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The map label for this gene is paaK [H]

Identifier: 220915174

GI number: 220915174

Start: 59300

End: 60625

Strand: Reverse

Name: paaK [H]

Synonym: A2cp1_0052

Alternate gene names: 220915174

Gene position: 60625-59300 (Counterclockwise)

Preceding gene: 220915175

Following gene: 220915170

Centisome position: 1.21

GC content: 73.98

Gene sequence:

>1326_bases
ATGGCCCGCTTCGCGCTCGAGAACCGGATCCTCGATCCGGAGGAGACGCTCGACCGTGACGCGCTCGCCGCGCTCCAGGG
CCGCCGCCTCGCCGAGACCGTCCGCCGCGCCCGCGCGGTGCCGCACCACCGCAAGGCGCTGGAGCGGGCCGGCGTCCGCG
ACGAGGACCTGCGCGGCCCGGCCGACGTGCGGCGCCTGCCGTTCACGGTGAAGGACGACCTCCGGCAGAGCTACCCGCTC
GGCCTGCTGGCGGTGCCGCGCGAGCAGGTGGTGCGCATCCACGGCTCCTCCGGCACCACCGGCCGCCCCACCTTCGTCGC
GTACACCCGCCGCGACCTCGACACCTGGACCGGCCTGGTGGCCCGCTTCCTGGTGGCCGGCGGGCTCCGCCCCGAGCACA
CCGTCCACGTCGCCTTCGGCTACGGCCTGTTCACCGGCGGCTTCGGGCTGCACTACGGCATCGAGCGGGTGGGCGCCGCG
GTGGTCCCGTCCGGCGGCGGGAACACGCCGCGGCAGGTGCGGCTCATCTGCGATCTCTCCGCCGACGTGCTCATCAGCAC
GCCGTCCTACGCGCTGCACGTGGGCGAGGTGGCGCGCGCCGAGGGGCTGAAGCCCGGCGACCTGCCGCTCCGGTACGGCC
ACTTCGGCGGCGAGCCCTGGACCGAGGAGATGCGCGGGGAGATCGAGCGGTCGCTCGGGATCCTCGCCTTCAACAACTAC
GGGCTCTCCGAGGTGATCGGGCCGGGCGTGGCCGGCGAGTGCCCGGCGCGCGATGGCATGCACGTGCAGGAGGACCACTT
CATCGTCGAGTGCCTCGACCCGGTCACGCTCGAGCCGGTGCCGGACGGCGAGGTGGGCGAGCTCGTCTTCACCTCGCTCA
CGAAGGAGGCGATGCCGGTGCTGCGCTACCGCACCCGCGACCTCGCCGCGCTCGACCGCTCCCCCTGCCCCTGCGGCCGC
ACCGGCGTGCGCATGAGCCGGGTGCGCGGCCGCTCCGACGACATGCTCATCATCCGCGGCGTGAACGTGTTCCCGTCGCA
GGTGGAGGAGGCGCTGCTCCGCGTCGAGGGCACCGCCCCGCACTACCTCATCGAGGTCTCGCGCCCCGGCGCGCTCGACG
AGGCGGTGGTGAAGGTGGAGGTCCGGCCCGAGGACTTCCGCGACGAGATGCGCGAGATGGTGGGCCTGCGCGACCGCATC
GATCGCGAGATCCACGCGGTGACCGGGATCCGGATGATCGTGGAGCTGGTGGCGCCGAACACGCTGGAGCGCTCCGCCGG
CAAGGCGCGGCGGGTGCTCGATCACCGGAAGGCCGGGCCGGCGTAG

Upstream 100 bases:

>100_bases
CCGGCTCTCGGATCCGGACCGTGCCGCCGCGCTGCTGCAGGCGCGCGGCGTCCGCCTGGTGGGCGCGGCCGAGCTGTTCG
CGCGCGCGGGGGCCTAGCCG

Downstream 100 bases:

>100_bases
CCCTTCGGCTCCGGCGCTCGTCCCGACCCTTCGACTCCGGCGGGCCCTTGGCCCGCCTACGCTCAGGGTGAGCGATCGAG
GCCGCTCATCCCGAGCGTAG

Product: Phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MARFALENRILDPEETLDRDALAALQGRRLAETVRRARAVPHHRKALERAGVRDEDLRGPADVRRLPFTVKDDLRQSYPL
GLLAVPREQVVRIHGSSGTTGRPTFVAYTRRDLDTWTGLVARFLVAGGLRPEHTVHVAFGYGLFTGGFGLHYGIERVGAA
VVPSGGGNTPRQVRLICDLSADVLISTPSYALHVGEVARAEGLKPGDLPLRYGHFGGEPWTEEMRGEIERSLGILAFNNY
GLSEVIGPGVAGECPARDGMHVQEDHFIVECLDPVTLEPVPDGEVGELVFTSLTKEAMPVLRYRTRDLAALDRSPCPCGR
TGVRMSRVRGRSDDMLIIRGVNVFPSQVEEALLRVEGTAPHYLIEVSRPGALDEAVVKVEVRPEDFRDEMREMVGLRDRI
DREIHAVTGIRMIVELVAPNTLERSAGKARRVLDHRKAGPA

Sequences:

>Translated_441_residues
MARFALENRILDPEETLDRDALAALQGRRLAETVRRARAVPHHRKALERAGVRDEDLRGPADVRRLPFTVKDDLRQSYPL
GLLAVPREQVVRIHGSSGTTGRPTFVAYTRRDLDTWTGLVARFLVAGGLRPEHTVHVAFGYGLFTGGFGLHYGIERVGAA
VVPSGGGNTPRQVRLICDLSADVLISTPSYALHVGEVARAEGLKPGDLPLRYGHFGGEPWTEEMRGEIERSLGILAFNNY
GLSEVIGPGVAGECPARDGMHVQEDHFIVECLDPVTLEPVPDGEVGELVFTSLTKEAMPVLRYRTRDLAALDRSPCPCGR
TGVRMSRVRGRSDDMLIIRGVNVFPSQVEEALLRVEGTAPHYLIEVSRPGALDEAVVKVEVRPEDFRDEMREMVGLRDRI
DREIHAVTGIRMIVELVAPNTLERSAGKARRVLDHRKAGPA
>Mature_440_residues
ARFALENRILDPEETLDRDALAALQGRRLAETVRRARAVPHHRKALERAGVRDEDLRGPADVRRLPFTVKDDLRQSYPLG
LLAVPREQVVRIHGSSGTTGRPTFVAYTRRDLDTWTGLVARFLVAGGLRPEHTVHVAFGYGLFTGGFGLHYGIERVGAAV
VPSGGGNTPRQVRLICDLSADVLISTPSYALHVGEVARAEGLKPGDLPLRYGHFGGEPWTEEMRGEIERSLGILAFNNYG
LSEVIGPGVAGECPARDGMHVQEDHFIVECLDPVTLEPVPDGEVGELVFTSLTKEAMPVLRYRTRDLAALDRSPCPCGRT
GVRMSRVRGRSDDMLIIRGVNVFPSQVEEALLRVEGTAPHYLIEVSRPGALDEAVVKVEVRPEDFRDEMREMVGLRDRID
REIHAVTGIRMIVELVAPNTLERSAGKARRVLDHRKAGPA

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=436, Percent_Identity=50.2293577981651, Blast_Score=403, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48605; Mature: 48474

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFALENRILDPEETLDRDALAALQGRRLAETVRRARAVPHHRKALERAGVRDEDLRGP
CCCCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
ADVRRLPFTVKDDLRQSYPLGLLAVPREQVVRIHGSSGTTGRPTFVAYTRRDLDTWTGLV
HHHHHCCCCHHHHHHHHCCCCEEECCHHHEEEEECCCCCCCCCEEEEEECCCHHHHHHHH
ARFLVAGGLRPEHTVHVAFGYGLFTGGFGLHYGIERVGAAVVPSGGGNTPRQVRLICDLS
HHHHHHCCCCCCCEEEEEEECHHHHCCCHHHHHHHHHCCEEECCCCCCCCCEEEEEEECC
ADVLISTPSYALHVGEVARAEGLKPGDLPLRYGHFGGEPWTEEMRGEIERSLGILAFNNY
CCEEEECCCCEEEHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCC
GLSEVIGPGVAGECPARDGMHVQEDHFIVECLDPVTLEPVPDGEVGELVFTSLTKEAMPV
CHHHHHCCCCCCCCCCCCCCEECCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHH
LRYRTRDLAALDRSPCPCGRTGVRMSRVRGRSDDMLIIRGVNVFPSQVEEALLRVEGTAP
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCC
HYLIEVSRPGALDEAVVKVEVRPEDFRDEMREMVGLRDRIDREIHAVTGIRMIVELVAPN
EEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TLERSAGKARRVLDHRKAGPA
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARFALENRILDPEETLDRDALAALQGRRLAETVRRARAVPHHRKALERAGVRDEDLRGP
CCCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
ADVRRLPFTVKDDLRQSYPLGLLAVPREQVVRIHGSSGTTGRPTFVAYTRRDLDTWTGLV
HHHHHCCCCHHHHHHHHCCCCEEECCHHHEEEEECCCCCCCCCEEEEEECCCHHHHHHHH
ARFLVAGGLRPEHTVHVAFGYGLFTGGFGLHYGIERVGAAVVPSGGGNTPRQVRLICDLS
HHHHHHCCCCCCCEEEEEEECHHHHCCCHHHHHHHHHCCEEECCCCCCCCCEEEEEEECC
ADVLISTPSYALHVGEVARAEGLKPGDLPLRYGHFGGEPWTEEMRGEIERSLGILAFNNY
CCEEEECCCCEEEHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCC
GLSEVIGPGVAGECPARDGMHVQEDHFIVECLDPVTLEPVPDGEVGELVFTSLTKEAMPV
CHHHHHCCCCCCCCCCCCCCEECCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHH
LRYRTRDLAALDRSPCPCGRTGVRMSRVRGRSDDMLIIRGVNVFPSQVEEALLRVEGTAP
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCC
HYLIEVSRPGALDEAVVKVEVRPEDFRDEMREMVGLRDRIDREIHAVTGIRMIVELVAPN
EEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TLERSAGKARRVLDHRKAGPA
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]