Click here to switch to the map view.

The map label for this gene is glpX [H]

Identifier: 218906512

GI number: 218906512

Start: 5120769

End: 5121560

Strand: Reverse

Name: glpX [H]

Synonym: BCAH820_5426

Alternate gene names: 218906512

Gene position: 5121560-5120769 (Counterclockwise)

Preceding gene: 218906513

Following gene: 218906511

Centisome position: 96.58

GC content: 43.43

Gene sequence:

>792_bases
GTGGAAAGAAGTTTATCTATGGAGTTAGTACGTGTAACAGAGGCTGCAGCTTTATCATCAGCGCGTTGGATGGGACGCGG
GAAAAAGGATGAGGCAGACGGTGCAGCAACATCAGCTATGCGTGATGTATTTGATACAATTCCGATGAAAGGTACAGTTG
TAATTGGTGAAGGTGAAATGGATGAAGCACCAATGCTATATATCGGAGAAAAATTAGGTACAGGATATGGTCCGCGTGTA
GACGTTGCAGTTGATCCTTTAGAAGGGACAAACATTGTAGCAGCTGGTGGATGGAATGCTCTTGCCGTTATTGCAATTGC
AGATCACGGTAATTTGTTACATGCTCCTGACATGTACATGGATAAAATCGCGGTTGGCCCAGAAGCGGTTGGGGCGGTCG
ATATTGATGCGCCTATTATCGATAACTTACGTGCAGTTGCGAAAGCGAAAAACAAAGATATTGAAGATGTTGTAGCGACA
GTTTTAAACCGTCCACGTCATCAAGCAATTATTGAAGAAATTCGTAAAGCTGGTGCTCGTATTAAATTGATTAATGATGG
AGACGTAGCAGGTGCAATTAATACTGCATTTGATCGTACAGGTGTAGATATTTTATTCGGATCTGGTGGTGCGCCTGAGG
GCGTATTAGCAGCAGTTGCATTAAAATGTTTAGGTGGCGAGATTCACGGGAAATTATTACCACAAAACGAAGCTGAATTG
GCGCGTTTGCAAAAAGATGGGCATAGAAGACATCAACCGCATCCTTCGCATGGAGGACTTAGTAAAAGGTGA

Upstream 100 bases:

>100_bases
GGGAAGCGAAGCATCACTACTTGCGGAAGTACACTTTATAGAAAAAACACGGTTCACAAAATACGGCAGAAATATAAAGA
CTTAAAGGAGAGGGATTATC

Downstream 100 bases:

>100_bases
CGATGCAATCTTCGCAGCAACAGGCGTAACAGACGGAGAACTACTACGCGGCGTTCAATTTAAAGGTAGCGTAGGAACAA
CACAATCTCTTGTTATGCGT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEMDEAPMLYIGEKLGTGYGPRV
DVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYMDKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVAT
VLNRPRHQAIIEEIRKAGARIKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
ARLQKDGHRRHQPHPSHGGLSKR

Sequences:

>Translated_263_residues
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEMDEAPMLYIGEKLGTGYGPRV
DVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYMDKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVAT
VLNRPRHQAIIEEIRKAGARIKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
ARLQKDGHRRHQPHPSHGGLSKR
>Mature_263_residues
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEMDEAPMLYIGEKLGTGYGPRV
DVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYMDKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVAT
VLNRPRHQAIIEEIRKAGARIKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
ARLQKDGHRRHQPHPSHGGLSKR

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=239, Percent_Identity=51.8828451882845, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1789298, Length=236, Percent_Identity=47.8813559322034, Blast_Score=217, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 27754; Mature: 27754

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEM
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
DEAPMLYIGEKLGTGYGPRVDVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYM
CCCCEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCEEECCCHHH
DKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVATVLNRPRHQAIIEEIRKAGAR
HHHHCCCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCE
IKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
EEEEECCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCHHCCCCCCCCHHHH
ARLQKDGHRRHQPHPSHGGLSKR
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEM
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
DEAPMLYIGEKLGTGYGPRVDVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYM
CCCCEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCEEECCCHHH
DKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVATVLNRPRHQAIIEEIRKAGAR
HHHHCCCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCE
IKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
EEEEECCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCHHCCCCCCCCHHHH
ARLQKDGHRRHQPHPSHGGLSKR
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]