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The map label for this gene is mocR [H]

Identifier: 220915181

GI number: 220915181

Start: 66773

End: 68236

Strand: Reverse

Name: mocR [H]

Synonym: A2cp1_0059

Alternate gene names: 220915181

Gene position: 68236-66773 (Counterclockwise)

Preceding gene: 220915183

Following gene: 220915178

Centisome position: 1.36

GC content: 81.15

Gene sequence:

>1464_bases
GTGCGCACCTGGCAGACCCCGCTCGCGATCGACCGCGCCGACCCGGCCCCGCTCTCGGTGCAGATCGCCCGCGCGCTCGG
CGCGCGCATCCGCGCCGGCGCGCTCCGCCCCGGCGCGCCGCTCCCCTCCAGCCGCGCGCTGGCGCGGACGCTGGGCGTCC
ACCGCAACACCGTGCTCGCCGCCTACGGGGAGCTGGCCGCCGAGGGCTGGATCGCGTCCGACCCGGCCCGCGCCACCTTC
GTCTCGCGCGAGCTCCCGCCCCCGCCGCCGGGCGCGCCGGGCCGCGCCGGGCCCGAGGCAGGGGCGCCGGCCGCGCGCGC
CGGCTTCGACCTCCCGCCCGCCCCGGCCGACGCCACCTGGAGCACGCTGCCGCCGGGCACGCTCGAGCTCCTCGGCGGCA
CGCCCGACCCGCGGCTCGTGCCGGTGGCCGCGCTCGGGAGCGCCTACCGCCGCGCGCTGCGCCGGCGCGAGCACCTGTCC
TACGGCGACGCCGCCGGGCACCCGCGGCTGCGGGCCGCGCTCGCGCGCATGCTGGGCGAGGCGCGCGGGCTGGCGGTGGC
AGCGGACGGGATCCTCGTCACCCGCGGCGCCCAGATGGCGCTCTCGCTCGCCGGGCGTGCGCTGCTCAGGTCGGGCGACG
GCGTCGCGGTCGAGGCGCTCGGGTACCGGCCGGCGTGGGAGTCGCTGCGCCTGGCGGGGCTCCGCACCGTCCCGGTGCCG
GTGGACGCGCGCGGGCTGCAGGTGGAGCGCCTCGAGGCGCTCGCCGCGGCCGGCGCCGTCCGCGCCGTCTACCTCACCCC
GCACCACCAGTACCCGACCACCGTCACGCTCGCCCCCGCCCGGCGGCTGGCGCTGCTCGAGGTGGCCCGTCGCGCGCGGC
TGCTCGTGCTCGAGGACGACTACGACGCCGAGTTCCACTACGACGGCCGCCCGGTGCCGCCGCTCGCCAGCGCCGACGGC
GCGGGGGTGGTGGTGTACGTGGGCACGCTCTCGAAGGTGCTCGCCCCTGGGCTGCGCATCGGCTGGCTGGCCGGCCCGCC
GGACGCGATCGAGCGGGTCACCGCGCACCGCCGCTTCCTCGACCGGCAGGGCGACCTCGCGGTGGAGGCGGCCGTCGCCG
AGCTGTTCGAGGAGGGCGAGGCGCAGCGGCACGCCTGGCGGACCCGCCGCGTCTACGCGGGGCGGCGCGAGGCGCTCGCG
GCCGCGCTGCGCGCGCGGCTCCCCGGCGCGCTCTCCTTCCGGATGCCGGCGGGCGGGATGGCGCTCTGGTGCCGGGTCGC
GCCCGGCCTCGACCCGGAGGCGTGGGCGGCGCGCGCCCTCCGCGCCGGGGTGGCGGTGCAGCCGGGCCGCCTGTTCGCGC
ACGACCGCCGGGCCCGTCCGTTCCTCCGGCTCGGCTTCGGCCGCCTCGACGAGCGCGAGCTGGCCGAGGCGGTGCGCCGG
CTGGCCGCGGCGCTGCCGCGGTGA

Upstream 100 bases:

>100_bases
TCCCCGCGGCCGGCCCGGAAGATCTCGCGTCGCATGCGCGGCAGGCTGCGCCGGGGCTGGTCTGGCGAGAAGGTCCAGTT
TCGAGGTATCGGATGGACCA

Downstream 100 bases:

>100_bases
GGTCGGAGGGCGAAGCGAGCGGCGCGTCGCCGCGCGCCGGCGGTCAGCGCGCCGGAGCGAGCGGCGCGTAGCGCCGGGCC
GGCTCCTCGCCGGCGAGGAC

Product: GntR family transcriptional regulator with aminotransferase domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MRTWQTPLAIDRADPAPLSVQIARALGARIRAGALRPGAPLPSSRALARTLGVHRNTVLAAYGELAAEGWIASDPARATF
VSRELPPPPPGAPGRAGPEAGAPAARAGFDLPPAPADATWSTLPPGTLELLGGTPDPRLVPVAALGSAYRRALRRREHLS
YGDAAGHPRLRAALARMLGEARGLAVAADGILVTRGAQMALSLAGRALLRSGDGVAVEALGYRPAWESLRLAGLRTVPVP
VDARGLQVERLEALAAAGAVRAVYLTPHHQYPTTVTLAPARRLALLEVARRARLLVLEDDYDAEFHYDGRPVPPLASADG
AGVVVYVGTLSKVLAPGLRIGWLAGPPDAIERVTAHRRFLDRQGDLAVEAAVAELFEEGEAQRHAWRTRRVYAGRREALA
AALRARLPGALSFRMPAGGMALWCRVAPGLDPEAWAARALRAGVAVQPGRLFAHDRRARPFLRLGFGRLDERELAEAVRR
LAAALPR

