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The map label for this gene is infB [H]

Identifier: 218884660

GI number: 218884660

Start: 1255503

End: 1257332

Strand: Direct

Name: infB [H]

Synonym: DKAM_1349

Alternate gene names: 218884660

Gene position: 1255503-1257332 (Clockwise)

Preceding gene: 218884643

Following gene: 218884662

Centisome position: 91.96

GC content: 44.75

Gene sequence:

>1830_bases
ATGGTGTTGGAGTTGAGTAGTGATAAGAAAACCTGGATTAGACAACCCATAATAGTTGTACTGGGTCATGTGGATCATGG
AAAAACAACACTACTTGATAAGATCAGGGGTACAGCTGTAGCTAAGAAGGAGCCAGGCGAGATAACGCAGCATGTTGGAG
CTAGTGTAGTACCTGCAAGTGTCTTAAACAAGATTACTGAGCCTCTAAAGAAGTATTTTCCAAAGCTAGTCATAGAGATA
CCGGGCTTACTCTTCATTGACACACCCGGGCATGAATTATTTAGTAATCTTAGGAGAAGAGGGGGTAGTGTAGCCGATAT
GGCTATACTTGTCGTAGATGTGGTTGAAGGATTCCAGCCTCAAACCATAGAGGCATTGAACATATTGAAGGAGAAGAGGG
TGCCATTCATTGTTGCAGCTAATAAAATAGATAGGCTTGAGGGATGGAAAGCCTTTCCAGACACTCCATTCCTTGAAAGC
GTTAAGAGGCAAAGCCCTAGAACGATAAGTATTCTAGAGGAGAGGATATACCAGTTGGTCGGCAAGTTATACGAGTATGG
GTTTGAGTCGGAAAGATTTGACAGGGTCAAAGACTTCAGGAGAACAGTTGCAATAGTGCCGATATCGGCTAAAACAGGTG
AGGGAATATCAGAGTTGCTTGCACTTATAGCTGGCCTCGCACAGCAGTTCATGAAGAAGAAGCTTGTGACTAGTGAAGAC
GCTGCTAGAGGGGTAGTATTAGAGGTTAAAGAGGAGCAAGGCCTTGGCACCACTATAGATGTTATAATCTATGATGGAGT
GCTAAGCAAAAACGATCTCTTCGTAGTTGCTGGTAAGAATGGCCCAATAGTTACAAGGGTTAGGAGCCTATTGATGCCAA
GGCCCCTCCAAGATATGAGGATGCATGAGGGTCGATTCGTACAAGTAGACCTTGTCACAGCTGCTACAGGAGTGAAAATA
TCCGCCCCAGGACTCGAGGATGCATTAGCTGGCTCACCATTCTACGTAATACCCTCCGAGGATAGGATCCAGGAATTCAC
CAGGGCGGTTCAAGAGGAGGTATCTCAGATAAGGTTTAAAGGGGAAAGCGATGGCGTCGTATTAAAGGCGGATACTCTTG
GAACACTGGAAGCCCTCCTGGAGGCCCTTAGGCGTGAGAATATACCGGTTAAACTAGCAGATGTCGGCCATGTAACCAGG
AATGACGTCCTAGAAGCCGCCATTGTTAGTAAATCTAAACCTGAGTATGGTGTAATACTGGCTTTCAACGTGAAGATCCT
GCCTGAAGCAGAGGAGTTGAGGGCCCGGGAAAACATACCCGTGTTTAAACATAATATAATATACCAGCTACTCGAAGAAT
ACCTTAAATGGTTCAAGGAATTCAGGGAGAGGGAGAGACTGAGGCAGGTAGAGTCTCTAGTAAGGCCAGGTAAGATAAGG
ATTATACCGGGGGCTGTATTTAGGAGAAGTGAACCCGTTATAGTTGGAGTAGAAGTCCTGGGAGGCAGGATAAGGCCTAA
CTATCCATTAATGACAGAGGATGGGAGAAACATTGGCTTAATAATGCAGATACGCGACCGCGATAACGTGTTGAAGGAGG
CGCTTGTAGGGCAACAAGTAGCTATAAGTATTAGGGGCAAGGTAATGGTGGGTAGGCACATAGATGAAGGCGATATCTTG
TATACTGATATACCAAGTGAACACGTTAAATACTGGCTGACAACTTTTAGTAATGAGTTAAGCAATGATGAGAAACTAGT
GTTGAAAGAAATAATTGATATAAAGAGGAAGAGCGATCCCCTCTACGGTATGGTGTTTCAGCAGATGTGA

Upstream 100 bases:

>100_bases
CCCGCAACAGGCTGATGCCGTAAAATAAGAATTAACCGATATAAGCACGTTAATGGTTTAGAATAACTAGGCTTACTAGT
GGGCCACATACAGTGTTTAC

Downstream 100 bases:

>100_bases
AAACAAAATAACCTGGCCTACTTTGTCTGCTGACCATACTTTAATGTCCACTTATACTTCCTAGGATCCCTCTTCATCCT
GTAGTTATTAAAACACTTAT

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MVLELSSDKKTWIRQPIIVVLGHVDHGKTTLLDKIRGTAVAKKEPGEITQHVGASVVPASVLNKITEPLKKYFPKLVIEI
PGLLFIDTPGHELFSNLRRRGGSVADMAILVVDVVEGFQPQTIEALNILKEKRVPFIVAANKIDRLEGWKAFPDTPFLES
VKRQSPRTISILEERIYQLVGKLYEYGFESERFDRVKDFRRTVAIVPISAKTGEGISELLALIAGLAQQFMKKKLVTSED
AARGVVLEVKEEQGLGTTIDVIIYDGVLSKNDLFVVAGKNGPIVTRVRSLLMPRPLQDMRMHEGRFVQVDLVTAATGVKI
SAPGLEDALAGSPFYVIPSEDRIQEFTRAVQEEVSQIRFKGESDGVVLKADTLGTLEALLEALRRENIPVKLADVGHVTR
NDVLEAAIVSKSKPEYGVILAFNVKILPEAEELRARENIPVFKHNIIYQLLEEYLKWFKEFRERERLRQVESLVRPGKIR
IIPGAVFRRSEPVIVGVEVLGGRIRPNYPLMTEDGRNIGLIMQIRDRDNVLKEALVGQQVAISIRGKVMVGRHIDEGDIL
YTDIPSEHVKYWLTTFSNELSNDEKLVLKEIIDIKRKSDPLYGMVFQQM

Sequences:

>Translated_609_residues
MVLELSSDKKTWIRQPIIVVLGHVDHGKTTLLDKIRGTAVAKKEPGEITQHVGASVVPASVLNKITEPLKKYFPKLVIEI
PGLLFIDTPGHELFSNLRRRGGSVADMAILVVDVVEGFQPQTIEALNILKEKRVPFIVAANKIDRLEGWKAFPDTPFLES
VKRQSPRTISILEERIYQLVGKLYEYGFESERFDRVKDFRRTVAIVPISAKTGEGISELLALIAGLAQQFMKKKLVTSED
AARGVVLEVKEEQGLGTTIDVIIYDGVLSKNDLFVVAGKNGPIVTRVRSLLMPRPLQDMRMHEGRFVQVDLVTAATGVKI
SAPGLEDALAGSPFYVIPSEDRIQEFTRAVQEEVSQIRFKGESDGVVLKADTLGTLEALLEALRRENIPVKLADVGHVTR
NDVLEAAIVSKSKPEYGVILAFNVKILPEAEELRARENIPVFKHNIIYQLLEEYLKWFKEFRERERLRQVESLVRPGKIR
IIPGAVFRRSEPVIVGVEVLGGRIRPNYPLMTEDGRNIGLIMQIRDRDNVLKEALVGQQVAISIRGKVMVGRHIDEGDIL
YTDIPSEHVKYWLTTFSNELSNDEKLVLKEIIDIKRKSDPLYGMVFQQM
>Mature_609_residues
MVLELSSDKKTWIRQPIIVVLGHVDHGKTTLLDKIRGTAVAKKEPGEITQHVGASVVPASVLNKITEPLKKYFPKLVIEI
PGLLFIDTPGHELFSNLRRRGGSVADMAILVVDVVEGFQPQTIEALNILKEKRVPFIVAANKIDRLEGWKAFPDTPFLES
VKRQSPRTISILEERIYQLVGKLYEYGFESERFDRVKDFRRTVAIVPISAKTGEGISELLALIAGLAQQFMKKKLVTSED
AARGVVLEVKEEQGLGTTIDVIIYDGVLSKNDLFVVAGKNGPIVTRVRSLLMPRPLQDMRMHEGRFVQVDLVTAATGVKI
SAPGLEDALAGSPFYVIPSEDRIQEFTRAVQEEVSQIRFKGESDGVVLKADTLGTLEALLEALRRENIPVKLADVGHVTR
NDVLEAAIVSKSKPEYGVILAFNVKILPEAEELRARENIPVFKHNIIYQLLEEYLKWFKEFRERERLRQVESLVRPGKIR
IIPGAVFRRSEPVIVGVEVLGGRIRPNYPLMTEDGRNIGLIMQIRDRDNVLKEALVGQQVAISIRGKVMVGRHIDEGDIL
YTDIPSEHVKYWLTTFSNELSNDEKLVLKEIIDIKRKSDPLYGMVFQQM

Specific function: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 [H]

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family [H]

Homologues:

