BacMap

Definition	Bacillus cereus AH820, complete genome.
Accession	NC_011773
Length	5,302,683

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The map label for this gene is yjdA [H]

Identifier: 218901374

GI number: 218901374

Start: 173762

End: 174538

Strand: Direct

Name: yjdA [H]

Synonym: BCAH820_0193

Alternate gene names: 218901374

Gene position: 173762-174538 (Clockwise)

Preceding gene: 218901369

Following gene: 218901379

Centisome position: 3.28

GC content: 37.32

Gene sequence:

>777_bases
ATGATGAATCAATTAAAAGATAAAGTAGCAGTTGTTACAGGTGTAAGTCGTTTAGATGGTATAGGCGCAGCAATTTGTAA
AGAATTAGCTGAGGCTGGATACAATATATTTTTTACGTATTGGACAGAGTATGATAAAGAGATGCCTTGGGGCGTTGATC
AAAGTGAACAAATACAATTACAAGAAGAGTTACTAAAAAACGGTGTGAAAGTATCGAGTATGGAGTTAGATTTAACTCAG
AATGATGCACCGAAAGAGCTTATAAATAAAGTTACTGAACAACTAGGCTACCCTCATATATTAATTAATAATGCAGCGTA
TTCTACGAATAATGATTTCTCTAATTTGACTGCTGAAGAATTAGATAAGCACTACATGGTCAATATTCGTGCGACTACAT
TATTAAGTAGTCAATTTGCCCGAGGATTTGATAAGAAATCTGGTGGTAGAATTGTGAATATGACTTCGGGGCAATTTCAA
GGGCCTATGGTTGGAGAACTGGCGTATGCAACAACGAAGGGGGCTATTGATGCTCTTACTAGTTCGTTGTCAGCCGAGGT
AGCTCATTTAGGAATAACAGTGAATGCAATTAACCCAGGTCCAACTGATACAGGCTGGATGACTGAAGAGATAAAGCAAG
GATTAAAACCAATGTTTCCTTTTGGCAGAATTGGTGAGCCAAAGGATGCAGCAAGACTCATTAAGTTTTTAGTAAGTGAA
GAAGCAGAGTGGATTACGGGACAAGTTATTCATTCAGAAGGTGGATTTAAAAGATAA

Upstream 100 bases:

>100_bases
CATATTTGGCTTGTGCGTCCCCTTTGTAAGGATAGATACTTATGTGGGGAAATTCATATCTCGTATATAAAATATGCGTC
CTTTAAAATTGGAGGAGTAT

Downstream 100 bases:

>100_bases
GAAGAAGGTATCTCACCAGGGTGAGATACCTTCTTTTTTAATCTTTCTTCAACCTTCGTGCAATACCATTCCCTAAAGAC
TGTAATCCTTGAACGAGGAT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MMNQLKDKVAVVTGVSRLDGIGAAICKELAEAGYNIFFTYWTEYDKEMPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQ
NDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQ
GPMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKQGLKPMFPFGRIGEPKDAARLIKFLVSE
EAEWITGQVIHSEGGFKR

Sequences:

>Translated_258_residues
MMNQLKDKVAVVTGVSRLDGIGAAICKELAEAGYNIFFTYWTEYDKEMPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQ
NDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQ
GPMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKQGLKPMFPFGRIGEPKDAARLIKFLVSE
EAEWITGQVIHSEGGFKR
>Mature_258_residues
MMNQLKDKVAVVTGVSRLDGIGAAICKELAEAGYNIFFTYWTEYDKEMPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQ
NDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQ
GPMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKQGLKPMFPFGRIGEPKDAARLIKFLVSE
EAEWITGQVIHSEGGFKR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.1158301158301, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=27.1317829457364, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=26.2172284644195, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=25.7936507936508, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503301, Length=208, Percent_Identity=25.9615384615385, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=25.1908396946565, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI59889578, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=31.8897637795276, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.0395256916996, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082100, Length=270, Percent_Identity=31.1111111111111, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=29.277566539924, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI2367365, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=28.0769230769231, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=29.6875, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=27.1604938271605, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=219, Percent_Identity=26.027397260274, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=24.031007751938, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=28.4615384615385, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=29.7101449275362, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=28.9855072463768, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=29.6028880866426, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=28.6231884057971, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=28.9855072463768, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=276, Percent_Identity=28.9855072463768, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=27.7978339350181, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=27.8985507246377, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=27.1255060728745, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=268, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=27.3722627737226, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=277, Percent_Identity=26.7148014440433, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=278, Percent_Identity=28.7769784172662, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=27.5193798449612, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=24.7148288973384, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=27.6264591439689, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=277, Percent_Identity=27.0758122743682, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=283, Percent_Identity=27.5618374558304, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=194, Percent_Identity=27.319587628866, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=269, Percent_Identity=24.5353159851301, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=283, Percent_Identity=27.5618374558304, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643142, Length=262, Percent_Identity=30.5343511450382, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=28.3524904214559, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=30.5660377358491, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=28.5171102661597, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357041, Length=267, Percent_Identity=28.8389513108614, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=28.6259541984733, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644337, Length=217, Percent_Identity=29.4930875576037, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28415; Mature: 28415

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNQLKDKVAVVTGVSRLDGIGAAICKELAEAGYNIFFTYWTEYDKEMPWGVDQSEQIQL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHH
QEELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEE
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCHHH
LDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGELAYATTKGAIDALT
CCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SSLSAEVAHLGITVNAINPGPTDTGWMTEEIKQGLKPMFPFGRIGEPKDAARLIKFLVSE
HHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHC
EAEWITGQVIHSEGGFKR
CCCHHEEEEEECCCCCCC
>Mature Secondary Structure
MMNQLKDKVAVVTGVSRLDGIGAAICKELAEAGYNIFFTYWTEYDKEMPWGVDQSEQIQL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHH
QEELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEE
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCHHH
LDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGELAYATTKGAIDALT
CCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SSLSAEVAHLGITVNAINPGPTDTGWMTEEIKQGLKPMFPFGRIGEPKDAARLIKFLVSE
HHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHC
EAEWITGQVIHSEGGFKR
CCCHHEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]