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The map label for this gene is upp [H]

Identifier: 218884028

GI number: 218884028

Start: 690624

End: 691325

Strand: Direct

Name: upp [H]

Synonym: DKAM_0717

Alternate gene names: 218884028

Gene position: 690624-691325 (Clockwise)

Preceding gene: 218884027

Following gene: 218884031

Centisome position: 50.59

GC content: 50.71

Gene sequence:

>702_bases
GTGAGACACATGGGTAGACTCATAGTCATCGATAACCCGCTAGCTAAATACTATCTAACACTACTCCGTAAACCAGGTAC
AACACCCGGACTCTTCAGGGAGTACATGAGAAAACTTGGATTCATAATGGGCTACGAGGTCTCAAGACTACTCGAGTGGG
GCAGGGTCTTCGTCGACTCCGATCATGGGAGGGCTGAGGGCTTCTATCCATATAAACCGGTTTACATAATAGGGGTGTTA
GGCGCCTCGATACCCTTCACACACGGGTTATGGGATGCCATGCCCTGGGCTGGACTTGGGTTAGTTGCAGCGAGAAGAGT
GATCAGTGGGAACAGGGTTGATGCGGAGATATATTATGAGAGGATGCCGAGCAACCTCACAGCTTACACAGTTATAGTAG
TGGATCCAACGCTTGCCACAGGAAGGACAATGGTGAGGGTAGTTGAAGAAGTGCGTGCCAGGGGAGGAGGAAGAATCATT
GCAGCCACAGTACTCGCCTCCCGCTACGGGGTAGAGTACTTCCACTCAAGGTTCGACGAGATACCATTGTTAGCCATAGA
GGTGGATCCAGTTCTCGATAAAAACTATTTCATTATGCCAGGGATTGGTGACGCAGGAGATAGAAGCCTAAGCGCTGACA
TGGCTTTCGAGCCGAGGCTGGGGCTAGAGTTCAGTGAGCCTGGAGAGGATCGAGTCGAGTAA

Upstream 100 bases:

>100_bases
TCCAAGGATAGCTGAGGAGATAGATAGACAGCTCAGGGACCTCGGCTATAGGATTAATTAAACACAAGCCTTTAACCTCC
TGAAAACATTAAATCTTAAT

Downstream 100 bases:

>100_bases
CCCAGGATCTATACAGGCCTCCACCATCCTTGAGCCCAGGCAGGACTCGATGCCCGGTGTGTAAGGTATGTAGCCAAGGT
ACTCTACATCCCCGAGTACC

Product: putative uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRHMGRLIVIDNPLAKYYLTLLRKPGTTPGLFREYMRKLGFIMGYEVSRLLEWGRVFVDSDHGRAEGFYPYKPVYIIGVL
GASIPFTHGLWDAMPWAGLGLVAARRVISGNRVDAEIYYERMPSNLTAYTVIVVDPTLATGRTMVRVVEEVRARGGGRII
AATVLASRYGVEYFHSRFDEIPLLAIEVDPVLDKNYFIMPGIGDAGDRSLSADMAFEPRLGLEFSEPGEDRVE

Sequences:

>Translated_233_residues
MRHMGRLIVIDNPLAKYYLTLLRKPGTTPGLFREYMRKLGFIMGYEVSRLLEWGRVFVDSDHGRAEGFYPYKPVYIIGVL
GASIPFTHGLWDAMPWAGLGLVAARRVISGNRVDAEIYYERMPSNLTAYTVIVVDPTLATGRTMVRVVEEVRARGGGRII
AATVLASRYGVEYFHSRFDEIPLLAIEVDPVLDKNYFIMPGIGDAGDRSLSADMAFEPRLGLEFSEPGEDRVE
>Mature_233_residues
MRHMGRLIVIDNPLAKYYLTLLRKPGTTPGLFREYMRKLGFIMGYEVSRLLEWGRVFVDSDHGRAEGFYPYKPVYIIGVL
GASIPFTHGLWDAMPWAGLGLVAARRVISGNRVDAEIYYERMPSNLTAYTVIVVDPTLATGRTMVRVVEEVRARGGGRII
AATVLASRYGVEYFHSRFDEIPLLAIEVDPVLDKNYFIMPGIGDAGDRSLSADMAFEPRLGLEFSEPGEDRVE

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Escherichia coli, GI87082118, Length=204, Percent_Identity=24.5098039215686, Blast_Score=87, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321920, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR005765 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 26154; Mature: 26154

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHMGRLIVIDNPLAKYYLTLLRKPGTTPGLFREYMRKLGFIMGYEVSRLLEWGRVFVDS
CCCCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
DHGRAEGFYPYKPVYIIGVLGASIPFTHGLWDAMPWAGLGLVAARRVISGNRVDAEIYYE
CCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCHHHHEE
RMPSNLTAYTVIVVDPTLATGRTMVRVVEEVRARGGGRIIAATVLASRYGVEYFHSRFDE
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCC
IPLLAIEVDPVLDKNYFIMPGIGDAGDRSLSADMAFEPRLGLEFSEPGEDRVE
CCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRHMGRLIVIDNPLAKYYLTLLRKPGTTPGLFREYMRKLGFIMGYEVSRLLEWGRVFVDS
CCCCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
DHGRAEGFYPYKPVYIIGVLGASIPFTHGLWDAMPWAGLGLVAARRVISGNRVDAEIYYE
CCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCHHHHEE
RMPSNLTAYTVIVVDPTLATGRTMVRVVEEVRARGGGRIIAATVLASRYGVEYFHSRFDE
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCC
IPLLAIEVDPVLDKNYFIMPGIGDAGDRSLSADMAFEPRLGLEFSEPGEDRVE
CCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]