Organism=Homo sapiens, GI84043963, Length=596, Percent_Identity=38.5906040268456, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI53729339, Length=266, Percent_Identity=35.3383458646617, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI53729337, Length=266, Percent_Identity=35.3383458646617, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1789559, Length=475, Percent_Identity=29.2631578947368, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI212656558, Length=600, Percent_Identity=37.5, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71994658, Length=498, Percent_Identity=25.3012048192771, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319282, Length=601, Percent_Identity=37.1048252911814, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324550, Length=477, Percent_Identity=25.7861635220126, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24656849, Length=579, Percent_Identity=37.8238341968912, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28572034, Length=482, Percent_Identity=29.045643153527, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI160714833, Length=88, Percent_Identity=45.4545454545455, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR004544
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2 [H]

EC number: NA

Molecular weight: Translated: 68455; Mature: 68455

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLELSSDKKTWIRQPIIVVLGHVDHGKTTLLDKIRGTAVAKKEPGEITQHVGASVVPAS
CEEEECCCCHHHHHCCEEEEEECCCCCHHHHHHHHCCCEECCCCCCHHHHHCCCCCHHHH
VLNKITEPLKKYFPKLVIEIPGLLFIDTPGHELFSNLRRRGGSVADMAILVVDVVEGFQP
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
QTIEALNILKEKRVPFIVAANKIDRLEGWKAFPDTPFLESVKRQSPRTISILEERIYQLV
CHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
GKLYEYGFESERFDRVKDFRRTVAIVPISAKTGEGISELLALIAGLAQQFMKKKLVTSED
HHHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AARGVVLEVKEEQGLGTTIDVIIYDGVLSKNDLFVVAGKNGPIVTRVRSLLMPRPLQDMR
CCCCEEEEEECCCCCCCEEEEEEECCEECCCCEEEEECCCCCHHHHHHHHHCCCCHHHHH
MHEGRFVQVDLVTAATGVKISAPGLEDALAGSPFYVIPSEDRIQEFTRAVQEEVSQIRFK
HCCCCEEEEEEEEEECCCEEECCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHEEC
GESDGVVLKADTLGTLEALLEALRRENIPVKLADVGHVTRNDVLEAAIVSKSKPEYGVIL
CCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEEE
AFNVKILPEAEELRARENIPVFKHNIIYQLLEEYLKWFKEFRERERLRQVESLVRPGKIR
EEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IIPGAVFRRSEPVIVGVEVLGGRIRPNYPLMTEDGRNIGLIMQIRDRDNVLKEALVGQQV
EECHHHHCCCCCEEEEEEECCCCCCCCCCEECCCCCCEEEEEEECCHHHHHHHHHCCCEE
AISIRGKVMVGRHIDEGDILYTDIPSEHVKYWLTTFSNELSNDEKLVLKEIIDIKRKSDP
EEEEECEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LYGMVFQQM
HHHHHHHCC
>Mature Secondary Structure
MVLELSSDKKTWIRQPIIVVLGHVDHGKTTLLDKIRGTAVAKKEPGEITQHVGASVVPAS
CEEEECCCCHHHHHCCEEEEEECCCCCHHHHHHHHCCCEECCCCCCHHHHHCCCCCHHHH
VLNKITEPLKKYFPKLVIEIPGLLFIDTPGHELFSNLRRRGGSVADMAILVVDVVEGFQP
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
QTIEALNILKEKRVPFIVAANKIDRLEGWKAFPDTPFLESVKRQSPRTISILEERIYQLV
CHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
GKLYEYGFESERFDRVKDFRRTVAIVPISAKTGEGISELLALIAGLAQQFMKKKLVTSED
HHHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AARGVVLEVKEEQGLGTTIDVIIYDGVLSKNDLFVVAGKNGPIVTRVRSLLMPRPLQDMR
CCCCEEEEEECCCCCCCEEEEEEECCEECCCCEEEEECCCCCHHHHHHHHHCCCCHHHHH
MHEGRFVQVDLVTAATGVKISAPGLEDALAGSPFYVIPSEDRIQEFTRAVQEEVSQIRFK
HCCCCEEEEEEEEEECCCEEECCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHEEC
GESDGVVLKADTLGTLEALLEALRRENIPVKLADVGHVTRNDVLEAAIVSKSKPEYGVIL
CCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEEE
AFNVKILPEAEELRARENIPVFKHNIIYQLLEEYLKWFKEFRERERLRQVESLVRPGKIR
EEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IIPGAVFRRSEPVIVGVEVLGGRIRPNYPLMTEDGRNIGLIMQIRDRDNVLKEALVGQQV
EECHHHHCCCCCEEEEEEECCCCCCCCCCEECCCCCCEEEEEEECCHHHHHHHHHCCCEE
AISIRGKVMVGRHIDEGDILYTDIPSEHVKYWLTTFSNELSNDEKLVLKEIIDIKRKSDP
EEEEECEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LYGMVFQQM
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA