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The map label for this gene is resD [H]

Identifier: 218902686

GI number: 218902686

Start: 1485587

End: 1486339

Strand: Direct

Name: resD [H]

Synonym: BCAH820_1569

Alternate gene names: 218902686

Gene position: 1485587-1486339 (Clockwise)

Preceding gene: 218902685

Following gene: 218902687

Centisome position: 28.02

GC content: 37.72

Gene sequence:

>753_bases
GTGAACCGTTGTGGTAAAAGTACGCAACGGGTAGAAATGGAAAATGAATCAAGAATTTTAATTGTAGACGATGAGGATCG
TATTCGTCGTTTGTTGAAAATGTATTTAGAAAGAGAACAATACACAATTGAAGAAGCAGACAATGGTGATACAGCTTTAG
AAATGGCGTTGCAAAATGATTATGATTTAATCCTATTAGATCTTATGATGCCTGGTAAAGATGGTATTGAAGTATGTAAA
GGGGTTCGTGAGAAGAAAGCAACGCCAATTATTATGTTGACAGCAAAAGGTGAAGAAGTAAATCGAGTACAAGGGTTTGA
GGTAGGAACTGATGATTATATTGTGAAACCATTTAGCCCACGTGAAGTAGTGCTTCGAGTGAAAGCGGTCTTACGCCGTT
CTGTACCAACAACATTCTTTACACAAGATACAACGACAAAAGATGTTACTGTGTTCCCTCATTTAACAATTGATAATGAT
GCACACCGTGTTACAGCAGATGGGAATGAAGTGAATTTAACACCGAAAGAGTACGAATTACTATTATTCTTAGCGAAAGC
GCCTGATAAGGTATTTGATCGTGAGCAATTGTTAAAAGAAGTATGGCAATATGAATTCTTCGGAGATTTACGTACAGTTG
ATACGCATGTAAAGCGTTTACGTGAGAAGTTAAGCAAAAAATCACCAGATGCTGCGAAGATGATTGTTACCGTTTGGGGC
GTAGGTTACAAATTTGAGGTTGTGAACGACTGA

Upstream 100 bases:

>100_bases
ACTTTATTATTCTTGTGAAGCATAGTATGGAAAGTGAAACATTTAGAGGATTGCTTAAATAAACGAGAATAGCGCAACAT
AATAGTATAGAAGGGTAGGT

Downstream 100 bases:

>100_bases
TGCTTTGGAGAAGTGTAGTAGGGAAGTTATGGATGACCATATTACTTCTCGTTTCGTTCGTGCTTGGATTTGTTGCGATT
TTACTTTCACAGTTTTTTAG

Product: DNA-binding response regulator ResD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNRCGKSTQRVEMENESRILIVDDEDRIRRLLKMYLEREQYTIEEADNGDTALEMALQNDYDLILLDLMMPGKDGIEVCK
GVREKKATPIIMLTAKGEEVNRVQGFEVGTDDYIVKPFSPREVVLRVKAVLRRSVPTTFFTQDTTTKDVTVFPHLTIDND
AHRVTADGNEVNLTPKEYELLLFLAKAPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPDAAKMIVTVWG
VGYKFEVVND

Sequences:

>Translated_250_residues
MNRCGKSTQRVEMENESRILIVDDEDRIRRLLKMYLEREQYTIEEADNGDTALEMALQNDYDLILLDLMMPGKDGIEVCK
GVREKKATPIIMLTAKGEEVNRVQGFEVGTDDYIVKPFSPREVVLRVKAVLRRSVPTTFFTQDTTTKDVTVFPHLTIDND
AHRVTADGNEVNLTPKEYELLLFLAKAPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPDAAKMIVTVWG
VGYKFEVVND
>Mature_250_residues
MNRCGKSTQRVEMENESRILIVDDEDRIRRLLKMYLEREQYTIEEADNGDTALEMALQNDYDLILLDLMMPGKDGIEVCK
GVREKKATPIIMLTAKGEEVNRVQGFEVGTDDYIVKPFSPREVVLRVKAVLRRSVPTTFFTQDTTTKDVTVFPHLTIDND
AHRVTADGNEVNLTPKEYELLLFLAKAPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPDAAKMIVTVWG
VGYKFEVVND

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=44.4915254237288, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=41.5584415584416, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=34.1880341880342, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=35.4978354978355, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=36.3636363636364, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.0175438596491, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=35.8974358974359, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.9344978165939, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=34.070796460177, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=36.5638766519824, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=33.7662337662338, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=30.5676855895196, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=28.82096069869, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=26.4069264069264, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789149, Length=189, Percent_Identity=30.1587301587302, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=32.1100917431193, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=31.5315315315315, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=33.6206896551724, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28865; Mature: 28865

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRCGKSTQRVEMENESRILIVDDEDRIRRLLKMYLEREQYTIEEADNGDTALEMALQND
CCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCC
YDLILLDLMMPGKDGIEVCKGVREKKATPIIMLTAKGEEVNRVQGFEVGTDDYIVKPFSP
CCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHEECEEECCCCEEECCCCH
REVVLRVKAVLRRSVPTTFFTQDTTTKDVTVFPHLTIDNDAHRVTADGNEVNLTPKEYEL
HHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEECCCCCEEEECCCEEECCCCCEEE
LLFLAKAPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPDAAKMIVTVWG
EEEEECCCHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEC
VGYKFEVVND
CCEEEEEECC
>Mature Secondary Structure
MNRCGKSTQRVEMENESRILIVDDEDRIRRLLKMYLEREQYTIEEADNGDTALEMALQND
CCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCC
YDLILLDLMMPGKDGIEVCKGVREKKATPIIMLTAKGEEVNRVQGFEVGTDDYIVKPFSP
CCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHEECEEECCCCEEECCCCH
REVVLRVKAVLRRSVPTTFFTQDTTTKDVTVFPHLTIDNDAHRVTADGNEVNLTPKEYEL
HHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEECCCCCEEEECCCEEECCCCCEEE
LLFLAKAPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPDAAKMIVTVWG
EEEEECCCHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEC
VGYKFEVVND
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]