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The map label for this gene is resA [H]

Identifier: 218902683

GI number: 218902683

Start: 1481880

End: 1482401

Strand: Direct

Name: resA [H]

Synonym: BCAH820_1566

Alternate gene names: 218902683

Gene position: 1481880-1482401 (Clockwise)

Preceding gene: 218902682

Following gene: 218902684

Centisome position: 27.95

GC content: 33.91

Gene sequence:

>522_bases
ATGAAGAAAAATCGCTTATTATTTCGCGTTATCATTCTGCTCATTTTAAGCGGTGCTGTAGGATTTACACTTTATCAAGG
ATTCTTTGCTGATAAAGAGAAAATGCAAATTGGAAAAGAAGCGCCTAACTTTGTTGTGACGGATTTAGAAGGAAAGAAAA
TTGAACTAAAAGATTTAAAGGGAAAAGGTGTATTTTTAAATTTTTGGGGTACGTGGTGTAAACCTTGTGAGAAAGAAATG
CCTTATATGAATGAACTATACCCAAAGTATAAAGAAAAAGGCGTTGAAATTATTGCGTTAGATGCAGATGAGACGGACAT
CGCAGTAAAGAATTTTGTGAACCAATACGGTTTGAAATTCCCAGTTGCCATTGATAAAGGACAAAAAATTATAGGAACAT
ACGGAGTAGGACCATTACCATCAAGCTTCTTGATTGATAAAGATGGAAAAGTAGTGGAGCAAATTATAGGTGAACAAACG
AAAGAACAGTTAGAAGGATATTTAAAGAAAATTACTCCGTAA

Upstream 100 bases:

>100_bases
CGCTAATCGATATTGTGAAACTTTCACCAGTGGAATGTTCCGCTGGTGATTTATTAAAAAATACATATATTCATCACTCG
TCGAAGAGAGGGGAAACAAT

Downstream 100 bases:

>100_bases
TAAAGAAAGCCTTTACATAAGAGGTGCGTGTCTATAGTGCCTCTGGTTTAAAAATTCTGAGTATTGCGGTAACTTGAGGT
TAGAATATACAATAGTACAT

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPSSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP

Sequences:

>Translated_173_residues
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPSSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP
>Mature_173_residues
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPSSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=179, Percent_Identity=26.8156424581006, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19573; Mature: 19573

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLK
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEEECC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGQKIIGTYGVGPLPSSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
EEEECCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLK
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEEECC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGQKIIGTYGVGPLPSSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
EEEECCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA