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The map label for this gene is arnC [H]

Identifier: 218883917

GI number: 218883917

Start: 568797

End: 569573

Strand: Direct

Name: arnC [H]

Synonym: DKAM_0606

Alternate gene names: 218883917

Gene position: 568797-569573 (Clockwise)

Preceding gene: 218883916

Following gene: 218883918

Centisome position: 41.66

GC content: 44.02

Gene sequence:

>777_bases
ATGATGGTGGGTTATTTAATGAAGGTATCAATATTGTTACCAACATACAATGAGAGAAAAAATATAGGTATACTCATTCC
TTTAATAGATAGTGTTCTAAGAGGTGAGGGGATCGAATACGAGATCATTGTCATAGACGACAACAGCCCCGATGGCACAG
CCGAGGAAGCTTTAAAGCTTTCATCCAGGTTCAACGTCAAAGTCCTTAAGAGACCTGGTAGACTTGGGTTATCCTCAGCC
ATTCATGACGGGGTTAGATATTCCAGTGGTGAAGTAATTGTAGTCATGGACGCGGATCTACAACACCCCCCGGGATACAT
CCCCATGCTTGTCAAGAGGATAGGTGAGTGCGATATCGTCGTGGCTTCGAGATATATACCTGGAGGGAGAAGTGAGGGTT
TTCCACTCGTTAGAAGAATTATTTCAAGGGGCTCAATTCTACTTGCCCATCTAATAGTCCCGGGAACCAGAAAGGTGAGA
GATGCCGTAAGCGGGTTCTTCGCTGCTAAGAGGAGTGTTTTATCTAGGTGGAGGCTTCTGGAGCCCTACGGTTACAAGGT
CCTTGTTGAGATTCTTGGAGAGCTCCAGGATGTAAAAGTATGCGAGGAGCCCATAGTATTTAAAAAACGTGAAAGGGGGT
CTTCGAAGCTTACGGTTAAGGTTATTCTCTCATATATTAAGACAATCTACAGGCTGAATCCACGCGTATTCCTAGGCTAC
GTGTTATTGACTTTGACTATAGTGTTGCTTCTCTCAATAACACTGCTAGCTATATAG

Upstream 100 bases:

>100_bases
GCAGTAAAGGGTACATTCAACGAAGCCCCTGAAACAAGCTAGTGCCCTTGACAAGTTTTATTTTGTTCCACTTATATTCA
GAGAATAAAATGCCGGCTTA

Downstream 100 bases:

>100_bases
CTATGTTTTTATTTTGGTTAGATTGTATCTTTCAAGATACTGAGTTAACCAAGCATTAACGAGGATGTAGTTAATGAGTG
GAAACACAGAGTGGCTTTTA

Product: dolichol-phosphate mannosyltransferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MMVGYLMKVSILLPTYNERKNIGILIPLIDSVLRGEGIEYEIIVIDDNSPDGTAEEALKLSSRFNVKVLKRPGRLGLSSA
IHDGVRYSSGEVIVVMDADLQHPPGYIPMLVKRIGECDIVVASRYIPGGRSEGFPLVRRIISRGSILLAHLIVPGTRKVR
DAVSGFFAAKRSVLSRWRLLEPYGYKVLVEILGELQDVKVCEEPIVFKKRERGSSKLTVKVILSYIKTIYRLNPRVFLGY
VLLTLTIVLLLSITLLAI

Sequences:

>Translated_258_residues
MMVGYLMKVSILLPTYNERKNIGILIPLIDSVLRGEGIEYEIIVIDDNSPDGTAEEALKLSSRFNVKVLKRPGRLGLSSA
IHDGVRYSSGEVIVVMDADLQHPPGYIPMLVKRIGECDIVVASRYIPGGRSEGFPLVRRIISRGSILLAHLIVPGTRKVR
DAVSGFFAAKRSVLSRWRLLEPYGYKVLVEILGELQDVKVCEEPIVFKKRERGSSKLTVKVILSYIKTIYRLNPRVFLGY
VLLTLTIVLLLSITLLAI
>Mature_258_residues
MMVGYLMKVSILLPTYNERKNIGILIPLIDSVLRGEGIEYEIIVIDDNSPDGTAEEALKLSSRFNVKVLKRPGRLGLSSA
IHDGVRYSSGEVIVVMDADLQHPPGYIPMLVKRIGECDIVVASRYIPGGRSEGFPLVRRIISRGSILLAHLIVPGTRKVR
DAVSGFFAAKRSVLSRWRLLEPYGYKVLVEILGELQDVKVCEEPIVFKKRERGSSKLTVKVILSYIKTIYRLNPRVFLGY
VLLTLTIVLLLSITLLAI

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=236, Percent_Identity=36.864406779661, Blast_Score=128, Evalue=5e-30,
Organism=Escherichia coli, GI1788588, Length=219, Percent_Identity=28.7671232876712, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999402, Length=239, Percent_Identity=35.9832635983264, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6325441, Length=265, Percent_Identity=33.2075471698113, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24585265, Length=233, Percent_Identity=36.480686695279, Blast_Score=130, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 28787; Mature: 28787

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVGYLMKVSILLPTYNERKNIGILIPLIDSVLRGEGIEYEIIVIDDNSPDGTAEEALKL
CCHHHEEEEEEEECCCCCCCCCEEEHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHH
SSRFNVKVLKRPGRLGLSSAIHDGVRYSSGEVIVVMDADLQHPPGYIPMLVKRIGECDIV
HCCCCEEEEECCCCCCHHHHHHCCCEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEE
VASRYIPGGRSEGFPLVRRIISRGSILLAHLIVPGTRKVRDAVSGFFAAKRSVLSRWRLL
EEEECCCCCCCCCCHHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EPYGYKVLVEILGELQDVKVCEEPIVFKKRERGSSKLTVKVILSYIKTIYRLNPRVFLGY
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
VLLTLTIVLLLSITLLAI
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMVGYLMKVSILLPTYNERKNIGILIPLIDSVLRGEGIEYEIIVIDDNSPDGTAEEALKL
CCHHHEEEEEEEECCCCCCCCCEEEHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHH
SSRFNVKVLKRPGRLGLSSAIHDGVRYSSGEVIVVMDADLQHPPGYIPMLVKRIGECDIV
HCCCCEEEEECCCCCCHHHHHHCCCEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEE
VASRYIPGGRSEGFPLVRRIISRGSILLAHLIVPGTRKVRDAVSGFFAAKRSVLSRWRLL
EEEECCCCCCCCCCHHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EPYGYKVLVEILGELQDVKVCEEPIVFKKRERGSSKLTVKVILSYIKTIYRLNPRVFLGY
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
VLLTLTIVLLLSITLLAI
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12219091 [H]