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The map label for this gene is sipS2 [H]

Identifier: 218904968

GI number: 218904968

Start: 3690384

End: 3690935

Strand: Reverse

Name: sipS2 [H]

Synonym: BCAH820_3852

Alternate gene names: 218904968

Gene position: 3690935-3690384 (Counterclockwise)

Preceding gene: 218904969

Following gene: 218904967

Centisome position: 69.61

GC content: 35.33

Gene sequence:

>552_bases
ATGAAGAAAGAAAAGAGTTCACTTTGGGAATGGATCAAGGCAATTTTGATAGCTGTTGTATTAGCAGGTGTTATTAGACA
GTTTTTCTTTGCACCAATTCTCGTAGATGGAGTATCGATGGCATCTACTTTACATGATCGCGATCGAATGATTGTTAATA
AAATTGGTTATCACATAGGAGATCCGAAACGATTTGATATTATTGTATTCCGAGCAACGGAAGATAAAGATTATATTAAG
CGTATTATCGGCCTACCAGGCGATGAAATAGAGTATCATAATGATAAACTATATGTTAACGGAAAGGCTTATGAGGAGCC
GTATTTAGACAAGCAGAAGAAACAAATTGCTGACGGACCGCTTACATATGATTTTACTCTTGAAGAAATGACAGGGAAGA
AAACTGTTCCAGAAGGTCAATTATTTGTTTTAGGCGATAATCGTCGTTTTAGTAAAGATAGCCGTTCAATTGGTACAATT
TCAATGGACCAAGTGATTGGAAAAGCAAATATACTATATTGGCCATTAAAAGATGCTCGTATTGTGAAATAA

Upstream 100 bases:

>100_bases
ACATGTATGGGAGCTTGTAAATGCACAAGCTCCCTTTTTCCAATCTATATAAAATTTTGATATAATACGAGCAGCTTACA
TAATCGTGGAGGGGAAAAGC

Downstream 100 bases:

>100_bases
AAGAAAAAGAAGGTGGCAACATGGTAATTCAATGGTTCCCGGGACATATGGCAAAGGCTAGACGCCAAGTAACAGAAAAA
TTAAAGTTAATTGATGTTGT

Product: signal peptidase I S

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMASTLHDRDRMIVNKIGYHIGDPKRFDIIVFRATEDKDYIK
RIIGLPGDEIEYHNDKLYVNGKAYEEPYLDKQKKQIADGPLTYDFTLEEMTGKKTVPEGQLFVLGDNRRFSKDSRSIGTI
SMDQVIGKANILYWPLKDARIVK

Sequences:

>Translated_183_residues
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMASTLHDRDRMIVNKIGYHIGDPKRFDIIVFRATEDKDYIK
RIIGLPGDEIEYHNDKLYVNGKAYEEPYLDKQKKQIADGPLTYDFTLEEMTGKKTVPEGQLFVLGDNRRFSKDSRSIGTI
SMDQVIGKANILYWPLKDARIVK
>Mature_183_residues
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMASTLHDRDRMIVNKIGYHIGDPKRFDIIVFRATEDKDYIK
RIIGLPGDEIEYHNDKLYVNGKAYEEPYLDKQKKQIADGPLTYDFTLEEMTGKKTVPEGQLFVLGDNRRFSKDSRSIGTI
SMDQVIGKANILYWPLKDARIVK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21042; Mature: 21042

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMASTLHDRDRMIVNKIGYHIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPKRFDIIVFRATEDKDYIKRIIGLPGDEIEYHNDKLYVNGKAYEEPYLDKQKKQIADGP
CCCEEEEEEEEECCCHHHHHHHHCCCCCCEEEECCEEEECCCCCCCCCCCHHHHHHCCCC
LTYDFTLEEMTGKKTVPEGQLFVLGDNRRFSKDSRSIGTISMDQVIGKANILYWPLKDAR
EEEEEEHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCCEEEEECCCCE
IVK
ECC
>Mature Secondary Structure
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMASTLHDRDRMIVNKIGYHIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPKRFDIIVFRATEDKDYIKRIIGLPGDEIEYHNDKLYVNGKAYEEPYLDKQKKQIADGP
CCCEEEEEEEEECCCHHHHHHHHCCCCCCEEEECCEEEECCCCCCCCCCCHHHHHHCCCC
LTYDFTLEEMTGKKTVPEGQLFVLGDNRRFSKDSRSIGTISMDQVIGKANILYWPLKDAR
EEEEEEHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCCEEEEECCCCE
IVK
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]