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The map label for this gene is katA [H]

Identifier: 220904762

GI number: 220904762

Start: 1784948

End: 1786405

Strand: Reverse

Name: katA [H]

Synonym: Ddes_1494

Alternate gene names: 220904762

Gene position: 1786405-1784948 (Counterclockwise)

Preceding gene: 220904763

Following gene: 220904761

Centisome position: 62.17

GC content: 55.28

Gene sequence:

>1458_bases
ATGTCGAACGACCAGAACAAACTTACCAATAATGCCGGTGCGCCAGTGGCTGACAACAACAGGGTGCTTACTGCAGGGCC
GCGTGGCCCCATGTTGTTGCAGGACGTATGGTTTCTTGAAAAGCTGGCCCATTTCGACCGTGAAGTTATCCCGGAACGGC
GCATGCACGCCAAAGGGTCGGGCGCTTACGGCACTTTTACTGTCACGCACGATATCACCCGTTTTACTAAAGCTTCCCTC
TTTTCTCAGATAGGCAAAAAAACAGATCTTTTTGTGCGCTTTTCCACAGTGGCGGGTGAACGCGGCGCGGCCGATGCCGA
GCGTGACATCCGCGGATTTGCTATCAAGTTCTATACAGATGAAGGCAATTTTGACCTTGTGGGTAATAACACTCCCGTTT
TTTTCCTGCGGGATCCTTTAAAATTTCCCGACCTCAACCATGTGGTCAAACGCAATCCGCGCACCAACATGCACAGCGCC
CAGGACAACTGGGATTTCTGGTCTCTCTTGCCCGAAGCCCTGCATCAGGTCACCGTGGTCATGAGCGATCGCGGTATTCC
GGCCTCGTATCGCCACATGCACGGCTTCGGCAGCCATACTTTCAGTTTTATCAATGCGGACAATGAGCGCTTCTGGGTCA
AGTTTCACTTTAAAACCCAGCAGGGAATCAAAAATCTTACCGATGCCGAGGCTCAGGATCTTGTGGGCCGCGACCGCGAC
AGTCATCAGCGCGATCTGTTTGAGCATATTGAAAAAGGCGACTTTCCTCGCTGGAAGCTTTTTGTGCAGGTCATGCCCGA
AACTGACGCTGAAAAACTGCCTTACCATCCCTTTGACCTCACCAAGGTCTGGTACCATAAAGACGTACCCATGTACGAAG
TGGGTGTGCTGGAACTGAACCGCAATCCTGAAAACTATTTTGCAGAGGTGGAGCAGGCTGCGTTCAACCCCGCCAATATC
GTGCCCGGTATCGGTTTTTCGCCGGACAAGATGCTTCAGGGCCGCCTGTTCTCCTACGGCGATGCACAGCGCTACCGCCT
GGGCGTGAATCACCACCTTATCCCCGTGAATACGGCGCGCTGCCCCTTCCACAGCTATCATCGCGATGGTCAGATGCGCG
TGGACGGCAACTATGGCGGCCATACCAACTATGAGCCCAACAGTTACGGCGCCTGGCAGGAACAGCCTGAAACTGCGGAA
CCGCCCCTGAAAATCAATGGCGACGCCGACCACTGGTCCTACCCTTGCGATGACGCGGACTACTTCGAGCAGCCGGGCAA
ACTGTTCCGCCTGATGACGCCGGAACAGCAGGAGGCACTGTTTGGCAATACGGCCCGCAACCTTGGTGATGCCCCCAGGG
AAATAAAGCTGCGGCACATCCGCAACTGCGCCAAGGCCGATGCGGCCTACGGCGCGGGAGTGGCCAGGGCCTGCGGCATT
GACCCCGCAGAAATATAG

Upstream 100 bases:

>100_bases
CATATGGGCCTATCCATGTCATCTTCCTGCAAGAGGCGGTCACTGAGTCCGGGGCCGCAATTTTCCTGGACTGCACAGAC
AAACCAAGGAGACGACCACT

Downstream 100 bases:

>100_bases
AGTCCCGGGCTGTCAGGTCTTACTGATCTGCAGCCCGGCAGTCTGACCCTGGCTTTCTTCTGACACTTCCCGTCCGGCAG
CCTTCCTGTCGGCATGTGCC

Product: Catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MSNDQNKLTNNAGAPVADNNRVLTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITRFTKASL
FSQIGKKTDLFVRFSTVAGERGAADAERDIRGFAIKFYTDEGNFDLVGNNTPVFFLRDPLKFPDLNHVVKRNPRTNMHSA
QDNWDFWSLLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFINADNERFWVKFHFKTQQGIKNLTDAEAQDLVGRDRD
SHQRDLFEHIEKGDFPRWKLFVQVMPETDAEKLPYHPFDLTKVWYHKDVPMYEVGVLELNRNPENYFAEVEQAAFNPANI
VPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHLIPVNTARCPFHSYHRDGQMRVDGNYGGHTNYEPNSYGAWQEQPETAE
PPLKINGDADHWSYPCDDADYFEQPGKLFRLMTPEQQEALFGNTARNLGDAPREIKLRHIRNCAKADAAYGAGVARACGI
DPAEI

Sequences:

>Translated_485_residues
MSNDQNKLTNNAGAPVADNNRVLTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITRFTKASL
FSQIGKKTDLFVRFSTVAGERGAADAERDIRGFAIKFYTDEGNFDLVGNNTPVFFLRDPLKFPDLNHVVKRNPRTNMHSA
QDNWDFWSLLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFINADNERFWVKFHFKTQQGIKNLTDAEAQDLVGRDRD
SHQRDLFEHIEKGDFPRWKLFVQVMPETDAEKLPYHPFDLTKVWYHKDVPMYEVGVLELNRNPENYFAEVEQAAFNPANI
VPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHLIPVNTARCPFHSYHRDGQMRVDGNYGGHTNYEPNSYGAWQEQPETAE
PPLKINGDADHWSYPCDDADYFEQPGKLFRLMTPEQQEALFGNTARNLGDAPREIKLRHIRNCAKADAAYGAGVARACGI
DPAEI
>Mature_484_residues
SNDQNKLTNNAGAPVADNNRVLTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITRFTKASLF
SQIGKKTDLFVRFSTVAGERGAADAERDIRGFAIKFYTDEGNFDLVGNNTPVFFLRDPLKFPDLNHVVKRNPRTNMHSAQ
DNWDFWSLLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFINADNERFWVKFHFKTQQGIKNLTDAEAQDLVGRDRDS
HQRDLFEHIEKGDFPRWKLFVQVMPETDAEKLPYHPFDLTKVWYHKDVPMYEVGVLELNRNPENYFAEVEQAAFNPANIV
PGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHLIPVNTARCPFHSYHRDGQMRVDGNYGGHTNYEPNSYGAWQEQPETAEP
PLKINGDADHWSYPCDDADYFEQPGKLFRLMTPEQQEALFGNTARNLGDAPREIKLRHIRNCAKADAAYGAGVARACGID
PAEI

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=471, Percent_Identity=52.4416135881104, Blast_Score=493, Evalue=1e-139,
Organism=Escherichia coli, GI48994891, Length=491, Percent_Identity=45.4175152749491, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71998444, Length=472, Percent_Identity=51.4830508474576, Blast_Score=473, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=49.7881355932203, Blast_Score=465, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=49.7881355932203, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6320462, Length=485, Percent_Identity=46.1855670103093, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321525, Length=381, Percent_Identity=42.7821522309711, Blast_Score=310, Evalue=4e-85,
Organism=Drosophila melanogaster, GI17981717, Length=471, Percent_Identity=48.8322717622081, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI19920968, Length=399, Percent_Identity=51.3784461152882, Blast_Score=429, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55261; Mature: 55130

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDQNKLTNNAGAPVADNNRVLTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGS
CCCCCHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAYGTFTVTHDITRFTKASLFSQIGKKTDLFVRFSTVAGERGAADAERDIRGFAIKFYTD
CCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHCCCEEEEEEEEC
EGNFDLVGNNTPVFFLRDPLKFPDLNHVVKRNPRTNMHSAQDNWDFWSLLPEALHQVTVV
CCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEE
MSDRGIPASYRHMHGFGSHTFSFINADNERFWVKFHFKTQQGIKNLTDAEAQDLVGRDRD
EECCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECHHHHHHHCCHHHHHHHCCCCC
SHQRDLFEHIEKGDFPRWKLFVQVMPETDAEKLPYHPFDLTKVWYHKDVPMYEVGVLELN
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEC
RNPENYFAEVEQAAFNPANIVPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHLIPVNTAR
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHCCCCCCCCEEECCCCEEEECCCCC
CPFHSYHRDGQMRVDGNYGGHTNYEPNSYGAWQEQPETAEPPLKINGDADHWSYPCDDAD
CCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCH
YFEQPGKLFRLMTPEQQEALFGNTARNLGDAPREIKLRHIRNCAKADAAYGAGVARACGI
HHHCCCCEEEECCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCC
DPAEI
CCCCC
>Mature Secondary Structure 
SNDQNKLTNNAGAPVADNNRVLTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGS
CCCCHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAYGTFTVTHDITRFTKASLFSQIGKKTDLFVRFSTVAGERGAADAERDIRGFAIKFYTD
CCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHCCCEEEEEEEEC
EGNFDLVGNNTPVFFLRDPLKFPDLNHVVKRNPRTNMHSAQDNWDFWSLLPEALHQVTVV
CCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEE
MSDRGIPASYRHMHGFGSHTFSFINADNERFWVKFHFKTQQGIKNLTDAEAQDLVGRDRD
EECCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECHHHHHHHCCHHHHHHHCCCCC
SHQRDLFEHIEKGDFPRWKLFVQVMPETDAEKLPYHPFDLTKVWYHKDVPMYEVGVLELN
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEC
RNPENYFAEVEQAAFNPANIVPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHLIPVNTAR
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHCCCCCCCCEEECCCCEEEECCCCC
CPFHSYHRDGQMRVDGNYGGHTNYEPNSYGAWQEQPETAEPPLKINGDADHWSYPCDDAD
CCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCH
YFEQPGKLFRLMTPEQQEALFGNTARNLGDAPREIKLRHIRNCAKADAAYGAGVARACGI
HHHCCCCEEEECCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCC
DPAEI
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA