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The map label for this gene is pagR [H]

Identifier: 218905395

GI number: 218905395

Start: 4069758

End: 4070048

Strand: Direct

Name: pagR [H]

Synonym: BCAH820_4279

Alternate gene names: 218905395

Gene position: 4069758-4070048 (Clockwise)

Preceding gene: 218905394

Following gene: 218905398

Centisome position: 76.75

GC content: 32.65

Gene sequence:

>291_bases
ATGTTAGAAACCTTTCAAAAAGAAATAGAACTATATGAAAGCAATGCAGAATTATTGAAAGTACTTGCTCATCCTGTTCG
CTTATGTATTGTAAAAGGATTAATTGAACGTGGTCCAAGCAACGTTTCTACAATGTACACTGGCTTAAACATGCCACAAT
CTACAATTTCACAGCATTTAGCAAAATTAAAAAGTGCTAAAATCGTTTCAAGCGAAAGAAAAGGTTTGGAAATTTATTAC
AAAGTAGAAAACGAGACAATTATTCAACTCGTTCGCGTATTATTGGGTTAG

Upstream 100 bases:

>100_bases
TTTACTTTAGGAATGTTTTTCTGCAACAACTGTTTTCTTTTCTTTAATTTTTTGGTATGTATAGTATGGTATAACAGCTC
ACACGGAGGTGGAAAAAAAC

Downstream 100 bases:

>100_bases
GGACTCATAAACAGAGAAAAAGGACGTATTTTATATTTTTTATCTCATATCTTTAATATAAATATATATCATGAGAGGAA
ATATATGATGCTACATAAGT

Product: transcriptional regulator, ArsR family

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYY
KVENETIIQLVRVLLG

Sequences:

>Translated_96_residues
MLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYY
KVENETIIQLVRVLLG
>Mature_96_residues
MLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGLEIYY
KVENETIIQLVRVLLG

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10845; Mature: 10845

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHL
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHH
AKLKSAKIVSSERKGLEIYYKVENETIIQLVRVLLG
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHC
>Mature Secondary Structure
MLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHL
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHH
AKLKSAKIVSSERKGLEIYYKVENETIIQLVRVLLG
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]