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The map label for this gene is glpA [C]

Identifier: 218884192

GI number: 218884192

Start: 843521

End: 844999

Strand: Reverse

Name: glpA [C]

Synonym: DKAM_0881

Alternate gene names: 218884192

Gene position: 844999-843521 (Counterclockwise)

Preceding gene: 218884193

Following gene: 218884191

Centisome position: 61.89

GC content: 47.73

Gene sequence:

>1479_bases
ATGAGGATAGTTATCATTGGAGCCGGTGTAGTAGGGTTATCCATCGCAAGAGTCCTCAGCATGTATAAGGGACTAGATAT
AGTTGTTGTTGAGAAAGAGCCCGATGTAGGCTGGGGGGCCTCTAAGGCTAATACATCTATAATTCACCCGGGACACGAGG
AAGACCCCGAGTTACACCCTCTTAGAGCGAGACTCTGCGTGGAAGGTAACAAGCTCTGGCGTCAATGGGTTAAGGAGCTG
GATATACCGGCAAAGTGGCCTGGTGAACTAATGGTCTTCACTAACAGCGAGGAAGAGAAGGAAGCGCTGAGATACATTGA
CACAGCCAGAAGAAACAATGTGCCAGGGGTTAGGGCGGTATATGGAGATGAATTAAGGAGACTTGAACCAGCTATAAGCC
CGATGGCTGTGGGGGCAGTATATGCACCCACAGCTGGTAATATATCACCTTTTGAAGCTGTTGCCGCGCTAGCCGAGAAC
CTTGTTGAAAATGGTGGGAGAATACTCGTGAATACACTGGTTAAATCAGTCAGAATTAAAGACAAAGCTGTTGAAGGAGT
TGAAACAAGTGGAGGGTTTATTCAGGCCGACATAGTGATTAATGCTGCGGGTGTTCATGCCGACGAGATTTCCCACAGCG
CTGGTGTCGAAGAGGACTTCGTGATAAGGCCTAGGAAAGGGGAATATATAGTATTTGATGAGGATACCAGCGTTAAACCC
TTAAGGCTTCTGCATACAACACCTACAAGTTTAACCAAAGGAGTTTACGCTATCACGACAACCGGGGGAGACTTACTCAT
AGGTCCTACGGCAGTGGACATGCCATACGAGTTGAAAGAGGATACCTCAACAACACTTGAAGGCATCGAGTATTTACTCA
GGGAAGCAGGTAAACTACTGAGAGAGCTACCTCCTAGATCACTTATCACGAGGACATTTGCTGGTGTAAGACCTGAGCCC
CCACATGGTGAATGGCTGATTAAAGTATACGAGGAGCCATGGGGCTTCATCAATGTTGCAGGGATAAGATCCCCAGGGCT
CACAGCAGCCCCTGCAATAGCATATTATGTAGCAGACATGATCTCTAAATCATACGCGGTGAGCCTGGAGCACAGGAGTG
ACTGGAAGCCTTATAGAAGAGGATTCCTCAGGCTTCACGGTAAATCCCTACGGGAAATAGATGAACTAGTATCGGTAAAC
CCTGATTACGGCGAGGTAATATGCTACTGTAGAACCGTATCAAAGGCGGAGATACTTGAAGCGGTTAAGAGGATTAAGAC
CATAGGAGCGCAGGTAACCCTTGACGGTGTAAAGTTTAGGACTAAAGCTGGATTCGGCAGGTGCCAGGGCTCCTTCTGCA
GGTGGAGGATAGCGGGGATTATTGCTGGCTTGGAGGGTAAGGAGATGCATGAAGTTGTAGTCAAGATGGAGAGATATGGT
TTGGGAGATGTTAAAAAGATGCTGAGAGAGGAAGCCTAG

Upstream 100 bases:

>100_bases
GGATGGGCCCGTGAAGTACCATGGGCCTATGGATATGAGTAAAGACGTTTAATCCCTTGCCTGATTATAGACTGATCATA
GATTACGGGAGGATTCGTGA

Downstream 100 bases:

>100_bases
GATGGAGACCCTTGTATACGATGTAGTCGTCATCGGGGGAGGCCCTGCCGGGATAGCCTCAGCAATAAAAGCCGATAGCC
TTGGCTTGAAGACAGCACTG

Product: Glycerol-3-phosphate dehydrogenase

Products: Dihydroxyacetone phosphate; Ubiquinol-8 [C]

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MRIVIIGAGVVGLSIARVLSMYKGLDIVVVEKEPDVGWGASKANTSIIHPGHEEDPELHPLRARLCVEGNKLWRQWVKEL
DIPAKWPGELMVFTNSEEEKEALRYIDTARRNNVPGVRAVYGDELRRLEPAISPMAVGAVYAPTAGNISPFEAVAALAEN
LVENGGRILVNTLVKSVRIKDKAVEGVETSGGFIQADIVINAAGVHADEISHSAGVEEDFVIRPRKGEYIVFDEDTSVKP
LRLLHTTPTSLTKGVYAITTTGGDLLIGPTAVDMPYELKEDTSTTLEGIEYLLREAGKLLRELPPRSLITRTFAGVRPEP
PHGEWLIKVYEEPWGFINVAGIRSPGLTAAPAIAYYVADMISKSYAVSLEHRSDWKPYRRGFLRLHGKSLREIDELVSVN
PDYGEVICYCRTVSKAEILEAVKRIKTIGAQVTLDGVKFRTKAGFGRCQGSFCRWRIAGIIAGLEGKEMHEVVVKMERYG
LGDVKKMLREEA

Sequences:

>Translated_492_residues
MRIVIIGAGVVGLSIARVLSMYKGLDIVVVEKEPDVGWGASKANTSIIHPGHEEDPELHPLRARLCVEGNKLWRQWVKEL
DIPAKWPGELMVFTNSEEEKEALRYIDTARRNNVPGVRAVYGDELRRLEPAISPMAVGAVYAPTAGNISPFEAVAALAEN
LVENGGRILVNTLVKSVRIKDKAVEGVETSGGFIQADIVINAAGVHADEISHSAGVEEDFVIRPRKGEYIVFDEDTSVKP
LRLLHTTPTSLTKGVYAITTTGGDLLIGPTAVDMPYELKEDTSTTLEGIEYLLREAGKLLRELPPRSLITRTFAGVRPEP
PHGEWLIKVYEEPWGFINVAGIRSPGLTAAPAIAYYVADMISKSYAVSLEHRSDWKPYRRGFLRLHGKSLREIDELVSVN
PDYGEVICYCRTVSKAEILEAVKRIKTIGAQVTLDGVKFRTKAGFGRCQGSFCRWRIAGIIAGLEGKEMHEVVVKMERYG
LGDVKKMLREEA
>Mature_492_residues
MRIVIIGAGVVGLSIARVLSMYKGLDIVVVEKEPDVGWGASKANTSIIHPGHEEDPELHPLRARLCVEGNKLWRQWVKEL
DIPAKWPGELMVFTNSEEEKEALRYIDTARRNNVPGVRAVYGDELRRLEPAISPMAVGAVYAPTAGNISPFEAVAALAEN
LVENGGRILVNTLVKSVRIKDKAVEGVETSGGFIQADIVINAAGVHADEISHSAGVEEDFVIRPRKGEYIVFDEDTSVKP
LRLLHTTPTSLTKGVYAITTTGGDLLIGPTAVDMPYELKEDTSTTLEGIEYLLREAGKLLRELPPRSLITRTFAGVRPEP
PHGEWLIKVYEEPWGFINVAGIRSPGLTAAPAIAYYVADMISKSYAVSLEHRSDWKPYRRGFLRLHGKSLREIDELVSVN
PDYGEVICYCRTVSKAEILEAVKRIKTIGAQVTLDGVKFRTKAGFGRCQGSFCRWRIAGIIAGLEGKEMHEVVVKMERYG
LGDVKKMLREEA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13376331, Length=274, Percent_Identity=27.007299270073, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1788574, Length=490, Percent_Identity=24.4897959183673, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082148, Length=260, Percent_Identity=26.5384615384615, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17565764, Length=281, Percent_Identity=25.6227758007117, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585081, Length=269, Percent_Identity=26.7657992565056, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.1.99.5 [C]

Molecular weight: Translated: 54280; Mature: 54280

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVIIGAGVVGLSIARVLSMYKGLDIVVVEKEPDVGWGASKANTSIIHPGHEEDPELHP
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCH
LRARLCVEGNKLWRQWVKELDIPAKWPGELMVFTNSEEEKEALRYIDTARRNNVPGVRAV
HHHHEEECCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHH
YGDELRRLEPAISPMAVGAVYAPTAGNISPFEAVAALAENLVENGGRILVNTLVKSVRIK
HHHHHHHHHHCCCCCEECEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
DKAVEGVETSGGFIQADIVINAAGVHADEISHSAGVEEDFVIRPRKGEYIVFDEDTSVKP
HHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHCCCCCCEEEECCCCCEEEECCCCCCCC
LRLLHTTPTSLTKGVYAITTTGGDLLIGPTAVDMPYELKEDTSTTLEGIEYLLREAGKLL
EEEEECCCHHHHCCEEEEEECCCCEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
RELPPRSLITRTFAGVRPEPPHGEWLIKVYEEPWGFINVAGIRSPGLTAAPAIAYYVADM
HHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ISKSYAVSLEHRSDWKPYRRGFLRLHGKSLREIDELVSVNPDYGEVICYCRTVSKAEILE
HCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHCEEEEEECCCHHHHHH
AVKRIKTIGAQVTLDGVKFRTKAGFGRCQGSFCRWRIAGIIAGLEGKEMHEVVVKMERYG
HHHHHHHCCCEEEECCEEEEECCCCCCCCCCHHHEEEEHHHCCCCCHHHHHHHHHHHHCC
LGDVKKMLREEA
CHHHHHHHHHCC
>Mature Secondary Structure
MRIVIIGAGVVGLSIARVLSMYKGLDIVVVEKEPDVGWGASKANTSIIHPGHEEDPELHP
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCH
LRARLCVEGNKLWRQWVKELDIPAKWPGELMVFTNSEEEKEALRYIDTARRNNVPGVRAV
HHHHEEECCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHH
YGDELRRLEPAISPMAVGAVYAPTAGNISPFEAVAALAENLVENGGRILVNTLVKSVRIK
HHHHHHHHHHCCCCCEECEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
DKAVEGVETSGGFIQADIVINAAGVHADEISHSAGVEEDFVIRPRKGEYIVFDEDTSVKP
HHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHCCCCCCEEEECCCCCEEEECCCCCCCC
LRLLHTTPTSLTKGVYAITTTGGDLLIGPTAVDMPYELKEDTSTTLEGIEYLLREAGKLL
EEEEECCCHHHHCCEEEEEECCCCEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
RELPPRSLITRTFAGVRPEPPHGEWLIKVYEEPWGFINVAGIRSPGLTAAPAIAYYVADM
HHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ISKSYAVSLEHRSDWKPYRRGFLRLHGKSLREIDELVSVNPDYGEVICYCRTVSKAEILE
HCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHCEEEEEECCCHHHHHH
AVKRIKTIGAQVTLDGVKFRTKAGFGRCQGSFCRWRIAGIIAGLEGKEMHEVVVKMERYG
HHHHHHHCCCEEEECCEEEEECCCCCCCCCCHHHEEEEHHHCCCCCHHHHHHHHHHHHCC
LGDVKKMLREEA
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glycerol 3-phosphate; Ubiquinone-8 [C]

Specific reaction: Glycerol 3-phosphate + Ubiquinone-8 --> Dihydroxyacetone phosphate + Ubiquinol-8 [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]