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The map label for this gene is macB [H]

Identifier: 220904661

GI number: 220904661

Start: 1668120

End: 1669310

Strand: Reverse

Name: macB [H]

Synonym: Ddes_1393

Alternate gene names: 220904661

Gene position: 1669310-1668120 (Counterclockwise)

Preceding gene: 220904662

Following gene: 220904660

Centisome position: 58.09

GC content: 57.18

Gene sequence:

>1191_bases
ATGATTGCCATGTCCGACCTTTTCCGCGTCAGCCTGCGTCAGGTTGTACGCCAGCGCGGCTTCGGGGTGATATTGTCCAT
CGCCCTGGGCATCACGGCCTTTATTGTTCTGGCCGTGCTTGGGCGTGAAATACGCTATAAAGTCGGACAAGATATGGTAC
TTATGGGCGGGGTTAACGTCATCCGCGTCTATATGGATGATGCCCAGTACCCCGGCCAGCCCATGCGCGGTTTTTATCCT
GAAACCGTAGACGCCCTGAGCCATCTGCCCGGGGTCTATATGGTGAGCCAGAACATACGCGAAGGAAAAGGCTTTTCTCT
GCGCGGCGCCGGCGAGCGTGTTCTCAATGTAGGCTTTATCGGCATTGACCAGTATTTTTCAGACGTTTTCTCTCTGGCTC
TGGTCGCCGGGCGGCTCATGGATGCTGACGATGTGACCGGCCACAAGCGTGTCTGCATGCTCGGCCGCGAAGCCGCCCAG
GATCTGTACGGAGATGCAGATGCGGCTGTGGGCAAGCTGCTTTTTTTACAGCAGGATGTTTTTGAAGTGGTGGGAGTGGT
CAGCGGGGTCATGCTTGGCAGTTGGTCGCAAGGGGGCTTTTTGCCCTATACCACAATGATTGACAGGAACTGGGCCGGTG
ACAAGGTTACGCGGCTTTTTGTACGCGCCATCGGCTGGCAGGATGTGCCGCCCCTGGTCAAGGAAATTCCTGAAGTTGTT
CAGGAATTTCAGACTGCGCCCTACCTTGTAGTGCATACGCAGGATGATCAGCTGGCGCGTATCCAGGATACTTTTTTATG
GGTTGAAGTGCTGCTTTGGCTCGGTATTGCCGCGTCGCTCATGCTTGGCGGCTTCGGCATATGGTACGGTACGTTTGCCG
CAGTACGCGCCCGCACCCGCGAGGTGGGGCTGAAGAAGGCCATGGGCGGTTCCGATACGGACATTCTGGCCCAGTTTCTT
GCTGAGGCCTTGTGCAAGTCTGTGGCTGGCGGTGTTTTGGGTATTGCCGTAGGCATTGCGCTGGTGGAAGGGGGCTCCTG
GTCGCTGGGTACGGGTATCTCTTATTCCCTGCTTTTAGCCAGCAGCCTGGGCAGCATTGTTTTTTCCGCAGTCATCGGCG
TGGCGGGGGGCCTGTATCCGGCCATCCAGGCCAGCCGCATGGACGTGGTCACGGCTCTGCGCTTTGAGTAA

Upstream 100 bases:

>100_bases
GGACGAAAGCGCACAACAGTTCGCATGAGGCGGTGTCGGCGCGGTTTGTCATGCCGTGTCCGGTGCAATTGTACAGGGAT
ATTCTTACAGTGGTTTTGCC

Downstream 100 bases:

>100_bases
AAACAGATGGCGGCCCAGCCCTGACCGCTGCTGCGGCGGCCCGGGCCGTTTATGGACAGGGTGATTCATGGCTCCTGTTA
TTGTCGCCAAAGATTTGTAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MIAMSDLFRVSLRQVVRQRGFGVILSIALGITAFIVLAVLGREIRYKVGQDMVLMGGVNVIRVYMDDAQYPGQPMRGFYP
ETVDALSHLPGVYMVSQNIREGKGFSLRGAGERVLNVGFIGIDQYFSDVFSLALVAGRLMDADDVTGHKRVCMLGREAAQ
DLYGDADAAVGKLLFLQQDVFEVVGVVSGVMLGSWSQGGFLPYTTMIDRNWAGDKVTRLFVRAIGWQDVPPLVKEIPEVV
QEFQTAPYLVVHTQDDQLARIQDTFLWVEVLLWLGIAASLMLGGFGIWYGTFAAVRARTREVGLKKAMGGSDTDILAQFL
AEALCKSVAGGVLGIAVGIALVEGGSWSLGTGISYSLLLASSLGSIVFSAVIGVAGGLYPAIQASRMDVVTALRFE

Sequences:

>Translated_396_residues
MIAMSDLFRVSLRQVVRQRGFGVILSIALGITAFIVLAVLGREIRYKVGQDMVLMGGVNVIRVYMDDAQYPGQPMRGFYP
ETVDALSHLPGVYMVSQNIREGKGFSLRGAGERVLNVGFIGIDQYFSDVFSLALVAGRLMDADDVTGHKRVCMLGREAAQ
DLYGDADAAVGKLLFLQQDVFEVVGVVSGVMLGSWSQGGFLPYTTMIDRNWAGDKVTRLFVRAIGWQDVPPLVKEIPEVV
QEFQTAPYLVVHTQDDQLARIQDTFLWVEVLLWLGIAASLMLGGFGIWYGTFAAVRARTREVGLKKAMGGSDTDILAQFL
AEALCKSVAGGVLGIAVGIALVEGGSWSLGTGISYSLLLASSLGSIVFSAVIGVAGGLYPAIQASRMDVVTALRFE
>Mature_396_residues
MIAMSDLFRVSLRQVVRQRGFGVILSIALGITAFIVLAVLGREIRYKVGQDMVLMGGVNVIRVYMDDAQYPGQPMRGFYP
ETVDALSHLPGVYMVSQNIREGKGFSLRGAGERVLNVGFIGIDQYFSDVFSLALVAGRLMDADDVTGHKRVCMLGREAAQ
DLYGDADAAVGKLLFLQQDVFEVVGVVSGVMLGSWSQGGFLPYTTMIDRNWAGDKVTRLFVRAIGWQDVPPLVKEIPEVV
QEFQTAPYLVVHTQDDQLARIQDTFLWVEVLLWLGIAASLMLGGFGIWYGTFAAVRARTREVGLKKAMGGSDTDILAQFL
AEALCKSVAGGVLGIAVGIALVEGGSWSLGTGISYSLLLASSLGSIVFSAVIGVAGGLYPAIQASRMDVVTALRFE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=363, Percent_Identity=25.6198347107438, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42720; Mature: 42720

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAMSDLFRVSLRQVVRQRGFGVILSIALGITAFIVLAVLGREIRYKVGQDMVLMGGVNV
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEE
IRVYMDDAQYPGQPMRGFYPETVDALSHLPGVYMVSQNIREGKGFSLRGAGERVLNVGFI
EEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCEEEEEEE
GIDQYFSDVFSLALVAGRLMDADDVTGHKRVCMLGREAAQDLYGDADAAVGKLLFLQQDV
EHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FEVVGVVSGVMLGSWSQGGFLPYTTMIDRNWAGDKVTRLFVRAIGWQDVPPLVKEIPEVV
HHHHHHHHHHHHCCCCCCCCCCCHHEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
QEFQTAPYLVVHTQDDQLARIQDTFLWVEVLLWLGIAASLMLGGFGIWYGTFAAVRARTR
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVGLKKAMGGSDTDILAQFLAEALCKSVAGGVLGIAVGIALVEGGSWSLGTGISYSLLLA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SSLGSIVFSAVIGVAGGLYPAIQASRMDVVTALRFE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAMSDLFRVSLRQVVRQRGFGVILSIALGITAFIVLAVLGREIRYKVGQDMVLMGGVNV
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEE
IRVYMDDAQYPGQPMRGFYPETVDALSHLPGVYMVSQNIREGKGFSLRGAGERVLNVGFI
EEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCEEEEEEE
GIDQYFSDVFSLALVAGRLMDADDVTGHKRVCMLGREAAQDLYGDADAAVGKLLFLQQDV
EHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FEVVGVVSGVMLGSWSQGGFLPYTTMIDRNWAGDKVTRLFVRAIGWQDVPPLVKEIPEVV
HHHHHHHHHHHHCCCCCCCCCCCHHEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
QEFQTAPYLVVHTQDDQLARIQDTFLWVEVLLWLGIAASLMLGGFGIWYGTFAAVRARTR
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVGLKKAMGGSDTDILAQFLAEALCKSVAGGVLGIAVGIALVEGGSWSLGTGISYSLLLA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SSLGSIVFSAVIGVAGGLYPAIQASRMDVVTALRFE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA