAMEALLERLVAQNSFTQNRAGVEAVANVVAGQLRTLAMDVELR
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEC
PSHHYGPHVLFTGRAAGAPVFLLGHTDTVFPPGTFEGFRRDGDRARGPGAFDMKGGIVAM
CCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHH
LFGLAAAKRAGLLERVAVRGVLVSEEEVGSPESQAVIRAHAAGAACALGFESGRPGDLVV
HHHHHHHHHHHHHHHHHHHHEEECHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEE
TRRKGVASVRVEARGVAAHSGNEHEKGRSAIWSLARFVDRAQALTDYARGLTVNVGTIAG
ECCCCCEEEEEEECEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GTTKNTVPASASCEVDLRFETVADGQALREAVEAAAREAAIPGTELEVTAGAWRDPLERT
CCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHC
PASSALAKEYGDCQRECGLGQGEAPLAGGGSDACTTGALGIPTIDALGPRGKAFHTPGEE
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
VDLGSLVPKASALARFLARRAG
CCHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AARIEDALTWLQGQRGAMEALLERLVAQNSFTQNRAGVEAVANVVAGQLRTLAMDVELR
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEC
PSHHYGPHVLFTGRAAGAPVFLLGHTDTVFPPGTFEGFRRDGDRARGPGAFDMKGGIVAM
CCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHH
LFGLAAAKRAGLLERVAVRGVLVSEEEVGSPESQAVIRAHAAGAACALGFESGRPGDLVV
HHHHHHHHHHHHHHHHHHHHEEECHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEE
TRRKGVASVRVEARGVAAHSGNEHEKGRSAIWSLARFVDRAQALTDYARGLTVNVGTIAG
ECCCCCEEEEEEECEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GTTKNTVPASASCEVDLRFETVADGQALREAVEAAAREAAIPGTELEVTAGAWRDPLERT
CCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHC
PASSALAKEYGDCQRECGLGQGEAPLAGGGSDACTTGALGIPTIDALGPRGKAFHTPGEE
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
VDLGSLVPKASALARFLARRAG
CCHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]