Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 220904553

GI number: 220904553

Start: 1514309

End: 1515178

Strand: Reverse

Name: ppnK [H]

Synonym: Ddes_1284

Alternate gene names: 220904553

Gene position: 1515178-1514309 (Counterclockwise)

Preceding gene: 220904562

Following gene: 220904552

Centisome position: 52.73

GC content: 56.9

Gene sequence:

>870_bases
ATGCAAAATCAACTCAAGCGCCACATTCTACTGGTCTGCAAGGCCCGCCACGAACGCGCCGCCCAACTGGGTGAAGAAAT
TCGCGCGTGGCTTGAAGAGCGTGGTCACAAAGCACATCTTGTAGAGGCCGGGCTGGACTCTTCCCTTTACACGGATGCCC
TTGACTTTGTTGTGGTGCTTGGCGGTGACGGCACCATGCTCGGGGTCGCCCGGCGCCTTGTGGGTAGTGATGTGCCGGTG
CTGGGTATCAACTTCGGGCGTGTCGGTTTTCTTACAGATGCCCAGCCGGAAAACTGGCGCGAAAAGCTTGCCGAATGTCT
GGATGGACACGAGCCGGTTCGCTCCTGTATGGCACTTAGCTGGTCGCTTGTACGCGACGGCGAAGAAATTCAGGGCGGGG
CGGCGGTTAATGACGTGGTTGTCAGCCGGGGTTCCCTGTCCAGGCTGGTCTGCCTTGATATATGGGTTGACGGGCAACGC
ATGGGGTCGTTGCGCAGCGACGGCATCATATTGTGTACGCCTGTGGGCAGTTCGGGCTACAGCGTATCCGCTGGCGGCCC
GCTTCTTTATCCTGCTATGGATGCCATCGGCTTCACGCCTGTGTGCCCTTTTTTGAATACTATTTCCCCCATGGTATTTC
CCGGATCGACAGACATAGAGCTTCAGATATTGCGCGGCTCTACGGACTGCTATCTTACGGTGGACGGGCAGGAAGGGCAT
AAACTGAAAAAAGACGACCTTGTGCGTATTTCCGGCCTGCCTGCGGCAGTGCGTTTTATGGGAGAAGGCACATGCTTTTT
TGAGCGCCTGCGCAGCCGAGGTTTTGTCTTGCAGGGATCTGTGGGGAACTGTACGGGGGAAATGCTGTGA

Upstream 100 bases:

>100_bases
TTTGGCTAGGAAGTTTCTGTTCATATGTCAAAGCGCCGGCCCTGACAAGTAAGGCCGGCGGGCTTGCGGTAAGAGCCTTG
ATAACGTAAATTGTCACCTT

Downstream 100 bases:

>100_bases
ACAAGGCTCTTGCGCCTGCAAAGGTGTGCGATATCCGTCTGGGACAAAATGTTCGTTTTGATGCATGGCTGTACAGCATG
CTCATGGATAACAATCTTGC

Product: ATP-NAD/AcoX kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MQNQLKRHILLVCKARHERAAQLGEEIRAWLEERGHKAHLVEAGLDSSLYTDALDFVVVLGGDGTMLGVARRLVGSDVPV
LGINFGRVGFLTDAQPENWREKLAECLDGHEPVRSCMALSWSLVRDGEEIQGGAAVNDVVVSRGSLSRLVCLDIWVDGQR
MGSLRSDGIILCTPVGSSGYSVSAGGPLLYPAMDAIGFTPVCPFLNTISPMVFPGSTDIELQILRGSTDCYLTVDGQEGH
KLKKDDLVRISGLPAAVRFMGEGTCFFERLRSRGFVLQGSVGNCTGEML

Sequences:

>Translated_289_residues
MQNQLKRHILLVCKARHERAAQLGEEIRAWLEERGHKAHLVEAGLDSSLYTDALDFVVVLGGDGTMLGVARRLVGSDVPV
LGINFGRVGFLTDAQPENWREKLAECLDGHEPVRSCMALSWSLVRDGEEIQGGAAVNDVVVSRGSLSRLVCLDIWVDGQR
MGSLRSDGIILCTPVGSSGYSVSAGGPLLYPAMDAIGFTPVCPFLNTISPMVFPGSTDIELQILRGSTDCYLTVDGQEGH
KLKKDDLVRISGLPAAVRFMGEGTCFFERLRSRGFVLQGSVGNCTGEML
>Mature_289_residues
MQNQLKRHILLVCKARHERAAQLGEEIRAWLEERGHKAHLVEAGLDSSLYTDALDFVVVLGGDGTMLGVARRLVGSDVPV
LGINFGRVGFLTDAQPENWREKLAECLDGHEPVRSCMALSWSLVRDGEEIQGGAAVNDVVVSRGSLSRLVCLDIWVDGQR
MGSLRSDGIILCTPVGSSGYSVSAGGPLLYPAMDAIGFTPVCPFLNTISPMVFPGSTDIELQILRGSTDCYLTVDGQEGH
KLKKDDLVRISGLPAAVRFMGEGTCFFERLRSRGFVLQGSVGNCTGEML

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=230, Percent_Identity=26.9565217391304, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1788968, Length=249, Percent_Identity=34.136546184739, Blast_Score=145, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322509, Length=219, Percent_Identity=30.1369863013699, Blast_Score=116, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320794, Length=236, Percent_Identity=29.2372881355932, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325068, Length=206, Percent_Identity=30.0970873786408, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI161077047, Length=220, Percent_Identity=30.4545454545455, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573830, Length=220, Percent_Identity=30.4545454545455, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573832, Length=220, Percent_Identity=30.4545454545455, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573828, Length=220, Percent_Identity=30.4545454545455, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573826, Length=220, Percent_Identity=30.4545454545455, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281363321, Length=281, Percent_Identity=27.0462633451957, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363323, Length=281, Percent_Identity=27.0462633451957, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24653422, Length=245, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24653424, Length=281, Percent_Identity=27.0462633451957, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129957, Length=281, Percent_Identity=27.0462633451957, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 31250; Mature: 31250

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNQLKRHILLVCKARHERAAQLGEEIRAWLEERGHKAHLVEAGLDSSLYTDALDFVVVL
CCCHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCEEEEEEE
GGDGTMLGVARRLVGSDVPVLGINFGRVGFLTDAQPENWREKLAECLDGHEPVRSCMALS
CCCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHH
WSLVRDGEEIQGGAAVNDVVVSRGSLSRLVCLDIWVDGQRMGSLRSDGIILCTPVGSSGY
HHHHCCCHHHCCCCHHHHHHHCCCCCCEEEEEEEEECCHHHCCCCCCCEEEEEECCCCCC
SVSAGGPLLYPAMDAIGFTPVCPFLNTISPMVFPGSTDIELQILRGSTDCYLTVDGQEGH
EECCCCCCHHHHHHHCCCCCHHHHHHHCCCEEECCCCCEEEEEEECCCEEEEEEECCCCC
KLKKDDLVRISGLPAAVRFMGEGTCFFERLRSRGFVLQGSVGNCTGEML
CCCCCCEEEEECCCCEEHEECCCHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MQNQLKRHILLVCKARHERAAQLGEEIRAWLEERGHKAHLVEAGLDSSLYTDALDFVVVL
CCCHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCEEEEEEE
GGDGTMLGVARRLVGSDVPVLGINFGRVGFLTDAQPENWREKLAECLDGHEPVRSCMALS
CCCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHH
WSLVRDGEEIQGGAAVNDVVVSRGSLSRLVCLDIWVDGQRMGSLRSDGIILCTPVGSSGY
HHHHCCCHHHCCCCHHHHHHHCCCCCCEEEEEEEEECCHHHCCCCCCCEEEEEECCCCCC
SVSAGGPLLYPAMDAIGFTPVCPFLNTISPMVFPGSTDIELQILRGSTDCYLTVDGQEGH
EECCCCCCHHHHHHHCCCCCHHHHHHHCCCEEECCCCCEEEEEEECCCEEEEEEECCCCC
KLKKDDLVRISGLPAAVRFMGEGTCFFERLRSRGFVLQGSVGNCTGEML
CCCCCCEEEEECCCCEEHEECCCHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA