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The map label for this gene is atpA [H]

Identifier: 218884308

GI number: 218884308

Start: 942635

End: 944389

Strand: Direct

Name: atpA [H]

Synonym: DKAM_0997

Alternate gene names: 218884308

Gene position: 942635-944389 (Clockwise)

Preceding gene: 218884307

Following gene: 218884309

Centisome position: 69.05

GC content: 46.32

Gene sequence:

>1755_bases
ATGAGTATGCATAAAGGGATAATACATAGGGTTTCAGGCCCCCTTGTAGTAGCTGAAAACGTGCGAGGTGTAAGCATCTA
CGAGGTAATCGAGGTAGGTGAGGAGAGATTAATTGGTGAGGCCATAGGGGTAGAGGGCGATAAGGCGATAATACAGGTAT
ACGAGGATACCACAGGGTTAAAAGTTGGTGACCCCGTATACCCTACCGGGCAACCATTATCAGCTGAGCTAGGGCCAGGC
CTGATAAAATCCATATTCGATGGAATCCAGCGCCCTCTACCAGTCATCGAGGCACTTTCAGGCATATTCGTTAGGAAGGG
GGTCAGGACGACTCCTTTACCACGTGATAAAAAATGGCACTTCATCCCACTTGTCAAACCAGGTGATAAAGTTGTCGAGG
GTGACTTCATAGGTTACGTTAATGAAACAGAGGTGGTTAAACACTATATAATGGTTCCACCAGGAATTAACGGGGTTATT
GAATGGGTGGCCAGTGAAGGAGATTACAGTATAGTAGAGCCTATTGCCAAGATAAGCGGTAAAGAAGTATCAATGCTCCA
GAAATGGCCTGTTAGAAGACCTAGGCCTTACAAGGAGAAATTAGAGCCCAGAGAGCCGTTCATTACAGGTATTAGAGTTA
TAGATTTTCTATTCCCATTAGCTAAAGGCGGTAAAGCCGCTGTGCCGGGAGGCTTTGGCACAGGTAAAACAGTCCTGCTT
CACACCGTTACAAAGTGGAGTGAGGCAGATATAACGATTTACATCGGATGCGGCGAGAGAGGAAACGAGATGGCTGACGC
ATTAAACAGTTTCATCAAGCTAATAGATCCTAAGACCGGTAAAACAATGATGGAGAGAAGCATCTTCATAGCTAACACCA
GCAACATGCCTGTCGCAGCCAGGGAGGCAAGTATATTCCTAGGTATTACACTTGGAGAATACTATAGGGATATGGGCTAC
AACATCCTCCTCGTTGCAGACTCAACTAGCAGGTGGGCTGAGGCGATGAGAGAGATCAGTGGGCGTTTAGAGGAGCTACC
GGGTGAGGAAGGCTTCCCAGCCTATCTGGCATCAAGGCTGGCACAGTTCTACGAGAGAAGCGGGTACGTAAAAACCATTG
GCTCAGCTGAGAGAAGCGGCAGCCTCACCATCATGGGTGCAGTGTCACCGCCTGGAGCAGACTTCAGTGAACCAGTTACA
CAATCCACTCTAAGGCTTATCAGGGCATTATATGCATTAGACGTTAACCTAGCGTATAGAAGGCACTACCCATCAATAAA
CTGGCTAACCAGCTTCAGCCTATATATAGATAATGTAACAGAATGGTGGTCTAAAATAAGCCGTGAATACCCGTATCTAA
GGGAGAGGTTCATGAAGATCCTGCAGAGAGAGACCGAGCTAGAGGAATTAGTGAGGCTGGTGGGAGCCGACGCGCTACCT
GTGGAGGATCGGCTCACCCTTGAAGTAGCTAGGATTATACGAGAGGACTTCCTACAGCAAGATGCGTTTAGCCTCGTCGA
TGTCTTCTCCCACCCTGTTAAAACAGTTAAGATGGCTACAATAATAGATAAGTTCTACGAGAAAGCTCTCGAAGCAATAA
AGCTGGGAGTGTCATTCGAGAAAATACGCGGCATGAAGATAAGGGAGAGAATTGCTAGAATGAAGCATATACCTTTTGGA
GATAACACCAAGGAATTTGATAGTATACTTATAGAAATGGAGGAAGAATTCAAGAATCTTAGGGAGGAGAGTTAG

Upstream 100 bases:

>100_bases
AGATAGCTAAGAAATACCTGGGCATTGAAATACCTATATAATCTTTCCCGACTAATAGAAATACCTGTAAATATGTTTAC
TCTGGTAAAGGCGAATCGTC

Downstream 100 bases:

>100_bases
ATATGTCGGTGAAATTAACCACAAGGATCTCAAGTAAACTACTTAAAGCACAGGGAGGACTATTATTCGCTGAGACAATA
CCTGGTGTAACATATGGTGA

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSMHKGIIHRVSGPLVVAENVRGVSIYEVIEVGEERLIGEAIGVEGDKAIIQVYEDTTGLKVGDPVYPTGQPLSAELGPG
LIKSIFDGIQRPLPVIEALSGIFVRKGVRTTPLPRDKKWHFIPLVKPGDKVVEGDFIGYVNETEVVKHYIMVPPGINGVI
EWVASEGDYSIVEPIAKISGKEVSMLQKWPVRRPRPYKEKLEPREPFITGIRVIDFLFPLAKGGKAAVPGGFGTGKTVLL
HTVTKWSEADITIYIGCGERGNEMADALNSFIKLIDPKTGKTMMERSIFIANTSNMPVAAREASIFLGITLGEYYRDMGY
NILLVADSTSRWAEAMREISGRLEELPGEEGFPAYLASRLAQFYERSGYVKTIGSAERSGSLTIMGAVSPPGADFSEPVT
QSTLRLIRALYALDVNLAYRRHYPSINWLTSFSLYIDNVTEWWSKISREYPYLRERFMKILQRETELEELVRLVGADALP
VEDRLTLEVARIIREDFLQQDAFSLVDVFSHPVKTVKMATIIDKFYEKALEAIKLGVSFEKIRGMKIRERIARMKHIPFG
DNTKEFDSILIEMEEEFKNLREES

Sequences:

>Translated_584_residues
MSMHKGIIHRVSGPLVVAENVRGVSIYEVIEVGEERLIGEAIGVEGDKAIIQVYEDTTGLKVGDPVYPTGQPLSAELGPG
LIKSIFDGIQRPLPVIEALSGIFVRKGVRTTPLPRDKKWHFIPLVKPGDKVVEGDFIGYVNETEVVKHYIMVPPGINGVI
EWVASEGDYSIVEPIAKISGKEVSMLQKWPVRRPRPYKEKLEPREPFITGIRVIDFLFPLAKGGKAAVPGGFGTGKTVLL
HTVTKWSEADITIYIGCGERGNEMADALNSFIKLIDPKTGKTMMERSIFIANTSNMPVAAREASIFLGITLGEYYRDMGY
NILLVADSTSRWAEAMREISGRLEELPGEEGFPAYLASRLAQFYERSGYVKTIGSAERSGSLTIMGAVSPPGADFSEPVT
QSTLRLIRALYALDVNLAYRRHYPSINWLTSFSLYIDNVTEWWSKISREYPYLRERFMKILQRETELEELVRLVGADALP
VEDRLTLEVARIIREDFLQQDAFSLVDVFSHPVKTVKMATIIDKFYEKALEAIKLGVSFEKIRGMKIRERIARMKHIPFG
DNTKEFDSILIEMEEEFKNLREES
>Mature_583_residues
SMHKGIIHRVSGPLVVAENVRGVSIYEVIEVGEERLIGEAIGVEGDKAIIQVYEDTTGLKVGDPVYPTGQPLSAELGPGL
IKSIFDGIQRPLPVIEALSGIFVRKGVRTTPLPRDKKWHFIPLVKPGDKVVEGDFIGYVNETEVVKHYIMVPPGINGVIE
WVASEGDYSIVEPIAKISGKEVSMLQKWPVRRPRPYKEKLEPREPFITGIRVIDFLFPLAKGGKAAVPGGFGTGKTVLLH
TVTKWSEADITIYIGCGERGNEMADALNSFIKLIDPKTGKTMMERSIFIANTSNMPVAAREASIFLGITLGEYYRDMGYN
ILLVADSTSRWAEAMREISGRLEELPGEEGFPAYLASRLAQFYERSGYVKTIGSAERSGSLTIMGAVSPPGADFSEPVTQ
STLRLIRALYALDVNLAYRRHYPSINWLTSFSLYIDNVTEWWSKISREYPYLRERFMKILQRETELEELVRLVGADALPV
EDRLTLEVARIIREDFLQQDAFSLVDVFSHPVKTVKMATIIDKFYEKALEAIKLGVSFEKIRGMKIRERIARMKHIPFGD
NTKEFDSILIEMEEEFKNLREES

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=599, Percent_Identity=46.4106844741235, Blast_Score=553, Evalue=1e-157,
Organism=Homo sapiens, GI32189394, Length=351, Percent_Identity=30.1994301994302, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI19913426, Length=355, Percent_Identity=26.7605633802817, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI19913428, Length=325, Percent_Identity=25.8461538461538, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI50345984, Length=247, Percent_Identity=26.7206477732794, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI4757810, Length=247, Percent_Identity=26.7206477732794, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1790170, Length=349, Percent_Identity=29.512893982808, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1788251, Length=300, Percent_Identity=28.6666666666667, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790172, Length=245, Percent_Identity=26.1224489795918, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17565854, Length=599, Percent_Identity=47.4123539232053, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI25144756, Length=331, Percent_Identity=31.7220543806647, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17510931, Length=313, Percent_Identity=26.517571884984, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17570191, Length=321, Percent_Identity=25.5451713395639, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71988080, Length=247, Percent_Identity=25.9109311740891, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71988063, Length=247, Percent_Identity=25.9109311740891, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988074, Length=247, Percent_Identity=25.9109311740891, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320016, Length=337, Percent_Identity=44.5103857566766, Blast_Score=296, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6322581, Length=351, Percent_Identity=28.7749287749288, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319603, Length=332, Percent_Identity=25, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319370, Length=242, Percent_Identity=28.099173553719, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24583992, Length=598, Percent_Identity=47.6588628762542, Blast_Score=555, Evalue=1e-158,
Organism=Drosophila melanogaster, GI24583988, Length=599, Percent_Identity=47.5792988313856, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24583986, Length=599, Percent_Identity=47.5792988313856, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24583984, Length=599, Percent_Identity=47.5792988313856, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI20129479, Length=569, Percent_Identity=47.6274165202109, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI28574560, Length=329, Percent_Identity=30.3951367781155, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24638766, Length=333, Percent_Identity=31.5315315315315, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281361666, Length=324, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646341, Length=324, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136796, Length=324, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24658560, Length=247, Percent_Identity=27.5303643724696, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 65617; Mature: 65486

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMHKGIIHRVSGPLVVAENVRGVSIYEVIEVGEERLIGEAIGVEGDKAIIQVYEDTTGL
CCCCHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
KVGDPVYPTGQPLSAELGPGLIKSIFDGIQRPLPVIEALSGIFVRKGVRTTPLPRDKKWH
EECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
FIPLVKPGDKVVEGDFIGYVNETEVVKHYIMVPPGINGVIEWVASEGDYSIVEPIAKISG
EEEEECCCCCEECCCEEECCCHHHHHHHEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCC
KEVSMLQKWPVRRPRPYKEKLEPREPFITGIRVIDFLFPLAKGGKAAVPGGFGTGKTVLL
CHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
HTVTKWSEADITIYIGCGERGNEMADALNSFIKLIDPKTGKTMMERSIFIANTSNMPVAA
EEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCCCCEEE
REASIFLGITLGEYYRDMGYNILLVADSTSRWAEAMREISGRLEELPGEEGFPAYLASRL
ECCEEEEEEEHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AQFYERSGYVKTIGSAERSGSLTIMGAVSPPGADFSEPVTQSTLRLIRALYALDVNLAYR
HHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
RHYPSINWLTSFSLYIDNVTEWWSKISREYPYLRERFMKILQRETELEELVRLVGADALP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VEDRLTLEVARIIREDFLQQDAFSLVDVFSHPVKTVKMATIIDKFYEKALEAIKLGVSFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KIRGMKIRERIARMKHIPFGDNTKEFDSILIEMEEEFKNLREES
HHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SMHKGIIHRVSGPLVVAENVRGVSIYEVIEVGEERLIGEAIGVEGDKAIIQVYEDTTGL
CCCHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
KVGDPVYPTGQPLSAELGPGLIKSIFDGIQRPLPVIEALSGIFVRKGVRTTPLPRDKKWH
EECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
FIPLVKPGDKVVEGDFIGYVNETEVVKHYIMVPPGINGVIEWVASEGDYSIVEPIAKISG
EEEEECCCCCEECCCEEECCCHHHHHHHEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCC
KEVSMLQKWPVRRPRPYKEKLEPREPFITGIRVIDFLFPLAKGGKAAVPGGFGTGKTVLL
CHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
HTVTKWSEADITIYIGCGERGNEMADALNSFIKLIDPKTGKTMMERSIFIANTSNMPVAA
EEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCCCCEEE
REASIFLGITLGEYYRDMGYNILLVADSTSRWAEAMREISGRLEELPGEEGFPAYLASRL
ECCEEEEEEEHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AQFYERSGYVKTIGSAERSGSLTIMGAVSPPGADFSEPVTQSTLRLIRALYALDVNLAYR
HHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
RHYPSINWLTSFSLYIDNVTEWWSKISREYPYLRERFMKILQRETELEELVRLVGADALP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VEDRLTLEVARIIREDFLQQDAFSLVDVFSHPVKTVKMATIIDKFYEKALEAIKLGVSFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KIRGMKIRERIARMKHIPFGDNTKEFDSILIEMEEEFKNLREES
HHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA