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The map label for this gene is ispH [H]

Identifier: 218905425

GI number: 218905425

Start: 4096405

End: 4097355

Strand: Direct

Name: ispH [H]

Synonym: BCAH820_4310

Alternate gene names: 218905425

Gene position: 4096405-4097355 (Clockwise)

Preceding gene: 218905424

Following gene: 218905459

Centisome position: 77.25

GC content: 38.17

Gene sequence:

>951_bases
ATGAAAATTGTTAAAATTTCCCCTCGTGGTTATTGCTACGGTGTTGTGGATGCGATGGTTATTGCACGTAACGCCGCATT
AGATACATCATTACCAAGACCTATTTATATTTTAGGTATGATTGTTCACAACAAACATGTAACAGATGCATTCGAAGAAG
ATGGCATCATCACTTTAGACGGTCCAAGTCGATTAGACATTTTAGATAAAATCGATTCTGGTACTGTTATTTTCACTGCA
CACGGTGTTTCTCCAGAAGTTAAACAACGTGCAAAAGAAAAAGGTTTAACAACAATCGATGCCACTTGTCCAGATGTTAC
AAAAACACATGACCTTATTGAAGCAAAGAAAGCTGAAGGTTACCATGTCATTTATATCGGCAAAAAAAATCATCCAGAAC
CGGAAGGCGCAGTTGGTATCGCACCTGATATCGTTCACCTTATCGAAAGAGCCGATGATTTAAAAACATTAGAAATTCCA
ACGGATAAAATTTTAGTTACAAATCAAACAACGATGAGCCAATGGGATGTGCAACATTTAATGGAGGACATTCAGAAAAA
ATTCCCAACAGCAGAGTTCCATAAGGAAATTTGTTTAGCAACTCAAGTTCGCCAAGAAGCTGTTGCCAAACAAGCTGATG
TTGCCGACTTAACAATTGTTGTTGGTGATCCGAAAAGTAACAACTCAAACCGTTTAGCACAAGTATCACAAGAAATCGCT
GGTACGAAGGCATACCGCGTTGCAGACGTAAGTGAAATTAATTTAGAATGGTTACAAGGTGTAGAAAACGTAGCTGTTAC
AGCAGGTGCTTCTACTCCAACACCAATTACAAAAGAGGTTATCGCTTTCTTAGAGCAATATGACCCAATGAATCCCGCTA
CATGGGAGAGAGTTCGAAAAGTACCGTTACAAAAAATATTACCTCGTGTAAAAGTGAAAAAAGAACAATAA

Upstream 100 bases:

>100_bases
TATATGTGTAACAATCCTTTGTTTTCTATCCACTCCTCCTTTATAATGTAAAAGACTATGCACAAAAGTATCCCTTGTTT
AGAAGGAGAGGATTACTCAT

Downstream 100 bases:

>100_bases
TAAAAACCGTTGCCTATATGAGCAACGGTTTTTATTTTTCTTATACAAATGTAAATGGATCTGTATGTAACTGCGAAGCA
TGAATGTTTACATTAAGTTT

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLDILDKIDSGTVIFTA
HGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIP
TDKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIA
GTKAYRVADVSEINLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRKVPLQKILPRVKVKKEQ

Sequences:

>Translated_316_residues
MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLDILDKIDSGTVIFTA
HGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIP
TDKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIA
GTKAYRVADVSEINLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRKVPLQKILPRVKVKKEQ
>Mature_316_residues
MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLDILDKIDSGTVIFTA
HGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIP
TDKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIA
GTKAYRVADVSEINLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRKVPLQKILPRVKVKKEQ

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=292, Percent_Identity=38.013698630137, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34954; Mature: 34954

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLD
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHCCCEEEEC
GPSRLDILDKIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEG
CCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCC
YHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIPTDKILVTNQTTMSQWDVQHL
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHH
MEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHH
GTKAYRVADVSEINLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRK
CCCEEEEECHHHCCHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
VPLQKILPRVKVKKEQ
CCHHHHCCCCCCCCCC
>Mature Secondary Structure
MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLD
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHCCCEEEEC
GPSRLDILDKIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEG
CCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCC
YHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIPTDKILVTNQTTMSQWDVQHL
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHH
MEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHH
GTKAYRVADVSEINLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRK
CCCEEEEECHHHCCHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
VPLQKILPRVKVKKEQ
CCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA