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The map label for this gene is rsbP [H]

Identifier: 218902188

GI number: 218902188

Start: 1028684

End: 1029760

Strand: Direct

Name: rsbP [H]

Synonym: BCAH820_1070

Alternate gene names: 218902188

Gene position: 1028684-1029760 (Clockwise)

Preceding gene: 218902187

Following gene: 218902192

Centisome position: 19.4

GC content: 32.68

Gene sequence:

>1077_bases
GTGTCCATTTTAATTGTAGATGATAATCCGGTTAACATCTTTGTAATTGAAAAGATTTTAAAACAAGCCGGATATCAGGA
TCTTGTATCGCTGAATTCTGCACAAGAGCTTTTCGAATACATACAGTTTGGAAAAGATTCTTCCAGGCATAATGAAATTG
ATTTAATACTATTAGATATTATGATGCCTGAAATTGATGGACTTGAAGTTTGTAGGCGATTACAAAAAGAGGAGAAGTTT
AAAGATATTCCTATTATTTTTGTTACAGCTTTAGAAGATGCAAATAAATTAGCTGAAGCTCTTGATATGGGGGCAATGGA
TTATATTACGAAACCTATAAATAAAGTTGAGTTGTTAGCGCGTATGCGTGTAGCATTACGCTTGAAATCGGAATTAAATT
GGCATAAAGAACAGGAAGAAAATCTTCGGAATGAACTGGATTTAGCTACGCAAGTACAAAGAAACTTATTAAGTAGCCCA
TTAAGAGAAGAGCATATAAAAATTGAAGCAAGTTACTTACCTTCATTTAAACTAGCTGGAGATATGTATTACTGGTATAA
AATCGATGAAAACCGCTACGGTATTATATTATTAGATGTGATGGGACATGGTGTATCTGCTTCCTTAGTTTGCATGTTCA
TTTCGTCTGTATTACGTGAAACGATTAAATGTTTAATCGATCCAGAACTTGTCATGAAAGATTTAAATAAATATATGACT
CTTTTACATAATGAGAATGACAATATTCCATATTATTTTACAGCGATATACTTAGTAGTTAATACAGAAGATAGAACGAT
TGAATATGTAAATGCAGGACATCCTTCTGGATATGTTTTAGTTGATGAAACAAATGTAGTGGAACTAAATCGCGGGAGTT
GTGCGGTAGGATTTTTTGATGAAATAAAAGTTGAAAAGACAGTTATACCTTTTGAGAAGAACGCTCAAATCGTATTGTTT
ACAGATGGTGTACTTGAAGCAATAGCAAATGATGAATTTGAGGCTGAAGAGAAATTACGTACTTTTACAGAAAGAAAATG
GGGGAGAGTTAGAAGAAGAGATAGAAGGGTTTTATAA

Upstream 100 bases:

>100_bases
ATGAGTAGGAAATTTTCATTTTATAACTGAGTATGTAATACTAGAAAAATAGAAAATGATAACAGATTTACATTTTAAAT
AAGAAAAGGGGAAATCACTT

Downstream 100 bases:

>100_bases
GGAAGAACAGAAGGAAGCACAATCAGATGATATGTGTCTCATTATGATACAAATGAATGCGAAATAAAAAGCGTATGAAA
TCCAAATAGAGGATTTCATA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGKDSSRHNEIDLILLDIMMPEIDGLEVCRRLQKEEKF
KDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLARMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSP
LREEHIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFDEIKVEKTVIPFEKNAQIVLF
TDGVLEAIANDEFEAEEKLRTFTERKWGRVRRRDRRVL

Sequences:

>Translated_358_residues
MSILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGKDSSRHNEIDLILLDIMMPEIDGLEVCRRLQKEEKF
KDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLARMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSP
LREEHIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFDEIKVEKTVIPFEKNAQIVLF
TDGVLEAIANDEFEAEEKLRTFTERKWGRVRRRDRRVL
>Mature_357_residues
SILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGKDSSRHNEIDLILLDIMMPEIDGLEVCRRLQKEEKFK
DIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLARMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSPL
REEHIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMTL
LHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFDEIKVEKTVIPFEKNAQIVLFT
DGVLEAIANDEFEAEEKLRTFTERKWGRVRRRDRRVL

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=139, Percent_Identity=36.6906474820144, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788394, Length=126, Percent_Identity=37.3015873015873, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082012, Length=136, Percent_Identity=33.0882352941176, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786784, Length=127, Percent_Identity=33.8582677165354, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786599, Length=132, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786911, Length=130, Percent_Identity=36.9230769230769, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=113, Percent_Identity=32.7433628318584, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787229, Length=121, Percent_Identity=35.5371900826446, Blast_Score=61, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322044, Length=116, Percent_Identity=29.3103448275862, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 41482; Mature: 41351

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGKDSSRHNEIDLILLDI
CEEEEECCCCCEEHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEEE
MMPEIDGLEVCRRLQKEEKFKDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLA
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
RMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSPLREEHIKIEASYLPSFKLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCEEEEC
DMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
CEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFD
HHCCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEECCCCEEEECHH
EIKVEKTVIPFEKNAQIVLFTDGVLEAIANDEFEAEEKLRTFTERKWGRVRRRDRRVL
HHEEEEEEECCCCCCEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGKDSSRHNEIDLILLDI
EEEEECCCCCEEHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEEE
MMPEIDGLEVCRRLQKEEKFKDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLA
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
RMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSPLREEHIKIEASYLPSFKLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCEEEEC
DMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
CEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFD
HHCCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEECCCCEEEECHH
EIKVEKTVIPFEKNAQIVLFTDGVLEAIANDEFEAEEKLRTFTERKWGRVRRRDRRVL
HHEEEEEEECCCCCCEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]