Sequences:

>Translated_487_residues
MRTWQTPLAIDRADPAPLSVQIARALGARIRAGALRPGAPLPSSRALARTLGVHRNTVLAAYGELAAEGWIASDPARATF
VSRELPPPPPGAPGRAGPEAGAPAARAGFDLPPAPADATWSTLPPGTLELLGGTPDPRLVPVAALGSAYRRALRRREHLS
YGDAAGHPRLRAALARMLGEARGLAVAADGILVTRGAQMALSLAGRALLRSGDGVAVEALGYRPAWESLRLAGLRTVPVP
VDARGLQVERLEALAAAGAVRAVYLTPHHQYPTTVTLAPARRLALLEVARRARLLVLEDDYDAEFHYDGRPVPPLASADG
AGVVVYVGTLSKVLAPGLRIGWLAGPPDAIERVTAHRRFLDRQGDLAVEAAVAELFEEGEAQRHAWRTRRVYAGRREALA
AALRARLPGALSFRMPAGGMALWCRVAPGLDPEAWAARALRAGVAVQPGRLFAHDRRARPFLRLGFGRLDERELAEAVRR
LAAALPR
>Mature_487_residues
MRTWQTPLAIDRADPAPLSVQIARALGARIRAGALRPGAPLPSSRALARTLGVHRNTVLAAYGELAAEGWIASDPARATF
VSRELPPPPPGAPGRAGPEAGAPAARAGFDLPPAPADATWSTLPPGTLELLGGTPDPRLVPVAALGSAYRRALRRREHLS
YGDAAGHPRLRAALARMLGEARGLAVAADGILVTRGAQMALSLAGRALLRSGDGVAVEALGYRPAWESLRLAGLRTVPVP
VDARGLQVERLEALAAAGAVRAVYLTPHHQYPTTVTLAPARRLALLEVARRARLLVLEDDYDAEFHYDGRPVPPLASADG
AGVVVYVGTLSKVLAPGLRIGWLAGPPDAIERVTAHRRFLDRQGDLAVEAAVAELFEEGEAQRHAWRTRRVYAGRREALA
AALRARLPGALSFRMPAGGMALWCRVAPGLDPEAWAARALRAGVAVQPGRLFAHDRRARPFLRLGFGRLDERELAEAVRR
LAAALPR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=392, Percent_Identity=26.0204081632653, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI33469970, Length=392, Percent_Identity=26.0204081632653, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1790797, Length=485, Percent_Identity=28.0412371134021, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=26.7094017094017, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI21356535, Length=400, Percent_Identity=25.25, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51746; Mature: 51746

Theoretical pI: Translated: 11.61; Mature: 11.61

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTWQTPLAIDRADPAPLSVQIARALGARIRAGALRPGAPLPSSRALARTLGVHRNTVLA
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHH
AYGELAAEGWIASDPARATFVSRELPPPPPGAPGRAGPEAGAPAARAGFDLPPAPADATW
HHHHHHHCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
STLPPGTLELLGGTPDPRLVPVAALGSAYRRALRRREHLSYGDAAGHPRLRAALARMLGE
CCCCCCHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ARGLAVAADGILVTRGAQMALSLAGRALLRSGDGVAVEALGYRPAWESLRLAGLRTVPVP
HCCCEEEECCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCEECCCC
VDARGLQVERLEALAAAGAVRAVYLTPHHQYPTTVTLAPARRLALLEVARRARLLVLEDD
CCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHCEEEEEECC
YDAEFHYDGRPVPPLASADGAGVVVYVGTLSKVLAPGLRIGWLAGPPDAIERVTAHRRFL
CCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
DRQGDLAVEAAVAELFEEGEAQRHAWRTRRVYAGRREALAAALRARLPGALSFRMPAGGM
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCE
ALWCRVAPGLDPEAWAARALRAGVAVQPGRLFAHDRRARPFLRLGFGRLDERELAEAVRR
EEEEEECCCCCHHHHHHHHHHCCCEECCCHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHH
LAAALPR
HHHHCCC
>Mature Secondary Structure
MRTWQTPLAIDRADPAPLSVQIARALGARIRAGALRPGAPLPSSRALARTLGVHRNTVLA
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHH
AYGELAAEGWIASDPARATFVSRELPPPPPGAPGRAGPEAGAPAARAGFDLPPAPADATW
HHHHHHHCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
STLPPGTLELLGGTPDPRLVPVAALGSAYRRALRRREHLSYGDAAGHPRLRAALARMLGE
CCCCCCHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ARGLAVAADGILVTRGAQMALSLAGRALLRSGDGVAVEALGYRPAWESLRLAGLRTVPVP
HCCCEEEECCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCEECCCC
VDARGLQVERLEALAAAGAVRAVYLTPHHQYPTTVTLAPARRLALLEVARRARLLVLEDD
CCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHCEEEEEECC
YDAEFHYDGRPVPPLASADGAGVVVYVGTLSKVLAPGLRIGWLAGPPDAIERVTAHRRFL
CCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
DRQGDLAVEAAVAELFEEGEAQRHAWRTRRVYAGRREALAAALRARLPGALSFRMPAGGM
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCE
ALWCRVAPGLDPEAWAARALRAGVAVQPGRLFAHDRRARPFLRLGFGRLDERELAEAVRR
EEEEEECCCCCHHHHHHHHHHCCCEECCCHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHH
LAAALPR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]