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The map label for this gene is yqeV [H]

Identifier: 220904669

GI number: 220904669

Start: 1677162

End: 1678682

Strand: Direct

Name: yqeV [H]

Synonym: Ddes_1401

Alternate gene names: 220904669

Gene position: 1677162-1678682 (Clockwise)

Preceding gene: 220904667

Following gene: 220904671

Centisome position: 58.37

GC content: 61.28

Gene sequence:

>1521_bases
ATGTCTGTCTGGAATTTCTTTTTGGTCACGTTCGGCTGCAAGGTCAATCAGTACGAAACACAGTCCCTGCGTGAAGCGTG
GCAGGGCCTGGGCGGCGTGGAATGCTCCAGCCCCGCCGAGGCAGATGTCATCTGCGTCAACAGTTGTGCCATCACGGCCA
AAGGCGAAAGAGACGCCCGCAACGCAGTTTTTCGCCTGCGGCGCGAAGCGCCGGACGCCCGCCTGATACTCACCGGCTGC
GCGGCGCGTCTGTTCGCTGACTATCGCCCCCGGCCCGGGGCCGCCTGGGCTGCCCCCGACCTGCTGGTTCCGCAGGAACA
TAAAGACCTGCTGTTGCAAGGCCCGTGGAGCAGCGATTTCGCCGGGCCGGACTCCTGCGCCACCGCTTCGGCGACGCTGC
CTGCACAGCACGAAAAAATGCCCTCTCCGTCCGGCAGTGCTCCATTGTTTACTCCCTTCCGCGAGGTGAACCGCCCCCAG
AAAGCCGAGGAACATGCTTCAACCACAATGAATGCGGACACAAACGCCGATGCCGCCAACAGTTTTCCATCTTTCAACAT
TTCCACCTTCAAGCGCGCCCGGCCTGTGCTCAAAGTGCAGGACGGCTGCGCCCACCGCTGCACTTACTGCATCGTGCCGC
TCACACGAGGCAAGCCCCGTAGCCGCCCGGTAGAACATGTGCTGGCCGAAGCCCGCCGCCTGCTGGAATCGGGCCATGTG
GAAATCATGATTTCCGGCATCAATCTGGGACAATACGGACGGGACGCACAGACGGGCGACTTCTGGAACCTGTTGCGCAC
CCTTGACACGGCGTTGGCTCCGGAATTTGCCGGGTTGGCCCGTTTTCGTATCAGCTCTCTGGAGCCGGGCCAGCTGGACG
AGCGCGCGTTGGATATTTTGCGCCATTGCCGCATGCTCTGCCCGCACCTGCACATATCCCTGCAGCATGGCAGCCGCAAC
GTGCTGAAAAGAATGGGCCGCGGACATTATAGCCCCGCCATGCTGGAGGAAGCAGTAAGGGAACTTTCAGCCCACTGGCC
CGCCATGGGGCTTGGCGCGGACATTATCGCGGGCTTTCCGGGAGAGACCGAAAAAGATGTGCAGGAACTCCTAGAGCTTG
TTGCCCGCCTGCCCCTTGGTTACGCACATGTTTTCCCGTACTCGCGCCGTCCCGGAACTGCGGCAGAACGTTTTGAAGGG
CAGATCCCCCACGCGCTCAAGCTGGAGCGCGCGGCCAGGGTGCGGCAGGCTGTTGCCCTGAAGCAAAAAGAATTTCTCAT
GGCACAAATGGCCTTGCCGCGCATGCTGCTGGCTGCGGACATCTCCGGCAGCATACAAAAGGCCCCTCAAGCGGGCGGCA
AAAAAATCAAGGGCGTCAACGAATATTATGCGGCCTGCTTCTTGCGTCCACGGGAGACGCCCTCCACAGAAGGCGGGGTT
TCCGCTCCCTCGCTTGCCGGGCTTTTGCCCGTGCGGCCAGTGGAGCTGTCAGACAAGGGACTGATCGTGGAACCATTATA
A

Upstream 100 bases:

>100_bases
CCCATCAGAAAGGTGGATAATTTCTTTATGTGACACTTCATGTACCAAGCCTACCCGCGCTCCGCTTGTCAAGGCAAGCG
CTTTTGCGTACACCAGCGCC

Downstream 100 bases:

>100_bases
CCTTGACCACTCGAGAGCGGGCGTTTCCGGCCGCACCCGGCCCATGAAATAGCAGACGCCCCGCGAAGTTCGCGGGGCGT
CTGCTATTATCCGAAGTTTT

Product: MiaB family RNA modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSVWNFFLVTFGCKVNQYETQSLREAWQGLGGVECSSPAEADVICVNSCAITAKGERDARNAVFRLRREAPDARLILTGC
AARLFADYRPRPGAAWAAPDLLVPQEHKDLLLQGPWSSDFAGPDSCATASATLPAQHEKMPSPSGSAPLFTPFREVNRPQ
KAEEHASTTMNADTNADAANSFPSFNISTFKRARPVLKVQDGCAHRCTYCIVPLTRGKPRSRPVEHVLAEARRLLESGHV
EIMISGINLGQYGRDAQTGDFWNLLRTLDTALAPEFAGLARFRISSLEPGQLDERALDILRHCRMLCPHLHISLQHGSRN
VLKRMGRGHYSPAMLEEAVRELSAHWPAMGLGADIIAGFPGETEKDVQELLELVARLPLGYAHVFPYSRRPGTAAERFEG
QIPHALKLERAARVRQAVALKQKEFLMAQMALPRMLLAADISGSIQKAPQAGGKKIKGVNEYYAACFLRPRETPSTEGGV
SAPSLAGLLPVRPVELSDKGLIVEPL

Sequences:

>Translated_506_residues
MSVWNFFLVTFGCKVNQYETQSLREAWQGLGGVECSSPAEADVICVNSCAITAKGERDARNAVFRLRREAPDARLILTGC
AARLFADYRPRPGAAWAAPDLLVPQEHKDLLLQGPWSSDFAGPDSCATASATLPAQHEKMPSPSGSAPLFTPFREVNRPQ
KAEEHASTTMNADTNADAANSFPSFNISTFKRARPVLKVQDGCAHRCTYCIVPLTRGKPRSRPVEHVLAEARRLLESGHV
EIMISGINLGQYGRDAQTGDFWNLLRTLDTALAPEFAGLARFRISSLEPGQLDERALDILRHCRMLCPHLHISLQHGSRN
VLKRMGRGHYSPAMLEEAVRELSAHWPAMGLGADIIAGFPGETEKDVQELLELVARLPLGYAHVFPYSRRPGTAAERFEG
QIPHALKLERAARVRQAVALKQKEFLMAQMALPRMLLAADISGSIQKAPQAGGKKIKGVNEYYAACFLRPRETPSTEGGV
SAPSLAGLLPVRPVELSDKGLIVEPL
>Mature_505_residues
SVWNFFLVTFGCKVNQYETQSLREAWQGLGGVECSSPAEADVICVNSCAITAKGERDARNAVFRLRREAPDARLILTGCA
ARLFADYRPRPGAAWAAPDLLVPQEHKDLLLQGPWSSDFAGPDSCATASATLPAQHEKMPSPSGSAPLFTPFREVNRPQK
AEEHASTTMNADTNADAANSFPSFNISTFKRARPVLKVQDGCAHRCTYCIVPLTRGKPRSRPVEHVLAEARRLLESGHVE
IMISGINLGQYGRDAQTGDFWNLLRTLDTALAPEFAGLARFRISSLEPGQLDERALDILRHCRMLCPHLHISLQHGSRNV
LKRMGRGHYSPAMLEEAVRELSAHWPAMGLGADIIAGFPGETEKDVQELLELVARLPLGYAHVFPYSRRPGTAAERFEGQ
IPHALKLERAARVRQAVALKQKEFLMAQMALPRMLLAADISGSIQKAPQAGGKKIKGVNEYYAACFLRPRETPSTEGGVS
APSLAGLLPVRPVELSDKGLIVEPL

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI28872784, Length=432, Percent_Identity=27.5462962962963, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI28872782, Length=432, Percent_Identity=27.5462962962963, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI93277076, Length=223, Percent_Identity=32.7354260089686, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1786882, Length=438, Percent_Identity=24.8858447488584, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787057, Length=461, Percent_Identity=25.3796095444685, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17553146, Length=430, Percent_Identity=26.9767441860465, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71996771, Length=207, Percent_Identity=31.4009661835749, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21356207, Length=437, Percent_Identity=28.1464530892449, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19922432, Length=226, Percent_Identity=31.858407079646, Blast_Score=96, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 55406; Mature: 55275

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVWNFFLVTFGCKVNQYETQSLREAWQGLGGVECSSPAEADVICVNSCAITAKGERDAR
CCHHHEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECEEEEECCCCHHH
NAVFRLRREAPDARLILTGCAARLFADYRPRPGAAWAAPDLLVPQEHKDLLLQGPWSSDF
HHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
AGPDSCATASATLPAQHEKMPSPSGSAPLFTPFREVNRPQKAEEHASTTMNADTNADAAN
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCC
SFPSFNISTFKRARPVLKVQDGCAHRCTYCIVPLTRGKPRSRPVEHVLAEARRLLESGHV
CCCCCCHHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCE
EIMISGINLGQYGRDAQTGDFWNLLRTLDTALAPEFAGLARFRISSLEPGQLDERALDIL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHH
RHCRMLCPHLHISLQHGSRNVLKRMGRGHYSPAMLEEAVRELSAHWPAMGLGADIIAGFP
HHHHHHCCHHEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
GETEKDVQELLELVARLPLGYAHVFPYSRRPGTAAERFEGQIPHALKLERAARVRQAVAL
CCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
KQKEFLMAQMALPRMLLAADISGSIQKAPQAGGKKIKGVNEYYAACFLRPRETPSTEGGV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHEECCCCCCCCCCCC
SAPSLAGLLPVRPVELSDKGLIVEPL
CCCHHHCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
SVWNFFLVTFGCKVNQYETQSLREAWQGLGGVECSSPAEADVICVNSCAITAKGERDAR
CHHHEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECEEEEECCCCHHH
NAVFRLRREAPDARLILTGCAARLFADYRPRPGAAWAAPDLLVPQEHKDLLLQGPWSSDF
HHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
AGPDSCATASATLPAQHEKMPSPSGSAPLFTPFREVNRPQKAEEHASTTMNADTNADAAN
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCC
SFPSFNISTFKRARPVLKVQDGCAHRCTYCIVPLTRGKPRSRPVEHVLAEARRLLESGHV
CCCCCCHHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCE
EIMISGINLGQYGRDAQTGDFWNLLRTLDTALAPEFAGLARFRISSLEPGQLDERALDIL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHH
RHCRMLCPHLHISLQHGSRNVLKRMGRGHYSPAMLEEAVRELSAHWPAMGLGADIIAGFP
HHHHHHCCHHEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
GETEKDVQELLELVARLPLGYAHVFPYSRRPGTAAERFEGQIPHALKLERAARVRQAVAL
CCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
KQKEFLMAQMALPRMLLAADISGSIQKAPQAGGKKIKGVNEYYAACFLRPRETPSTEGGV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHEECCCCCCCCCCCC
SAPSLAGLLPVRPVELSDKGLIVEPL
CCCHHHCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]