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The map label for this gene is kup [H]

Identifier: 220905486

GI number: 220905486

Start: 2680874

End: 2682688

Strand: Reverse

Name: kup [H]

Synonym: Ddes_2224

Alternate gene names: 220905486

Gene position: 2682688-2680874 (Counterclockwise)

Preceding gene: 220905487

Following gene: 220905484

Centisome position: 93.36

GC content: 54.44

Gene sequence:

>1815_bases
ATGGACACGCAAAAAATATCTCCTGCCAGTGTGATAAAATCTCTGGGGCTTGTATTTGGTGATATCGGCACAAGCCCCAT
CTACACCCTGGCAGTCATTTTTATGATGACAGAAAGAACCGAGGCAAACTTTATAGGTATTCTTTCGCTCATCATATGGA
CACTGCTTTTGCTTGTTACTGTAGAGTATGCCTGGCTGGCAATGAGCCTGAGCAAGGCCGGAGAGGGCGGCACAATTGTG
CTGCTCTCCATCCTGCGGCCCATGTTGCAGTCCGGAAAGAAAATAGGTGTGGCTTCGGTGCTGGCTTTTATAGGGGTTTC
ACTGCTTGTGGGGGATGGCGTCATTACTCCGGCCATCACCATACTTTCGGCAGTGGAAGGGCTGGTGCTGCTGCCCGGCC
TTGAGGACGTCTCGCAAGGTACGCTTGTTGTACTGGCCCTGCTTGTGGCCGTGTTTCTTTTTTCCATCCAGAAGAACGGC
AGCAGCAGGCTTTCCGCTTTTTTTGGCCCTGTCATGGCCGTGTGGTTCGGTGTGCTGGCCTGTTCCGGCCTGGCGGCGCT
CAGCCAGTTTCCGGCGGTGCTGAAGGCCGTTAACCCCTGGTATGGCATCGACTTCATGCTGCGCAACGGTCTGGCGGGAT
TTTTTGTGCTGTCCGAGGTCATCCTGTGCGCCACGGGCGGCGAGGCCCTGTACGCCGATATGGGGCATATGGGGCGCAAG
CCCATCCTGGCGGCCTGGGGCATGGTCTTTACCGCACTTTTGCTGTGCTATATGGGGCAGACGGCCTTTCTCGTCCATAA
TCCGGGCGCGAACAACGTGCTTTTTGAAATGGTTCACAGCCAGGCCCGCTGGCTCTACGCCCCCTTTCTGGTGCTGAGCC
TGCTGGCGACCATCATTGCGTCCCAGTCGCTCATAAGCGGCATATTTTCCATCATGTACCAGAGCATGGCCACGCATATC
ATGCCTCTTTTCAAGGTGGATTACACCTCAAGGGAGATGCACTCGCAGATCTACATAGGCTCTGTAAACTGGGCCCTGTT
TCTTGCCGTGGTGCTGGTCATTATGGGCTTCAAGGAGTCGCACAGGCTCGCCGCGGCCTACGGCCTGGCCGTTACCGGAA
CCATGACCATTACGGGCATGCTTATGGTCTGGATATTTCACCTGAAAAACCGCCCCTGGCTGTGCGCCACGGCTGCCGGC
ATCTGCGCGCTGGACGTGGTGTATCTGGTGGCAAACTTTTACAAGCTGCCGCACGGGGGCTACTGGTCGCTGGTCATTGC
CATGATACCCTTGGGGATCATCCTCATTTACACGCAGGGGCAGAAGGCCGTGTACCAGCGCATGCAGCCCATGCCCCGGG
ATGTCTTTATGGAAAGGTTTACAAAGCTGAGAAGGCAGGGCCACATCATCAAGGGGACGGCCATCTTTTTTCTGCGTAGC
CTGGACAGCATTTCGCCGTATATCTGCAAGACCATGTTTGATAACGGCATTATTTACGAGCGCAACGTGATGCTCAGCAT
TTCACGCACATATGAGCCGCAGGGGCTGGAATGCCGCTTTGAAGATACGCATGTTGCCGGTATCCAGGTATTTACGGTCA
CCGCAGGATATATGGAACATATTGATATTGACGGACTGCTGGAAAAAACGGGCATAAAGCCGCGTGCTATCTTCTATGGT
GTCGAGGACATATTCACCCGTTCCATTGTCTGGAAAGTCTACGCGGTCATCAAAAAGCTGGCTCCGCCCTTTGTGCAGTT
TTATAAGCTGCCGCTGCATTCCGTACACGGGGTTATCAGCCGTATTTCACTTTAG

Upstream 100 bases:

>100_bases
TTCCGGCATGCCAGCCGTGCATGTATAACTGTTTTCTGCTTTCTGCCGTCCGTAGGCATGCGTGGGCGGCCCTGCCTGAA
CCGGCTTCCGATGGAGGCAT

Downstream 100 bases:

>100_bases
GGCGTTTTGGGGCACCCTTTGAAGGGCGGCATCCGATATCCGTTATCCGTGCAGCCCGGGGCTGCCTGCAAAAGGCCGGG
AAATCCCGGCCTTTTGGTGT

Product: K potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MDTQKISPASVIKSLGLVFGDIGTSPIYTLAVIFMMTERTEANFIGILSLIIWTLLLLVTVEYAWLAMSLSKAGEGGTIV
LLSILRPMLQSGKKIGVASVLAFIGVSLLVGDGVITPAITILSAVEGLVLLPGLEDVSQGTLVVLALLVAVFLFSIQKNG
SSRLSAFFGPVMAVWFGVLACSGLAALSQFPAVLKAVNPWYGIDFMLRNGLAGFFVLSEVILCATGGEALYADMGHMGRK
PILAAWGMVFTALLLCYMGQTAFLVHNPGANNVLFEMVHSQARWLYAPFLVLSLLATIIASQSLISGIFSIMYQSMATHI
MPLFKVDYTSREMHSQIYIGSVNWALFLAVVLVIMGFKESHRLAAAYGLAVTGTMTITGMLMVWIFHLKNRPWLCATAAG
ICALDVVYLVANFYKLPHGGYWSLVIAMIPLGIILIYTQGQKAVYQRMQPMPRDVFMERFTKLRRQGHIIKGTAIFFLRS
LDSISPYICKTMFDNGIIYERNVMLSISRTYEPQGLECRFEDTHVAGIQVFTVTAGYMEHIDIDGLLEKTGIKPRAIFYG
VEDIFTRSIVWKVYAVIKKLAPPFVQFYKLPLHSVHGVISRISL

Sequences:

>Translated_604_residues
MDTQKISPASVIKSLGLVFGDIGTSPIYTLAVIFMMTERTEANFIGILSLIIWTLLLLVTVEYAWLAMSLSKAGEGGTIV
LLSILRPMLQSGKKIGVASVLAFIGVSLLVGDGVITPAITILSAVEGLVLLPGLEDVSQGTLVVLALLVAVFLFSIQKNG
SSRLSAFFGPVMAVWFGVLACSGLAALSQFPAVLKAVNPWYGIDFMLRNGLAGFFVLSEVILCATGGEALYADMGHMGRK
PILAAWGMVFTALLLCYMGQTAFLVHNPGANNVLFEMVHSQARWLYAPFLVLSLLATIIASQSLISGIFSIMYQSMATHI
MPLFKVDYTSREMHSQIYIGSVNWALFLAVVLVIMGFKESHRLAAAYGLAVTGTMTITGMLMVWIFHLKNRPWLCATAAG
ICALDVVYLVANFYKLPHGGYWSLVIAMIPLGIILIYTQGQKAVYQRMQPMPRDVFMERFTKLRRQGHIIKGTAIFFLRS
LDSISPYICKTMFDNGIIYERNVMLSISRTYEPQGLECRFEDTHVAGIQVFTVTAGYMEHIDIDGLLEKTGIKPRAIFYG
VEDIFTRSIVWKVYAVIKKLAPPFVQFYKLPLHSVHGVISRISL
>Mature_604_residues
MDTQKISPASVIKSLGLVFGDIGTSPIYTLAVIFMMTERTEANFIGILSLIIWTLLLLVTVEYAWLAMSLSKAGEGGTIV
LLSILRPMLQSGKKIGVASVLAFIGVSLLVGDGVITPAITILSAVEGLVLLPGLEDVSQGTLVVLALLVAVFLFSIQKNG
SSRLSAFFGPVMAVWFGVLACSGLAALSQFPAVLKAVNPWYGIDFMLRNGLAGFFVLSEVILCATGGEALYADMGHMGRK
PILAAWGMVFTALLLCYMGQTAFLVHNPGANNVLFEMVHSQARWLYAPFLVLSLLATIIASQSLISGIFSIMYQSMATHI
MPLFKVDYTSREMHSQIYIGSVNWALFLAVVLVIMGFKESHRLAAAYGLAVTGTMTITGMLMVWIFHLKNRPWLCATAAG
ICALDVVYLVANFYKLPHGGYWSLVIAMIPLGIILIYTQGQKAVYQRMQPMPRDVFMERFTKLRRQGHIIKGTAIFFLRS
LDSISPYICKTMFDNGIIYERNVMLSISRTYEPQGLECRFEDTHVAGIQVFTVTAGYMEHIDIDGLLEKTGIKPRAIFYG
VEDIFTRSIVWKVYAVIKKLAPPFVQFYKLPLHSVHGVISRISL

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=569, Percent_Identity=33.2161687170475, Blast_Score=279, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 66428; Mature: 66428

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQKISPASVIKSLGLVFGDIGTSPIYTLAVIFMMTERTEANFIGILSLIIWTLLLLVT
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VEYAWLAMSLSKAGEGGTIVLLSILRPMLQSGKKIGVASVLAFIGVSLLVGDGVITPAIT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
ILSAVEGLVLLPGLEDVSQGTLVVLALLVAVFLFSIQKNGSSRLSAFFGPVMAVWFGVLA
HHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
CSGLAALSQFPAVLKAVNPWYGIDFMLRNGLAGFFVLSEVILCATGGEALYADMGHMGRK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PILAAWGMVFTALLLCYMGQTAFLVHNPGANNVLFEMVHSQARWLYAPFLVLSLLATIIA
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQSLISGIFSIMYQSMATHIMPLFKVDYTSREMHSQIYIGSVNWALFLAVVLVIMGFKES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEECCHHHHHHHHHHHHHCCCCC
HRLAAAYGLAVTGTMTITGMLMVWIFHLKNRPWLCATAAGICALDVVYLVANFYKLPHGG
CHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
YWSLVIAMIPLGIILIYTQGQKAVYQRMQPMPRDVFMERFTKLRRQGHIIKGTAIFFLRS
HHHHHHHHHHHCEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHH
LDSISPYICKTMFDNGIIYERNVMLSISRTYEPQGLECRFEDTHVAGIQVFTVTAGYMEH
HHCCCHHHHHHHHCCCEEEECCEEEEEECCCCCCCCEEEECCCEEEEEEEEEEEHHHHHH
IDIDGLLEKTGIKPRAIFYGVEDIFTRSIVWKVYAVIKKLAPPFVQFYKLPLHSVHGVIS
CCHHHHHHHCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RISL
HCCC
>Mature Secondary Structure
MDTQKISPASVIKSLGLVFGDIGTSPIYTLAVIFMMTERTEANFIGILSLIIWTLLLLVT
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VEYAWLAMSLSKAGEGGTIVLLSILRPMLQSGKKIGVASVLAFIGVSLLVGDGVITPAIT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
ILSAVEGLVLLPGLEDVSQGTLVVLALLVAVFLFSIQKNGSSRLSAFFGPVMAVWFGVLA
HHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
CSGLAALSQFPAVLKAVNPWYGIDFMLRNGLAGFFVLSEVILCATGGEALYADMGHMGRK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PILAAWGMVFTALLLCYMGQTAFLVHNPGANNVLFEMVHSQARWLYAPFLVLSLLATIIA
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQSLISGIFSIMYQSMATHIMPLFKVDYTSREMHSQIYIGSVNWALFLAVVLVIMGFKES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEECCHHHHHHHHHHHHHCCCCC
HRLAAAYGLAVTGTMTITGMLMVWIFHLKNRPWLCATAAGICALDVVYLVANFYKLPHGG
CHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
YWSLVIAMIPLGIILIYTQGQKAVYQRMQPMPRDVFMERFTKLRRQGHIIKGTAIFFLRS
HHHHHHHHHHHCEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHH
LDSISPYICKTMFDNGIIYERNVMLSISRTYEPQGLECRFEDTHVAGIQVFTVTAGYMEH
HHCCCHHHHHHHHCCCEEEECCEEEEEECCCCCCCCEEEECCCEEEEEEEEEEEHHHHHH
IDIDGLLEKTGIKPRAIFYGVEDIFTRSIVWKVYAVIKKLAPPFVQFYKLPLHSVHGVIS
CCHHHHHHHCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RISL
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]