BacMap

Definition	Methylobacterium chloromethanicum CM4, complete genome.
Accession	NC_011757
Length	5,777,908

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The map label for this gene is fabG [H]

Identifier: 218532930

GI number: 218532930

Start: 5407283

End: 5408026

Strand: Reverse

Name: fabG [H]

Synonym: Mchl_5053

Alternate gene names: 218532930

Gene position: 5408026-5407283 (Counterclockwise)

Preceding gene: 218532931

Following gene: 218532929

Centisome position: 93.6

GC content: 70.83

Gene sequence:

>744_bases
GTGAGCGACGATCTCAAGACCGGACGCCTCGTCGTCGTCACGGGCGCGAGCCGGGGGCTCGGCCTCGCCATGGCCGAAAC
GCTCGCCGCCGACGGGTTTCGCGTGGTCGCGCTTGCCCGGCGCCCGAGCGAGGCGCTGGAGGCGGCGCAAGTGGCTGCCC
CCGGCCGGATCGCCTTCATGGCCGCGGATCTCGGCGAGATCGATGCACTCCAGGCTCTCGCCCAGAGAATCCGGGCCGAG
CACGGGCCGGTCTACGGCCTCGTCAACAACGCCGCGCTCGGCACGCCCGGCCTGCTGACGACGATGCCGGCAAGCAAGAT
CGCCGAACTCGTCCACCTCAACACCCTCGCGCCGATGGTGCTGACCAAGTACCTCGCCCGTGGGATGATGACGGCCGGCG
CCGGCCGCATCGTCAATGTCAGCTCGATCATCGCCTTCACCGGCTACAACGCCCTGTCGGTCTACGCCGCGACCAAGGCC
TCGATGATCGGCTTCACCAAGTCGCTCGCCCGCGAGGTCGGGCGGCTCGGGGTGACGGTGAACGCGGTGGCGCCCGGCTT
CATCGAGACGGCGATGACCGGCGAGATGGACGAGGCGGAGCGCGGGCGCGTGGCCAACCGCAGCGCCCTCAAGCGGCTGG
CCGAGCCGCAGGACGTGGCCGACGCCGTCGCCTACCTGATGTCGGACCGCGCCCGCAACGTCACCGGCACCGTTCTGACC
ATCGATGCCGGCAGCACCGCCTGA

Upstream 100 bases:

>100_bases
ATTGTCGCCCGCGCCTGGCCGGACACAAGGTGCCGGCGAGCGTGAAATTCGTGGATGCGCTGCCGATCACGTCGGGCGGC
AAGCTGGTGCGGAGGGGCGC

Downstream 100 bases:

>100_bases
AGCCGGCCAGCGACCTTGAGCCAGGACTTCACTCGCCAGAAATTGGCGCGAAATCAATATATCTTGGATGGATTGGGCGG
AAAATCGACGCCTATACCAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSDDLKTGRLVVVTGASRGLGLAMAETLAADGFRVVALARRPSEALEAAQVAAPGRIAFMAADLGEIDALQALAQRIRAE
HGPVYGLVNNAALGTPGLLTTMPASKIAELVHLNTLAPMVLTKYLARGMMTAGAGRIVNVSSIIAFTGYNALSVYAATKA
SMIGFTKSLAREVGRLGVTVNAVAPGFIETAMTGEMDEAERGRVANRSALKRLAEPQDVADAVAYLMSDRARNVTGTVLT
IDAGSTA

Sequences:

>Translated_247_residues
MSDDLKTGRLVVVTGASRGLGLAMAETLAADGFRVVALARRPSEALEAAQVAAPGRIAFMAADLGEIDALQALAQRIRAE
HGPVYGLVNNAALGTPGLLTTMPASKIAELVHLNTLAPMVLTKYLARGMMTAGAGRIVNVSSIIAFTGYNALSVYAATKA
SMIGFTKSLAREVGRLGVTVNAVAPGFIETAMTGEMDEAERGRVANRSALKRLAEPQDVADAVAYLMSDRARNVTGTVLT
IDAGSTA
>Mature_246_residues
SDDLKTGRLVVVTGASRGLGLAMAETLAADGFRVVALARRPSEALEAAQVAAPGRIAFMAADLGEIDALQALAQRIRAEH
GPVYGLVNNAALGTPGLLTTMPASKIAELVHLNTLAPMVLTKYLARGMMTAGAGRIVNVSSIIAFTGYNALSVYAATKAS
MIGFTKSLAREVGRLGVTVNAVAPGFIETAMTGEMDEAERGRVANRSALKRLAEPQDVADAVAYLMSDRARNVTGTVLTI
DAGSTA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=34.3220338983051, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=31.3008130081301, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=35.5102040816327, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=30.0411522633745, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=27.5720164609054, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=29.5081967213115, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI19743808, Length=236, Percent_Identity=28.3898305084746, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7657478, Length=193, Percent_Identity=32.1243523316062, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=25.296442687747, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI50726952, Length=189, Percent_Identity=29.1005291005291, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4557649, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157739938, Length=196, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI31542939, Length=254, Percent_Identity=25.9842519685039, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706523, Length=204, Percent_Identity=27.9411764705882, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI7706318, Length=204, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=31.1827956989247, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI166795268, Length=206, Percent_Identity=31.5533980582524, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI66933014, Length=143, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=30.6122448979592, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=27.1317829457364, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI142976729, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI40548397, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI214010158, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI214010156, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI22758144, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI226371731, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=38.655462184874, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=31.4285714285714, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=27.6, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.0158102766798, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.9838056680162, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.0204081632653, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=26.9709543568465, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=29.4820717131474, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1786701, Length=226, Percent_Identity=27.4336283185841, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=31.5573770491803, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=26.8, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=28.4552845528455, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=30.5220883534137, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787891, Length=244, Percent_Identity=27.4590163934426, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787820, Length=228, Percent_Identity=26.7543859649123, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=24.3137254901961, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=30.7053941908714, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=33.195020746888, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=29.5546558704453, Blast_Score=106, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=29.277566539924, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=30.2040816326531, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.5546558704453, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=26.615969581749, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=234, Percent_Identity=29.9145299145299, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=233, Percent_Identity=30.0429184549356, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.030303030303, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=28.030303030303, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=28.8, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=239, Percent_Identity=25.9414225941423, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=26.6917293233083, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=25.9109311740891, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=28.0155642023346, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.030303030303, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=28.3018867924528, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=217, Percent_Identity=26.2672811059908, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=190, Percent_Identity=26.8421052631579, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=242, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=31.0483870967742, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=34.9593495934959, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=33.0645161290323, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=32, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=32.295719844358, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644337, Length=117, Percent_Identity=41.8803418803419, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=27.710843373494, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI116007236, Length=231, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571387, Length=238, Percent_Identity=27.3109243697479, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356301, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17737361, Length=247, Percent_Identity=28.7449392712551, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648944, Length=230, Percent_Identity=29.1304347826087, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=202, Percent_Identity=28.2178217821782, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161076933, Length=202, Percent_Identity=28.2178217821782, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641232, Length=232, Percent_Identity=26.7241379310345, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007238, Length=209, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25573; Mature: 25442

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDLKTGRLVVVTGASRGLGLAMAETLAADGFRVVALARRPSEALEAAQVAAPGRIAFM
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCEEEEE
AADLGEIDALQALAQRIRAEHGPVYGLVNNAALGTPGLLTTMPASKIAELVHLNTLAPMV
ECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHH
LTKYLARGMMTAGAGRIVNVSSIIAFTGYNALSVYAATKASMIGFTKSLAREVGRLGVTV
HHHHHHHHHHHCCCCCEEEHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEE
NAVAPGFIETAMTGEMDEAERGRVANRSALKRLAEPQDVADAVAYLMSDRARNVTGTVLT
ECCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEE
IDAGSTA
EECCCCC
>Mature Secondary Structure 
SDDLKTGRLVVVTGASRGLGLAMAETLAADGFRVVALARRPSEALEAAQVAAPGRIAFM
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCEEEEE
AADLGEIDALQALAQRIRAEHGPVYGLVNNAALGTPGLLTTMPASKIAELVHLNTLAPMV
ECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHH
LTKYLARGMMTAGAGRIVNVSSIIAFTGYNALSVYAATKASMIGFTKSLAREVGRLGVTV
HHHHHHHHHHHCCCCCEEEHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEE
NAVAPGFIETAMTGEMDEAERGRVANRSALKRLAEPQDVADAVAYLMSDRARNVTGTVLT
ECCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEE
IDAGSTA
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]