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The map label for this gene is mecA2

Identifier: 218902701

GI number: 218902701

Start: 1497443

End: 1498051

Strand: Direct

Name: mecA2

Synonym: BCAH820_1584

Alternate gene names: 218902701

Gene position: 1497443-1498051 (Clockwise)

Preceding gene: 218902700

Following gene: 218902702

Centisome position: 28.24

GC content: 35.8

Gene sequence:

>609_bases
ATGAGGCTGGAACGATTAAATTACAATAAGATAAAAATTTTCTTAACATTTGATGATTTATCTGAACGAGGATTAACGAA
AGAAGATTTGTGGAGAAATGCACCGAAAGTACAGCAATTATTTCGTGATATGATGCAAGAAGCAAATAAAGAATTGGGAT
TTGAAGCGGATGGCCCGATTGCAGTTGAAGTATTTTCTCTACAAGCGCAAGGAATGGTCGTAATTGTAACGAAAGAACAT
CAAGAAGCGGATACAGATGATGAGTTCCGTGACGAGTTTATTGAAATGCAAGTGACTCTAGATGAAAGCGAGCATATCCT
TTATGAGTTTGCTACACTAGATGACGTAATTAACCTGTCGAATCGTTTATATAACCTTGATGTAACTGGCGGAAAATTAT
ATACGTGGGATGGGCGTTTCTATCTTTGGATGGAAGAAGAGGAGCAAATACAATTACTGAAGGCAGATTTTATAGCTATT
TTAGCGGAATATGGTAATCCGTCTACAGCAACTATTTATCGTCTAATGGAGTATGGTAAAGAATTAATGGCTTCTCAAGC
AATTGAACAAATACACAATTACTTTGTGAAAAAACAAAACCTTAGCTAA

Upstream 100 bases:

>100_bases
ATTGGTTAAAAATGTTAGAATAGTTGTTCGAAAAGAACCATCTATTTTCTATTTCATATAATAAAAATTATATTCATTGG
TTGCGTAGGGAGGGTATGAG

Downstream 100 bases:

>100_bases
TGTAACATAGCTAAGGTTTTGTTTTTTATTTTACTTAAATGTATCTTTTTAAAGTGCTGTATTTAAGTGAAATAAAAAAT
ATTTAAATATTTAAGTATTT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEH
QEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAI
LAEYGNPSTATIYRLMEYGKELMASQAIEQIHNYFVKKQNLS

Sequences:

>Translated_202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEH
QEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAI
LAEYGNPSTATIYRLMEYGKELMASQAIEQIHNYFVKKQNLS
>Mature_202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEH
QEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAI
LAEYGNPSTATIYRLMEYGKELMASQAIEQIHNYFVKKQNLS

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MECA2_BACAN (Q81SY4)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_843961.1
- RefSeq:   YP_018134.1
- RefSeq:   YP_027669.1
- EnsemblBacteria:   EBBACT00000011906
- EnsemblBacteria:   EBBACT00000016944
- EnsemblBacteria:   EBBACT00000021887
- GeneID:   1086207
- GeneID:   2817177
- GeneID:   2851805
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_1510
- KEGG:   bar:GBAA_1510
- KEGG:   bat:BAS1400
- TIGR:   BA_1510
- TIGR:   GBAA_1510
- GeneTree:   EBGT00050000001420
- HOGENOM:   HBG491202
- OMA:   DYIEMQV
- ProtClustDB:   PRK02899
- BioCyc:   BANT260799:BAS1400-MONOMER
- BioCyc:   BANT261594:GBAA1510-MONOMER
- HAMAP:   MF_01124
- InterPro:   IPR008681
- PIRSF:   PIRSF029008

Pfam domain/function: PF05389 MecA

EC number: NA

Molecular weight: Translated: 23730; Mature: 23730

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPI
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKEHQEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLS
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHEEEEEEECCCCEEEEHHHHHHHHHHHH
NRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAILAEYGNPSTATIYRLMEYGK
HHEEEEEECCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ELMASQAIEQIHNYFVKKQNLS
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPI
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKEHQEADTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLS
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHEEEEEEECCCCEEEEHHHHHHHHHHHH
NRLYNLDVTGGKLYTWDGRFYLWMEEEEQIQLLKADFIAILAEYGNPSTATIYRLMEYGK
HHEEEEEECCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ELMASQAIEQIHNYFVKKQNLS
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629