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The map label for this gene is cdc6 [H]

Identifier: 218884738

GI number: 218884738

Start: 1323734

End: 1324978

Strand: Direct

Name: cdc6 [H]

Synonym: DKAM_1427

Alternate gene names: 218884738

Gene position: 1323734-1324978 (Clockwise)

Preceding gene: 218884737

Following gene: 218884739

Centisome position: 96.96

GC content: 43.45

Gene sequence:

>1245_bases
GTGGTGAAGTGGGATGCAAGAAAAATAATAGAGGACGAGTTAAACAAGCAATCAATCTTTAAGAATCGTGAAAGCCTTAT
GCCGGAATACATACCTGAAGCACTGCCACACCGCGAGAACGAGCTCAAATTATTAGCCTCCTACTTCAGGCATTTAATAG
CGAACCCGGGTTCCATGTCTCAGAGAGTACTCATAGTAGGTAGAGTTGGAACCGGTAAGACGACGTTAATGAGGACCTTT
GCCACTAATTTAACGAGCATAGCAAGGGAGAAGGGCTTATCATTCGATTATATTCATGTCAACTGCTATAGGAATAGGAG
CTTGTTCAGTATAGTGAGGGATATAGCCTTGCAACTAGGCCTCTCAGTACCACATAGGGGATTATCATCGAAGGAGATAA
TGGATGCTGTTATCTCGTTCCTGGATGAGGGCGATCGGTATACTTTAATAGTATTCGACGACTTTCACTACTTCGTGAAT
ATAGCTGGTAAGGAAGCGATATACTTTATTACAAGGGCATACGAAGCCTTCCATGAGTCAAAGCGGTTGAACATGGTCTT
CGTGTCAACCGATACAAATATAATAGGGGTCTTCGACCCTGTCACCGAGTCGTATCTGAATAGATATATTATAAAACTAC
AGCCATACACCTCCAGTCAGTTACTTGATATATTGAGGTATAGGGCTAGCCTGGCCTTCCATGAGGATGCATATGATGAG
AAATTACTGGAGCTTATCGCTGAATATGAAGGGGTAGACAGGAGCGGCGAGGGTAATGCACGCCACGCCTTGACAATACT
ACTTACAGCTGGAGATATAGCTGAGAAAGAAGGAGCTGGGAGAATCAGCATAGAGCACGTCAGGAAAGCTATAACGATCC
ATGATAGAAGCAAGGAAATAGAGAGGATTAACGATGTATTAAAATACAGCTCCCTTCACGAGCTATTATTACTACTAAGC
ATAATACGCCTCCTACGCAAGAAAAACGATAAAGAAGTGGAAATGGGGGAGGTCGAAGACGAATACAGGCTACTCTGCAA
TATACACGGAGAAATACCGCGCTCTCATACACAGCTATACGAGTACACCAGAAACCTAAGTAAGACCGGCGTCATCAACG
CTGTCACTAAGAACATGGGTAACCGTGGTCGAACAACCCTCATATCCATACCTTATGGACCACTAGAAGAACTAGAGAAA
TACATCACTGCACTAGTAACGAAGAAGAGTGAGATAGAGTACTAG

Upstream 100 bases:

>100_bases
CAGCAGATGAATGCCTATTTATCGAGGGGATCAATGATAGAGTCTACATAGGCCTAGGACACTGTAGAACACGCATCGCA
GTACGTGGGGGATGAGGTAG

Downstream 100 bases:

>100_bases
GTGGCTTGCCCAATAACCGGTGAGTAGAGTTCTTTTATGGATCAGTAAACCAATAACATCTATTAGTGATGTAAATGGCT
TGCGTGGAGAAACCAATTAT

Product: cell division control protein 6

Products: NA

Alternate protein names: CDC6 homolog 2 [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MVKWDARKIIEDELNKQSIFKNRESLMPEYIPEALPHRENELKLLASYFRHLIANPGSMSQRVLIVGRVGTGKTTLMRTF
ATNLTSIAREKGLSFDYIHVNCYRNRSLFSIVRDIALQLGLSVPHRGLSSKEIMDAVISFLDEGDRYTLIVFDDFHYFVN
IAGKEAIYFITRAYEAFHESKRLNMVFVSTDTNIIGVFDPVTESYLNRYIIKLQPYTSSQLLDILRYRASLAFHEDAYDE
KLLELIAEYEGVDRSGEGNARHALTILLTAGDIAEKEGAGRISIEHVRKAITIHDRSKEIERINDVLKYSSLHELLLLLS
IIRLLRKKNDKEVEMGEVEDEYRLLCNIHGEIPRSHTQLYEYTRNLSKTGVINAVTKNMGNRGRTTLISIPYGPLEELEK
YITALVTKKSEIEY

Sequences:

>Translated_414_residues
MVKWDARKIIEDELNKQSIFKNRESLMPEYIPEALPHRENELKLLASYFRHLIANPGSMSQRVLIVGRVGTGKTTLMRTF
ATNLTSIAREKGLSFDYIHVNCYRNRSLFSIVRDIALQLGLSVPHRGLSSKEIMDAVISFLDEGDRYTLIVFDDFHYFVN
IAGKEAIYFITRAYEAFHESKRLNMVFVSTDTNIIGVFDPVTESYLNRYIIKLQPYTSSQLLDILRYRASLAFHEDAYDE
KLLELIAEYEGVDRSGEGNARHALTILLTAGDIAEKEGAGRISIEHVRKAITIHDRSKEIERINDVLKYSSLHELLLLLS
IIRLLRKKNDKEVEMGEVEDEYRLLCNIHGEIPRSHTQLYEYTRNLSKTGVINAVTKNMGNRGRTTLISIPYGPLEELEK
YITALVTKKSEIEY
>Mature_414_residues
MVKWDARKIIEDELNKQSIFKNRESLMPEYIPEALPHRENELKLLASYFRHLIANPGSMSQRVLIVGRVGTGKTTLMRTF
ATNLTSIAREKGLSFDYIHVNCYRNRSLFSIVRDIALQLGLSVPHRGLSSKEIMDAVISFLDEGDRYTLIVFDDFHYFVN
IAGKEAIYFITRAYEAFHESKRLNMVFVSTDTNIIGVFDPVTESYLNRYIIKLQPYTSSQLLDILRYRASLAFHEDAYDE
KLLELIAEYEGVDRSGEGNARHALTILLTAGDIAEKEGAGRISIEHVRKAITIHDRSKEIERINDVLKYSSLHELLLLLS
IIRLLRKKNDKEVEMGEVEDEYRLLCNIHGEIPRSHTQLYEYTRNLSKTGVINAVTKNMGNRGRTTLISIPYGPLEELEK
YITALVTKKSEIEY

Specific function: Might be involved in the initiation of DNA replication. Binds both single-strand and double-strand DNA. Has a weak ATPase activity. Strongly inhibits the ATPase and DNA helicase activity of the MCM protein [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C [H]

EC number: NA

Molecular weight: Translated: 47602; Mature: 47602

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKWDARKIIEDELNKQSIFKNRESLMPEYIPEALPHRENELKLLASYFRHLIANPGSMS
CCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
QRVLIVGRVGTGKTTLMRTFATNLTSIAREKGLSFDYIHVNCYRNRSLFSIVRDIALQLG
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHC
LSVPHRGLSSKEIMDAVISFLDEGDRYTLIVFDDFHYFVNIAGKEAIYFITRAYEAFHES
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHHHHHHCC
KRLNMVFVSTDTNIIGVFDPVTESYLNRYIIKLQPYTSSQLLDILRYRASLAFHEDAYDE
CCEEEEEEECCCCEEEEECHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
KLLELIAEYEGVDRSGEGNARHALTILLTAGDIAEKEGAGRISIEHVRKAITIHDRSKEI
HHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHCCCCCCEEHHHHHHHHHHCCCHHHH
ERINDVLKYSSLHELLLLLSIIRLLRKKNDKEVEMGEVEDEYRLLCNIHGEIPRSHTQLY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCCHHHHHH
EYTRNLSKTGVINAVTKNMGNRGRTTLISIPYGPLEELEKYITALVTKKSEIEY
HHHHCCCCCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCHHCCCC
>Mature Secondary Structure
MVKWDARKIIEDELNKQSIFKNRESLMPEYIPEALPHRENELKLLASYFRHLIANPGSMS
CCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
QRVLIVGRVGTGKTTLMRTFATNLTSIAREKGLSFDYIHVNCYRNRSLFSIVRDIALQLG
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHC
LSVPHRGLSSKEIMDAVISFLDEGDRYTLIVFDDFHYFVNIAGKEAIYFITRAYEAFHES
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHHHHHHCC
KRLNMVFVSTDTNIIGVFDPVTESYLNRYIIKLQPYTSSQLLDILRYRASLAFHEDAYDE
CCEEEEEEECCCCEEEEECHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
KLLELIAEYEGVDRSGEGNARHALTILLTAGDIAEKEGAGRISIEHVRKAITIHDRSKEI
HHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHCCCCCCEEHHHHHHHHHHCCCHHHH
ERINDVLKYSSLHELLLLLSIIRLLRKKNDKEVEMGEVEDEYRLLCNIHGEIPRSHTQLY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCCHHHHHH
EYTRNLSKTGVINAVTKNMGNRGRTTLISIPYGPLEELEKYITALVTKKSEIEY
HHHHCCCCCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]