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The map label for this gene is bkdR [H]

Identifier: 218902043

GI number: 218902043

Start: 880863

End: 881336

Strand: Direct

Name: bkdR [H]

Synonym: BCAH820_0925

Alternate gene names: 218902043

Gene position: 880863-881336 (Clockwise)

Preceding gene: 218902041

Following gene: 218902044

Centisome position: 16.61

GC content: 35.44

Gene sequence:

>474_bases
GTGTTAGATGATTTAGATGTACAAATTTTAGATATATTGCAGAAGGAATCACAAGTAAGTAATGCAGAGCTTGCGCGACG
TGTTAATTTATCACCAGCTGCAATGCATGCAAGAATTAAACGGTTAGATGGAGAAGGGTTCATTGATAAGCAAGTAGCTA
TTTTAAATCAAGAAAAGCTTGGTTTTGACTTGTTATGCTTCATTTTTATGAGTACGAATATTCATCAATCGGATAAACTT
GAAGTGTTGGAAAAAGAATTAGAAGCGATGCCGGAAGTGTTAGAATGTCACTGTTTAACAGGGGAGTATGATTATTTATT
AAAGGTTGCAAATCGTGATCGTAAAGAGCTGGAACAGTTTATTAGAAAGCTAAATAAGCTTGGTATTACAAGGATACAGA
CGAGTTTAGCACTTCGTGAAATTAAATATTCGACGGTATTACCGATACGAAATGAGGAACCGAGCATCGATTAG

Upstream 100 bases:

>100_bases
TTAAAGAAATATATTCAATTTTATATAAGTTATAAGGTGTTTTTTCGAATAATCATCGGTAAGAAAAAGGGGGATTATAA
TGGAATAGTCTGTTATTAAA

Downstream 100 bases:

>100_bases
ATTGCTTGGTTTTTTGTTTGTATAAAGTGATTGACGAGAAGAAAAGAGAGATGTATTATTATATAAAATTATGTATTAAA
ATTCATTTTGAGTTATAAAT

Product: transcriptional regulator, AsnC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MLDDLDVQILDILQKESQVSNAELARRVNLSPAAMHARIKRLDGEGFIDKQVAILNQEKLGFDLLCFIFMSTNIHQSDKL
EVLEKELEAMPEVLECHCLTGEYDYLLKVANRDRKELEQFIRKLNKLGITRIQTSLALREIKYSTVLPIRNEEPSID

Sequences:

>Translated_157_residues
MLDDLDVQILDILQKESQVSNAELARRVNLSPAAMHARIKRLDGEGFIDKQVAILNQEKLGFDLLCFIFMSTNIHQSDKL
EVLEKELEAMPEVLECHCLTGEYDYLLKVANRDRKELEQFIRKLNKLGITRIQTSLALREIKYSTVLPIRNEEPSID
>Mature_157_residues
MLDDLDVQILDILQKESQVSNAELARRVNLSPAAMHARIKRLDGEGFIDKQVAILNQEKLGFDLLCFIFMSTNIHQSDKL
EVLEKELEAMPEVLECHCLTGEYDYLLKVANRDRKELEQFIRKLNKLGITRIQTSLALREIKYSTVLPIRNEEPSID

Specific function: Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=37.0860927152318, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787116, Length=154, Percent_Identity=35.7142857142857, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1790182, Length=134, Percent_Identity=30.5970149253731, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18112; Mature: 18112

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDLDVQILDILQKESQVSNAELARRVNLSPAAMHARIKRLDGEGFIDKQVAILNQEKL
CCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
GFDLLCFIFMSTNIHQSDKLEVLEKELEAMPEVLECHCLTGEYDYLLKVANRDRKELEQF
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
IRKLNKLGITRIQTSLALREIKYSTVLPIRNEEPSID
HHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLDDLDVQILDILQKESQVSNAELARRVNLSPAAMHARIKRLDGEGFIDKQVAILNQEKL
CCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
GFDLLCFIFMSTNIHQSDKLEVLEKELEAMPEVLECHCLTGEYDYLLKVANRDRKELEQF
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
IRKLNKLGITRIQTSLALREIKYSTVLPIRNEEPSID
HHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320210 [H]