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The map label for this gene is purQ [H]

Identifier: 218883832

GI number: 218883832

Start: 486900

End: 487592

Strand: Direct

Name: purQ [H]

Synonym: DKAM_0521

Alternate gene names: 218883832

Gene position: 486900-487592 (Clockwise)

Preceding gene: 218883831

Following gene: 218883833

Centisome position: 35.66

GC content: 46.75

Gene sequence:

>693_bases
ATGGCCGGTAATGTAGCTGTGCTTAAATTTCCTGGTACAAACTGTGATGAAGAGACTCTTAGAGCCCTTAGAAGACATGG
TTTAAACGCTAGAATAGTTTGGCATAGAGACTTCGTATGGAGGGAATATGATGCAATAGTAATACCGGGAGGATTCAGTT
ATGGAGACCATTTAAGAGCCGGTGTAATAGCTGCGAGGACAAGGGCTGTTGAGCAAGTTGTTGAGGCTGCCCTCAACGAA
GTCCCGGTTCTAGGTATATGCAACGGATTCCAGGTGCTTGTCGAGGCTGGATTACTTCCCGGTGCCTTGATACAAAACGA
GCATGGGAGATTCACGTGTAAATGGGTTAGGACGAGAGTGAGAAATCCGAAGGGGCCCTGGCTTCTACTAGTAAGCGATA
AAATGGTTCTAGATATGCCTGTAGCGCACGCGGAGGGACGTTATATCATTGATGAACAGGAATATGTGAAACTCGTTGGT
GAAAATCCTCCACTGATACTATATGAGGATGGTTGGAATCCTAATGGGAGCATGTATAGTATAGCCGGTGTAGCTAGTGG
AAACGGTGCTATACTGGGGTTGATGCCACATCCCGAGAGAGCCGTTGAACCTGAATTGACTCCAAGGGGCTTTAACCCCG
GTGGCAAGCTTGTTTTTGAGAGTATATATTTCGCGCTCAGGAATGGTTGGTGA

Upstream 100 bases:

>100_bases
GAGGCGGAGAGCCCCGAGAAAGCGGTTGAACAAGTTAAACAAGCCTGTCTAGACCTCCGGATATATAATCCGGTAGTACA
TGAGATAGAGGTATTCCTGC

Downstream 100 bases:

>100_bases
AAATGCCGCTGAGTGTTGAAGAGATAGATGAGATCAGGGATATACTTAAGAGAGAGCCAACCCGTGAAGAACTAGTCATG
TTCGAGGCTCATTGGAGCGA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MAGNVAVLKFPGTNCDEETLRALRRHGLNARIVWHRDFVWREYDAIVIPGGFSYGDHLRAGVIAARTRAVEQVVEAALNE
VPVLGICNGFQVLVEAGLLPGALIQNEHGRFTCKWVRTRVRNPKGPWLLLVSDKMVLDMPVAHAEGRYIIDEQEYVKLVG
ENPPLILYEDGWNPNGSMYSIAGVASGNGAILGLMPHPERAVEPELTPRGFNPGGKLVFESIYFALRNGW

Sequences:

>Translated_230_residues
MAGNVAVLKFPGTNCDEETLRALRRHGLNARIVWHRDFVWREYDAIVIPGGFSYGDHLRAGVIAARTRAVEQVVEAALNE
VPVLGICNGFQVLVEAGLLPGALIQNEHGRFTCKWVRTRVRNPKGPWLLLVSDKMVLDMPVAHAEGRYIIDEQEYVKLVG
ENPPLILYEDGWNPNGSMYSIAGVASGNGAILGLMPHPERAVEPELTPRGFNPGGKLVFESIYFALRNGW
>Mature_229_residues
AGNVAVLKFPGTNCDEETLRALRRHGLNARIVWHRDFVWREYDAIVIPGGFSYGDHLRAGVIAARTRAVEQVVEAALNEV
PVLGICNGFQVLVEAGLLPGALIQNEHGRFTCKWVRTRVRNPKGPWLLLVSDKMVLDMPVAHAEGRYIIDEQEYVKLVGE
NPPLILYEDGWNPNGSMYSIAGVASGNGAILGLMPHPERAVEPELTPRGFNPGGKLVFESIYFALRNGW

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=250, Percent_Identity=29.6, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI48994899, Length=227, Percent_Identity=30.3964757709251, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=250, Percent_Identity=26.8, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24582111, Length=230, Percent_Identity=33.9130434782609, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582109, Length=230, Percent_Identity=33.9130434782609, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17137292, Length=230, Percent_Identity=33.9130434782609, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25454; Mature: 25322

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNVAVLKFPGTNCDEETLRALRRHGLNARIVWHRDFVWREYDAIVIPGGFSYGDHLRA
CCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCEEECCCEEEECCCCCCCCHHHH
GVIAARTRAVEQVVEAALNEVPVLGICNGFQVLVEAGLLPGALIQNEHGRFTCKWVRTRV
HHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCEEECCCCCEEEEEEHHHH
RNPKGPWLLLVSDKMVLDMPVAHAEGRYIIDEQEYVKLVGENPPLILYEDGWNPNGSMYS
CCCCCCEEEEEECCEEEEECCCCCCCCEEECHHHHHEEECCCCCEEEEECCCCCCCCEEE
IAGVASGNGAILGLMPHPERAVEPELTPRGFNPGGKLVFESIYFALRNGW
EEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGNVAVLKFPGTNCDEETLRALRRHGLNARIVWHRDFVWREYDAIVIPGGFSYGDHLRA
CCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCEEECCCEEEECCCCCCCCHHHH
GVIAARTRAVEQVVEAALNEVPVLGICNGFQVLVEAGLLPGALIQNEHGRFTCKWVRTRV
HHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCEEECCCCCEEEEEEHHHH
RNPKGPWLLLVSDKMVLDMPVAHAEGRYIIDEQEYVKLVGENPPLILYEDGWNPNGSMYS
CCCCCCEEEEEECCEEEEECCCCCCCCEEECHHHHHEEECCCCCEEEEECCCCCCCCEEE
IAGVASGNGAILGLMPHPERAVEPELTPRGFNPGGKLVFESIYFALRNGW
EEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA