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The map label for this gene is ykvZ [H]

Identifier: 218905346

GI number: 218905346

Start: 4032595

End: 4033572

Strand: Direct

Name: ykvZ [H]

Synonym: BCAH820_4230

Alternate gene names: 218905346

Gene position: 4032595-4033572 (Clockwise)

Preceding gene: 218905345

Following gene: 218905347

Centisome position: 76.05

GC content: 38.14

Gene sequence:

>978_bases
ATGGCCAATATAAAACAAATTGCAAAAACCGCTGGTGTATCCATATCAACTGTTTCTCGTGTCCTGAATAATCACCCTTA
CGTAAAAGAAGAAAAACGTAAGCGTGTTCTAGATGCTGTTGAAGAATTGAACTATGCCAAAAATATAAATGCTATTCATT
TAATAAAGGGCAAAACATATACGATCGGTGTTATGCTCCCTTTCATTAACCTTCCATACTTCAGTACCATTATTGAAGGA
ATCGGTAACGAAGCGTTAGCAGCTGGCTATCACATTAATTTATGTCAAACGAATTACGATAGTATTGAAGAAATTCGTGT
TCTGGAAATGATGAAAATGAAACAATTCGACGGGATGATTATTTGCTCTCGAACAAGTTCATGGGAACAAATTGAACCTT
TCGCAAAATTTGCTCCTATTATTTCATGCGAAAAAATGAACCACCCTCTCATTTCATCCGTCTACGTAGATCATTATGAA
GGATTCCGTCTCGGCACCGCCTATTTACTCAAGAAAGGCCATGAAAAAATCGGAATTTGTTTAGCAAGAAAAACGAGCGC
AAATTCTATGGAGCGCGAAAAGGCGTTTGCTGATACACTTCGTAAGGAGGGCAAAACGTTACATCCCGAATGGATTTTTC
ATCAATGCTATACAATGCAAGACGGTGCACAATTACTCCATCGTATTGTAAATATGAAAAATCGTCCAACCGCTATTTTT
ACAGCAAACGATCAAGTTGCAGCAGGTTTAGTAACAGAAGCTCGAAAACAAGGCCTTCGAGTACCCGAAGACCTTGCTAT
CCTCGGATTTGATAATCATGAAATTTCAAAGGCGTTAGAAATTTCAACAATTGAACATCCCGGTCTCGCAATGGGCTCAC
ATGCGTTTTCTTTATTCCATAAACAAATGCAAAGTGAGCAAATTATCGGGAACGCAAAAGAACTTTCATTCCATTTAATT
GAGCGAGATACTGTCTAA

Upstream 100 bases:

>100_bases
AGAAGTCTTATTCATACCATAGTTTGTGAAAAGCTTTTCAGGTCAAGATTTTTTCTTTCTTATTATTTTCCCTTTATAAT
AAGAGGAAGAGGTGATACAT

Downstream 100 bases:

>100_bases
AAGGAGCGTTACCTATAGCGCTCTTTTTCAGTTCTTCACCTATTGACTTTATATTTTTACTCGCATATAATGAACCTAAC
GAACGGTAGGTAGGGGATGA

Product: sugar-binding transcriptional regulator, LacI family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MANIKQIAKTAGVSISTVSRVLNNHPYVKEEKRKRVLDAVEELNYAKNINAIHLIKGKTYTIGVMLPFINLPYFSTIIEG
IGNEALAAGYHINLCQTNYDSIEEIRVLEMMKMKQFDGMIICSRTSSWEQIEPFAKFAPIISCEKMNHPLISSVYVDHYE
GFRLGTAYLLKKGHEKIGICLARKTSANSMEREKAFADTLRKEGKTLHPEWIFHQCYTMQDGAQLLHRIVNMKNRPTAIF
TANDQVAAGLVTEARKQGLRVPEDLAILGFDNHEISKALEISTIEHPGLAMGSHAFSLFHKQMQSEQIIGNAKELSFHLI
ERDTV

Sequences:

>Translated_325_residues
MANIKQIAKTAGVSISTVSRVLNNHPYVKEEKRKRVLDAVEELNYAKNINAIHLIKGKTYTIGVMLPFINLPYFSTIIEG
IGNEALAAGYHINLCQTNYDSIEEIRVLEMMKMKQFDGMIICSRTSSWEQIEPFAKFAPIISCEKMNHPLISSVYVDHYE
GFRLGTAYLLKKGHEKIGICLARKTSANSMEREKAFADTLRKEGKTLHPEWIFHQCYTMQDGAQLLHRIVNMKNRPTAIF
TANDQVAAGLVTEARKQGLRVPEDLAILGFDNHEISKALEISTIEHPGLAMGSHAFSLFHKQMQSEQIIGNAKELSFHLI
ERDTV
>Mature_324_residues
ANIKQIAKTAGVSISTVSRVLNNHPYVKEEKRKRVLDAVEELNYAKNINAIHLIKGKTYTIGVMLPFINLPYFSTIIEGI
GNEALAAGYHINLCQTNYDSIEEIRVLEMMKMKQFDGMIICSRTSSWEQIEPFAKFAPIISCEKMNHPLISSVYVDHYEG
FRLGTAYLLKKGHEKIGICLARKTSANSMEREKAFADTLRKEGKTLHPEWIFHQCYTMQDGAQLLHRIVNMKNRPTAIFT
ANDQVAAGLVTEARKQGLRVPEDLAILGFDNHEISKALEISTIEHPGLAMGSHAFSLFHKQMQSEQIIGNAKELSFHLIE
RDTV

Specific function: This Protein Negatively Controls The Transcription Initiation Of Genes Such As Deocabd, Udp, And Cdd Encoding Catabolizing Enzymes And Nupc, Nupg, And Tsx Encoding Transporting And Pore-Forming Proteins. Binds Cytidine And Adenosine As Effectors. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=327, Percent_Identity=29.0519877675841, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787948, Length=340, Percent_Identity=29.1176470588235, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=27.1341463414634, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788474, Length=303, Percent_Identity=27.7227722772277, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789068, Length=281, Percent_Identity=28.1138790035587, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=24.1610738255034, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=25.625, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786540, Length=323, Percent_Identity=26.0061919504644, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=25.0793650793651, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787906, Length=263, Percent_Identity=23.9543726235741, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790715, Length=333, Percent_Identity=23.7237237237237, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786268, Length=292, Percent_Identity=22.9452054794521, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36705; Mature: 36574

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIKQIAKTAGVSISTVSRVLNNHPYVKEEKRKRVLDAVEELNYAKNINAIHLIKGKTY
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEE
TIGVMLPFINLPYFSTIIEGIGNEALAAGYHINLCQTNYDSIEEIRVLEMMKMKQFDGMI
EEEEEECHHCCHHHHHHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEE
ICSRTSSWEQIEPFAKFAPIISCEKMNHPLISSVYVDHYEGFRLGTAYLLKKGHEKIGIC
EEECCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEE
LARKTSANSMEREKAFADTLRKEGKTLHPEWIFHQCYTMQDGAQLLHRIVNMKNRPTAIF
EEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEE
TANDQVAAGLVTEARKQGLRVPEDLAILGFDNHEISKALEISTIEHPGLAMGSHAFSLFH
ECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHEEEECCCCCCHHHHHHHHHHH
KQMQSEQIIGNAKELSFHLIERDTV
HHHHHHHHHCCHHHHEEEEEECCCC
>Mature Secondary Structure 
ANIKQIAKTAGVSISTVSRVLNNHPYVKEEKRKRVLDAVEELNYAKNINAIHLIKGKTY
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEE
TIGVMLPFINLPYFSTIIEGIGNEALAAGYHINLCQTNYDSIEEIRVLEMMKMKQFDGMI
EEEEEECHHCCHHHHHHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEE
ICSRTSSWEQIEPFAKFAPIISCEKMNHPLISSVYVDHYEGFRLGTAYLLKKGHEKIGIC
EEECCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEE
LARKTSANSMEREKAFADTLRKEGKTLHPEWIFHQCYTMQDGAQLLHRIVNMKNRPTAIF
EEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEE
TANDQVAAGLVTEARKQGLRVPEDLAILGFDNHEISKALEISTIEHPGLAMGSHAFSLFH
ECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHEEEECCCCCCHHHHHHHHHHH
KQMQSEQIIGNAKELSFHLIERDTV
HHHHHHHHHCCHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]