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The map label for this gene is rnpA

Identifier: 220905231

GI number: 220905231

Start: 2374133

End: 2374525

Strand: Reverse

Name: rnpA

Synonym: Ddes_1969

Alternate gene names: 220905231

Gene position: 2374525-2374133 (Counterclockwise)

Preceding gene: 220905232

Following gene: 220905230

Centisome position: 82.64

GC content: 61.58

Gene sequence:

>393_bases
ATGCGCCGGTACCTCCTGCCCCGACAGTTGCGCATCCGCCGCCGGGTGGAGTTTACAGCCTGTTACGAGCGGGGCAGGCG
CTACCACACCGAGCACTTCCTTGTATTCGTGTTGCCGCGGGCTTGTCCCGGTCTTCGCGCGCGTACCGGCATGGCCGTTT
CCCGCAAGGTGGGTAAGGCTGTGGTGCGCAATCGCGTCAAGAGACTCTTGCGGGAATTTTACCGCCTGCACAGAGAGGAG
CTGCCCGTGGAGGCCGATATTGTTACCGTAGCAAAAAAGCATGCTGGAGAAGCCGCACTGGATTATGCCCGTGTGGCTGC
TGAGCTTTTGCCCCTGTTGCGGCGTATGGCCCGGCATCTGCCGGGCTCTTCGGCATTGGATGGTCTGCCATGA

Upstream 100 bases:

>100_bases
GGGGCGCGCGGTGCTGCGCCGTCGTCGCGCCAAGGGCCGTAAACGCCTGAGCGCCTAGTTGAACGGGGGGACTGCCCCCG
TTCGTCATTAGGGAGCTTTC

Downstream 100 bases:

>100_bases
GCCACATGTTGCGCGTGATCTGCGTTTTTCCCATACGCGTTTACCAGCGTTGCATCTCGCCTGTGCTGCCCCCTGCCTGC
CGTTATTATCCTACCTGTTC

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MRRYLLPRQLRIRRRVEFTACYERGRRYHTEHFLVFVLPRACPGLRARTGMAVSRKVGKAVVRNRVKRLLREFYRLHREE
LPVEADIVTVAKKHAGEAALDYARVAAELLPLLRRMARHLPGSSALDGLP

Sequences:

>Translated_130_residues
MRRYLLPRQLRIRRRVEFTACYERGRRYHTEHFLVFVLPRACPGLRARTGMAVSRKVGKAVVRNRVKRLLREFYRLHREE
LPVEADIVTVAKKHAGEAALDYARVAAELLPLLRRMARHLPGSSALDGLP
>Mature_130_residues
MRRYLLPRQLRIRRRVEFTACYERGRRYHTEHFLVFVLPRACPGLRARTGMAVSRKVGKAVVRNRVKRLLREFYRLHREE
LPVEADIVTVAKKHAGEAALDYARVAAELLPLLRRMARHLPGSSALDGLP

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_DESDA (B8J2U6)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480543.1
- GeneID:   7285685
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1969
- HOGENOM:   HBG728160
- ProtClustDB:   CLSK2546364
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 15111; Mature: 15111

Theoretical pI: Translated: 11.86; Mature: 11.86

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRYLLPRQLRIRRRVEFTACYERGRRYHTEHFLVFVLPRACPGLRARTGMAVSRKVGKA
CCCCCCHHHHHHHHHHHHHHHHHHCCHHCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHH
VVRNRVKRLLREFYRLHREELPVEADIVTVAKKHAGEAALDYARVAAELLPLLRRMARHL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
PGSSALDGLP
CCCCCCCCCC
>Mature Secondary Structure
MRRYLLPRQLRIRRRVEFTACYERGRRYHTEHFLVFVLPRACPGLRARTGMAVSRKVGKA
CCCCCCHHHHHHHHHHHHHHHHHHCCHHCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHH
VVRNRVKRLLREFYRLHREELPVEADIVTVAKKHAGEAALDYARVAAELLPLLRRMARHL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
PGSSALDGLP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA