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The map label for this gene is atpI [H]

Identifier: 218884303

GI number: 218884303

Start: 938182

End: 940155

Strand: Direct

Name: atpI [H]

Synonym: DKAM_0992

Alternate gene names: 218884303

Gene position: 938182-940155 (Clockwise)

Preceding gene: 218884302

Following gene: 218884304

Centisome position: 68.72

GC content: 42.25

Gene sequence:

>1974_bases
ATGGGACTCTTATTAAGCAAACCCAGTGAAATGGTAAAAATAAATGCGGCCTTCCTCCAAGCTGATAAAGAGAAGGCGCT
ACGTTTACTACAGGAGGCCGGGGTTATCGATATAGAACCAGTTGAAGCAGAGAAGATAGTGAGAGAATATGAAAGACTAC
AGTCTCTTAGAGAACGTATTAACTCACTGATCCAGAAAGCTAAGGGCCTAGCTATAAATGTATCTATAACAGGCCTGGAG
CTATCATCGATCGAGATAAGCCGGATAGAGAAGGATGTAGCTAGCCTGCAAGACGAAGTGGCATTACTAGAGGGTAAATT
GAAACATGTGAGGGAGACACTTGACTCCCTTAAAATGCTTCAGACAGCCATAAACCCTCTACCAGACACCATGGAGACCA
CTGAGATATATTATGAGGGTAGGCATCTCTCATCAATCCTTTTAACAGGTAAGCGGGAAACAATCAATGAACTAGTAGAA
AAACCCGGCTTGATTAAAGCTGCACACTCGTTTAAGATCGATGAGGAGCAAGTATCCATTATAGTATATGTTTCATCACA
GGATTTAAACCAGCTGCTCTCACTAGCATCCTCTATGGGGATATGGTATCCCGGTAGACAACTACTAGAGTTCATACAGC
CACATAAATCAATCGGCTTACTTAAAGAGTATCTTGGAAAGAAGATAACCGAGCTAAGCGAGGAGGATGAAAGCCTAGAA
GGGAAAATCGTTGAAAAGATCAAGTCTCATGGAGAAATCCTGGGTAAGTATCTCTTAATCGTGGAGAACTATATTGAATA
TTATAAGGTAAGCGGGATAACGACTGATCTGAAGCACTTATCAGCTGTAACAGGCTGGCTCCCTCGTGATGCTGTTAGAA
TACTAGAGGATCTTATAAGGAAGATAAATATTCCCATCCTCATAGAGTATAGGGATCCTGTGAGAGGCGTTGATAACCCA
CCCACAAAGTTTAATAACAAGGGAGTGATAAGATACTTCCAACTCGTAACAAGGCTTTACGGAGTCCCCAGTTACTGGGA
GCATGATCCCACGCCATTGATCATGTATTCCTTCGCATTCTTCTTCGGGATAATGAATGCTGATGCAGGATACGCCTTAG
CCGGTTTCATATCTATTTTATTAATCATGGATAAACTAGTTGAGAACCCGTATAGTAATGCTTATAAAGAGTTCAAGGGC
CTCCTCATAGTTTCCAATATTATCTCACTAGTACTTGGATTACTCAGTGGTTCATTCTTCGGTGATCTATTGTCCTCCAT
ATTAAATATAAATATACCGGCAATCCTAACGGTGTTTAGTCAACCAGTGGAGTTCATAAAGCTGGCCTTGTTAATAGGGC
TGATACATATTAACATAGCACATGTTCTGGCCACCATGAAGTTCATTAGGGAGAAGAGGAGAGGAGATCTCCTCAACGAG
GTTGGATTATTTATCTCAGAGCTATTCGGAATCCCCTACGTGCTCAAGGTGTTCTTCAGGTATGAGGTACCATTTTTAAC
GTTAATACCGGAGAAAATACTATTATATCTAGCATTGCTAGGCGTCGTGATAGTTATCGTAGGCAACTACTTATCGATGA
GGGGACTTGGATTCCTAATGTGGGTATTCCAGCTCACAGGCATCCTCGGCGATGTCATGAGCTATGTTAGACTAGCCGGT
GTTAGCCTTGCAAGCTTCTATATGGCTAGCTCATTCAATATAATGGTTAAACTAGTTATCAATGGATTGCCAACGATTAT
ACCTGGTGTAGCCGGGGCTATGGTAGCATACATCGTATCGGCACCACTGCTATTACTGATACACCTGTTGGTGATGGTTC
TCTCACAGATGGGTGCATTCGTGCACTCGCTGAGGCTATGTATGCTCGAGTTCCTTATGAAATTCTATGATGGCTCGGGA
CGCGAGTACAATCCATTCTCTATAGTTGCGTTTAAACGTATCGTGGTTTCTTAG

Upstream 100 bases:

>100_bases
TGAGAAAGCCAGGAAAGATGCCGAAAACCTAAGAAATATCCCACAGGAGAGAGTAAGAAAAGCAGTTGAATACGTGGTTA
AAACCGTGGTGGGGCTATAG

Downstream 100 bases:

>100_bases
AAAAGATAAAAGATTATTGAATTTGTTTTTAATCCCCAGATTGGATCTATATAAGAACCAGTTTGCGTATAAGGGTGGTT
AAATGGACCCATTAGCCATG

Product: V-type ATPase, 116 kDa subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I [H]

Number of amino acids: Translated: 657; Mature: 656

Protein sequence:

>657_residues
MGLLLSKPSEMVKINAAFLQADKEKALRLLQEAGVIDIEPVEAEKIVREYERLQSLRERINSLIQKAKGLAINVSITGLE
LSSIEISRIEKDVASLQDEVALLEGKLKHVRETLDSLKMLQTAINPLPDTMETTEIYYEGRHLSSILLTGKRETINELVE
KPGLIKAAHSFKIDEEQVSIIVYVSSQDLNQLLSLASSMGIWYPGRQLLEFIQPHKSIGLLKEYLGKKITELSEEDESLE
GKIVEKIKSHGEILGKYLLIVENYIEYYKVSGITTDLKHLSAVTGWLPRDAVRILEDLIRKINIPILIEYRDPVRGVDNP
PTKFNNKGVIRYFQLVTRLYGVPSYWEHDPTPLIMYSFAFFFGIMNADAGYALAGFISILLIMDKLVENPYSNAYKEFKG
LLIVSNIISLVLGLLSGSFFGDLLSSILNINIPAILTVFSQPVEFIKLALLIGLIHINIAHVLATMKFIREKRRGDLLNE
VGLFISELFGIPYVLKVFFRYEVPFLTLIPEKILLYLALLGVVIVIVGNYLSMRGLGFLMWVFQLTGILGDVMSYVRLAG
VSLASFYMASSFNIMVKLVINGLPTIIPGVAGAMVAYIVSAPLLLLIHLLVMVLSQMGAFVHSLRLCMLEFLMKFYDGSG
REYNPFSIVAFKRIVVS

Sequences:

>Translated_657_residues
MGLLLSKPSEMVKINAAFLQADKEKALRLLQEAGVIDIEPVEAEKIVREYERLQSLRERINSLIQKAKGLAINVSITGLE
LSSIEISRIEKDVASLQDEVALLEGKLKHVRETLDSLKMLQTAINPLPDTMETTEIYYEGRHLSSILLTGKRETINELVE
KPGLIKAAHSFKIDEEQVSIIVYVSSQDLNQLLSLASSMGIWYPGRQLLEFIQPHKSIGLLKEYLGKKITELSEEDESLE
GKIVEKIKSHGEILGKYLLIVENYIEYYKVSGITTDLKHLSAVTGWLPRDAVRILEDLIRKINIPILIEYRDPVRGVDNP
PTKFNNKGVIRYFQLVTRLYGVPSYWEHDPTPLIMYSFAFFFGIMNADAGYALAGFISILLIMDKLVENPYSNAYKEFKG
LLIVSNIISLVLGLLSGSFFGDLLSSILNINIPAILTVFSQPVEFIKLALLIGLIHINIAHVLATMKFIREKRRGDLLNE
VGLFISELFGIPYVLKVFFRYEVPFLTLIPEKILLYLALLGVVIVIVGNYLSMRGLGFLMWVFQLTGILGDVMSYVRLAG
VSLASFYMASSFNIMVKLVINGLPTIIPGVAGAMVAYIVSAPLLLLIHLLVMVLSQMGAFVHSLRLCMLEFLMKFYDGSG
REYNPFSIVAFKRIVVS
>Mature_656_residues
GLLLSKPSEMVKINAAFLQADKEKALRLLQEAGVIDIEPVEAEKIVREYERLQSLRERINSLIQKAKGLAINVSITGLEL
SSIEISRIEKDVASLQDEVALLEGKLKHVRETLDSLKMLQTAINPLPDTMETTEIYYEGRHLSSILLTGKRETINELVEK
PGLIKAAHSFKIDEEQVSIIVYVSSQDLNQLLSLASSMGIWYPGRQLLEFIQPHKSIGLLKEYLGKKITELSEEDESLEG
KIVEKIKSHGEILGKYLLIVENYIEYYKVSGITTDLKHLSAVTGWLPRDAVRILEDLIRKINIPILIEYRDPVRGVDNPP
TKFNNKGVIRYFQLVTRLYGVPSYWEHDPTPLIMYSFAFFFGIMNADAGYALAGFISILLIMDKLVENPYSNAYKEFKGL
LIVSNIISLVLGLLSGSFFGDLLSSILNINIPAILTVFSQPVEFIKLALLIGLIHINIAHVLATMKFIREKRRGDLLNEV
GLFISELFGIPYVLKVFFRYEVPFLTLIPEKILLYLALLGVVIVIVGNYLSMRGLGFLMWVFQLTGILGDVMSYVRLAGV
SLASFYMASSFNIMVKLVINGLPTIIPGVAGAMVAYIVSAPLLLLIHLLVMVLSQMGAFVHSLRLCMLEFLMKFYDGSGR
EYNPFSIVAFKRIVVS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 73747; Mature: 73615

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLLSKPSEMVKINAAFLQADKEKALRLLQEAGVIDIEPVEAEKIVREYERLQSLRERI
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NSLIQKAKGLAINVSITGLELSSIEISRIEKDVASLQDEVALLEGKLKHVRETLDSLKML
HHHHHHHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTAINPLPDTMETTEIYYEGRHLSSILLTGKRETINELVEKPGLIKAAHSFKIDEEQVSI
HHHHCCCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCEEHHHCCCCCCCCEEE
IVYVSSQDLNQLLSLASSMGIWYPGRQLLEFIQPHKSIGLLKEYLGKKITELSEEDESLE
EEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHH
GKIVEKIKSHGEILGKYLLIVENYIEYYKVSGITTDLKHLSAVTGWLPRDAVRILEDLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
KINIPILIEYRDPVRGVDNPPTKFNNKGVIRYFQLVTRLYGVPSYWEHDPTPLIMYSFAF
HCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
FFGIMNADAGYALAGFISILLIMDKLVENPYSNAYKEFKGLLIVSNIISLVLGLLSGSFF
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
GDLLSSILNINIPAILTVFSQPVEFIKLALLIGLIHINIAHVLATMKFIREKRRGDLLNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VGLFISELFGIPYVLKVFFRYEVPFLTLIPEKILLYLALLGVVIVIVGNYLSMRGLGFLM
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVFQLTGILGDVMSYVRLAGVSLASFYMASSFNIMVKLVINGLPTIIPGVAGAMVAYIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
APLLLLIHLLVMVLSQMGAFVHSLRLCMLEFLMKFYDGSGREYNPFSIVAFKRIVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GLLLSKPSEMVKINAAFLQADKEKALRLLQEAGVIDIEPVEAEKIVREYERLQSLRERI
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NSLIQKAKGLAINVSITGLELSSIEISRIEKDVASLQDEVALLEGKLKHVRETLDSLKML
HHHHHHHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTAINPLPDTMETTEIYYEGRHLSSILLTGKRETINELVEKPGLIKAAHSFKIDEEQVSI
HHHHCCCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCEEHHHCCCCCCCCEEE
IVYVSSQDLNQLLSLASSMGIWYPGRQLLEFIQPHKSIGLLKEYLGKKITELSEEDESLE
EEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHH
GKIVEKIKSHGEILGKYLLIVENYIEYYKVSGITTDLKHLSAVTGWLPRDAVRILEDLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
KINIPILIEYRDPVRGVDNPPTKFNNKGVIRYFQLVTRLYGVPSYWEHDPTPLIMYSFAF
HCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
FFGIMNADAGYALAGFISILLIMDKLVENPYSNAYKEFKGLLIVSNIISLVLGLLSGSFF
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
GDLLSSILNINIPAILTVFSQPVEFIKLALLIGLIHINIAHVLATMKFIREKRRGDLLNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VGLFISELFGIPYVLKVFFRYEVPFLTLIPEKILLYLALLGVVIVIVGNYLSMRGLGFLM
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVFQLTGILGDVMSYVRLAGVSLASFYMASSFNIMVKLVINGLPTIIPGVAGAMVAYIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
APLLLLIHLLVMVLSQMGAFVHSLRLCMLEFLMKFYDGSGREYNPFSIVAFKRIVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]