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The map label for this gene is gpt [H]

Identifier: 218710383

GI number: 218710383

Start: 2588368

End: 2588832

Strand: Reverse

Name: gpt [H]

Synonym: VS_2420

Alternate gene names: 218710383

Gene position: 2588832-2588368 (Counterclockwise)

Preceding gene: 218710384

Following gene: 218710382

Centisome position: 78.47

GC content: 47.1

Gene sequence:

>465_bases
ATGAGCAACAAATTCGTTATCACTTGGGACAACATGCAGACTTACTGCCGTCAACTTGCTGAAAAGCAAATGCCAGCAGA
GCAGTGGAAAGGCATCTGGGCAGTGAGCCGTGGTGGTTTGGTTCCTGGTGCAATCTTGGCTCGTGAGCTAGGTATTCGTC
ACGTAGATACGATTTGTATTTCTAGCTACGACCACGATCACCAACGTGATATGACAGTCGTTAAAGCACCTGAAGGTGAC
GGCGAAGGCTTCCTAATCGTTGAAGATCTTGTTGATAGTGGTGACACTGCACGCAAGCTTCGTGAAATGTATCCGAAAGC
GAAACTGATCGCTGTGTGTGCAAAGCCATCTGGTGCTGATTTGCTAGACGAGTACATCGTTGATATCGCTCAAGACACAT
GGATTGAGCAACCTTGGGATACTAGCCTAAGCTACGTTGAGCCGGTAAATCGCAAGTCAAAATAA

Upstream 100 bases:

>100_bases
ATATACTTTCGCTTAATCGTCTAGATTTCTGCTTAATCGCTGAAGAGGCTATGTTTGAAATAGCCTCTAATAACATGACA
AAATTATTAGGTTTTATACT

Downstream 100 bases:

>100_bases
GCGTAAACTTAGTTTTTTGAGAAATGACCCTTTATAGGGTCATTTTTTTTTATATGATTAGTAACAACCATTTCTTATTA
AGTATCCCAATGTCTGAATC

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSNKFVITWDNMQTYCRQLAEKQMPAEQWKGIWAVSRGGLVPGAILARELGIRHVDTICISSYDHDHQRDMTVVKAPEGD
GEGFLIVEDLVDSGDTARKLREMYPKAKLIAVCAKPSGADLLDEYIVDIAQDTWIEQPWDTSLSYVEPVNRKSK

Sequences:

>Translated_154_residues
MSNKFVITWDNMQTYCRQLAEKQMPAEQWKGIWAVSRGGLVPGAILARELGIRHVDTICISSYDHDHQRDMTVVKAPEGD
GEGFLIVEDLVDSGDTARKLREMYPKAKLIAVCAKPSGADLLDEYIVDIAQDTWIEQPWDTSLSYVEPVNRKSK
>Mature_153_residues
SNKFVITWDNMQTYCRQLAEKQMPAEQWKGIWAVSRGGLVPGAILARELGIRHVDTICISSYDHDHQRDMTVVKAPEGDG
EGFLIVEDLVDSGDTARKLREMYPKAKLIAVCAKPSGADLLDEYIVDIAQDTWIEQPWDTSLSYVEPVNRKSK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=152, Percent_Identity=63.1578947368421, Blast_Score=221, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 17383; Mature: 17252

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKFVITWDNMQTYCRQLAEKQMPAEQWKGIWAVSRGGLVPGAILARELGIRHVDTICI
CCCCEEEEECCHHHHHHHHHHHCCCHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHH
SSYDHDHQRDMTVVKAPEGDGEGFLIVEDLVDSGDTARKLREMYPKAKLIAVCAKPSGAD
CCCCCCCCCCEEEEECCCCCCCCEEEEHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCHH
LLDEYIVDIAQDTWIEQPWDTSLSYVEPVNRKSK
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
SNKFVITWDNMQTYCRQLAEKQMPAEQWKGIWAVSRGGLVPGAILARELGIRHVDTICI
CCCEEEEECCHHHHHHHHHHHCCCHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHH
SSYDHDHQRDMTVVKAPEGDGEGFLIVEDLVDSGDTARKLREMYPKAKLIAVCAKPSGAD
CCCCCCCCCCEEEEECCCCCCCCEEEEHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCHH
LLDEYIVDIAQDTWIEQPWDTSLSYVEPVNRKSK
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA