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The map label for this gene is dtd

Identifier: 220904523

GI number: 220904523

Start: 1474360

End: 1474842

Strand: Direct

Name: dtd

Synonym: Ddes_1254

Alternate gene names: 220904523

Gene position: 1474360-1474842 (Clockwise)

Preceding gene: 220904522

Following gene: 220904524

Centisome position: 51.31

GC content: 55.49

Gene sequence:

>483_bases
ATGCGCATACTGGTGCAAAGAGTTACTGAAGCTTCCGTGAACGTCGATGGCCGTCAGGTGGCGGCCATCGGCCCCGGCAT
CATGGCTCTGGTGGGCTTCGGCCAGGAAGACGGCCCGGACTTTCACAACAGACCGGCTTTTCGGGGTATGGCCCAAAAAC
TGGCCGGTTTGCGGATTTTTCCCGGCCAGGGAGAACTTGCCAACAAATTTCATACATCACTTGAAGAATTCGGCGGGCAG
CTTTTACTCGTACCGCAGTTTACCCTGTATGCAGACTGCCGCAAGGGCCGCCGTCCGTCCTTTACAGATGCAGGTAATCC
GGCATGGGCGGAACCAATGTTTGAACATTTCGTGAAGATAGTTGACGAATCTTGCAGCGTCAGCGTATCTTCAGGTATCT
TCGGCGCCGACATGGCGGTGCGCCTTTGCAATTGGGGTCCTGTCACCATCTGGCTTGACTCGCTCAGCCTGTTTGGCAGT
TGA

Upstream 100 bases:

>100_bases
GCGAAGAAGAAGAAAGCAAGGCCGCCAGTCGCAAGCAGCGCAAGGCAAAAAATGTGACGACTGCAGAAAACGGCCAGGAA
CAACCTCAAGAGAATGCCTG

Downstream 100 bases:

>100_bases
CGCCCGCCCACCCAGGAGGCCCGGCCCCGTGTTTACCCTGCAAGCGGAGTCTCATAAAAACGTTACAGTCCTGCGCTATC
TGGGCGATATGCTGTTGCCT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRILVQRVTEASVNVDGRQVAAIGPGIMALVGFGQEDGPDFHNRPAFRGMAQKLAGLRIFPGQGELANKFHTSLEEFGGQ
LLLVPQFTLYADCRKGRRPSFTDAGNPAWAEPMFEHFVKIVDESCSVSVSSGIFGADMAVRLCNWGPVTIWLDSLSLFGS

Sequences:

>Translated_160_residues
MRILVQRVTEASVNVDGRQVAAIGPGIMALVGFGQEDGPDFHNRPAFRGMAQKLAGLRIFPGQGELANKFHTSLEEFGGQ
LLLVPQFTLYADCRKGRRPSFTDAGNPAWAEPMFEHFVKIVDESCSVSVSSGIFGADMAVRLCNWGPVTIWLDSLSLFGS
>Mature_160_residues
MRILVQRVTEASVNVDGRQVAAIGPGIMALVGFGQEDGPDFHNRPAFRGMAQKLAGLRIFPGQGELANKFHTSLEEFGGQ
LLLVPQFTLYADCRKGRRPSFTDAGNPAWAEPMFEHFVKIVDESCSVSVSSGIFGADMAVRLCNWGPVTIWLDSLSLFGS

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=155, Percent_Identity=36.1290322580645, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1790320, Length=155, Percent_Identity=38.7096774193548, Blast_Score=107, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI115533292, Length=155, Percent_Identity=30.9677419354839, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319982, Length=155, Percent_Identity=36.7741935483871, Blast_Score=98, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281361569, Length=155, Percent_Identity=34.8387096774194, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_DESDA (B8J080)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479835.1
- GeneID:   7284939
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1254
- HOGENOM:   HBG286048
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 17403; Mature: 17403

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: ACT_SITE 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVQRVTEASVNVDGRQVAAIGPGIMALVGFGQEDGPDFHNRPAFRGMAQKLAGLRIF
CCHHHHHHHHHCCCCCCCEEEEECCCHHEEEECCCCCCCCCCCCCHHHHHHHHHCCEEEE
PGQGELANKFHTSLEEFGGQLLLVPQFTLYADCRKGRRPSFTDAGNPAWAEPMFEHFVKI
CCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
VDESCSVSVSSGIFGADMAVRLCNWGPVTIWLDSLSLFGS
HCCCCCEEECCCCCCHHHHHEECCCCCEEEEEECHHHHCC
>Mature Secondary Structure
MRILVQRVTEASVNVDGRQVAAIGPGIMALVGFGQEDGPDFHNRPAFRGMAQKLAGLRIF
CCHHHHHHHHHCCCCCCCEEEEECCCHHEEEECCCCCCCCCCCCCHHHHHHHHHCCEEEE
PGQGELANKFHTSLEEFGGQLLLVPQFTLYADCRKGRRPSFTDAGNPAWAEPMFEHFVKI
CCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
VDESCSVSVSSGIFGADMAVRLCNWGPVTIWLDSLSLFGS
HCCCCCEEECCCCCCHHHHHEECCCCCEEEEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA